405
Views
59
CrossRef citations to date
0
Altmetric
Original Articles

Suppression of Humoral Immunity Following Exposure to the Perfluorinated Insecticide Sulfluramid

, , , , , & show all
Pages 1130-1141 | Received 06 Feb 2006, Accepted 08 Sep 2006, Published online: 07 Jun 2007

REFERENCES

  • Biegel , L. B. , Hurtt , M. E. , Frame , S. R. , O'Connor , J. C. and Cook , J. C. 2001 . Mechanisms of extrahepatic tumor induction by peroxisome proliferators in male CD rats . Toxicol. Sci. , 60 : 44 – 55 .
  • Belisle , J. FC-143 analysis of serum samples from rats from 28-day studies , Available on U.S. EPA Public Docket AR-226 (No. 226–0442) . 1978
  • Borges , T. , Robertson , L. W. , Peterson , R. E and Glauert , H. P. 1992 . Dose-related effects of perfluorodecanoic acid on growth, feed intake and hepatic peroxisomal beta-oxidation . Arch. Toxicol. , 66 : 18 – 22 .
  • Bryant , J. , Day , R. , Whiteside , T. L. and Herberman , R. B. 1992 . Calculation of lytic units for the expression of cell-mediated cytotoxicity . J. Immunol. Methods , 146 : 91 – 103 .
  • Burris , J. M. , Lundberg , J. K. , Olsen , G. W. , Simpson , C. and Mandel , J. H. " Determination of serum half-lives of several fluorochemicals ." Interim Report #2. Available on USEPA Public docket AR-226 (No. 226–1086) . 2002
  • Chaffin , C. L. , Peterson , R. E. and Hutz , R. J. 1996 . In utero and lactational exposure of female Holtzman rats to 2,3,7,8-tetrachlorodibenzo-p-dioxin: Modulation of the estrogen signal . Biol. Reprod. , 55 : 62 – 67 .
  • Cook , J. C. , Murray , S. M. , Frame , S. R. and Hurtt , M. E. 1992 . Induction of Leydig cell adenomas by ammonium perfluorooctanoate; A possible endocrine-related mechanism . Toxicol. Appl. Pharmacol. , 113 : 209 – 217 .
  • Cunningham , A. J. and Szenberg , A. 1968 . Further improvements in the plaque forming technique for detecting single antibody forming cells . Immmunology , 14 : 599 – 601 .
  • Dean , J. H. , ed. 1994 . Immunotoxicology and immunopharmacology: Target organ toxicology series , 2nd , Boca Raton, FL : CRC Press .
  • Dickerson , R. , Keller , L. H. and Safe , S. 1995 . Alkyl polychlorinated dibenzofurans and related compounds as antiestrogens in the female rat uterus: Structure–activity studies . Toxicol. Appl. Pharmacol. , 135 : 287 – 298 .
  • Duke , S. S. , Schook , L.B. and Holsapple , M. P. 1985 . Effects of N-nitrodimethylamine on tumor susceptibility . J. Leukocyte Biol. , 37 : 383 – 394 .
  • Evans , J. S. , Varney , R. F. and Koch , F. C. 1941 . The mouse uterine wet weight method for the assay of estrogens . Endocrinology , 28 : 747 – 752 .
  • Galand , R. , Mairesse , N. , Roorijck , J. and Flandroy , L. 1983 . Differential blockade of estrogen-induced uterine responses by the antiestrogen nafoxidine . J. Steroid Biochem. , 19 : 1259 – 1263 .
  • Giesy , J. P. and Kannan , K. 2001 . Global distribution of perfluorooctane sulfonate in wildlife . Environ. Sci. Technol. , 35 : 1339 – 1342 .
  • Giesy , J. P. and Kannan , K. 2002 . Perfluorochemical surfactants in the environment . Environ. Sci. Technol. , 36 : 146A – 152A .
  • Grossman , M. R. , Mispagel , M. E. and Bowen , J. M. 1992 . Distribution and tissue elimination in rats during and after prolonged dietary exposure to a highly fluorinated sulfonamide pesticide . J. Agric. Food Chem. , 40 : 2505 – 2509 .
  • Hansen , K. J. , Clemen , L. A. , Ellefson , M. E. and Johnson , H. O. 2001 . Compound-specific, quantitative characterization of organic fluorochemicals in biological matrices . Environ. Sci. Technol. , 35 : 766 – 770 .
  • Hany , J. , Lilienthal , H. , Sarasin , A. , Roth-Harer , A. , Fastabend , A. , Dunemannm , L. , Lichtensteiger , W. and Winneke , G. 1999 . Developmental exposure of rats to a reconstituted PCB mixture or aroclor 1254: Effects on organ weights, aromatase activity, sex hormone levels, and sweet preference behavior . Toxicol. Appl. Pharmacol. , 158 : 231 – 243 .
