Transgenic Mice Expressing Cyan Fluorescent Protein as a Reporter Strain to Detect the Effects of Rotenone Toxicity on Retinal Ganglion Cells

REFERENCES

• Barnstable , C. J. , Akagawa , K. , Hofstein , R. and Horn , J. P. 1983 . Monoclonal antibodies that label discrete cell types in the mammalian nervous system . Cold Spring Harbor Symp. Quant. Biol. , 48 ( Pt 2 ) : 863 – 876 .
   Google Scholar
• Barnstable , C. J. and Drager , U. C. 1984 . Thy-1 antigen: A ganglion cell specific marker in rodent retina . Neuroscience , 11 : 847 – 855 .
   PubMed Web of Science ®Google Scholar
• Beal , M. F. 1998 . Mitochondrial dysfunction in neurodegenerative diseases . Biochim. Biophys. Acta , 1366 : 211 – 223 .
   PubMed Web of Science ®Google Scholar
• Beal , R. and Osbourne , N. N. 1982 . “ Localization of the Thy-1 antigen to the surfaces of rat retinal ganglion cells ” . In Neuroimmunology , Edited by: Brockes , J. 183 – 214 . New York : Plenum Press .
   Google Scholar
• Beretta , S. , Ferrarese , C. , Wood , J. P. , Osborne , N. N. and Carelli , V. 2006 . Pathogenesis of retinal ganglion cell death in Leber hereditary optic neuropathy (LHON): Possible involvement of mitochondria, light and glutamate . Mitochondrion , 6 : 102 – 103 .
   Google Scholar
• Bernstein , S. L. , Guo , Y. , Slater , B. J. , Puche , A. and Kelman , S. E. 2007 . Neuron stress and loss following rodent anterior ischemic optic neuropathy in double-reporter transgenic mice . Invest. Ophthalmol. Vis. Sci. , 48 : 2304 – 2310 .
   Google Scholar
• Besch , D. , Leo-Kottler , B. , Zrenner , E. and Wissinger , B. 1999 . Leber's hereditary optic neuropathy: clinical and molecular genetic findings in a patient with a new mutation in the ND6 gene . Graefes. Arch. Clin. Exp. Ophthalmol. , 237 : 745 – 752 .
   PubMed Web of Science ®Google Scholar
• Betarbet , R. , Sherer , T. B. , MacKenzie , G. , Garcia-Osuna , M. , Panov , A. V. and Greenamyre , J. T. 2000 . Chronic systemic pesticide exposure reproduces features of Parkinson's disease . Nat. Neurosci. , 3 : 1301 – 1306 .
   PubMed Web of Science ®Google Scholar
• Bishop , D. L. , Misgeld , T. , Walsh , M. K. , Gan , W. B. and Lichtman , J. W. 2004 . Axon branch removal at developing synapses by axosome shedding . Neuron , 44 : 651 – 661 .
   Google Scholar
• Biss , D. P. , Sumorok , D. , Burns , S. A. , Webb , R. H. , Zhou , Y. , Bifano , T. G. , Cote , D. , Veilleux , I. , Zamiri , P. and Lin , C. P. 2007 . In vivo fluorescent imaging of the mouse retina using adaptive optics . Opt. Lett. , 32 : 659 – 661 .
   Google Scholar
• Brown , M. D. , Voljavec , A. S. , Lott , M. T. , MacDonald , I. and Wallace , D. C. 1992 . Leber's hereditary optic neuropathy: A model for mitochondrial neurodegenerative diseases . FASEB J. , 6 : 2791 – 2799 .
   PubMed Web of Science ®Google Scholar
• Carelli , V. , Ross-Cisneros , F. N. and Sadun , A. A. 2002 . Optic nerve degeneration and mitochondrial dysfunction: genetic and acquired optic neuropathies . Neurochem. Int. , 40 : 573 – 584 .
   PubMed Web of Science ®Google Scholar
• Coombs , J. , van der List , D. , Wang , G. Y. and Chalupa , L. M. 2006 . Morphological properties of mouse retinal ganglion cells . Neuroscience , 140 : 123 – 136 .
   Google Scholar
• Degli Esposti , M. 1998 . Inhibitors of NADH-ubiquinone reductase: An overview . Biochim. Biophys. Acta , 1364 : 222 – 235 .
   PubMed Web of Science ®Google Scholar
• Ernster , L. , Jalling , O. , Low , H. and Lindberg , O. 1955 . Alternative pathways of mitochondrial DPNH oxidation, studied with amytal . Exp. Cell. Res. , 3 : 124 – 132 .
   Google Scholar
• Feng , G. , Mellor , R. H. , Bernstein , M. , Keller-Peck , C. , Nguyen , Q. T. , Wallace , M. , Nerbonne , J. M. , Lichtman , J. W. and Sanes , J. R. 2000 . Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP . Neuron , 28 : 41 – 51 .
