258
Views
14
CrossRef citations to date
0
Altmetric
Original Articles

Nanoparticles-induced apoptosis of human airway epithelium is mediated by proNGF/p75NTR signaling

, , &
Pages 53-68 | Received 13 Jul 2016, Accepted 15 Sep 2016, Published online: 31 Jan 2017

References

  • ACGIH. 1992. Threshold limit values for chemical substances in the work environment. American Conference of Governmental Industrial Hygienists. Cincinnati, OH.
  • Barde, Y. A. 1994. Neurotrophins: A family of proteins supporting the survival of neurons. Prog. Clin. Biol. Res. 390: 45–56.
  • Barker, P. A., and E. M. Shooter. 1994. Disruption of NGF binding to the low affinity neurotrophin receptor p75LNTR reduces NGF binding to TrkA on PC12 cells. Neuron 13: 203–215.
  • Braun, A., M. Lommatzsch, G. R. Lewin, J. C. Virchow, and H. Renz. 1999. Neurotrophins: A link between airway inflammation and airway smooth muscle contractility in asthma? Int. Arch. Allergy Immunol. 118: 163–165.
  • Bruno, M. A., and A. C. Cuello. 2006. Activity-dependent release of precursor nerve growth factor, conversion to mature nerve growth factor, and its degradation by a protease cascade. Proc. Natl. Acad. Sci. USA 103: 6735–6740.
  • Chao, M. V. 1994. The p75 neurotrophin receptor. J. Neurobiol. 25: 1373–1385.
  • Chen, Y.-C, Y. H. Weng, Y. W. Chiu, and C. Y. Yang. 2015. Short-term effects of coarse particulate matter on hospital admissions for cardiovascular diseases: A case-crossover study in a tropical city. J. Toxicol. Environ. Health A 78: 1241–1253.
  • Costa, S., J. Ferreira, C. Silveira, C. Costa, D. Lopes, H. Relvas, C. Borrego, P. Roebeling, A. I. Miranda, and J. P. Teixeira. 2014. Integrating health on air quality assessment—Review report on health risks of two major European outdoor air pollutants: PM and NO₂. J. Toxicol. Environ. Health B 17: 307–340.
  • Curtis, R., K. M. Adryan, J. L. Stark, J. S. Park, D. L. Compton, G. Weskamp, L. J. Huber, M. V. Chao, R. Jaenisch, and K. F. Lee. 1995. Differential role of the low affinity neurotrophin receptor (p75) in retrograde axonal transport of the neurotrophins. Neuron 14: 1201–1211.
  • de Oliveira, B. F., A. P. Chacra, T. S. Frauches, A. Vallochi, and S. Hacon. 2014. A curated review of recent literature of biomarkers used for assessing air pollution exposures and effects in humans. J. Toxicol. Environ. Health B 17: 369–410.
  • Frade, J. M., and Y. A. Barde. 1998. Nerve growth factor: Two receptors, multiple functions. Bioessays 20: 137–145.
  • Gurr, J. R., A. S. Wang, C. H. Chen, and K. Y. Jan. 2005. Ultrafine titanium dioxide particles in the absence of photoactivation can induce oxidative damage to human bronchial epithelial cells. Toxicology 213: 66–73.
  • Hartmann, N. B., K. A. Jensen, A. Baun, K. Rasmussen, H. Rauscher, R. Tantra, D. Cupi, D. Gilliland, F. Pianella, and J. M. Riego Sintes. 2015. Techniques and protocols for dispersing nanoparticle powders in aqueous media—Is there a rationale for harmonization? J. Toxicol. Environ. Health B 18: 299–326.
  • Hempstead, B. L., D. Martin-Zanca, D. R. Kaplan, L. F. Parada, and M. V. Chao. 1991. High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor. Nature 350: 678–683.
  • Kermanizadeh, A., I. Gosens, L. MacCalman, H. Johnston, P. H. Danielsen, N. R. Jacobsen, A. G. Lenz, T. Fernandes, R. P. Schins, F. R. Cassee, H. Wallin, W. Kreyling, T. Stoeger, S. Loft, P. Møller, L. Tran, and V. Stone. 2016. A multilaboratory toxicological assessment of a panel of 10 engineered nanomaterials to human health—ENPRA project—The highlights, limitations, and current and future challenges. J. Toxicol. Environ. Health B 19: 1–28.
  • Lee, R., P. Kermani, K. K. Teng, and B. L. Hempstead. 2001. Regulation of cell survival by secreted pro-neurotrophins. Science 294:1945–1948.
  • Livak, K. J., and T. D. Schmittgen. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method. Methods 25: 402–408.
  • Majdan, M., G. S. Walsh, R. Aloyz, and F. D. Miller. 2001. TrkA mediates developmental sympathetic neuron survival in vivo by silencing an ongoing p75NTR-mediated death signal. J. Cell Biol. 155: 1275–1285.
  • Nel, A. 2005. Atmosphere. Air pollution-related illness: Effects of particles. Science 308: 804–806.
  • Oberdorster, G. 1996. Significance of particle parameters in the evaluation of exposure-dose-response relationships of inhaled particles. Inhal. Toxicol. 8(Suppl.): 73–89.
