Nanoparticle Inhalation Impairs Endothelium-Dependent Vasodilation in Subepicardial Arterioles

REFERENCES

• American College of Sports Medicine, , 2005. American College of Sports Medicine guidelines for exercise testing and prescription. Indianapolis, IN: American College of Sports Medicine; 2005.
   Google Scholar
• Araujo, J. A., Barajas, B., Kleinman, M., Wang, X., Bennett, B. J., Gong, K. W., Navab, M., Harkema, J., Sioutas, C., Lusis, A. J., and Nel, A. E., 2008. Ambient particulate pollutants in the ultrafine range promote early atherosclerosis and systemic oxidative stress, Circ. Res. 102 (2008), pp. 589–596.
   PubMed Web of Science ®Google Scholar
• Bottcher, M., Madsen, M. M., Refsgaard, J., Buus, N. H., Dorup, I., Nielsen, T. T., and Sorensen, K., 2001. Peripheral flow response to transient arterial forearm occlusion does not reflect myocardial perfusion reserve, Circulation 103 (2001), pp. 1109–1114.
   PubMed Web of Science ®Google Scholar
• Briet, M., Collin, C., Laurent, S., Tan, A., Azizi, M., Agharazii, M., Jeunemaitre, X., Alhenc-Gelas, F., and Boutouyrie, P., 2007. Endothelial function and chronic exposure to air pollution in normal male subjects, Hypertension 50 (2007), pp. 970–976.
   PubMed Web of Science ®Google Scholar
• Brook, R. D., Franklin, B., Cascio, W., Hong, Y., Howard, G., Lipsett, M., Luepker, R., Mittleman, M., Samet, J., Smith, S. C., and Tager, I., 2004. Air pollution and cardiovascular disease: A statement for healthcare professionals from the Expert Panel on Population and Prevention Science of the American Heart Association, Circulation 10 (2004), pp. 2655–2671.
   Google Scholar
• Brunauer, S., Emmett, P. H., and Teller, E., 1938. Adsorption of gases in multimolecular layers, J. Am. Chem. Soc 60 (1938), pp. 309–319.
   Web of Science ®Google Scholar
• Campen, M. J., Babu, N. S., Helms, G. A., Pett, S., Wernly, J., Mehran, R., and McDonald, J. D., 2005. Nonparticulate components of diesel exhaust promote constriction in coronary arteries from ApoE-/- mice, Toxicol. Sci. 88 (2005), pp. 95–102.
   PubMed Web of Science ®Google Scholar
• Chen, H. W., Su, S. F., Chien, C. T., Lin, W. H., Yu, S. L., Chou, C. C., Chen, J. J., and Yang, P. C., 2006. Titanium dioxide nanoparticles induce emphysema-like lung injury in mice, FASEB J. 20 (2006), pp. 2393–2395.
   PubMed Web of Science ®Google Scholar
• Chilian, W. M., Eastham, C. L., and Marcus, M. L., 1986. Microvascular distribution of coronary vascular resistance in beating left ventricle, Am. J. Physiol. 251 (1986), pp. H779–H788.
   PubMed Web of Science ®Google Scholar
• de Haar, C., Hassing, I., Bol, M., Bleumink, R., and Pieters, R., 2006. Ultrafine but not fine particulate matter causes airway inflammation and allergic airway sensitization to co-administered antigen in mice, Clin. Exp. Allergy 36 (2006), pp. 1469–1479.
   PubMed Web of Science ®Google Scholar
• Dockery, D. W., 2001. Epidemiologic evidence of cardiovascular effects of particulate air pollution, Environ. Health Perspect. 109 (suppl. 4) (2001), pp. 483–486.
   PubMed Web of Science ®Google Scholar
• Dominici, F., McDermott, A., Daniels, M., Zeger, S. L., and Samet, J. M., 2005. Revised analysis of the national morbidity, mortality and air pollution study: Mortality among residents in 90 cities, J. Toxicol. Environ. Health A 68 (2005), pp. 1071–1092.
   PubMed Web of Science ®Google Scholar
• Dreher, K. L., 2004. Health and environmental impact of nanotechnology: Toxicological assessment of manufactured nanoparticles, Toxicol. Sci. 77 (2004), pp. 3–5.
