Analysis and Integration of Developmental Neurotoxicity and Ancillary Data into Risk Assessment: A Case Study of Dimethoate

REFERENCES

• Brooker , A. J. and Stubbs , A. 1990 . Dimethoate: Dietary range finding study in mature male and female rats and their juvenile offspring , Huntingdon, Cambridgeshire, England : Huntingdon Research Center Ltd .
   Google Scholar
• Brooker , A. J. , Homan , B. A. , Parker , C. A. , Offer , J. M. , Anderson , A. and Dawe , I. S. 1992 . The effect of dimethoate on reproductive function of two generations in the rat , Huntingdon, Cambridgeshire, England : Huntingdon Research Center Ltd .
   Google Scholar
• Bu , J. , Yan , L. , Chen , Y. , Chu , J. X. , Xie , X. F. and Chen , T. P. 2001 . Prospective study of lethal blood concentrations of organophosphorous in humans . Fa Yi Xue Za Zhi , 17 : 21 – 24 .
   Google Scholar
• Carey , L. C. , Berbee , P. L. , Coyle , P. , Philcox , J. C. and Rofe , A. M. 2003 . Zinc treatment prevents lipopolysaccharide-induced teratogenicity in mice . Birth Defects Res. A Clin. Mol. Teratol. , 67 : 240 – 245 .
   Google Scholar
• Carey , L. C. , Coyle , P. , Philcox , J. C. and Rofe , A. M. 2000 . Maternal ethanol exposure is associated with decreased plasma zinc and increased fetal abnormalities in normal but not metallothionein-null mice . Alcohol Clin. Exp. Res. , 24 : 213 – 219 .
   Google Scholar
• Daston , G. P. 1994 . “ Relationships between maternal and developmental toxicity ” . In Developmental toxicology , 2nd , Edited by: Kimmel , C. A. and Buelke-Sam , J. 189 – 201 . New York : Raven Press .
   Google Scholar
• Daston , G. , Faustman , E. , Ginsburg , G. , Fenner-Crisp , P. , Olin , S. , Sonawane , B. , Bruckner , J. and Breslin , W. 2004 . A framework for assessing risks to children from exposure to environmental agents . Environ. Health Perspect. , 112 : 238 – 256 .
   PubMed Web of Science ®Google Scholar
• Davanzo , F. , Settimi , L. , Fraaoni , L. , Maiozzi , P. , Travaglia , A. and Marcello , I. 2004 . Agricultural pesticide-related poisonings in Italy: Cases reported to the Poison Control Centre of Milan in 2000–2001 . Epidemiol. Prev. , 28 : 330 – 337 .
   PubMedGoogle Scholar
• DeSesso , J. M. 1987 . Maternal factors and developmental toxicity . Teratogen. Carcinogen. Mutagen. , 7 : 225 – 240 .
   PubMedGoogle Scholar
• DeSesso , J. M. and Goeringer , G. C. 1990 . Developmental toxicity of hydroxylamine: An example of a maternally mediated effect . Toxicol. Ind. Health , 6 : 109 – 121 .
   Google Scholar
• Duffy , J. Y. , Baines , D. , Overmann , G. J. , Keen , C. L. and Daston , G. P. 1997 . Repeated administration of alpha-hederin results in alterations in maternal zinc status and adverse developmental outcome in the rat . Teratology , 56 : 327 – 334 .
   PubMedGoogle Scholar
• Eddleston , M. , Eyer , P. , Worek , F. , Mohammed , F. , Senarathna , L. , von Meyer , L. , Juszczak , E. , Hittarage , A. , Azher , S. , Dissanayake , W. , Sheriff , M. H. R. , Szinicz , L. , Dawson , A. H. and Buckley , N. A. 2005 . Differences between organophosphorous insecticides in human self-poisoning . Lancet , 366 : 1452 – 1459 .
   PubMed Web of Science ®Google Scholar
• Haseman , J. K. and Hogan , M. D. 1975 . Selection of the experimental unit in teratology studies . Teratology , 12 : 165 – 171 .
   PubMedGoogle Scholar
• Holson , J. F. , DeSesso , J. M. , Jacobson , C. F. and Farr , C. H. 2000 . Appropriate use of animal models in the assessment of risk during prenatal development: An illustration using inorganic arsenic . Teratology , 62 : 51 – 71 .
   Google Scholar
• International Life Sciences Institute. 1999. An evaluation and interpretation of reproductive endpoints for human health risk assessment, Report prepared by an expert panel. Washington, DC: ILSI.
