Effects of PCB 126 on Primary Immune Organs and Thymocyte Apoptosis in Chicken Embryos

References

• Brown, T. L., Patil, S., Basnett, R. K., and Howe, P. H., 1998. Caspase inhibitor BD-fmk distinguishes transforming growth factor beta induced apoptosis from growth inhibition, Cell Growth Diff. 9 (1998), pp. 869–875, [CSA].
   PubMedGoogle Scholar
• Burchiel, S. W., Davis, D. P., Ray, S. D., Archuleta, M. M., Thilstead, J. P., and Corcoran, G. B., 1992. DMBA-induced cytotoxicity in lymphoid and nonlymphoid organs of B6C3F1 mice: relation of cell death to target cell intracellular calcium and DNA damage, Toxicol. Appl. Pharmacol. 113 (1992), pp. 126–132, [CROSSREF][CSA].
   PubMed Web of Science ®Google Scholar
• Burchiel, S. W., Davis, D. A., Ray, S. D., and Barton, S. L., 1993. DMBA induces programmed cell death (apoptosis) in A20.1 murine B cell lymphoma, Fundam. Appl. Toxicol. 21 (1993), pp. 120–124, [CROSSREF][CSA].
   PubMedGoogle Scholar
• Camacho, I. A., Nagarkatti, M., and Nagarkatti, P. S., 2002. . 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces Fas-dependent activation-induced cell death in superantigen-primed T cells, Arch. Toxicol. 76 (2002), pp. 570–580, [CROSSREF].
   PubMed Web of Science ®Google Scholar
• Cantrell, S. M., Lutz, L. H., Tillitt, D. E., and Hannink, M., 1996. Embryotoxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): The embryonic vasculature is a physiological target for TCDD-induced DNA damage and apoptotic cell death in medaka (Orizias latipes), Toxicol. Appl. Pharmacol. 141 (1996), pp. 23–34, [CSA].
   PubMed Web of Science ®Google Scholar
• Clark, D. A., Gauldie, J., Szewczuk, M. R., and Sweeney, G., 1981. Enhanced suppressor cell activity as a mechanism of immunosuppression by 2,3,7,8-tetrachlorodibenzo-p-dioxin, Proc. Soc. Exp. Biol. Med. 168 (1981), pp. 290–299, [CSA].
   PubMed Web of Science ®Google Scholar
• Clark, D. A., Sweeney, G., Safe, S., Hancock, E., Kilburn, D. G., and Gauldie, J., 1983. Cellular and genetic basis for suppression of cytotoxic T-cell generation by haloaromatic hydrocarbons, Immunopharmacology 6 (1983), pp. 143–153, [CROSSREF][CSA].
   PubMed Web of Science ®Google Scholar
• Comment, C. E., Blaylock, B. L., Germolec, D. R., Pollock, P. L., Kouchi, Y., Brown, H. W., Rosenthal, G. J., and Luster, M. I., 1992. Thymocyte injury after in vitro chemical exposure: Potential mechanisms for thymic atrophy, J. Pharmacol. Exp. Ther. 262 (1992), pp. 1267–1273, [CSA].
   PubMed Web of Science ®Google Scholar
• Compton, M., and Wickliffe, J. K., 1999. Multiparametric assessment of bursal lymphocyte, Apoptosis Dev. Comp. Immunol. 23 (1999), pp. 487–500, [CROSSREF][CSA].
   PubMed Web of Science ®Google Scholar
• Cooper, M. D., Chen, C. L., Bucy, R. P., and Thompson, C. B., 1991. Avian T cell ontogeny, Adv. Immunol. 50 (1991), pp. 87–117.
   PubMed Web of Science ®Google Scholar
• De Heer, C., De Waal, E. J., Schuurman, H. J., Vos, J. G., and Van Loveren, H., 1994. The intrathymic target cell for the thymotoxic action of 2,3,7,8-tetrachlorodibenzo-p-dioxin, Exp. Clin. Immunol. 11 (1994), pp. 86–93.
