Effect of Cold Storage on In Vitro Human Skin Absorption of Six ¹⁴C-Radiolabeled Environmental Contaminants: Benzo[a]Pyrene, Ethylene Glycol, Methyl Parathion, Naphthalene, Nonyl Phenol, and Toluene

REFERENCES

• Babu , R. J. , Kanikkannan , N. , Kikwai , L. , Ortega , C. , Andega , S. , Ball , K. , Yim , S. and Singh , M. 2003 . The influence of various methods of cold storage of skin on the permeation of melatonin and nimesulide . J. Controlled Release , 86 : 49 – 57 .
   PubMed Web of Science ®Google Scholar
• Baxter , C. , Aggarwal , S. and Diller , K. R. 1985 . Cryopreservation of skin: A review . Transplant. Proc. , 17 ( Suppl. 4 ) : 112 – 120 .
   PubMedGoogle Scholar
• Ben-Bassat , H. , Chaouat , M. , Segal , N. , Zumai , E. , Wexler , M. R. and Eldad , A. 2001 . How long can cryopreserved skin be stored to maintain adequate graft performance? . Burns , 27 : 425 – 431 .
   PubMed Web of Science ®Google Scholar
• Bosman , I. J. , Ensing , K. and de Zeeuw , R. A. 1998 . Standardization procedure for the in vitro skin permeation of anticholinergics . Int. J. Pharm. , 169 : 65 – 73 .
   Web of Science ®Google Scholar
• Bronaugh , R. L. , Stewart , R. F. and Simon , M. 1986 . Methods for in vitro percutaneous absorption studies. VII: Use of excised human skin . J. Pharm. Sci. , 75 : 1094 – 1097 .
   PubMed Web of Science ®Google Scholar
• Chu , I. 1995 . Alternative methods to animal testing: A Canadian Health Protection Branch perspective . ATLA , 23 : 257 – 261 .
   Google Scholar
• Collier , S. W. , Sheikh , N. M. , Sakr , A. , Lichtin , J. L. , Stewart , R. F. and Bronaugh , R. L. 1989 . Maintenance of skin viability during in vitro percutaneous absorption/metabolism studies . Toxicol. Appl. Pharmacol. , 99 : 522 – 533 .
   PubMed Web of Science ®Google Scholar
• Dayan , N. 2005 . Pathways for skin penetration . Cosmet. Toiletries , 120 : 67 – 74 .
   Google Scholar
• Feldmann , R. J. and Maibach , H. I. 1970 . Absorption of some organic compounds through the skin in man . J. Invest. Dermatol. , 54 : 399 – 404 .
   PubMed Web of Science ®Google Scholar
• Feldmann , R. J. and Maibach , H. I. 1974 . Percutaneous penetration of some pesticides and herbicides in man . Toxicol. Appl. Pharmacol. , 28 : 126 – 132 .
   PubMed Web of Science ®Google Scholar
• Franklin , C. A. , Somers , D. A. and Chu , I. 1989 . Use of percutaneous absorption data in risk assessment . J. Am. Coll. Toxicol. , 8 : 815 – 827 .
   Google Scholar
• Hadzija , B. W. , Ruddy , S. B. and Ballenger , E. S. 1992 . Effect of freezing on iontophoretic transport through hairless rat skin . J. Pharm. Pharmacol. , 44 : 387 – 390 .
   PubMed Web of Science ®Google Scholar
• Harrison , S. M. , Barry , B. W. and Dugard , P. H. 1984 . Effects of freezing on human skin permeability . J. Pharm. Pharmacol. , 36 : 261 – 262 .
   PubMed Web of Science ®Google Scholar
• Hawkins , G. S. Jr. and Reifenrath , W. G. 1984 . Development of an in vitro model for determining the fate of chemicals applied to skin . Fundam. Appl. Toxicol. , 4 : S133 – S144 .
   PubMedGoogle Scholar
• Hoang, K. T. 1992. Dermal exposure assessment: Principles and applications. U.S. Environmental Protection Agency, Exposure Assessment Group. Washington, DC: Office of Health and Environmental Assessment. http://cfpub.epa.gov/ncea/cfm/recordisplay.cfm?deid=12188 (Accessed: 23 January 2008 ).
   Google Scholar
• Holland , J. M. , Kao , J. Y. and Whitaker , M. J. 1984 . A multisample apparatus for kinetic evaluation of skin penetration in vitro: The influence of viability and metabolic status of the skin . Toxicol. Appl. Pharmacol. , 72 : 272 – 280 .
