Non-classical monocytes predict progression of carotid artery bifurcation intima-media thickness in HIV-infected individuals on stable antiretroviral therapy

References

• Deeks SG, Lewin SR, Havlir DV. The end of AIDS: HIV infection as a chronic disease. Lancet. 2013;382:1525–1533.10.1016/S0140-6736(13)61809-7
   PubMed Web of Science ®Google Scholar
• Koskinas KC, Chatzizisis YS, Baker AB, et al. The role of low endothelial shear stress in the conversion of atherosclerotic lesions from stable to unstable plaque. Curr Opin Cardiol. 2009;24:580–590.
   PubMed Web of Science ®Google Scholar
• Hodis HN, Mack WJ, LaBree L, et al. The role of carotid arterial intima-media thickness in predicting clinical coronary events. Ann Intern Med. 1998;128:262–269.10.7326/0003-4819-128-4-199802150-00002
   PubMed Web of Science ®Google Scholar
• Stein JH, Korcarz CE, Hurst RT, et al. Use of carotid ultrasound to identify subclinical vascular disease and evaluate cardiovascular disease risk: a consensus statement from the American society of echocardiography carotid intima-media thickness task force. endorsed by the society for vascular medicine. J Am Soc Echocardiogr. 2008;21:93–111; quiz 189-190.
   PubMed Web of Science ®Google Scholar
• Chironi G, Escaut L, Gariepy J, et al. Carotid intima-media thickness in heavily pretreated HIV-infected PATIENTS. J Acquir Immune Defic Syndr. 2003;32:490–493.10.1097/00126334-200304150-00004
   PubMed Web of Science ®Google Scholar
• Currier JS, Kendall MA, Henry WK, et al. Progression of carotid artery intima-media thickening in HIV-infected and uninfected adults. AIDS. 2007;21:1137–1145.10.1097/QAD.0b013e32811ebf79
   PubMed Web of Science ®Google Scholar
• Malek AM, Alper SL, Izumo S. Hemodynamic shear stress and its role in atherosclerosis. J Am Med Assoc. 1999;282:2035–2042.10.1001/jama.282.21.2035
   PubMed Web of Science ®Google Scholar
• Liu Y, Chen BP, Lu M, et al. Shear stress activation of SREBP1 in endothelial cells is mediated by integrins. Arterioscler Thromb Vasc Biol. 2002;22:76–81.10.1161/hq0102.101822
   PubMed Web of Science ®Google Scholar
• McNally JS, Davis ME, Giddens DP, et al. Role of xanthine oxidoreductase and NAD(P)H oxidase in endothelial superoxide production in response to oscillatory shear stress. Am J Physiol – Heart Circ Physiol. 2003;285:H2290–H2297.10.1152/ajpheart.00515.2003
   PubMed Web of Science ®Google Scholar
• Chatzizisis YS, Coskun AU, Jonas M, et al. Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodeling: Molecular, cellular, and vascular behavior. J Am Coll Cardiol. 2007;49:2379–2393.10.1016/j.jacc.2007.02.059
   PubMed Web of Science ®Google Scholar
• Hsue PY, Ordovas K, Lee T, et al. Carotid intima-media thickness among human immunodeficiency virus-infected patients without coronary calcium. Am J Cardiol. 2012;109:742–747.10.1016/j.amjcard.2011.10.036
   PubMed Web of Science ®Google Scholar
• Westhorpe CL, Maisa A, Spelman T, et al. Associations between surface markers on blood monocytes and carotid atherosclerosis in HIV-positive individuals. Immunol Cell Biol. 2014;92:133–138.10.1038/icb.2013.84
   PubMed Web of Science ®Google Scholar
• Ghattas A, Griffiths HR, Devitt A, et al. Monocytes in coronary artery disease and atherosclerosis: Where are we now? J Am Coll Cardiol. 2013;62:1541–1551.10.1016/j.jacc.2013.07.043
   PubMed Web of Science ®Google Scholar
• Burdo TH, Lackner A, Williams KC. Monocyte/macrophages and their role in HIV neuropathogenesis. Immunol Rev. 2013;254:102–113.