   PubMedGoogle Scholar
• De Waal, E. J., Schuurman, H. J., Loeber, J. G., Van Loveren, H., and Vos, J. G., 1992. Alterations in the cortical thymic epithelium of rats after in vivo exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): An (immuno) histological study, Toxicol. Appl. Pharmacol. 115 (1992), pp. 80–88, [CROSSREF][CSA].
   PubMed Web of Science ®Google Scholar
• Elferink, C. J., Ge, N.-L., and Levine, A., 2001. Maximal aryl hydrocarbon receptor activity depends on an interaction with the retinoblastoma protein. Mol., Pharmacol. 59 (2001), pp. 664–673.
   Web of Science ®Google Scholar
• Faleiro, L., Kobayashi, R., Fearnhead, H., and Lazebnik, Y., 1997. Multiple species of CPP32 and Mch2 are the major active caspases present in apoptotic cells, EMBO J. 16 (1997), pp. 2271–2281, [CROSSREF][CSA].
   PubMed Web of Science ®Google Scholar
• Fan, F., Wierda, D., and Rozman, K. K., 1996. Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on humoral and cell-mediated immunity in Sprague-Dawley rats, Toxicology 106 (1996), pp. 221–228, [CROSSREF][CSA].
   PubMed Web of Science ®Google Scholar
• Fox, L. L., and Grasman, K. A., 1999. Effects of PCB 126 on primary immune organ development in chicken embyros, J. Toxicol. Environ. Health A 58 (1999), pp. 233–244, [CROSSREF][CSA].
   PubMed Web of Science ®Google Scholar
• Ge, N.-L., and Elferink, C.J., 1998. A direct interaction between the aryl hydrocarbon receptor and retinoblastoma protein, J. Biol. Chem. 273 (1998), pp. 22708–22713, [CROSSREF].
   PubMed Web of Science ®Google Scholar
• Grasman, K. A., and Fox, G. A., 2001. Associations between altered immune function and organochlorine contamination in young Caspian terns (Sterna caspia) from Lake Huron, 1997–1999, Ecotoxicology 10 (2001), pp. 101–114, [CROSSREF].
   PubMed Web of Science ®Google Scholar
• Grasman, K. A., and Whitacre, L. L., 2001. Effects of PCB 126 on thymocyte surface marker expression and immune organ development in chicken embryos, J. Toxicol. Environ. Health A 62 (2001), pp. 191–206, [CROSSREF][CSA].
   PubMed Web of Science ®Google Scholar
• Grasman, K. A., Fox, G. A., Scanlon, P. F., and Ludwig, J. P., 1996. Organochlorine-associated immunosuppression in prefledling Caspian terns and Herring gulls for the Great Lakes: An ecoepidemiological study, Environ. Health Perspect 104 (1996), pp. 829–842, [CSA].
   PubMed Web of Science ®Google Scholar
• Gupta, S., and Cohen, J. J., 1996. Mechanisms of lymphocyte activation and immune regulation VI. New York: Plenum Press; 1996. pp. 191–201.
   Google Scholar
• Hardin, J. A., Hinoshita, F., and Sherr, D. H., 1992. Mechanisms by which benzo[a]pyrene, an environmental carcinogen, suppresses B cell lymphopoiesis, Toxicol. Appl. Pharmacol. 117 (1992), pp. 155–164, [CROSSREF][CSA].
   PubMed Web of Science ®Google Scholar
• Heimler, I., Rawlins, R. G., Owen, H., and Hutz, R. J., 1998. Dioxin perturbs, in a dose- and time-dependent fashion, steroid secretion and induces apoptosis of human luteinized granulose cells, Endocrinology 39 (1998), pp. 4373–4379, [CROSSREF].
   Google Scholar
• Hinsdill, R. D., Couch, D. L., and Speirs, R. S., 1980. Immunosuppression in mice induced by dioxin (TCDD) in feed, J. Environ. Pathol. Toxicol. 4 (1980), pp. 401–425.
   PubMed Web of Science ®Google Scholar
• Holladay, S., and Luster, M., 1994. "Developmental immunotoxicology". In: C. Kimmel, , and Buckejam, J., eds. Developmental toxicology. New York: Raven Press; 1994. pp. 93–118.