  • Harper , N. , Howie , L. , Connor , K. , Dickerson , R. and Safe , S. 1993 . Immunosuppressive effects of highly chlorinated biphenyls and diphenyl ethers on T-cell dependent and independent antigens in mice . Toxicology , 85 : 123 – 135 .
  • Houde , M. , Wells , R. S. , Fair , P. A. , Bossart , G. D. , Hohn , A. A. , Rowles , T. K. , Sweeney , J. C. , Solomon , K. R. and Muir , D. C. 2005 . Polyfluoroalkyl compounds in free-ranging bottlenose dolphins (Tursiops truncatus) from the Gulf of Mexico and the Atlantic Ocean . Environ. Sci. Technol. , 39 : 6591 – 6598 .
  • Holsapple , M. P. , White , K. L. , McCay , J. A. , Bradley , S. G. and Munson , A. E. 1988 . An immunotoxicological evaluation of 4,4′-thiobis-(6-t-butyl-m-cresol) in female B6C3F1 mice. 2. Humoral and cell-mediated immunity, macrophage function, and host resistance . Fundam. Appl. Toxicol. , 10 : 701 – 716 .
  • Jerne , N. K. and Nordin , A. A. 1963 . Plaque formation in agar by single antibody producing cells . Science , 140 : 405
  • Johnson , J. D. , Gibson , S. J. and Ober , R. E. 1984 . Cholestyramine-enhanced fecal elimination of carbon-14 in rats after administration of ammonium [14C]perfluorooctanoate or potassium [14C]perfuorooctanesulfonate . Fundam. Appl. Toxicol. , 4 : 972 – 976 .
  • Kannan , K. , Frankson , J. C. , Bowerman , W. W. , Hansen , K. J. , Jones , P. D. and Giesy , J. P. 2001a . Perfluorooctane sulfonate in fish-eating water birds including bald eagles and albatrosses . Environ. Sci. Technol. , 35 : 3065 – 3070 .
  • Kannan , K. , Koistinen , J. , Beckmen , K. , Evans , T. , Gorzelany , J. F. , Hansen , K. J. , Jones , P. D. , Helle , E. , Nyman , M. and Giesy , J. P. 2001b . Accumulation of perfluorooctane sulfonate in marine mammals . Environ. Sci. Technol. , 35 : 1593 – 1598 .
  • Kannan , K. , Choi , J. , Iseki , N. , Senthilkumar , K. , Kim , D. H. , Masunaga , S. and Giesy , J. P. 2002a . Concentrations of perfluorinated acids in livers of birds from Japan and Korea . Chemosphere , 49 : 225 – 231 .
  • Kannan , K. , Corsolini , S. , Falandysz , J. , Oehme , F. , Focardi , S. and Giesy , J. P. 2002b . Perfluorooctanesulfonate and related fluorinated hydrocarbons in marine mammals, fishes, and birds from coasts of the Baltic and the Mediterranean Seas . Environ. Sci. Technol. , 36 : 3210 – 3216 .
  • Kannan , K. , Newstead , J. , Halbrook , Richard , S. and Giesy , J. P. 2002c . Perfluorooctanesulfonate and related fluorinated hydrocarbons in mink and river otters from the United States . Environ. Sci. Technol. , 36 : 2566 – 2571 .
  • Kanno , J. , Onyon , L. , Haseman , J. , Fenner-Crisp , P. , Ashby , J. and Owens , W. 2001 . The OECD program to validate the rat uterotrophic bioassay to screen compounds for in vivo estrogenic responses: Phase 1 . Environ. Health Perspect. , 109 : 785 – 794 .
  • Keller , J. M. , Kannan , K. , Taniyasu , S. , Yamashita , N. , Day , R. D. , Arendt , M. D. , Segars , A. L. and Kucklick , J. R. 2005 . Perfluorinated compounds in the plasma of loggerhead and Kemp's ridley sea turtles from the southeastern coast of the United States . Environ. Sci. Technol. , 39 : 9101 – 9108 .
  • Kennedy , G. L. 1985 . Dermal toxicity of ammonium perfluorooctanoate . Toxicol. Appl. Pharmacol. , 81 : 348 – 355 .
  • Kennedy , G. L. 1987 . Increase in mouse liver weight following feeding of ammonium perfluorooctanoate and related fluorochemicals . Toxicol. Lett. , 39 : 295 – 300 .
  • Liem , D. December 3 1991 . Study type: Subchronic oral toxicity study guideline 82–1; Test animal CDBR Sprague-Dawley rats; MRID No. 417994-05 (Data Evaluation Review) , December 3 , Washington, DC : U.S. Environmental Protection Agency .