   PubMed Web of Science ®Google Scholar
• Ferrante , R. J. , Schulz , J. B. , Kowall , N. W. and Beal , M. F. 1997 . Systemic administration of rotenone produces selective damage in the striatum and globus pallidus, but not in the substantia nigra . Brain Res. , 753 : 157 – 162 .
   PubMed Web of Science ®Google Scholar
• Galluzzi , L. , Maiuri , M. C. , Vitale , I. , Zischka , H. , Castedo , M. , Zitvogel , L. and Kroemer , G. 2007 . Cell death modalities: Classification and pathophysiological implications . Cell Death Differ. , 14 : 1237 – 1243 .
   PubMed Web of Science ®Google Scholar
• Gastinger , M. J. , Kunselman , A. R. , Conboy , E. E. , Bronson , S. K. and Barber , A. J. 2008 . Dendrite remodeling and other abnormalities in the retinal ganglion cells of Ins2 Akita diabetic mice . Invest. Ophthalmol. Vis. Sci. , 49 : 2635 – 2642 .
   PubMed Web of Science ®Google Scholar
• Greenamyre , J. T. , Sherer , T. B. , Betarbet , R. and Panov , A. V. 2001 . Complex I and Parkinson's disease . IUBMB Life , 52 : 135 – 141 .
   PubMed Web of Science ®Google Scholar
• Hauptmann , S. , Scherping , I. , Drose , S. , Brandt , U. , Schulz , K. L. , Jendrach , M. , Leuner , K. , Eckert , A. and Muller , W. E. 2008 . Mitochondrial dysfunction: An early event in Alzheimer pathology accumulates with age in AD transgenic mice . Neurobiol. Aging , in press
   Google Scholar
• Haverkamp , S. and Wassle , H. 2000 . Immunocytochemical analysis of the mouse retina . J. Comp. Neurol. , 424 : 1 – 23 .
   PubMed Web of Science ®Google Scholar
• Hayworth , C. R. , Moody , S. E. , Chodosh , L. A. , Krieg , P. , Rimer , M. and Thompson , W. J. 2006 . Induction of neuregulin signaling in mouse schwann cells in vivo mimics responses to denervation . J. Neurosci. , 26 : 6873 – 6884 .
   Google Scholar
• Isenberg , J. S. and Klaunig , J. E. 2000 . Role of the mitochondrial membrane permeability transition (MPT) in rotenone-induced apoptosis in liver cells . Toxicol. Sci. , 53 : 340 – 351 .
   PubMed Web of Science ®Google Scholar
• Kang , H. , Tian , L. and Thompson , W. 2003 . Terminal Schwann cells guide the reinnervation of muscle after nerve injury . J. Neurocytol. , 32 : 975 – 985 .
   Google Scholar
• Leung , C. K. , Lindsey , J. D. , Crowston , J. G. , Ju , W. K. , Liu , Q. , Bartsch , D. U. and Weinreb , R. N. 2008 . In vivo imaging of murine retinal ganglion cells . J. Neurosci. Methods , 168 : 475 – 478 .
   Google Scholar
• Lin , B. and Masland , R. H. 2005 . Synaptic contacts between an identified type of ON cone bipolar cell and ganglion cells in the mouse retina . Eur. J. Neurosci. , 21 : 1257 – 1270 .
   Google Scholar
• Lindahl , P. E. and Oberg , K. E. 1961 . The effect of rotenone on respiration and its point of attack . Exp. Cell. Res. , 23 : 228 – 237 .
   PubMed Web of Science ®Google Scholar
• Luft , R. 1994 . The development of mitochondrial medicine . Proc. Natl. Acad. Sci. USA , 91 : 8731 – 8738 .
   PubMed Web of Science ®Google Scholar
• Maass , A. , von Leithner , P. L. , Luong , V. , Guo , L. , Salt , T. E. , Fitzke , F. W. and Cordeiro , M. F. 2007 . Assessment of rat and mouse RGC apoptosis imaging in vivo with different scanning laser ophthalmoscopes . Curr. Eye Res. , 32 : 851 – 861 .
   PubMed Web of Science ®Google Scholar
• Mackey , D. A. , Oostra , R. J. , Rosenberg , T. , Nikoskelainen , E. , Bronte-Stewart , J. , Poulton , J. , Harding , A. E. , Govan , G. , Bolhuis , P. A. and Norby , S. 1996 . Primary pathogenic mtDNA mutations in multigeneration pedigrees with Leber hereditary optic neuropathy . Am. J. Hum. Genet. , 59 : 481 – 485 .
   PubMed Web of Science ®Google Scholar
• Man , P. Y. , Turnbull , D. M. and Chinnery , P. F. 2002 . Leber hereditary optic neuropathy . J. Med. Genet. , 39 : 162 – 169 .
   PubMed Web of Science ®Google Scholar
• Marella , M. , Seo , B. B. , Matsuno-Yagi , A. and Yagi , T. 2007 . Mechanism of cell death caused by complex I defects in a rat dopaminergic cell line . J. Biol. Chem. , 282 : 24146 – 24156 .