  • Oberdorster, G., V. Castranova, B. Asgharian, and P. Sayre. 2015. Inhalation exposure to carbon nanotubes (CNT) and carbon nanofibers (CNF): Methodology and dosimetry. J. Toxicol. Environ. Health B 18: 121–212.
  • Oberdorster, G., E. Oberdorster, and J. Oberdorster. 2005. Nanotoxicology: An emerging discipline evolving from studies of ultrafine particles. Environ, Health Perspect. 113: 823–839.
  • Okuda-Shimazaki, J., S. Takaku, K. Kanehira, S. Sonezaki, and A. Taniguchi. 2010. Effects of titanium dioxide nanoparticle aggregate size on gene expression. Int. J. Mol. Sci. 11: 2383–2392.
  • Olmedo, D. G., D. R. Tasat, M. B. Guglielmotti, and R. L. Cabrini. 2005. Effect of titanium dioxide on the oxidative metabolism of alveolar macrophages: An experimental study in rats. J. Biomed. Mater. Res. A 73: 142–149.
  • Othumpangat, S., L. F. Gibson, L. Samsell, and G. Piedimonte. 2009 NGF is an essential survival factor for bronchial epithelial cells during respiratory syncytial virus infection. PLoS ONE 4: e6444.
  • Phalen, R. F., M. J. Oldham, and A. E. Nel. 2006. Tracheobronchial particle dose considerations for in vitro toxicology studies. Toxicol. Sci. 92:126–132.
  • Pietropaoli, A. P., M. W. Frampton, R. W. Hyde, P. E. Morrow, G. Oberdorster, C. Cox, D. M. Speers, L. M. Frasier, D. C. Chalupa, L. S. Huang, and M. J. Utell. 2004. Pulmonary function, diffusing capacity, and inflammation in healthy and asthmatic subjects exposed to ultrafine particles. Inhal. Toxicol. 16(Suppl. 1): 59–72.
  • Pons, F., V. Freund, H. Kuissu, E. Mathieu, C. Olgart, and N. Frossard. 2001. Nerve growth factor secretion by human lung epithelial A549 cells in pro- and anti-inflammatory conditions. Eur. J. Pharmacol. 428: 365–369.
  • Robinson, R. C., C. Radziejewski, G. Spraggon, J. Greenwald, M. R. Kostura, L. D. Burtnick, D. I. Stuart, S. Choe, and E. Y. Jones. 1999. The structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding site. Protein Sci. 8: 2589–2597.
  • Scuri, M., B. T. Chen, V. Castranova, J. S. Reynolds, V. J. Johnson, L. Samsell, C. Walton, and G. Piedimonte. 2010a. Effects of titanium dioxide nanoparticle exposure on neuroimmune responses in rat airways. J. Toxicol. Environ. Health A 73: 1353–1369.
  • Scuri, M., L. Samsell, and G. Piedimonte. 2010b. The role of neurotrophins in inflammation and allergy. Inflamm. Allergy Drug Targets 9: 173–178.
  • Shvedova, A. A., T. Sager, A. Murray, E. Kisin, D. W Porter, S. S. Leonard, D. Schwegler-Berry, V. A. Robinson, and V. Castranova. 2007. Critical issues in the evaluation of possible effects resulting from airborn nanoparticles. In Nanotechnology: Characterization, dosing and health effects, 221–232. Philadelphia, PA: Informa Healthcare.
  • Snider, W. D., and I. Silos-Santiago. 1996. Dorsal root ganglion neurons require functional neurotrophin receptors for survival during development. Philos. Trans. R. Soc. Lond. B Biol. Sci. 351: 395–403.
  • Tsai, S. S., Y. H. Weng, Y. W. Chiu, and C. Y. Yang. 2015. Short-term effect of coarse particles on daily mortality rate in a tropical city, Kaohsiung, Taiwan. J. Toxicol. Environ. Health A 78:140–1420.
  • Tsuda, H., J. Xu, Y. Sakai, M. Futakuchi, and K. Fukamachi. 2009. Toxicology of engineered nanomaterials—A review of carcinogenic potential. Asian Pacific J. Cancer Prevent. 10: 975–980.
  • Verdi, J. M., S. J. Birren, C. F. Ibanez, H. Persson, D. R. Kaplan, M. Benedetti, M. V. Chao, and D. J. Anderson. 1994. p75LNGFR regulates Trk signal transduction and NGF-induced neuronal differentiation in MAH cells. Neuron 12: 733–745.
  • Verheij, M., R. Bose, X. H. Lin, B. Yao, W. D. Jarvis, S. Grant, M. J. Birrer, E. Szabo, L. I. Zon, J. M. Kyriakis, A. Haimovitz-Friedman, Z. Fuks, and R. N. Kolesnick. 1996. Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis. Nature 380: 75–79.
  • Xia, T., M. Kovochich, J. Brant, M. Hotze, J. Sempf, T. Oberley, C. Sioutas, J. I. Yeh, M. R. Wiesner, and A. E. Nel. 2006. Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm. Nano Lett. 6: 1794–1807.
  • Yazdi, A. S., G. Guarda, N. Riteau, S. K. Drexler, A. Tardivel, I. Couillin, and J. Tschopp. 2010. Nanoparticles activate the NLR pyrin domain containing 3 (NLRP3) inflammasome and cause pulmonary inflammation through release of IL-1alpha and IL-1beta. Proc. Natl. Acad. Sci. USA 107: 19449–19454.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.