   PubMed Web of Science ®Google Scholar
• Kasting , G. B. and Bowman , L. A. 1990 . Electrical analysis of fresh, excised human skin: A comparison with frozen skin . Pharm. Res. , 7 : 1141 – 1146 .
   PubMed Web of Science ®Google Scholar
• Kemppainen , B. W. , Riley , R. T. , Pace , J. G. and Hoerr , F. J. 1986 . Effects of skin storage conditions and concentration of applied dose on [3H]T-2 toxin penetration through excised human and monkey skin . Food Chem. Toxicol. , 24 : 221 – 227 .
   PubMed Web of Science ®Google Scholar
• 2001 , Kwah, M. “ Toxicology of skin, Target Organ Toxicology Series ” . In In vitro viability assays , Edited by: Maibach , H. I. 513 – 529 . Boca Raton, FL : Taylor & Francis .
   Google Scholar
• May , S. R. and deClement , F. A. 1981 . Skin banking. Part III. Cadaveric allograft skin viability . J. Burn Care Rehab. , 2 : 128 – 141 .
   Google Scholar
• Menon , G. K. and Elias , P. M. 1997 . Morphologic basis for a pore-pathway in mammalian stratum corneum . Skin Pharmacol. , 10 : 235 – 246 .
   PubMedGoogle Scholar
• Mikhailov , I. N. 1976 . Changes in the ultrastructure on the human epidermis on freezing . Bull. Exp. Biol. Med. , 81 : 379 – 461 .
   Web of Science ®Google Scholar
• Moir , D. , Marwood , T. M. and Moody , R. P. 1994 . In vitro cutaneous metabolism of DDT in human and animal skins . Bull. Environ. Contam. Toxicol. , 52 : 474 – 478 .
   PubMed Web of Science ®Google Scholar
• Moody , R. P. , Akram , M. , Dickson , E. and Chu , I. 2007a . In vitro dermal absorption of methyl salicylate, ethyl parathion, and malathion: First responder safety . J. Toxicol. Environ. Health , A 70 : 985 – 999 .
   Web of Science ®Google Scholar
• Moody , R. P. , Joncas , J. , Richardson , M. and Chu , I. 2007b . Contaminated soils (I): In vitro dermal absorption of benzo[a]pyrene in human skin . J. Toxicol. Environ. Health , A 70 : 1858 – 1865 .
   Web of Science ®Google Scholar
• Moody , R. P. and MacPherson , H. 2003 . Determination of dermal absorption QSAR/QSPRs by brute force regression: Multiparameter model development with Molsuite 2000 . J. Toxicol Environ Health , A 66 : 1927 – 1942 .
   Web of Science ®Google Scholar
• Moody , R. P. and Martineau , P. A. 1990 . An automated in vitro dermal absorption procedure: I: Permeation of 14C-labelled N, N-diethyl-m-toluamide through human skin and effects of short-wave ultraviolet radiation on permeation . Toxicol. In Vitro , 4 : 193 – 199 .
   PubMed Web of Science ®Google Scholar
• Nakai , J. S. , Chu , I. , Li-Muller , A. and Aucoin , R. 1997 . Effect of environmental conditions on the penetration of benzene through human skin . J. Toxicol. Environ. Health , A 51 : 447 – 462 .
   PubMedGoogle Scholar
• Nakai , J. S. , Stathopulos , P. B. , Campbell , G. L. , Chu , I. , Li-Muller , A. and Aucoin , R. 1999 . Penetration of chloroform, trichloroethylene, and tetrachloroethylene through human skin . J. Toxicol. Environ. Health , A 58 : 157 – 170 .
   Google Scholar
• Ng , K. M. E. , Chu , I. , Bronaugh , R. L. , Franklin , C. A. and Somers , D. A. 1992 . Percutaneous absorption and metabolism of pyrene, benzo[a]pyrene, and di(2-ethylhexyl) phthalate: Comparison of in vitro and in vivo results in the hairless guinea pig . Toxicol. Appl. Pharmacol. , 115 : 216 – 223 .
   PubMed Web of Science ®Google Scholar
• Organization for Economic Cooperation and Cultural Development . Draft guidance document for the conduct of skin absorption studies . Environmental Health and Safety Publications, Environment Directorate series on testing and assessment No. 28 . 2000 . Paris: Organization for Economic Cooperation and Cultural Development.
   Google Scholar
• Organization for Economic Cooperation and Cultural Development . 2004 . Guideline for the testing of chemicals. Skin absorption: in vitro method 428 , Paris : Organization for Economic Cooperation and Development .
