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Original Articles

A method for quantitative risk appraisal for pesticide risk assessments

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Pages 1-17 | Received 17 Jun 2016, Accepted 11 Aug 2016, Published online: 29 Nov 2016

References

  • Astrand, I. A. 1975. Uptake of solvents in the blood and tissues of man. A review. Scand. J. Work Environ. Health 1: 199–218.
  • Astrand, I., and Ovrum, P. 1976. Exposure to trichloroethylene. I. Uptake and distribution in man. Scand. J. Work Environ. Health 2: 199–211.
  • Auton, J. R., Ramsey, J. D., and Woollen, B. H. 1993. Modeling dermal pharmacokinetics using in vitro data. Part II. Fluazifop-butyl in man. Hum. Exp. Toxicol. 12: 207–213.
  • Barry, T. 2008. Development of sub-chronic air concentration estimates associated with a single fumigant application. Sacramento, CA: Environmental Monitoring, Department of Pesticide Regulation, California Environmental Protection Agency.
  • Boyd, J. D. 1987. Methyl parathion ambient air monitoring in Colusa and Sutter counties, May 1987, Corrected tables. http://cdpr.ca.gov/docs/emon/pubs/tac/tacpdfs/mepa_amb87.pdf
  • Burin, G. J., and Saunders, D. R. 1999. Addressing human variability in risk assessment—The robustness of the intraspecies uncertainty factor. Regul. Toxicol. Pharmacol. 30: 209–216.
  • California Department of Pesticide Regulation. 1994a. Mevinphos (Phosdrin): Risk characterization document. Medical Toxicology and Worker Health and Safety Branches, Department of Pesticide Regulation, California Environmental Protection Agency, Sacramento, CA.
  • California Department of Pesticide Regulation. 1994b. Estimation of exposure of persons in California to pesticide products that contain mevinphos. California Environmental Protection Agency, Department of Pesticide Regulation, Worker Health and Safety Branch, Sacramento, CA.
  • California Department of Pesticide Regulation. 1999a. Evaluation of methyl parathion as a toxic air contaminant. Part C. Human health assessment. California Environmental Protection Agency, Department of Pesticide Regulation, Medical Toxicology Branch, Sacramento, CA.
  • California Department of Pesticide Regulation. 1999b. Evaluation of methyl parathion as a toxic air contaminant. Part B. Exposure assessment. California Environmental Protection Agency, Department of Pesticide Regulation, Medical Toxicology Branch, Sacramento, CA.
  • California Department of Pesticide Regulation. 1999c. Benomyl risk characterization document. California Environmental Protection Agency, Department of Pesticide Regulation, Medical Toxicology Branch, Sacramento, CA.
  • California Department of Pesticide Regulation. 2004. Methyl parathion: Risk characterization document, occupational, ambient air and aggregate exposures. California Environmental Protection Agency, Department of Pesticide Regulation, Medical Toxicology Branch, Sacramento, CA.
  • California Department of Pesticide Regulation. 2008a. Methyl parathion: Risk characterization document, occupational, ambient air and aggregate exposures. Addendum to the 2004 Risk characterization document for methyl parathion dietary and ambient air exposures. California Environmental Protection Agency, Department of Pesticide Regulation, Medical Toxicology Branch, Sacramento, CA.
  • California Department of Pesticide Regulation. 2008b. Methyl parathion: Risk characterization document, occupational, ambient air and aggregate exposures. Addendum to the 2004 Risk Characterization Document for methyl parathion dietary and ambient air exposures. California Environmental Protection Agency, Department of Pesticide Regulation, Medical Toxicology Branch, Sacramento, CA.
  • California Department of Pesticide Regulation. 2010a. Estimation of exposure of persons in California to the pesticide products that contain methyl parathion. HS 1777. California Environmental Protection Agency, Department of Pesticide Regulation, Worker Health and Safety Branch, Sacramento, CA.
  • California Department of Pesticide Regulation. 2010b. Methyl iodide (iodomethane): Risk characterization document for inhalation exposure. California Environmental Protection Agency, Department of Pesticide Regulation, Medical Toxicology Branch, Sacramento, CA.
  • California Department of Pesticide Regulation. 2010c. Exposure assessment document for pesticide products containing methyl iodide. California Environmental Protection Agency, Department of Pesticide Regulation, Worker Health and Safety Branch, Human Health Assessment Program, Sacramento, CA.