   PubMed Web of Science ®Google Scholar
• Godleski, J. J., Verrier, R. L., Koutrakis, P., Catalano, P., Coull, B., Reinisch, U., Lovett, E. G., Lawrence, J., Murthy, G. G., Wolfson, J. M., Clarke, R. W., Nearing, B. D., and Killingsworth, C., 2000. Mechanisms of morbidity and mortality from exposure to ambient air particles, Res. Rep. Health Effects Inst. (2000), pp. 5–88, discussion 89–103.
   PubMedGoogle Scholar
• Goldberg, M. S., Bailar, J. C., Burnett, R. T., Brook, J. R., Tamblyn, R., Bonvalot, Y., Ernst, P., Flegel, K. M., Singh, R. K., and Valois, M. F., 2000. Identifying subgroups of the general population that may be susceptible to short-term increases in particulate air pollution: A time-series study in Montreal, Quebec, Res. Rep. Health Effects Inst. (2000), pp. 7–113, discussion 115–120.
   PubMedGoogle Scholar
• Goldberg, M. S., Burnett, R. T., Bailar, J. C., Tamblyn, R., Ernst, P., Flegel, K., Brook, J., Bonvalot, Y., Singh, R., Valois, M. F., and Vincent, R., 2001. Identification of persons with cardiorespiratory conditions who are at risk of dying from the acute effects of ambient air particles, Environ. Health Perspect. 109 (suppl. 4) (2001), pp. 487–494.
   PubMed Web of Science ®Google Scholar
• Grassian, V. H., O'Shaughnessy, P. T, Adamcakova-Dodd, A., Pettibone, J. M., and Thorne, P. S., 2007. Inhalation exposure study of titanium dioxide nanoparticles with a primary particle size of 2 to 5 nm, Environ. Health Perspect. 115 (2007), pp. 397–402.
   PubMed Web of Science ®Google Scholar
• Hansen, C. S., Sheykhzade, M., Moller, P., Folkmann, J. K., Amtorp, O., Jonassen, T., and Loft, S., 2007. Diesel exhaust particles induce endothelial dysfunction in apoE-/- mice, Toxicol. Appl. Pharmacol. 219 (2007), pp. 24–32.
   PubMed Web of Science ®Google Scholar
• He, P., Zhang, H., Zhu, L., Jiang, Y., and Zhou, X., 2006. Leukocyte-platelet aggregate adhesion and vascular permeability in intact microvessels: Role of activated endothelial cells, Am. J. Physiol. Heart Circ. Physiol. 291 (2006), pp. H591–H599.
   PubMed Web of Science ®Google Scholar
• Huang, A., Sun, D., Koller, A., and Kaley, G., 2000. 17Beta-estradiol restores endothelial nitric oxide release to shear stress in arterioles of male hypertensive rats, Circulation 101 (2000), pp. 94–100.
   PubMed Web of Science ®Google Scholar
• Hurum, D. C., Gray, K. A., Rajh, T., and Thurnauer, M. C., 2005. Recombination pathways in the Degussa P25 formulation of TiO2: Surface versus lattice mechanisms, J. Phys. Chem. B 109 (2005), pp. 977–980.
   PubMed Web of Science ®Google Scholar
• Knuckles, T. L., Lund, A. K., Lucas, S. N., and Campen, M. J., 2008. Diesel exhaust exposure enhances venoconstriction via uncoupling of eNOS, Toxicol. Appl. Pharmacol. 230 (2008), pp. 346–351.
   PubMed Web of Science ®Google Scholar
• Kodavanti, U. P., Schlaweiler, M. C., Ledbetter, A. D., Hauser, R., Christiani, D. C., McGee, J., Richards, J. R., and Costa, D. L., 2002. Temporal association between pulmonary and systemic effects of particulate matter in healthy and cardiovascular compromised rats, J. Toxicol. Environ. Health A 65 (2002), pp. 1545–1569.
   PubMed Web of Science ®Google Scholar
• http://www.hvbg.de/e/bia/pub/rep/rep04/pdf_datei/biar0703/topic_a.pdf, Kreyling, W. 2003. Deposition, retention, and clearance of ultrafine particles. BIA-Workshop, Ultrafine Aerosols at Workplaces.