   PubMed Web of Science ®Google Scholar
• Panov , A. , Dikalov , S. , Shalbuyeva , N. , Taylor , G. , Sherer , T. and Greenamyre , J. T. 2005 . Rotenone model of Parkinson disease: Multiple brain mitochondria dysfunctions after short term systemic rotenone intoxication . J. Biol. Chem. , 280 : 42026 – 42035 .
   PubMed Web of Science ®Google Scholar
• Patel , A. J. , Lauritzen , I. , Lazdunski , M. and Honore , E. 1998 . Disruption of mitochondrial respiration inhibits volume-regulated anion channels and provokes neuronal cell swelling . J. Neurosci. , 18 : 3117 – 3123 .
   Google Scholar
• Rojas , J. C. , Saavedra , J. A. and Gonzalez-Lima , F. 2008 . Neuroprotective effects of memantine in a mouse model of retinal degeneration induced by rotenone . Brain Res. , 1215 : 208 – 217 .
   Google Scholar
• Schaefer , A. M. , Sanes , J. R. and Lichtman , J. W. 2005 . A compensatory subpopulation of motor neurons in a mouse model of amyotrophic lateral sclerosis . J. Comp. Neurol. , 490 : 209 – 219 .
   PubMed Web of Science ®Google Scholar
• Schapira , A. H. 1998 . Human complex I defects in neurodegenerative diseases . Biochim. Biophys. Acta , 1364 : 261 – 270 .
   PubMed Web of Science ®Google Scholar
• Sherer , T. B. , Betarbet , R. , Stout , A. K. , Lund , S. , Baptista , M. , Panov , A. V. , Cookson , M. R. and Greenamyre , J. T. 2002 . An in vitro model of Parkinson's disease: linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage . J. Neurosci. , 22 : 7006 – 7015 .
   PubMed Web of Science ®Google Scholar
• Sherer , T. B. , Betarbet , R. , Testa , C. M. , Seo , B. B. , Richardson , J. R. , Kim , J. H. , Miller , G. W. , Yagi , T. , Matsuno-Yagi , A. and Greenamyre , J. T. 2003 . Mechanism of toxicity in rotenone models of Parkinson's disease . J. Neurosci. , 23 : 10756 – 10764 .
   PubMed Web of Science ®Google Scholar
• Singer , T. P. and Ramsay , R. R. 1994 . The reaction sites of rotenone and ubiquinone with mitochondrial NADH dehydrogenase . Biochim. Biophys. Acta , 1187 : 198 – 202 .
   PubMed Web of Science ®Google Scholar
• Sun , D. , Vingrys , A. J. and Kalloniatis , M. 2007 . Metabolic and functional profiling of the normal rat retina . J. Comp. Neurol. , 505 : 92 – 113 .
   Web of Science ®Google Scholar
• Trachtenberg , J. T. , Chen , B. E. , Knott , G. W. , Feng , G. , Sanes , J. R. , Welker , E. and Svoboda , K. 2002 . Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex . Nature , 420 : 788 – 794 .
   PubMed Web of Science ®Google Scholar
• Valla , J. , Berndt , J. D. and Gonzalez-Lima , F. 2001 . Energy hypometabolism in posterior cingulate cortex of Alzheimer's patients: Superficial laminar cytochrome oxidase associated with disease duration . J. Neurosci. , 21 : 4923 – 4930 .
   PubMed Web of Science ®Google Scholar
• Walsh , M. K. and Lichtman , J. W. 2003 . In vivo time-lapse imaging of synaptic takeover associated with naturally occurring synapse elimination . Neuron , 37 : 67 – 73 .
   PubMed Web of Science ®Google Scholar
• Wang , L. , Dong , J. , Cull , G. , Fortune , B. and Cioffi , G. A. 2003 . Varicosities of intraretinal ganglion cell axons in human and nonhuman primates . Invest. Ophthalmol. Vis. Sci. , 44 : 2 – 9 .
   PubMed Web of Science ®Google Scholar
• Zhang , X. , Jones , D. and Gonzalez-Lima , F. 2002 . Mouse model of optic neuropathy caused by mitochondrial complex I dysfunction . Neurosci. Lett. , 326 : 97 – 100 .
   PubMed Web of Science ®Google Scholar
• Zhang , X. , Jones , D. and Gonzalez-Lima , F. 2006a . Neurodegeneration produced by rotenone in the mouse retina: A potential model to investigate environmental pesticide contributions to neurodegenerative diseases . J. Toxicol. Environ. Health A , 69 : 1681 – 1697 .
   PubMed Web of Science ®Google Scholar
• Zhang , X. , Rojas , J. C. and Gonzalez-Lima , F. 2006b . Methylene blue prevents neurodegeneration caused by rotenone in the retina . Neurotoxicol. Res. , 9 : 47 – 57 .
   PubMed Web of Science ®Google Scholar