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Original Articles

Age-Specific Absolute and Relative Organ Weight Distributions For B6C3F1 Mice

Pages 76-99 | Received 31 May 2011, Accepted 15 Aug 2011, Published online: 30 Nov 2011

REFERENCES

  • Andersen , M. E. 1981 . A physiologically-based toxicokinetic description of metabolism of inhaled gases and vapors: analysis at steady state . Toxicol. Appl. Pharmacol. , 60 : 509 – 26 .
  • Bischoff , K. B. 1987 . “ Physiologically-based pharmacokinetic modeling ” . In Pharmacokinetics in risk assessment. Drinking water and health , Vol. 8 , 36 – 61 . Washington , DC : National Academy Press .
  • Brown , R. P. , Delp , M. D. , Lindstedt , S. L. , Rhomberg , L. R. and Beliles , R. P. 1997 . Physiological parameter values for physiologically based pharmacokinetic models . Toxicol. Ind. Health , 13 : 407 – 84 .
  • Clewell , H. J. and Andersen , M. E. 1985 . Risk assessment extrapolations and physiological modeling . Toxicol. Ind. Health , 14 : 111 – 31 .
  • Clewell , H. J. and Andersen , M. E. 1989 . Biologically motivated models for chemical risk assessment . Health Phys. , 57 ( suppl. 1 ) : 129 – 37 .
  • Clewell , H. J. , Teeguarden , J. , McDonald , T. , Sarangapani , R. , Lawrence , G. , Covington , T. , Gentry , R. and Shipp , A. 2002 . Review and evaluation of the potential impact of age- and gender-specific pharmacokinetic differences on tissue dosimetry . Crit. Rev. Toxicol. , 32 : 329 – 89 .
  • Cameron , T. P. , Hickman , R. L. , Kornreich , M. R. and Tarone , R. E. 1985 . History, survival, and growth patterns of B6C3F1 mice and F344 rats in the National Cancer Institute Carcinogenesis Testing Program . Fundam. Appl. Toxicol. , 5 : 526 – 38 .
  • David , R. M. , Clewell , H. J. , Gentry , P. R. , Covington , T. , Morgott , D. A. and Marino , D. J. 2006 . Revised assessment of cancer risk to dichloromethane using improved human metabolic parameters and Bayesian statistics . Regul. Pharmacol. Toxicol. , 45 : 55 – 65 .
  • Gentry , P. R. , Haber , L. T. , McDonald , T. B. , Zhao , Q. , Covington , T. , Nance , P. , Clewell , H. J. , Lipscomb , J. C. and Barton , H. A. 2004 . Data for physiologically based pharmacokinetic modeling in neonatal animals: Physiological parameters in mice and Sprague-Dawley rats . J. Child. Health , 2 : 363 – 411 .
  • Gur , E. and Waner , T. 1993 . The variability of organ weight background data in rats . Lab. Anim. , 27 : 65 – 72 .
  • Haseman , J. K. , Bourbina , J. and Eustis , S. L. 1994 . Effect of individual housing and other experimental design factors on tumor incidence in B6C3F1 mice . Fundam. Appl. Toxicol. , 23 : 44 – 52 .
  • Haseman , J. K. , Hailey , J. R. and Morris , R. W. 1998 . Spontaneous neoplasm incidences in Fischer 344 rats and B6C3F1 mice in two-year carcinogenicity studies: A National Toxicology Program update . Toxicol. Pathol. , 26 : 428 – 41 .
  • Hattis , D. , Ginsberg , G. , Sonawane , B. , Smolenski , S. , Russ , A. , Kozlak , M. and Goble , R. 2003 . Differences in pharmacokinetics between children and adults—II. Children's variability in drug elimination half-lives and in some parameters needed for physiologically-based pharmacokinetic modeling . Risk Anal. , 23 : 117 – 42 .
  • Iwata , H. , Hagiwara , T. , Katoh , M. , Yamamoto , S. , Yamakawa , S. , Shiga , A. , Hirouchi , Y. , Kobayashi , K. , Inoue , H. and Enomoto , M. 1993 . Historical control data of organ weight and gross findings in F344/DuCrj rats and B6C3F1 mice . Jikken Dobutsu , 42 : 383 – 96 .
  • Long , G. G. , Symanowski , J. T. and Roback , K. 1998 . Precision in data acquisition and reporting of organ weights in rats and mice . Toxicol. Pathol. , 26 : 316 – 18 .
  • Marino , D. J. , Clewell , H. J. I II , Gentry , P. R. , Covington , T. R. , David , R. M. and Morgott , D. A. 2006 . Bayesian PBPK and dose-response modeling of dichloromethane in mice . Regul. Pharmacol. Toxicol. , 45 : 44 – 54 .
  • Mirfazaelian , A. and Fisher , J. W. 2007 . Organ growth functions in maturing male Sprague-Dawley rats based on a collective database . J. Toxicol. Environ. Health A , 70 : 1052 – 1063 .
  • Mittwoch , U. 1979 . Lateral asymmetry of kidney weights in different populations of wild mice . Biol. J. Linn. Soc. , 11 : 295 – 300 .
  • Rao , G. N. and Crockett , P. W. 2003 . Effect of diet and housing on growth, body weight, survival and tumor incidences of B6C3F1 mice in chronic studies . Toxicol. Pathol. , 31 : 243 – 250 .
  • Sellers , R. S. , Mortan , D. , Bindu , M. , Roome , N. , Johnson , J. K. , Yano , B. L. , Perry , R. and Schafer , K. 2007 . Society of Toxicologic Pathology position paper: Organ weight recommendations for toxicology studies . Toxicol. Pathol. , 35 : 751 – 755 .
  • Schoeffner , D. J. , Warren , D. A. , Muralidara , S. , Bruckner , J. V. and Simmons , J. E. 1999 . Organ weights and fat volume in rats as a function of strain and age . J. Toxicol. Environ. Health A , 56 : 449 – 462 .
  • Thomas , R. S. , Lytle , W. E. , Keefe , T. J. , Constan , A. A. and Yang , R. S. 1996a . Incorporating Monte Carlo simulation into physiologically based pharmacokinetic models using advanced continuous simulation language (ACSL): A computational method . Fundam. Appl. Toxicol. , 31 : 19 – 28 .
  • Thomas , R. S. , Yang , R. S. , Morgan , D. G. , Moorman , M. P. , Kermani , H. R. , Sloane , R. A. , O'Connor , R. W. , Adkins , Jr, B. , Gargas , M. L. and Andersen , M. E. 1996b . PBPK modeling/Monte Carlo simulation of methylene chloride kinetic changes in mice in relation to age and acute, subchronic, and chronic inhalation exposure . Environ. Health Perspect. , 104 : 858 – 865 .
  • U.S. Environmental Protection Agency. 2006. Use of physiologically based pharmacokinetic (PBPK) models to quantify the impact of human age and interindividual differences in physiology and biochemistry pertinent to risk (Final report). U.S. EPA. EPA/600/R-06/014A. http://cfpub.epa.gov/ncea/cfm/recordisplay.cfm?deid=151384#Download (http://cfpub.epa.gov/ncea/cfm/recordisplay.cfm?deid=151384#Download) (Accessed: March 2006 ).
  • Yu , Z. H. 1998 . Asymmetrical testicular weights in mammals, birds, reptiles and amphibia. 1998 . Int. J. Androl. , 21 : 53 – 55 .

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