   PubMed Web of Science ®Google Scholar
• Ziegler-Heitbrock L, Ancuta P, Crowe S, et al. Nomenclature of monocytes and dendritic cells in blood. Blood. 2010;116:e74–e80.10.1182/blood-2010-02-258558
   PubMed Web of Science ®Google Scholar
• Jalbert E, Crawford TQ, D’Antoni ML, et al. IL-1Beta enriched monocytes mount massive IL-6 responses to common inflammatory triggers among chronically HIV-1 infected adults on stable anti-retroviral therapy at risk for cardiovascular disease. PLoS ONE. 2013;8:e75500.10.1371/journal.pone.0075500
   PubMed Web of Science ®Google Scholar
• Barbour JD, Jalbert EC, Chow DC, et al. Reduced CD14 expression on classical monocytes and vascular endothelial adhesion markers independently associate with carotid artery intima media thickness in chronically HIV-1 infected adults on virologically suppressive anti-retroviral therapy. Atherosclerosis. 2014;232:52–58.10.1016/j.atherosclerosis.2013.10.021
   PubMed Web of Science ®Google Scholar
• Gordon S, Taylor PR. Monocyte and macrophage heterogeneity. Nat Rev Immunol. 2005;5:953–964.10.1038/nri1733
   PubMed Web of Science ®Google Scholar
• Strauss-Ayali D, Conrad SM, Mosser DM. Monocyte subpopulations and their differentiation patterns during infection. J Leukoc Biol. 2007;82:244–252.10.1189/jlb.0307191
   PubMed Web of Science ®Google Scholar
• Geissmann F, Jung S, Littman DR. Blood monocytes consist of two principal subsets with distinct migratory properties. Immunity. 2003;19:71–82.
   PubMed Web of Science ®Google Scholar
• Ziegler-Heitbrock L. The CD14+ CD16+ blood monocytes: Their role in infection and inflammation. J Leukoc Biol. 2007;81:584–592.
   PubMed Web of Science ®Google Scholar
• Seidler S, Zimmermann HW, Bartneck M, et al. Age-dependent alterations of monocyte subsets and monocyte-related chemokine pathways in healthy adults. BMC Immunol. 2010;11:30.10.1186/1471-2172-11-30
   PubMed Web of Science ®Google Scholar
• Ellery PJ, Tippett E, Chiu YL, et al. The CD16+ monocyte subset is more permissive to infection and preferentially harbors HIV-1 in vivo. J Immunol. 2007;178:6581–6589.10.4049/jimmunol.178.10.6581
   PubMed Web of Science ®Google Scholar
• Funderburg NT, Zidar DA, Shive C, et al. Shared monocyte subset phenotypes in HIV-1 infection and in uninfected subjects with acute coronary syndrome. Blood. 2012;120:4599–4608.10.1182/blood-2012-05-433946
   PubMed Web of Science ®Google Scholar
• Han J, Wang B, Han N, et al. CD14highCD16+ rather than CD14lowCD16+ monocytes correlate with disease progression in chronic HIV-infected patients. J Acquir Immune Defic Syndr. 2009;52:553–559.10.1097/QAI.0b013e3181c1d4fe
   PubMed Web of Science ®Google Scholar
• Min D, Brooks B, Wong J, et al. Alterations in monocyte CD16 in association with diabetes complications. Mediators Inflamm. 2012;2012:649083.
   PubMed Web of Science ®Google Scholar
• Corrales JJ, Almeida M, Burgo RM, et al. Decreased production of inflammatory cytokines by circulating monocytes and dendritic cells in type 2 diabetic men with atherosclerotic complications. J Diabetes Complicat. 2007;21:41–49.10.1016/j.jdiacomp.2005.09.006
   PubMed Web of Science ®Google Scholar
• Pandzic Jaksic V, Gizdic B, Miletic Z, et al. Association of monocyte CCR2 expression with obesity and insulin resistance in postmenopausal women. Clin Invest Med. 2013;36:E24–31.
   PubMed Web of Science ®Google Scholar
• Yang M, Gan H, Shen Q, et al. Proinflammatory CD14+CD16+ monocytes are associated with microinflammation in patients with type 2 diabetes mellitus and diabetic nephropathy uremia. Inflammation. 2012;35:388–396.10.1007/s10753-011-9374-9
   PubMed Web of Science ®Google Scholar
• Shikuma CM, Seto T, Liang CY, et al. Vitamin D levels and markers of arterial dysfunction in HIV. AIDS Res Hum Retroviruses. 2012;28:793–797.
   Google Scholar
• Third Report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III) final report. Circulation. 2002;106:3143–3421.