   Google Scholar
• Keen , C. L. , Clegg , M. S. , Hanna , L. A. , Lanoue , L. , Rogers , J. M. , Daston , G. P. , Oteiza , P. and Uriu-Adams , J. Y. 2003a . The plausibility of micronutrient deficiencies being a significant contributing factor to the occurrence of pregnancy complications . J. Nutr. , 133 : 1597S – 1605S .
   PubMed Web of Science ®Google Scholar
• Keen , C. L. , Hanna , L. A. , Lanoue , L. , Uriu-Adams , J. Y. , Rucker , R. B. and Clegg , M. S. 2003b . Developmental consequences of trace mineral deficiencies in rodents: Acute and long-term effects . J. Nutr. , 133 : 1477S – 1480S .
   PubMed Web of Science ®Google Scholar
• Khera , K. S. 1987 . Maternal toxicity in humans and animals: Effects on fetal development and criteria for detection . Teratogen. Carcinogen. Mutagen. , 7 : 287 – 295 .
   PubMedGoogle Scholar
• Khera , K. S . 1991 . Chemically induced alterations in maternal homeostasis and histology of conceptus: Their etiologic significance in rat and fetal anomalies . Teratology , 44 : 259 – 297 .
   PubMedGoogle Scholar
• Mellert , W. , Hellwig , J. , Gembardt , C. , Deckert , K. and van Ravenzwaay , B. 2003 . Dimethoate—Two-generation reproduction toxicity study in Wistar rats: Administration in the diet , Ludwigshafen/Rhein, Germany : Experimental Toxicology and Ecology, BASF Aktiengesellschaft .
   Google Scholar
• Morford , L. L. , Henck , J. W. , Breslin , W. J. and DeSesso , J. M. 2004 . Hazard identification and predictability of children's health risk from animal data . Environ. Health Perspect. , 112 : 266 – 271 .
   PubMedGoogle Scholar
• Myers , D. P. 2001 . Dimethoate effects on cholinesterase in the CD rat (adult and juvenile) by oral gavage administration , Cambridgeshire, UK : Huntingdon Life Sciences .
   Google Scholar
• Myers , D. P. 2003 . Dimethoate developmental neurotoxicity study in the CD rat by oral gavage administration (Final report with consolidation of amendments 1 and 2) , Cambridgeshire, UK : Huntingdon Life Sciences .
   Google Scholar
• Reiss , R. and Gaylor , D. 2005 . Use of benchmark dose and meta-analysis to determine the most sensitive endpoint for risk assessment for dimethoate . Regul. Toxicol. Pharmacol. , 43 : 55 – 65 .
   PubMed Web of Science ®Google Scholar
• Sheets , L. 2000 . A consideration of age-dependent differences in susceptibility to organophosphorous and pyrethroid insecticides . Neurotoxicology , 21 : 57 – 63 .
   PubMed Web of Science ®Google Scholar
• Tang , J. , Carr , R. L. and Chambers , J. E. 2003 . The effects of repeated oral exposures to methyl parathion on rat brain cholinesterase and muscarinic receptors during postnatal development . Toxicol. Sci. , 76 : 400 – 406 .
   PubMed Web of Science ®Google Scholar
• Tsatsakis , A. M. , Aguridakis , P. , Michalodimitrakis , M. N. , Tsaklov , A. K. , Alegakis , A. K. , Koumantakis , E. and Troulakis , G. 1996 . Experiences with acute organophosphate poisonings in Crete . Vet. Hum. Toxicol. , 38 : 101 – 107 .
   PubMedGoogle Scholar
• Taubeneck , M. W. , Daston , G. P. , Rogers , J. M. and Keen , C. L. 1994 . Altered maternal zinc metabolism following exposure to diverse developmental toxicants . Reprod. Toxicol. , 8 : 25 – 40 .
   PubMed Web of Science ®Google Scholar
• Tyl , R. W. , Crofton , K. , Moretto , A. , Moser , V. , Sheets , L. P. and Sobotka , T. J. 2008 . Identification and interpretation of developmental neurotoxicity effects: A report from the ILSI Research Foundation/Risk Science Institute expert working group on neurodevelopmental endpoints . Neurotoxicol. Teratol. , 30 : 349 – 381 .
   PubMed Web of Science ®Google Scholar
• Weaver , I. C. , Cervoni , N. , Champagne , F. A. , Alessio , A. C. , Sharma , S. , Seckl , J. R. , Dymov , S. , Szyf , M. and Meaney , M. J. 2004 . Epigenetic programming by maternal behavior . Nat. Neurosci. , 7 : 791 – 792 .
   PubMedGoogle Scholar
• Wilcoxon , F. 1945 . Individual comparisons by ranking methods . Biometrics Bull. , 1 : 80 – 83 .
   Web of Science ®Google Scholar