  • California Department of Pesticide Regulation. 2010d. Methyl iodide (iodomethane) risk characterization document for inhalation exposure, Vol. 4—Part 1, Responses to scientific review committee comments. California Environmental Protection Agency, Department of Pesticide Regulation, Sacramento, CA.
  • California Department of Pesticide Regulation. 2010e. Methyl iodide (iodomethane) risk characterization document for inhalation exposure, Vol. 4—Part 2, Responses to public comments. California Environmental Protection Agency, Department of Pesticide Regulation, Sacramento, California.
  • Chamberlain, M. P., Lock, E.A ., Gaskell, B. A., and Reed, C. J. 1998. The role of glutathione S-transferase- and cytochrome P450-dependent metabolism in the olfactory toxicity of iodomethane in the rat. Arch. Toxicol. 72: 420–428.
  • CIA world factbook. 2016. Estimate of the prevalence of pregnancy in the US. https://www.cia.gov/library/publications/the-world-factbook/geos/us.html.
  • Cochran, R. C. 2001. Risk assessment for acute exposure to pesticides. In Handbook of pesticide toxicology, Vol. 1, Principles, 2nd ed., ed. R. I. Krieger, 691–705. New York, NY: Academic Press.
  • Cochran, R. C. 2002. Appraisal of the risks from non-occupational exposure to chlorpyrifos. Regul. Toxicol. Pharmacol. 35: 105–121.
  • Cochran, R. C., Formoli, T. A., Silva, M. H., Kellner, T. P., Lewis, C., and Pfeifer, K. 1996. Risks from occupational and dietary exposure to mevinphos. Rev. Environ. Contam. Toxicol. 146: 1–24.
  • Cochran, R. C., Formoli, T. A., Pfeifer, K. F., and Aldous, C. N. 1997. Characterization of risks associated with the use of molinate. Regul. Toxicol. Pharmacol. 25: 146–157.
  • Crofton, K. M., and Zhao, X. 1997. The ototoxicity of trichloroethylene: Extrapolation and relevance of high-concentration, short-duration animal exposure data. Fundam. Appl. Toxicol. 38: 101–106.
  • Davidson, I. W. F., Parker, J. C., and Beliles, R. P. 1986. Biological basis for extrapolation across mammalian species. Regul. Toxicol. Pharmacol. 6: 211–237.
  • Donahue, J. 1996. Revised policy on dermal absorption default for pesticides. HSM-96005. Worker Health and Safety Branch, Department of Pesticide Regulation, California Environmental Protection Agency, Sacramento, CA.
  • Dourson, M. L., and Stara, J. F. 1983. Regulatory history and experimental support of uncertainty (safety) factors. Regul. Toxicol. Pharmacol. 3: 224–238.
  • Dourson, M. L., and Stara, J. F. 1985. The conceptual basis of the acceptable daily intake. U.S. Environmental Protection Agency, Environmental Criteria and Assessment Office, Cincinnati, OH.
  • Dourson, M. E., Anderson, M. E., Erdreich, L. S., and MacGregor, J. A. 2001. Using human data to protect the public’s health. Regul. Toxicol. Pharmacol. 33: 234–256.
  • Eaton, D. L., and Klaassen, C. D. 2001. Principles of toxicology. In Casarett and Doull’s toxicology: The basic science of poisons, 6th ed., ed. C. D. Klaassen, M. O. Amdur, and J. Doull, 11–34. New York, NY: McGraw-Hill.
  • Federal Register. 1998. Protection of environment. Code of Federal Regulations 40, Parts 150–189, Office of the Register, National Archives and Records Administration. Washington, DC: U.S. Government Printing Office.
  • Food Quality Protection Act (FQPA) of 1996. 1996. U.S. Congress, Public Law No. 104–170, 110 Stat. 1489.
  • Frank, J. 2009. Method for calculating short-term exposure estimates. HSM-09004. Sacramento, CA: Worker Health & Safety Branch, Department of Pesticide Regulation, California Environmental Protection Agency. February 13. http://www.cdpr.ca.gov/docs/whs/memo/hsm09004.pdf
  • Franklin, C. A., Fenske, R. A., Greenhalgh, R., Mathieu, L., Denley, H. V., Leffingwell, J. T., and Spear, R. C. 1981. Correlation of urinary pesticide metabolite excretion with estimated dermal contact in the course of occupational exposure to Guthion. J. Toxicol. Environ. Health 7: 715–731.
