Characterizing combined effects of antiestrogenic chemicals on vitellogenin production in rainbow trout (Oncorhynchus mykiss) hepatocytes

References

• Andersson, T., L. Förlin, J. Härdig, and Å. Larsson. 1988. Physiological disturbances in fish living in coastal water polluted with bleached kraft pulp mill effluents. Can. J. Fish. Aquat. Sci. 45:1525–1536.
   Web of Science ®Google Scholar
• Aranda, A., and A. Pascual. 2001. Nuclear hormone receptors and gene expression. Physiol. Rev. 81:1269–1304.
   PubMed Web of Science ®Google Scholar
• Arcaro, K. F., P. W. O’Keefe, Y. Yang, W. Clayton, and J. F. Gierthy. 1999. Antiestrogenicity of environmental polycyclic aromatic hydrocarbons in human breast cancer cells. Toxicology 133:115–127. doi:10.1016/S0300-483X(99)00018-9.
   PubMed Web of Science ®Google Scholar
• Arukwe, A., T. Celius, B. T. Walther, and A. Goksøyr. 2000. Effects of xenoestrogen treatment on zona radiata protein and vitellogenin expression in Atlantic salmon (Salmo salar). Aquat. Toxicol. 49:159–170. doi:10.1016/S0166-445X(99)00083-1.
   PubMed Web of Science ®Google Scholar
• Bemanian, V., R. Male, and A. Goksoyr. 2004. The aryl hydrocarbon receptor-mediated disruption of vitellogenin synthesis in the fish liver: cross-talk between AHR- and ER alpha-signalling pathways. Comp. Hepatol. 3:2. doi:10.1186/1476-5926-3-2.
   PubMedGoogle Scholar
• Brunnberg, S., K. Pettersson, E. Rydin, J. Matthews, A. Hanberg, and I. Pongratz. 2003. The basic helix–loop–helix–PAS protein ARNT functions as a potent coactivator of estrogen receptor-dependent transcription. Proc. Natl. Acad. Sci. 100:6517–6522.
   PubMed Web of Science ®Google Scholar
• Bugel, S. M., L. A. White, and K. R. Cooper. 2011. Decreased vitellogenin inducibility and 17β-estradiol levels correlated with reduced egg production in killifish (Fundulus heteroclitus) from Newark Bay, NJ. Aquat. Toxicol 105:1–12. doi:10.1016/j.aquatox.2011.03.013.
   PubMed Web of Science ®Google Scholar
• Casanova-Nakayama, A., M. Wenger, R. Burki, E. Eppler, A. Krasnov, and H. Segner. 2011. Endocrine disrupting compounds: can they target the immune system of fish? Mar. Pollut. Ecotoxicol. 63:412–416. doi:10.1016/j.marpolbul.2011.05.007.
   PubMed Web of Science ®Google Scholar
• Celius, T., J. B. Matthews, J. P. Giesy, and T. R. Zacharewski. 2000. Quantification of rainbow trout (Oncorhynchus mykiss) zona radiata and vitellogenin mRNA levels using real-time PCR after in vivo treatment with estradiol-17β or α-zearalenol. J. Steroid Biochem. Mol. Biol. 75:109–119. doi:10.1016/S0960-0760(00)00165-5.
   PubMed Web of Science ®Google Scholar
• Dobrzycka, K., S. Townson, S. Jiang, and S. Oesterreich. 2003. Estrogen receptor corepressors - a role in human breast cancer? Endocr. Relat. Cancer 10:517–536.
   PubMed Web of Science ®Google Scholar
• Ebright, R. H., J. R. Wong, and L. B. Chen. 1986. Binding of 2-hydroxybenzo (a) pyrene to estrogen receptors in rat cytosol. Cancer Res. 46:2349–2351.
   PubMed Web of Science ®Google Scholar
• Filby, A. L., and C. R. Tyler. 2005. Molecular characterization of estrogen receptors 1, 2a, and 2b and their tissue and ontogenic expression profiles in fathead minnow (Pimephales promelas). Biol. Reprod. 73:648–662. doi:10.1095/biolreprod.105.039701.