   Google Scholar
• Holladay, S., Lindstrom, P., Blaylock, B., Comment, C., Germolec, D., Heindell, J., and Luster, M., 1991. Perinatal thymocyte antigen expression and postnatal immune development altered by gestational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), Teratology 44 (1991), pp. 385–393.
   PubMedGoogle Scholar
• Holladay, S. D., Smith, S. A., Besteman, E. G., Deyab, A. S., Gogal, R. M., Hrubec, T., Robertson, J. L., and Ahmed, S. A., 1998. Benzo[a]pyrene-induced hypocellularity of pronephros in tilipia (Oreochromis niloticus) is accompanied by alterations in stromaland parenchymal cells and by enhanced immune cell apoptosis, Vet. Immunol. Immunopathol 64 (1998), pp. 69–82, [CROSSREF][CSA].
   PubMed Web of Science ®Google Scholar
• Hollander, M., and Wolfe, D. A., 1973. Nonparametric statistical methods. New York: John Wiley and Sons; 1973.
   Google Scholar
• Kamath, A. B., Xu, H., Nagarkatti, P. S., and Nagarkatti, M., 1997. Evidence for the induction of apoptosis in thymocytes by 2,3,7,8-tetrachlorodibenzo-p-dioxinin vivo, Toxicol. Appl. Pharmacol. 142 (1997), pp. 367–377, [CROSSREF][CSA].
   PubMed Web of Science ®Google Scholar
• Kamath, A. B., Nagarkatti, P. S., and Nagarkatti, M., 1998. Characteristics of phenotypic alterations induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin on thymocytes in vivo and its effects on apoptosis, Toxicol. Appl. Pharmacol. 150 (1998), pp. 117–124, [CROSSREF][CSA].
   PubMed Web of Science ®Google Scholar
• The influence of environmental contaminants on immune organ atrophy and thymocyte apoptosis in herring gull embryos from the Great Lakes. 2003, MS thesis, Wright State University, Dayton, OH..
   Google Scholar
• Kennedy, S. W., Lorenzen, A., and Jones, S. P., 1994. Sensitivity of various primary avian hepatocyte cell cultures to cytochrome P4501A induction by TCDD, TCDF, and PCBs, Organohalogen Compounds 21 (1994), pp. 475–480, .
   Google Scholar
• Kerkvliet, N. I., 1995. Immunological effects of chlorinated dibenzo-p-dioxins, Environ. Health Perspect 103 (1995), pp. 47–53.
   PubMed Web of Science ®Google Scholar
• Kerkvliet, N. I., 2002. Recent advances in understanding the mechanisms of TCDD immunotoxicity, Int. Immunolpharmacol. 2 (2002), pp. 277–291, [CROSSREF].
   Google Scholar
• Kolluri, S. K., Weiss, C., Koff, A., and Gottlicher, M., 1999. p27(Kip1) induction and inhibition of proliferation by the intracellular Ah receptor in developing thymus and hepatoma cells, Genes Dev. 13 (1999), pp. 1742–53.
   PubMed Web of Science ®Google Scholar
• Lundberg, K., 1991. Dexamethasone and 2,3,7,8-tetrachlorodibenzo-p-dioxin can induce thymic atrophy by different mechanisms in mice, Biochem. Biophys. Res. Commun. 178 (1991), pp. 16–23, [CROSSREF][CSA].
   PubMed Web of Science ®Google Scholar
• Lundberg, K., Gronvik, K. O., Goldschmidt, T. J., Klareskog, L., and Dencker, L., 1990. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) alters intrathymic T-cell development in mice, Chem. Biol. Interact 74 (1990), pp. 179–193, [CROSSREF].
   PubMed Web of Science ®Google Scholar
• McConkey, D. J., Hartzell, P., Duddy, S. K., Hakansson, H., and Orrenius, S., 1988. 2,3,7,8-Tetrachlorodibenzo-p-dioxin kills immature thymocytes by Ca2+-mediated endonuclease activation, Science 242 (1988), pp. 256–259.