  • Gammon, D., Liu, A., Chandrasekaran, A., and El Naggar, S. 2015. The pharmacokinetic properties of bifenthrin in the rat following multiple routes of exposure. Pestic. Manage. Sci. 71: 835–841.
  • Gansewendt, B., Xu, D., Foest, U., Hallier, E., Bolt, H. M., and Peter, H. 1991. DNA binding of iodomethane in male and female F344 rats. Carcinogenesis 12: 463–467.
  • Gargas, M. L., and Anderson, M. E. 1989. Determining kinetic constants of chlorinated ethane metabolism in the rat from rates of exhalation. Toxicol. Appl. Pharmacol. 99: 344–353.
  • Gaylor, D. W., Ryan, L., Krewski, D., and Zhu, Y. 1998. Procedures for calculating benchmark doses for health risk assessment. Regul. Toxicol. Pharmacol. 28:150–164
  • Ginevan, M. E., and Splitstone, D. E. 2002. Bootstrap upper bounds for the arithmetic mean of right-skewed data, and the use of censored data. Environmetrics 13: 453–464.
  • Jenkins, P., Phillips, T., Mulberg, E., and Hui, S. 1992. Activity patterns of Californians: Use of and proximity to indoor pollutant sources. Atmos. Environ. 26A: 2141–2148.
  • Kodell, R., Gaylor, D., and Chen, J. 1987. Using average lifetime dose rate for intermittent exposures to carcinogens. Risk Anal. 7: 339–345.
  • Kromhout H., and Vermeulen R. 2001.Temporal, personal and spatial variability in dermal exposure. Ann. Occup. Hyg. 45:257–273.
  • Maddy, K. T., Winter, C., Cepello, S., and Scot, A. 1981. Monitoring of potential occupational exposure of mixers/loaders, pilots, and flaggers during application of Phosdrin (mevinphos) in Monterey County in 1981. Worker Health and Safety Branch, California Department of Food and Agriculture, Sacramento, CA. HS–876.
  • Morgan, D. J., and Morgan, A. 1967. Studies on the retention and metabolism of inhaled methyl iodide- I. Retention of inhaled methyl iodide. Health Phys. 13: 1055–1065.
  • Morrison, P. F. 1987. Effects of time-variant exposure on toxic substance response. Environ. Health Perspect. 74: 133–140.
  • Murdoch, D. J., and Krewski, D. 1988. Carcinogenic risk assessment with time-dependent exposure patterns. Risk Anal. 8: 521–530.
  • Murdoch, D. J., Krewski, D., and Wargo, J. 1992. Cancer risk assessment with intermittent exposure. Risk Anal. 12: 569–577.
  • National Research Council. 1983. Risk assessment in the federal government: Managing the process. Washington, DC: National Academy Press.
  • O’Neil, M. J., ed. 2013. The Merck index: An encyclopedia of chemicals, drugs, and biologicals, 15th ed. Royal Society of Chemistry, Cambridge, UK.
  • Oshima, R. J., Neher, L. A., Mischke, T. M., Weaver, D. J., and Leifson, O. S. 1981. A characterization of sequential aerial malathion applications in the Santa Clara Valley of California, 1981. EH-82-01. Sacramento, CA: Environmental Hazards Assessment Program, Environmental Monitoring and Pest Management, Department of Food and Agriculture. http://www.cdpr.ca.gov/docs/emon/pubs/ehapreps/eh8201.pdf
  • Oshita, C. M., Schneider, F. A., and Margetich, S. 1988. An exposure study of mixer/loaders and applicators using oxydemeton-methyl (Metasystox-R) in the Salinas and Santa Maria valleys of California in 1986. HS–1398. Sacramento, CA: Worker Health and Safety Branch, Department of Pesticide Regulation, California Environmental Protection Agency.
  • Phillips, T. J., Jenkins, P. L., and Mulberg, E. J. 1991. Children in California: Activity patterns and presence of pollutant sources. California Resources Board, Sacramento, CA.
