131
Views
4
CrossRef citations to date
0
Altmetric
Original Articles

Bayesian Analysis of A Rat Formaldehyde DNA–Protein Cross-Link Model

, , , &
Pages 787-806 | Received 29 Oct 2009, Accepted 30 Jan 2010, Published online: 07 Apr 2010

REFERENCES

  • Barton , H. A. , Chiu , W. A. , Woodrow Setzer , R. , Andersen , M. E. , Bailer , A. J. , Bois , F. Y. , Dewoskin , R. S. , Hays , S. , Johanson , G. , Jones , N. , Loizou , G. , Macphail , R. C. , Portier , C. J. , Spendiff , M. and Tan , Y. M. 2007 . Characterizing uncertainty and variability in physiologically based pharmacokinetic models: State of the science and needs for research and implementation . Toxicol. Sci. , 99 : 395 – 402 .
  • Blair , A. , Stewart , P. A. , Hoover , R. N. , Fraumeni , J. F. Jr. , Walrath , J. , O'Berg , M. and Gaffey , W. 1987 . Cancers of the nasopharynx and oropharynx and formaldehyde exposure . JNCI , 78 : 191 – 193 .
  • Bois, F., Maszle, D., Revzan, K., Tillier, S., and Yuan, Z. 2005. MCSIM: logicielde simulation [MCSim simulation package]. Experimental Toxicology Unit, INERIS, Verneuil-en-Halatte, France http://toxi.ineris.fr/en/activites/toxicologie_quantitative/mcsim/mcsim.php
  • Bois , F. Y. 2000 . Statistical analysis of Clewell et al. PBPK model of trichloroethylene kinetics . Environ. Health Perspect. , 108 ( suppl. 2 ) : 307 – 316 .
  • Bortot , P. , Thomaseth , K. and Salvan , A. 2002 . Population toxicokinetic analysis of 2,3,7,8‐tetrachlorodibenzo-p-dioxin using Bayesian techniques . Stat. Med. , 21 : 533 – 547 .
  • Brooks , S. P. and Gelman , A. 1998 . General methods for monitoring convergence of iterative simulations . J. Comput. Graphical Stat. , 7 : 434 – 455 .
  • Casanova , M. , Deyo , D. F. and Heck , H. D. 1989 . Covalent binding of inhaled formaldehyde to DNA in the nasal mucos a of Fischer 344 rats: Analysis of formaldehyde and DNA by high-performance liquid chromatography and provisional pharmacokinetic interpretation . Fundam. Appl. Toxicol. , 12 : 397 – 417 .
  • Casanova , M. , Morgan , K. T. , Gross , E. A. , Moss , O. R. and Heck , H. A. 1994 . DNA-protein cross-links and cell replication at specific sites in the nose of F344 rats exposed subchronically to formaldehyde . Fundam. Appl. Toxicol. , 23 : 525 – 536 .
  • Casanova , M. , Morgan , K. T. , Steinhagen , W. H. , Everitt , J. I. , Popp , J. A. and Heck , H. D. 1991 . Covalent binding of inhaled formaldehyde to DNA in the respiratory tract of rhesus monkeys: Pharmacokinetics, rat-to-monkey interspecies scaling, and extrapolation to man . Fundam. Appl. Toxicol. , 17 : 409 – 428 .
  • Chiu , A. A. and Bois , F. Y. 2006 . Revisiting the population toxicokinetics of tetrachloroethylene . Arch. Toxicol. , 80 : 382 – 385 .
  • Chiu , W. A. and Bois , F. Y. 2007 . An approximate method for population toxicokinetic analysis with aggregated data . Agric. Biol. Environ. Stat. , 12 : 346 – 363 .
  • Conolly , R. B. , Kimbell , J. S. , Janszen , D. , Schlosser , P. M. , Kalisak , D. , Preston , J. and Miller , F. J. 2003 . Biologically motivated computational modeling of formaldehyde carcinogenicity in the F344 rat . Toxicol. Sci. , 75 : 432 – 447 .
  • Conolly , R. B. , Kimbell , J. S. , Janszen , D. , Schlosser , P. M. , Kalisak , D. , Preston , J. and Miller , F. J. 2004 . Human respiratory tract cancer risks of inhaled formaldehyde: Dose-response predictions derived from biologically-motivated computational modeling of a combined rodent and human dataset . Toxicol. Sci. , 82 : 279 – 296 .