   PubMed Web of Science ®Google Scholar
• Mignotte, B., and Vayssiere, J., 1998. Mitochondria and apoptosis, Eur. J. Biochem 252 (1998), pp. 1–15, [CROSSREF].
   PubMedGoogle Scholar
• Nagarkatti, P., Sweeney, G., Gauldie, J., and Clark, D., 1984. Sensitivity to suppression of cytotoxic T cell generation by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is dependent on the Ah genotype of the murine host, Toxicol. Appl. Pharmacol. 72 (1984), pp. 169–176, [CROSSREF][CSA].
   PubMed Web of Science ®Google Scholar
• Nicoletti, I., Migliorati, G., Pagliacci, M. C., Grignani, F., and Riccardi, C., 1991. A rapid and simple method for measuring thymocyte apoptosis by PI staining and flow cytometry, J. Immun. Meth. 139 (1991), pp. 271–279, [CROSSREF].
   PubMed Web of Science ®Google Scholar
• Nikolaidis, E., Brunström, B., and Dencker, L., 1988a. Effects of TCDD and its congeners 3,3′,4,4′ tetrachloroazoxybenzene and 3,3′,4,4′-tetrachlorobiphenyl on lymphoid development in thethymus of avian embryos, Pharmacol. Toxicol. 63 (1988a), pp. 333–336.
   PubMedGoogle Scholar
• Nikolaidis, E., Brunström, B., and Dencker, L., 1988b. Effects of the TCDD congeners 3,3′,′4,4′-tetra-chlorobiphenyl and 3,3′,4,4′-tetrachloroazoxybenzene on lymphoid development in the bursa of Fabricius of the chick embryo, Toxicol. Appl. Pharmacol. 92 (1988b), pp. 315–323, [CROSSREF][CSA].
   PubMed Web of Science ®Google Scholar
• Park, J.-H., and Lee, W.-W., 2002. Up-regulated expression of genes encoding Hrk and IL-3R beta subunit by TCDD in vivo and in vitro, Toxicol. Lett. 129 (2002), pp. 1–11, [CROSSREF][CSA].
   PubMed Web of Science ®Google Scholar
• Pekarik, C., Weseloh, D. V., Barrett, G. C., Simon, M., Bishop, C. A., and Pettit, K. E., 1998. An atlas of contamination in eggs of fish-eating colonial brids of the Great Lakes (1993–1997), Tech. Rep. Series 322. vol. I (1998), Toronto: Canadian Wildlife Service, Ontario Region[CSA].
   Google Scholar
• Piechotta, G., Lacorn, M., Lang, T., Kammann, U., Simat, T., Jenke, H., and Steinhart, H., 1999. Apoptosis in dab (Limanda limanda) as new biomarker for anthropogenic stress, Ecotoxicol. Environ. Safety 42 (1999), pp. 50–56, [CROSSREF][CSA].
   PubMed Web of Science ®Google Scholar
• Poland, A., and Knutson, J., 1982. 2,3,7,8-Tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: Examination of the mechanism of toxicity, Annu. Rev. Pharmacol. Toxicol. 22 (1982), pp. 517–554, [CROSSREF].
   PubMed Web of Science ®Google Scholar
• Pryputniewicz, S. J., Nagarkatti, M., and Nagarkatti, P. S., 1998. Differential induction of apoptosis in activated and resting T cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and its repercussion on T cell responsiveness, Toxicology 129 (1998), pp. 211–226, [CROSSREF][CSA].
   PubMed Web of Science ®Google Scholar
• Rhile, M. J., Nagarkatti, M., and Nagarkatti, P. S., 1996. Role of Fas apoptosis and MHC genes in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced immunotoxicity of T cells, Toxicology 110 (1996), pp. 153–167, [CROSSREF][CSA].
   PubMed Web of Science ®Google Scholar
• Silverstone, A., Frazier, D., Fiore, N., Soults, J., and Gasiewicz, T., 1994. Dexamethasone, β-estradiol, and 2,3,7,8-tetrachlorodibenzo-p-dioxin elicits thymic atrophy through different cellular targets, Toxicol. Appl. Pharmacol. 126 (1994), pp. 248–259, [CROSSREF][CSA].