  • Powell, S. 2003. Why Worker Health and Safety Branch uses arithmetic means in exposure assessment. HSM-03022. Sacramento, CA: Worker Health and Safety Branch, Department of Pesticide Regulation, California Environmental Protection Agency, September 22.
  • Powell, S. 2006. Estimating residential mobility for the assessment of lifetime exposure to 1,3-dichloropropene. Worker Health and Safety Branch, California Department of Pesticide Regulation, Sacramento, CA, HSM–06015.
  • Powell, S. 2007. Recommended method for approximating confidence limits for upper bound and mean exposure estimates from the Pesticide Handlers Exposure Database (PHED) to replace the method of HSM-02037. Memorandum from Sally Powell to Joseph Frank, September 20. Sacramento, CA: Worker Health and Safety Branch, Department of Pesticide Regulation, California Environmental Protection Agency.
  • Reed, C. J., Gaskell, B. A., Banger, K. K., and Lock, E. A. 1995. Olfactory toxicity of methyl iodide in the rat. Arch. Toxicol. 70: 51–56.
  • Ross, J. H., Driver, J. H., Cochran, R. C., Thongsinthusak, T., and Krieger, R. I. 2001. Could pesticide toxicology studies be more relevant to occupational risk assessment? Ann. Occup. Hyg. 45: S5–S17.
  • Ross, J. H., Driver, J. H., Lunchick, C., Wible, C., and Selman, F. 2006. Pesticide exposure monitoring databases in applied risk analysis. Rev. Environ. Contam. Toxicol. 186: 107–132.
  • Sankaran, G., Lopez, T., Ries, S., Ross, J., Vega, H., Eastmond, D. A., and Krieger, R. I., 2015. Latex rubber gloves as a sampling dosimeter using a novel surrogate sampling device. J. Toxicol. Environ. Health A 78: 1094–1104.
  • Seiber, J. N., McChesney, M. M., Woodrow, J. E., and Shibamoto, T. L. 1987. Pilot analysis of methyl parathion in air. Final report to the Air Resources Board. Contract number A5-169-43. University of California Davis, Davis, CA.
  • Segawa, R. T., Sitts, J. A., White, J. H., Marade, S. J., and Powell, S. J. 1991. Environmental monitoring of malathion aerial applications used to eradicate Mediterranean fruit flies in Southern California, 1990. California Department of Food and Agriculture, Environmental Hazards Assessment Program, Sacramento, CA.
  • Shirota, F. N., Nagasawa, H. T., Kwon, C. H., and Demaster, E. G. 1984. N-Acetylcyanamide, the major urinary metabolite of cyanamide in rat, rabbit, dog, and man. Drug Metab. Dispos. 12: 337–344.
  • Spencer, J. R., Sanborn, J. R., Hernandez, B. Z., Krieger, R. I., Margetich, S. S., and Schneider, F. A. 1995. Long vs. short monitoring intervals for peach harvesters exposed to foliar azinphos-methyl residues. Toxicol. Lett. 78: 17–24.
  • Takegawa, K., Mitsumori, K., Onodera, H., Shimo, T., Kitaura, K., Yashuhara, K., Hirose, M., and Takahashi, M. 2000. Studies on the carcinogenicity of potassium iodide in F344 rats. Food Chem. Toxicol. 38: 773–781.
  • Tsuji, K. 1991. Reduction of pesticide toxicity by formulation. In Pesticides and the future: Toxicological studies of risk and benefit, ed. E. Hodgson, R. M. Rae, and N. Motoyama, 317–327. Raleigh, NC: North Carolina State University.
  • Ulman, E. A., Compton, D., and Kochanek, J. 2008. Measuring food and water intake in rats and mice. ALN Magazine, October, pp 17–20. www.alnmag.com.
  • U.S. Environmental Protection Agency. 1986. Human variability in susceptibility to toxic chemicals—Noncarcinogens. 600/8-86-033. NTIS PB87-101242/AS.
  • U.S. Environmental Protection Agency. 1991. Guidelines for developmental toxicity risk assessment. CFR 56 (No. 234): 63798-63826. December 5.
  • U.S. Environmental Protection Agency. 1992. Guidelines for exposure assessment; Notice. EPA/600/Z-92/001. Washington, DC: U.S. Environmental Protection Agency\.