   Google Scholar
• Reifenrath , W. G. and Kemppainen , B. W. 1991 . “ Skin storage conditons ” . In In vitro percutaneous absorption: Principles, fundamentals, and applications , Edited by: Bronaugh , R. L. and Maibach , H. I. 115 – 127 . Boca Raton, FL : Taylor & Francis .
   Google Scholar
• Rosenquist , M. D. , Cram , A. E. and Kealey , G. P. 1988a . Short-term skin preservation at 4 degrees C: Skin storage configuration and tissue-to-volume medium ratio . J. Burn Care Rehab. , 9 : 52 – 54 .
   PubMedGoogle Scholar
• Rosenquist , M. D. , Cram , A. E. and Kealey , G. P. 1988b . Skin preservation at 4 degrees C: A species comparison . Cryobiology , 25 : 31 – 37 .
   PubMed Web of Science ®Google Scholar
• Ryan, J. 2006. General guide for cryogenically storing animal cell cultures. Technical bulletin. Corning Life Sciences. Sigma Cell Culture Manual 2005–2006, pp. 327–331. www.corning.com/Lifesciences/technical_information/techDocs/t_cryoanimalcc.pdf (Accessed: 14 January 2008 ).
   Google Scholar
• Sintov , A. C. and Botner , S. 2006 . Transdermal drug delivery using microencapsulation and aqueous systems: Influence of skin storage conditions on the in vitro permeability of diclofenac from aqueous vehicle systems . Int. J. Pharma. , 311 : 55 – 62 .
   PubMed Web of Science ®Google Scholar
• Shaikh , N. A. , Ademola , J. I. and Maibach , H. I. 1996 . Effects of freezing and azide treatment of in vitro human skin on the flux and metabolism of 8-methoxypsoralen . Skin Pharmacol , 9 : 274 – 280 .
   PubMedGoogle Scholar
• Schuhmaker-Wolz , U. , Kalberlah , F. , Oppl , R. and Van Hemmen , J. J. 2003 . A toolkit for dermal risk assessment: Toxicological approach for hazard characterization . Ann. Occup. Hyg. , 47 : 641 – 652 .
   PubMedGoogle Scholar
• Swarbrick , J. , Lee , G. and Brown , J. 1982 . Drug permeation through human skin: I. Effect of storage conditions of skin . J. Invest. Dermatol. , 78 : 63 – 66 .
   PubMed Web of Science ®Google Scholar
• Tezel , A. , Sens , A. and Mitragotri , S. 2002 . Incorporation of lipophilic pathways into the porous pathway model for describing skin permeabilization during low-frequency sonophoresis . J. Control. Release , 83 : 183 – 188 .
   PubMed Web of Science ®Google Scholar
• Tezel , A. , Sens , A. and Mitragotri , S. 2003 . Description of transdermal transport of hydrophilic solutes during low-frequency sonophoresis based on a modified porous pathway model . J. Pharm. Sci. , 92 : 381 – 393 .
   PubMed Web of Science ®Google Scholar
• U.S. Environmental Protection Agency. 1997. Dermal route. In Exposure factors handbook revised, Vol, 1 General factors, Chapter 6. Washington, DC: U.S. Environmental Protection Agency, National Center for Environmental Assessment www.epa.gov/ncea/efh (Accessed: 23 January 2008 ).
   Google Scholar
• Wang , T. F. , Kasting , G. B. and Nitschei , J. M. 2007 . Multiphase microscopic diffusion model for stratum corneum permeability. II. Estimation of physicochemical parameters, and application to a large permeability database . J. Pharm. Sci. , 96 : 3024 – 3051 .
   PubMed Web of Science ®Google Scholar
• Wester , R. C. , Christoffel , J. , Hartway , T. , Poblete , N. , Maibach , H. I. and Forsell , J. 1998 . Human cadaver skin viability for in vitro percutaneous absorption: Storage and detrimental effects of heat-separation and freezing . Pharm. Res. , 15 : 82 – 84 .
   PubMed Web of Science ®Google Scholar
• Yourick , J. J. , Koenig , M. L. , Yourick , D. L. and Bronaugh , R. L. 2004 . Fate of chemicals in skin after dermal application: Does the in vitro skin reservoir affect the estimate of systemic absorption? . Toxicol. Appl. Pharmacol. , 195 : 309 – 320 .
   PubMed Web of Science ®Google Scholar
• Zieger , M. A. J. , Tredget , E. E. , Sykes , B. D. and McGann , L. E. 1997 . Injury and protection in split-thickness skin after very rapid cooling and warming . Cryobiology , 35 : 53 – 69 .
   PubMed Web of Science ®Google Scholar