   PubMed Web of Science ®Google Scholar
• Smialowicz, R., Andrews, J., Riddle, M., Rogers, R., Luebke, R., and Copeland, C., 1989. Evaluation of the immunotoxicity of low level PCB exposure in the rat, Toxicology 56 (1989), pp. 197–211, [CROSSREF][CSA].
   PubMed Web of Science ®Google Scholar
• Staples, J. E., Fiore, N. C., Frazier, D. E., Gasiewicz, T. A., and Silverstone, A. E., 1998. Overexpression of the anti-apoptotic oncogene, bcl-2, in the thymus does not prevent thymic atrophy induced by estradiol or 2,3,7,8-tetrachlorodibenzo-p-dioxin., Toxicol. Appl. Pharmacol. 151 (1998), pp. 200–210, [CROSSREF][CSA].
   PubMed Web of Science ®Google Scholar
• Surh, C. D., and Sprent, J., 1994. T cell apoptosis detected in situ during positive and negative selection in the thymus, Nature 372 (1994), pp. 100–103, [CROSSREF].
   PubMed Web of Science ®Google Scholar
• Telford, W. G., King, L. E., and Fraker, P. J., 1991. Evaluation of glucocorticoid-induced DNA fragments in mouse thymocytes by flow cytometry, Cell Prolif. 24 (1991), pp. 447–457.
   PubMed Web of Science ®Google Scholar
• Telford, W. G., King, L. E., and Fraker, P. J., 1992. Flow cytometric analysis of apoptosis: A review, Appl. Fluor. Technol. 4 (1992), pp. 12–22, .
   Google Scholar
• Tharappel, J. C., Lee, E. Y., Robertson, L. W., Spear, B. T., and Glauert, H. P., 2002. Regulation of cell proliferation, apoptosis, and transcription factor activities during the promotion of liver carcinogenesis by polychlorinated biphenyls, Toxicol. Appl. Pharmacol. 179 (2002), pp. 172–184, [CSA].
   PubMed Web of Science ®Google Scholar
• Thornberry, N. A., and Lazebnik, Y., 1998. Caspases: Enemies within, Science 281 (1998), pp. 1312–1315, [CROSSREF].
   PubMed Web of Science ®Google Scholar
• Van den Berg, M., Birnbaum, L., Bosveld, A. T. C., Brunström, B., Cook, P., Feeley, M., Giesy, J. P., Hanberg, A., Hasegawa, R., Kennedy, S. W., Kubiak, T., Larsen, J. C., van Leeuwen, F. X. R., Liem, A. K. D., Nolt., C., Peterson, R. E., Poellinger, L., Safe, S., Schrenk, D., Tillitt, D., Tysklind, M., Younes, M., Wærn, F., and Zacharewski, T., 1998. Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife, Environ. Health Perspect 106 (1998), pp. 775–792, [CSA].
   PubMed Web of Science ®Google Scholar
• Yoo, B. S., Jung, K. H., Hana, S. B., and Kim, H. M., 1997. Apoptosis-mediated immunotoxicity of polychlorinated biphenyls in murine splenocytes, Toxicol. Lett. 91 (1997), pp. 83–89, [CROSSREF][CSA].
   PubMed Web of Science ®Google Scholar
• Zamai, L., Falcieri, E., Zanli, G., Cataldi, A., and Vitale, M., 1993. Optimal detection of apoptosis by flow cytometry depends on cell morphology, Cytometry 14 (1993), pp. 891–897.
   PubMedGoogle Scholar
• Zeytun, A., McKallip, R. J., Fisher, M., Camacho, I., Nagarkatti, M., and Nagarkatti, P., 2002. Analysis of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced gene expression profile in vivo using pathway-specific cDNA arrays, Toxicology 178 (2002), pp. 241–260, [CROSSREF][CSA].
   PubMed Web of Science ®Google Scholar