   Google Scholar
• Kuo, L., Davis, M., and Chilian, W. M., 1990. Endothelium-dependent, flow-induced dilation of isolated coronary arterioles, Am. J. Physiol. 259 (1990), pp. H1063–H1070.
   PubMed Web of Science ®Google Scholar
• Kuo, L., Davis, M. J., and Chilian, W. M., 1988. Myogenic activity in isolated subepicardial and subendocardial coronary arterioles, Am. J. Physiol. 255 (1988), pp. H1558–H1562.
   PubMedGoogle Scholar
• Kuo, L., Davis, M. J., and Chilian, W. M., 1995. Longitudinal gradients for endothelium-dependent and -independent vascular responses in the coronary microcirculation, Circulation 92 (1995), pp. 518–525.
   PubMed Web of Science ®Google Scholar
• Murphy, R. A., 1980. "Mechanics of vascular smooth muscle". In: Handbook of physiology. The cardiovascular system. The vascular system, section 2. Vol. II. Bethesda, MD: American Physiological Society; 1980. pp. 325–352.
   Google Scholar
• http://www.cdc.gov/niosh/review/public/TIO2/pdfs/TIO2Draft.pdf, NIOSH. 2009. NIOSH current intelligence bulletin: Evaluation of health hazard and recommendation for occupational exposure to titanium dioxide.
   Google Scholar
• Nurkiewicz, T. R., and Boegehold, M. A., 1999. Limitation of arteriolar myogenic activity by local nitric oxide: Segment-specific effect of dietary salt, Am. J. Physiol. 277 (1999), pp. H1946–H1955.
   PubMedGoogle Scholar
• Nurkiewicz, T. R., Porter, D. W., Barger, M., Millecchia, L., Rao, K. M., Marvar, P. J., Hubbs, A. F., Castranova, V., and Boegehold, M. A., 2006. Systemic microvascular dysfunction and inflammation after pulmonary particulate matter exposure, Environ. Health Perspect. 11 (2006), pp. 412–419.
   Google Scholar
• Nurkiewicz, T. R., Porter, D. W., Hubbs, A. F., Cumpston, J. L., Chen, B. T., Frazer, D. G., and Castranova, V., 2008. Nanoparticle inhalation augments particle-dependent systemic microvascular dysfunction, Part. Fibre Toxicol. 5 (2008), p. 1.
   PubMed Web of Science ®Google Scholar
• Nurkiewicz, T. R., Porter, D. W., Hubbs, A. F., Stone, S., Chen, B. T., Frazer, D. G., Boegehold, M. A., and Castranova, V., 2009. Pulmonary nanoparticle exposure disrupts systemic microvascular nitric oxide signaling, Toxicol. Sci. 110 (2009), pp. 191–203.
   PubMed Web of Science ®Google Scholar
• O'Neill, M. S, Veves, A., Zanobetti, A., Sarnat, J. A., Gold, D. R., Economides, P. A., Horton, E. S., and Schwartz, J., 2005. Diabetes enhances vulnerability to particulate air pollution-associated impairment in vascular reactivity and endothelial function, Circulation 111 (2005), pp. 2913–2920.
   PubMed Web of Science ®Google Scholar
• Oberdorster, G., Sharp, Z., Atudorei, V., Elder, A., Gelein, R., Kreyling, W., and Cox, C., 2004. Translocation of inhaled ultrafine particles to the brain, Inhal. Toxicol. 16 (2004), pp. 437–445.
   PubMed Web of Science ®Google Scholar
• Pope, C. A., Burnett, R. T., Thurston, G. D., Thun, M. J., Calle, E. E., Krewski, D., and Godleski, J. J., 2004. Cardiovascular mortality and long-term exposure to particulate air pollution: Epidemiological evidence of general pathophysiological pathways of disease, Circulation 109 (2004), pp. 71–77.
   PubMed Web of Science ®Google Scholar
• Pope, C. A., Muhlestein, J. B., May, H. T., Renlund, D. G., Anderson, J. L., and Horne, B. D., 2006. Ischemic heart disease events triggered by short-term exposure to fine particulate air pollution, Circulation 114 (2006), pp. 2443–2448.