  • Liem , D. July 23 1992 . Study type: 21-Day dermal toxicity—Rabbits guideline 82–1; Test animal CDBR Sprague-Dawley rats; MRID No. 417994-05 (Data Evaluation Review) , July 23 , Washington, DC : Environmental Protection Agency .
  • Liu , R. C. , Hurtt , M. E. , Cook , J. C. and Biegel , L. B. 1996a . Effect of the peroxisome proliferator, ammonium perfluorooctanoate (C8) on hepatic aromatase activity in adult male Crl;CD BR (CD) rats . Fundam. Appl. Toxicol. , 30 : 220 – 228 .
  • Liu , R. C. , Hahn , C. and Hurtt , M. E. 1996b . The direct effect of hepatic peroxisome proliferators on rat Leydig cell function in vitro . Fundam. Appl. Toxicol. , 30 : 102 – 108 .
  • Luster , M. I. , Munson , A. E. , Thomas , P. T. , Holsapple , M. P. , Fenters , J. D. , White , K. L. Jr. , Lauer , L. D. , Germolec , D. R. , Rosenthal , G. J. and Dean , J. H. 1998 . Development of a testing battery to assess chemical-induced immunotoxicity: National Toxicology Program's guidelines for immunotoxicity evaluation in mice . Fundam. Appl. Toxicol. , 10 : 2 – 19 .
  • Luster , M. I. , Portier , C. , Pait , D. G. , White , K. L. Jr. , Gennings , C. , Munson , A .E. and Rosenthal , G. J. 1992 . Risk assessment in immunotoxicology. I. Sensitivity and predictability of immune tests . Fundam. Appl. Toxicol. , 18 : 200 – 210 .
  • Manning , R. O. , Bruckner , J. V. , Mispagel , M. E. and Bowen , J. M. 1991 . Metabolism and disposition of sulfluramid, a unique polyfluorinated insecticide, in the rat . Drug Metab. Dispos. , 19 : 205 – 211 .
  • Markey , C. M. , Michaelson , C. L. , Veson , E. C. , Sonnenschein , C. and Soto , A. M. 2001 . The mouse uterotrophic assay: a reevaluation of its validity in assessing the estrogenicity of bisphenol A . Environ. Health Perspect. , 109 : 55 – 60 .
  • McBlain , W. A. , Lewin , V. and Wolfe , F. H. 1976 . Differing estrogenic activities for the enantiomers of o, p'-DDT in immature female rats . Can. J. Physiol. Pharmacol. , 54 : 629 – 632 .
  • Metrick , M. and Marias , A. J. 28-Day oral toxicity study with FC-143 in albino rats , Available on U.S.EPA Public Docket AR-226 (No. 226–0445) . 1977
  • Moody , C. A. and Field , J. A. 2000 . Perfluorinated surfactants and the environmental implications of their use in fire-fighting foams . Environ. Sci. Technol. , 34 : 3864 – 3870 .
  • Nelson , D. L. , Frazier , D. E. Jr. , Ericson , J. E. , Tarr , M. J. and Mathes , L. E. 1992 . The effects of perfluorodecanoic acid (PDFA) on humoral, cellular, and innate immunity in Fisher 344 rats . Immunopharmacol. Immunotoxicol. , 14 : 925 – 938 .
  • Okazaki , K. , Imazawa , T. , Nakamura , H. , Furukawa , F. , Nishikawa , A. and Hirose , M. 2002 . A repeated 28-day oral dose toxicity study of 17α-methyltestosterone in rats, based on the “enhanced OECD test guideline 407” for screening the endocrine-disrupting chemicals . Arch. Toxicol. , 75 : 635 – 642 .
  • Olsen , G. W. , Burris , J. M. , Mandel , J. H. and Zobel , L. R. 1999 . Serum perfluorooctane sulfonate and hepatic and lipid clinical chemistry tests in fluorochemical production employees . J. Occup. Environ. Med. , 41 : 799 – 806 .
  • Olsen , G. W. , Burris , J. M. , Burlew , M. M. and Mandel , J. H. 2003a . Epidemiologic assessment of worker serum perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA) concentrations and medical surveillance examinations . J. Occup. Environ. Med. , 45 : 260 – 270 .
  • Olsen , G. W. , Hansen , K. J. , Stevenson , L. A. , Burris , J. M. and Mandel , J. H. 2003b . Human donor liver and serum concentrations of perfluorooctanesulfonate and other perfluorochemicals . Environ. Sci. Technol. , 37 : 888 – 891 .