  • U.S. Environmental Protection Agency. 1993. Protection of stratospheric ozone. Fed. Reg. 58(51): 15014–15049.
  • U.S. Environmental Protection Agency. 1998a. OPPTS harmonized guidelines. Series 870 Health effects test guidelines—Final guidelines. August. http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series
  • U.S. Environmental Protection Agency. 1998b. Hazard assessment of the organophosphates (http://www.epa.gov/pesticides/op/methyl_parathion/mp_09.pdf). Hazard Identification Assessment Review Committee Report. Office of Pesticide Programs, Health Effects Division, U.S. EPA, Washington, DC.
  • U.S. Environmental Protection Agency. 1998c. Assessment of thyroid follicular cell tumors. Office of Pesticide Programs and Office of Research and Development. EPA/630/R-97/002. March. U.S. EPA, Washington, DC.
  • U.S. Environmental Protection Agency. 1999. Human health risk assessment—Methyl parathion. Office of Pesticide Programs. Health Effects Division, U.S. Environmental Protection Agency. Washington, DC.
  • U.S. Environmental Protection Agency. 2005. Guidelines for carcinogen risk assessment. Fed. Reg. 70: 17765–17817.
  • U.S. Environmental Protection Agency. 2006a. Interim reregistration eligibility decision for methyl parathion. Case no. 0153.Office of Prevention, Pesticides and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC.
  • U.S. Environmental Protection Agency. 2006b. Iodomethane: Revised HED human health risk assessment; DP barcode: D32580, PC code: 000011. Memorandum from Elizabeth Mendez to Mary Waller, January 5. Office of Prevention, Pesticides and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC.
  • U.S. Environmental Protection Agency. 2011. Revisions to EPA’s rule on protections for subjects in human research involving pesticides. Fed. Reg. 76(22): 5735–5755.
  • U.S. Environmental Protection Agency. 2014a. Chlorpyrifos. Revised human health risk assessment for registration review. DP barcode: 424485, PC code: 059101. Memorandum from Danette Drew, Rochelle Bohaty, Cecilia Tan, thru: Michael Metzger and Dana Vogel, to: Tom Myers and Joel Wolf, December 29. Office of Prevention, Pesticides and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC.
  • U.S. Environmental Protection Agency. 2014b. Chlorpyrifos: Updated occupational and residential exposure assessment for registration review. DP barcode: 424484, PC code: 059101. Memorandum from Wade Britton, thru: Michael Metzger and Kelly O’Rourke, to: Kevin Costello and Joel Wolf, December 29. Office of Prevention, Pesticides and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC.
  • van Hemmen, J. J. 1992. Estimating worker exposure for pesticide registration. Rev. Environ. Contam. Toxicol. 128: 43–54.
  • Wester, R. C., Noonan, P. K., and Maibach, H. I. 1977. Frequency of application on percutaneous absorption of hydrocortisone. Arch. Dermatol. 113: 620–622.
  • Wester, R. C., Noonan, P. K., and Maibach, H. I. 1980. Variations in percutaneous absorption of testosterone in the rhesus monkey due to anatomic site of application and frequency of application. Arch. Dermatol. Res. 267: 229–235.
  • Wester R. C., and Maibach, H. I. 1993. Animal models for percutaneous absorption. In Health risk assessment: Dermal and inhalation exposure and absorption of toxicants, ed. R. G. M. Wang, J. B. Knaak, and M. I. Maibach, 89–103. Boca Raton, FL: CRC Press.
  • World Health Organization. 2008. Part I. Guidance document on evaluating and expressing uncertainty in exposure assessment. (IPCS harmonization project document; no. 6) I. International Programme on Chemical Safety. II. Series. NLM classification: QT 140. http://www.who.int/ipcs/methods/harmonization/areas/uncertainty%20.pdf
  • World Health Organization. 2014. Guidance document on evaluating and expressing uncertainty in hazard characterization. (IPCS harmonization project document; no. 11). I. International Programme on Chemical Safety. II. Series. NLM classification: QV 607. http://www.inchem.org/documents/harmproj/harmproj/harmproj11.pdf
  • Zielhuis, R. L., and van der Kreek F. W. 1979. The use of a safety factor in setting health based permissible levels for occupational exposure. Int. Arch. Occup. Environ. Health 42: 191–201.

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