   PubMed Web of Science ®Google Scholar
• Sager, T. M., Kommineni, C., and Castranova, V., 2008. Pulmonary response to intratracheal instillation of ultrafine versus fine titanium dioxide: Role of particle surface area, Part. Fibre Toxicol. 5 (2008), p. 17.
   PubMed Web of Science ®Google Scholar
• Samet, J. M., Dominici, F., Curriero, F. C., Coursac, I., and Zeger, S. L., 2000. Fine particulate air pollution and mortality in 20 U.S. cities, 1987–1994, N. Engl. J. Med. 343 (2000), pp. 1742–1749.
   PubMed Web of Science ®Google Scholar
• Schwartz, J., and Morris, R., 1995. Air pollution and hospital admissions for cardiovascular disease in Detroit, Michigan, Am. J. Epidemiol. 142 (1995), pp. 23–35.
   PubMed Web of Science ®Google Scholar
• Shieh, K. J., Li, M., Lee, Y. H., Sheu, S. D., Liu, Y. T., and Wang, Y. C., 2006. Antibacterial performance of photocatalyst thin film fabricated by defection effect in visible light, Nanomedicine 2 (2006), pp. 121–126.
   PubMed Web of Science ®Google Scholar
• Shipley, R. D., and Muller-Delp, J. M., 2005. Aging decreases vasoconstrictor responses of coronary resistance arterioles through endothelium-dependent mechanisms, Cardiovasc. Res. 66 (2005), pp. 374–383.
   PubMed Web of Science ®Google Scholar
• Stone, K. C., Mercer, R. R., Freeman, B. A., Chang, L. Y., and Crapo, J. D., 1992. Distribution of lung cell numbers and volumes between alveolar and nonalveolar tissue, Am. Rev. Respir. Dis. 146 (1992), pp. 454–456.
   PubMed Web of Science ®Google Scholar
• Sun, D., Meng, T. T., Loong, T. H., and Hwa, T. J., 2004. Removal of natural organic matter from water using a nano-structured photocatalyst coupled with filtration membrane, Water Sci. Technol. 49 (2004), pp. 103–110.
   PubMed Web of Science ®Google Scholar
• Tamagawa, E., Bai, N., Morimoto, K., Gray, C., Mui, T., Yatera, K., Zhang, X., Xing, L., Li, Y., Laher, I., Sin, D. D., Man, S. F., and van Eeden, S. F., 2008. Particulate matter exposure induces persistent lung inflammation and endothelial dysfunction, Am. J. Physiol. Lung Cell Mol. Physiol. 295 (2008), pp. L79–L85.
   PubMed Web of Science ®Google Scholar
• Tornqvist, H., Mills, N. L., Gonzalez, M., Miller, M. R., Robinson, S. D., Megson, I. L., Macnee, W., Donaldson, K., Soderberg, S., Newby, D. E., Sandstrom, T., and Blomberg, A., 2007. Persistent endothelial dysfunction in humans after diesel exhaust inhalation, Am. J. Respir. Crit. Care Med. 176 (2007), pp. 395–400.
   PubMed Web of Science ®Google Scholar
• Vasiliev, P. O., Faure, B., Ng, J. B., and Bergstrom, L., 2008. Colloidal aspects relating to direct incorporation of TiO2 nanoparticles into mesoporous spheres by an aerosol-assisted process, J. Colloid Interface Sci. 319 (2008), pp. 144–151.
   PubMed Web of Science ®Google Scholar
• Wallace, W. M., Goldstein, K., Taylor, A., and Teree, T. M., 1970. Thermal dehydration of the rat: Distribution of losses among tissues, Am. J. Physiol. 219 (1970), pp. 1544–1548.
   PubMedGoogle Scholar
• Wallenborn, J. G., McGee, J. K., Schladweiler, M. C., Ledbetter, A. D., and Kodavanti, U. P., 2007. Systemic translocation of particulate matter-associated metals following a single intratracheal instillation in rats, Toxicol. Sci. 98 (2007), pp. 231–239.
   PubMed Web of Science ®Google Scholar
• Watkinson, W. P., Campen, M. J., Nolan, J. P., and Costa, D. L., 2001. Cardiovascular and systemic responses to inhaled pollutants in rodents: Effects of ozone and particulate matter, Environ. Health Perspect. 109 (suppl. 4) (2001), pp. 539–546.
   PubMed Web of Science ®Google Scholar