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Original Articles

Relative Cancer Potencies of Selected Dioxin-Like Compounds on a Body-Burden Basis: Comparison to Current Toxic Equivalency Factors (TEFs)

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Pages 907-917 | Received 10 Mar 2005, Accepted 13 Jul 2005, Published online: 24 Feb 2007

REFERENCES

  • Bailer, A. J., and Portier, C. J., 1988. Effects of treatment-induced mortality and tumor-induced mortality on tests for carcinogenicity in small samples, Biometrics 44 (1988), pp. 417–431, [INFOTRIEVE][CSA].
  • DeVito, M.J., Ross, D.G., Dupuy, A.E., Ferrario, J., McDaniel, D., and Birnbaum, L. S., 1998. Dose-response relationships for disposition and hepatic sequestration of polyhalogenated dibenzo-p-dioxins, dibenzofurans, and biphenyls following subchronic treatment in mice, Toxicol. Sci 46 (1998), pp. 223–234, [INFOTRIEVE][CSA][CROSSREF].
  • Diliberto, J. J., Burgin, D. E., and Birnbaum, L. S., 1999. Effects of CYP1A2 on disposition of 2,3,7, 8-tetrachlorodibenzo-p-dioxin, 2,3,4,7,8-pentachlorodibenzofuran, and 2,2′,4,4′,5,5′-hexachlorobiphenyl in CYP1A2 knockout and parental (C57BL/6N and 129/Sv) strains of mice, Toxicol. Appl. Pharmacol 159 (1999), pp. 52–64, [INFOTRIEVE][CSA][CROSSREF].
  • Diliberto, J. J., DeVito, M. J., Ross, D. G., and Birnbaum, L. S., 2001. Subchronic exposure of [3H]- 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in female B6C3F1 mice: Relationship of steady-state levels to disposition and metabolism, Toxicol. Sci 61 (2001), pp. 241–255, [INFOTRIEVE][CSA][CROSSREF].
  • http://europa.eu.int/comm/food/fs/sc/scf/out90_en.pdf, European Commission Scientific Committee on Foods. 2001. Opinion of the Scientific Committee on Food on the risk assessment of dioxins and dioxin-like PCBs in food. Update based on new scientific information available since the adoption of the SCF opinion of 22nd November 2000. Brussels, Belgium: European Commisssion. Rep. CS/CNTM/DIOXIN/20 final.
  • Hurst, C. H., DeVito, M. J., and Birnbaum, L. S., 2000. Tissue disposition of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in maternal and developing Long-Evans rats following subchronic exposure, Toxicol. Sci 57 (2000), pp. 275–283, [INFOTRIEVE][CSA][CROSSREF].
  • http://www.who.int/ipcs/food/jecfa/summaries/en/summary_57.pdf, Joint FAO/WHO Expert Committee on Food Additives. 2001. Fifty-seventh meeting Rome, 5–14 June 2001. Summary and conclusions.
  • Liang, H. C., McKinnon, R. A., and Nebert, D. W., 1997. Sensitivity of CYP1A1 mRNA inducibility by dioxin is the same in Cyp1a2(+/+) wild-type and Cyp1a2(−/−) null mutant mice, Biochem. Pharmacol 54 (1997), pp. 1127–1131, [INFOTRIEVE][CSA][CROSSREF].
  • National Toxicology Program, 2004a. Draft NTP technical report on the toxicology and carcinogenesis studies of 2,3,4,7,8-pentachlorodibenzofuran (PeCDF) (CAS No. 57117-31-4) in female Harlan Sprague-Dawley rats (Gavage study). NTP TR 525 National Toxicology Program; 2004a.
  • National Toxicology Program, 2004b. Draft NTP technical report on the toxicology and carcinogenesis studies of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) (CAS No. 1746-01-6) in female Harlan Sprague-Dawley rats (Gavage study). NTP TR 521 National Toxicology Program; 2004b.
  • http://ntp-server.niehs.nih.gov, National Toxicology Program. 2004c. Draft NTP technical report on the toxicology and carcinogenesis studies of 3,3′4,4′,5-pentachlorobiphenyl (PCB 126) (CAS No. 57465-28-8) in female Harlan Sprague-Dawley rats (Gavage study). NTP TR 520 National Toxicology Program, Research Triangle Park, NC.
  • National Toxicology Program, 2004d. Draft NTP technical report on the toxicology and carcinogenesis studies of a mixture of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) (CAS No. 1746.01-6), 2,3,4,7,8-pentachlorodibenzofuran (PeCDF) (CAS No. 57117-31-4), and 3,3’4,4’,5-pentachlorobiphenyl (PCB 126) (CAS No. 57465-28-8) in female Harlan Sprague-Dawley rats (Gavage studies). NTP TR 526. National Toxicology Program; 2004d.
  • Slezak, B. P., Diliberto, J. J., and Birnbaum, L. S., 1999. 2,3,7,8-Tetrachlorodibenzo-p-dioxin-mediated oxidative stress in CYP1A2 knockout (CYP1A2−/−) mice, Biochem. Biophys. Res. Commun 264 (1999), pp. 376–379, [INFOTRIEVE][CSA][CROSSREF].
  • U.S. Environmental Protection Agency, 2003a. Exposure and human health reassessment of 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds. NAS review draft. Washington, DC: National Center for Environmental Assessment, U.S. Environmental Protection Agency; 2003a.
  • https://www.epa.gov/ncea/raf/cancer2003.htm, U.S. Environmental Protection Agency. 2003b. Draft final guidelines for carcinogen risk assessment. EPA/630/P-03/001A. Washington, DC: National Center for Environmental Assessment, U.S. Environmental Protection Agency.
  • van Birgelen, A. P., DeVito, M. J., Akins, J. M., Ross, D. G., Diliberto, J. J., and Birnbaum, L. S., 1996. Relative potencies of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls derived from hepatic porphyrin accumulation in mice, Toxicol. Appl. Pharmacol 138 (1996), pp. 98–109, [INFOTRIEVE][CSA][CROSSREF].
  • Van den Berg, M., Birnbaum, L., Bosveld, A. T., Brunstrom, B., Cook, P., Feeley, M., Giesy, J. P., Hanberg, A., Hasegawa, R., Kennedy, S. W., Kubiak, T., Larsen, J. C., van Leeuwen, F. X., Liem, A. K., Nolt, C., Peterson, R. E., Poellinger, L., Safe, S., Schrenk, D., Tillitt, D., Tysklind, M., Younes, M., Waern, F., and Zacharewski, T., 1998. Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife, Environ. Health Perspect 106 (1998), pp. 775–792, [PUBMED][INFOTRIEVE][CSA].
  • Waern, F., Flodstrom, S., Busk, L., Kronevi, T., Nordgren, I., and Ahlborg, U. G., 1991. Relative liver tumour promoting activity and toxicity of some polychlorinated dibenzo-p-dioxin- and dibenzofuran-congeners in female Sprague-Dawley rats, Pharmacol. Toxicol 69 (1991), pp. 450–458, [INFOTRIEVE][CSA].
  • Walker, N. J., Crockett, P., Nyska, A., Brix, A., Jokinen, M. P., Sells, D. M., Hailey, J. R., Easterling, M., Haseman, J. K., Yin, M., Wyde, M. E., Bucher, J. R., and Portier, C. J., 2005. Dose-additive carcinogenicity of a defined mixture of “dioxin-like compounds.”, Environ. Health Perspect 113 (2005), pp. 43–48, [INFOTRIEVE][CSA].

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