   PubMed Web of Science ®Google Scholar
• Shikuma CM, Chow DC, Gangcuangco LM, et al. Monocytes expand with immune dysregulation and is associated with insulin resistance in older individuals with chronic HIV. PLoS ONE. 2014;9:e90330.10.1371/journal.pone.0090330
   PubMed Web of Science ®Google Scholar
• Ndhlovu LC, Umaki T, Chew GM, et al. Treatment intensification with maraviroc (CCR5 antagonist) leads to declines in CD16-expressing monocytes in cART-suppressed chronic HIV-infected subjects and is associated with improvements in neurocognitive test performance: Implications for HIV-associated neurocognitive disease (HAND). J Neurovirol. 2014;20:571–582.10.1007/s13365-014-0279-x
   PubMed Web of Science ®Google Scholar
• Lang S, Mary-Krause M, Cotte L, et al. Increased risk of myocardial infarction in HIV-infected patients in France, relative to the general population. AIDS. 2010;24:1228–1230.10.1097/QAD.0b013e328339192f
   PubMed Web of Science ®Google Scholar
• Durand M, Sheehy O, Baril JG, et al. Association between HIV infection, antiretroviral therapy, and risk of acute myocardial infarction: A cohort and nested case-control study using Quebec’s public health insurance database. J Acquir Immune Defic Syndr. 2011;57:245–253.10.1097/QAI.0b013e31821d33a5
   PubMed Web of Science ®Google Scholar
• Freiberg MS, Chang CC, Kuller LH, et al. HIV infection and the risk of acute myocardial infarction. J Am Med Assoc Intern Med. 2013;173:614–622.10.1001/jamainternmed.2013.3728
   Web of Science ®Google Scholar
• Womack JA, Chang CC, So-Armah KA, et al. HIV infection and cardiovascular disease in women. J Am Heart Assoc. 2014;3:e001035.
   PubMed Web of Science ®Google Scholar
• Tawakol A, Lo J, Zanni MV, et al. Increased arterial inflammation relates to high-risk coronary plaque morphology in HIV-infected patients. J Acquir Immune Defic Syndr. 2014;66:164–171.
   PubMed Web of Science ®Google Scholar
• Subramanian S, Tawakol A, Burdo TH, et al. Arterial inflammation in patients with HIV. J Am Med Assoc. 2012;308:379–386.10.1001/jama.2012.6698
   PubMed Web of Science ®Google Scholar
• Gautier EL, Jakubzick C, Randolph GJ. Regulation of the migration and survival of monocyte subsets by chemokine receptors and its relevance to atherosclerosis. Arterioscler Thromb Vasc Biol. 2009;29:1412–1418.
   PubMed Web of Science ®Google Scholar
• Coll B, Parra S, Alonso-Villaverde C, et al. HIV-infected patients with lipodystrophy have higher rates of carotid atherosclerosis: The role of monocyte chemoattractant protein-1. Cytokine. 2006;34:51–55.10.1016/j.cyto.2006.03.013
   PubMed Web of Science ®Google Scholar
• Floris-Moore M, Fayad ZA, Berman JW, et al. Association of HIV viral load with monocyte chemoattractant protein-1 and atherosclerosis burden measured by magnetic resonance imaging. AIDS. 2009;23:941–949.10.1097/QAD.0b013e328329c76b
   PubMed Web of Science ®Google Scholar
• Williams DW, Byrd D, Rubin LH, et al. CCR2 on CD14(+)CD16(+) monocytes is a biomarker of HIV-associated neurocognitive disorders. Neurol Neuroimmunol Neuroinflam. 2014;1:e36.
   PubMedGoogle Scholar
• Ndhlovu LC, D’Antoni ML, Ananworanich J, et al. Loss of CCR2 expressing non-classical monocytes are associated with cognitive impairment in antiretroviral therapy-naive HIV-infected Thais. J Neuroimmunol. 2015;288:25–33.10.1016/j.jneuroim.2015.08.020
   PubMed Web of Science ®Google Scholar
• Ross AC, Rizk N, O’Riordan MA, et al. Relationship between inflammatory markers, endothelial activation markers, and carotid intima‐media thickness in HIV‐infected patients receiving antiretroviral therapy. Clin Infect Dis. 2009;49:1119–1127.10.1086/599190
   PubMed Web of Science ®Google Scholar
• Hamirani YS, Pandey S, Rivera JJ, et al. Markers of inflammation and coronary artery calcification: a systematic review. Atherosclerosis. 2008;201:1–7.
   PubMed Web of Science ®Google Scholar
• Deo R, Khera A, McGuire DK, et al. Association among plasma levels of monocyte chemoattractant protein-1, traditional cardiovascular risk factors, and subclinical atherosclerosis. J Am Coll Cardiol. 2004;44:1812–1818.10.1016/j.jacc.2004.07.047
   PubMed Web of Science ®Google Scholar