  • Conolly , R. B. , Lilly , P. D. and Kimbell , J. S. 2000 . Simulation modeling of the tissue disposition of formaldehyde to predict nasal DNA–protein cross-links in Fischer 344 rats, rhesus monkeys, and humans . Environ. Health Perspect. , 108 ( suppl. 5 ) : 919 – 924 .
  • Harkema , J. R. 1991 . Comparative aspects of nasal airway anatomy: Relevance to inhalation toxicology . Toxicol. Pathol. , 19 : 321 – 336 .
  • Hubal , E. A. , Schlosser , P. M. , Conolly , R. B. and Kimbell , J. S. 1997 . Comparison of inhaled formaldehyde dosimetry predictions with DNA–protein cross-link measurements in the rat nasal passages . Toxicol. Appl. Pharmacol. , 143 : 47 – 55 .
  • Keller , D. A. and Heck , H. D. 1988 . Mechanistic studies on chloral toxicity: Relationship to trichloroethylene carcinogenesis . Toxicol. Lett. , 42 : 183 – 191 .
  • Kerns , W. D. , Pavkov , K. L. , Donofrio , D. J. , Gralla , E. J. and Swenberg , J. A. 1983 . Carcinogenicity of formaldehyde in rats and mice after long-term inhalation exposure . Cancer Res. , 43 : 4382 – 4392 .
  • Kimbell , J. S. , Gross , E. A. , Joyner , D. R. , Godo , M. N. and Morgan , K. T. 1993 . Application of computational fluid dynamics to regional dosimetry of inhaled chemicals in the upper respiratory tract of the rat . Toxicol. Appl. Pharmacol. , 121 : 253 – 263 .
  • Liu , Y. , Li , C. M. , Lu , Z. , Ding , S. , Yang , X. and Mo , J. 2006 . Studies on formation and repair of formaldehyde-damaged DNA by detection of DNA–protein crosslinks and DNA breaks . Front. Biosci. , 11 : 991 – 997 .
  • Monticello , T. M. , Miller , F. J. and Morgan , K. T. 1991 . Regional increases in rat nasal epithelial cell proliferation following acute and subchronic inhalation of formaldehyde . Toxicol. Appl. Pharmacol. , 111 : 409 – 421 .
  • Monticello , T. M. , Morgan , K. T. , Everitt , J. I. and Popp , J. A. 1989 . Effects of formaldehyde gas on the respiratory tract of rhesus monkeys. Pathology and cell proliferation . Am. J. Pathol. , 134 : 515 – 527 .
  • Monticello , T. M. , Swenberg , J. A. , Gross , E. A. , Leininger , J. R. , Kimbell , J. S. , Seilkop , S. , Starr , T. B. , Gibson , J. E. and Morgan , K. T. 1996 . Correlation of regional and nonlinear formaldehyde-induced nasal cancer with proliferating populations of cells . Cancer Res. , 56 : 1012 – 1022 .
  • Morris , J. B. , Hassett , D. N. and Blanchard , K. T. 1993 . A physiologically based pharmacokinetic model for nasal uptake and metabolism of nonreactive vapors . Toxicol. Appl. Pharmacol. , 123 : 120 – 129 .
  • Morris , J. B. 1997 . Dosimetry, toxicity and carcinogenicity of inspired acetaldehyde in the rat . Mutat. Res. , 380 : 113 – 124 .
  • Nong , A. , Tan , Y. M. , Krolski , M. E. , Wang , J. , Lunchick , C. , Conolly , R. B. and Clewell , H. J. 3rd . 2008 . Bayesian calibration of a physiologically based pharmacokinetic/pharmacodynamic model of carbaryl cholinesterase inhibition . J. Toxicol. Environ. Health A , 71 : 1363 – 1381 .
  • Quievryn , G. and Zhitkovich , A. 2000 . Loss of DNA-protein crosslinks from formaldehyde-exposed cells occurs through spontaneous hydrolysis and an active repair process linked to proteosome function . Carcinogenesis , 21 : 1573 – 1580 .
  • Smith, B. J. 2007. Bayesian Output Analysis Program (BOA) Version 1.1 user's manual. http://www.public-health.uiowa.edu/boa
  • Subramaniam , R. P. , Crump , K. S. , Van Landingham , C. , White , P. , Chen , C. and Schlosser , P. M. 2007 . Uncertainties in the CIIT model for formaldehyde-induced carcinogenicity in the rat: a limited sensitivity analysis—I . Risk Anal. , 27 : 1237 – 1254 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.