  • Owens , J. W. and Ashby , J. 2002 . Critical review and evaluation of the uterotrophic bioassay for the identification of possible estrogen agonists and antagonists: In support of the validation of the OECD uterotrophic protocols for the laboratory rodent . Crit. Rev. Toxicol. , 32 : 445 – 520 .
  • Padilla-Banks , E. , Jefferson , W. N. and Newbold , R. R. 2001 . The immature mouse is a suitable model for detection of estrogenicity in the uteroscopic bioassay . Environ. Health Perspect. , 109 : 821 – 826 .
  • Pastoor , T. P. , Lee , K. P. , Perri , M. A. and Gillies , P. J. 1987 . Biochemical and morphological studies of ammonium perfluorooctanoate-induced hepatomegaly and peroxisome proliferation . Exp. Mol. Pathol. , 47 : 98 – 109 .
  • Peden-Adams , M. M. , Stuckey , J. , EuDaly , J. and Keil , D. E. 2006 . Oral exposure to PFOS for 28 days suppresses immunological function in B6C3F1 mice. , 90 ( S-1 ) : 53 Abstract 256 Toxicologist
  • Puri , C. P. , Mac Kenzie , L. W. , Garfield , R. E. and Wiest , W. G. 1984 . Uterotropic action of indomethacin on the rat uterus . Biol. Reprod. , 30 : 1027 – 1038 .
  • Schnellman , R. G. 1990 . The cellular effects of a unique pesticide sulfluramid (n-ethylperfluorooctane sulphonamide) on rabbit renal proximal tubules . Toxicol. In Vitro. , 4 : 71 – 74 .
  • Schnellmann , R. G. and Manning , R. O. 1990 . Perfluorooctane sulfonamide: A structurally novel uncoupler of oxidative phosphorylation . Biochem. Biophys. Acta. , 1016 : 344 – 348 .
  • Seacat , A. M. , Thomford , P. J. , Hansen , K. J. , Clemen , L. A. , Eldridge , S. R. , Elcombe , C. R. and Butenhoff , J. L. 2003 . Sub-chronic dietary toxicity of postassium perfluorooctanesulfonate in rats . Toxicology , 183 : 117 – 131 .
  • Seacat , A. M. and Luebker , D. J. Toxicokinetic study of perflurooctane sulfonamide (PFOSA;T-7132.2) in rats , Available on U.S. EPA Public Docket AR-226 (No. 226–0993) . 2000
  • Shipley , J. M,. , Hurst , C. H. , Tanaka , S. S. , DeRoos , F. L. , Butenhoff , J. L. , Seacat , A. M. and Waxman , D. J. 2004 . Trans-activation of PPARalpha and induction of PPAR alpha target genes by perfluorooctane-based chemicals . Toxicol. Sci. , 80 ( 1 ) : 151 – 160 .
  • Taylor , L. March 21 1990 . Review of studies required in the conditional registration of sulfluramid—Dermal sensitization study in guinea pigs and rat primary hepatocyte unscheduled DNA synthesis assay , March 21 , Washington, DC : U. S. Environmental Protection Agency . MRID 412510-01 (Data Evaluation Review)
  • U.S. Environmental Protection Agency . 1984 . Pesticide assessment guidelines, subdivision F: hazard evaluation, human and domestic animals , revised PB86 – 108958 .
  • U.S. Environmental Protection Agency . 1989 . Pesticide fact sheet. Sulfluramid (GX-071)
  • Vial , T. , Nicolas , B. and Descotes , J. 1996 . Clinical immunotoxicity of pesticides . J. Toxicol. Environ. Health A. , 48 : 215 – 229 .
  • Wetzel, L. T. 1983. Rat teratology study, T-3351, final report. Hazelton Laboratories America, Inc. Project 154–160. December 19, 1983 (8EHQ-0399-374). Available on U.S. EPA Public Docket AR-226 (No. 226–0014).
  • Yang , Q. , Xie , Y. and Depierre , J. W. 2000 . Effects of peroxisome proliferators on the thymus and spleen of mice . Clin. Exp. Immunol. , 122 : 219 – 266 .
  • Yang , Q. , Xie , Y. , Eriksson , A. M. , Nelson , B. D. and DePierre , J. W. 2001 . Further evidence for the involvement of inhibition of cell proliferation and development in thymic and splenic atrophy induced by the peroxisome proliferator perfluoroctanoic acid in mice . Biochem. Pharmacol. , 62 : 1133 – 1140 .
  • Yang , Q. , Abedi-Valugerdi , M. , Xie , Y. , Zhao , X. , Möller , G. , Nelson , B. D. and Depierre , J. W. 2002 . Potent suppression of the adaptive immune response in mice upon dietary exposure to the potent peroxisome proliferator, perfluorooctanoic acid . Int. Immunopharmacol. , 2 : 389 – 397 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.