   PubMed Web of Science ®Google Scholar
• Gräns, J., B. Wassmur, and M. C. Celander. 2010. One-way inhibiting cross-talk between aryl hydrocarbon receptor (AhR) and estrogen receptor (ER) signaling in primary cultures of rainbow trout hepatocytes. Aquat. Toxicol. 100:263–270.
   PubMed Web of Science ®Google Scholar
• Grung, M., R. Lichtenthaler, M. Ahel, K.-E. Tollefsen, K. Langford, and K. V. Thomas. 2007. Effects-directed analysis of organic toxicants in wastewater effluent from Zagreb, Croatia. Chemosphere 67:108–120. doi:10.1016/j.chemosphere.2006.09.021.
   PubMed Web of Science ®Google Scholar
• Gu, Y.-Z., J. B. Hogenesch, and C. A. Bradfield. 2000. The PAS superfamily: sensors of environmental and developmental signals. Annu. Rev. Pharmacol. Toxicol. 40:519–561.
   PubMed Web of Science ®Google Scholar
• Hoffmann, J., S. Torontali, R. Thomason, D. Lee, J. Brill, B. Price, G. Carr, and D. Versteeg. 2006. Hepatic gene expression profiling using Genechips in zebrafish exposed to 17α-ethynylestradiol. Aquat. Toxicol. 79:233–246.
   PubMed Web of Science ®Google Scholar
• Hultman, M., Y. Song, and K. Tollefsen. 2015a. 17α-Ethinylestradiol (EE2) effect on global gene expression in primary rainbow trout (Oncorhynchus mykiss) hepatocytes. Aquat. Toxicol. 169:90–104.
   PubMed Web of Science ®Google Scholar
• Hultman, M. T., J. T. Rundberget, and K. E. Tollefsen. 2015b. Evaluation of the sensitivity, responsiveness and reproducibility of primary rainbow trout hepatocyte vitellogenin expression as a screening assay for estrogen mimics. Aquat. Toxicol. 159:233–244. doi:10.1016/j.aquatox.2014.12.013.
   PubMed Web of Science ®Google Scholar
• Hyllner, S., D. Oppen-Berntsen, J. Helvik, B. T. Walther, and C. Haux. 1991. Oestradiol-17β induces the major vitelline envelope proteins in both sexes in teleosts. J. Endocrinol. 131:229–236.
   PubMed Web of Science ®Google Scholar
• Kavlock, R. J., and G. T. Ankley. 1996. A Perspective on the risk assessment process for endocrine-disruptive effects on wildlife and human health. Risk Anal. 16:731–739. doi:10.1111/j.1539-6924.1996.tb00824.x.
   PubMed Web of Science ®Google Scholar
• King Heiden, T., M. J. Carvan, and R. J. Hutz. 2006. Inhibition of follicular development, vitellogenesis, and serum 17β-estradiol concentrations in zebrafish following chronic, sublethal dietary exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol. Sci. 90:490–499. doi:10.1093/toxsci/kfj085.
   PubMed Web of Science ®Google Scholar
• Lai, K. P., M. H. Wong, and C. K. C. Wong. 2004. Modulation of AhR-mediated CYP1A1 mRNA and EROD activities by 17β-estradiol and dexamethasone in TCDD-induced H411E cells. Toxicol. Sci. 78:41–49. doi:10.1093/toxsci/kfh045.
   PubMed Web of Science ®Google Scholar
• Li, J., D. Ma, Y. Lin, J. Fu, and A. Zhang. 2014. An exploration of the estrogen receptor transcription activity of capsaicin analogues via an integrated approach based on in silico prediction and in vitro assays. Toxicol. Lett. 227:179–188. doi:10.1016/j.toxlet.2014.04.007.
   PubMed Web of Science ®Google Scholar
• Long, W. P., M. Pray-Grant, J. C. Tsai, and G. H. Perdew. 1998. Protein kinase C activity is required for aryl hydrocarbon receptor pathway-mediated signal transduction. Mol. Pharmacol. 53:691–700.
   PubMed Web of Science ®Google Scholar
• Macgregor, J. I., and V. C. Jordan. 1998. Basic guide to the mechanisms of antiestrogen action. Pharmacol. Rev. 50:151–196.
   PubMed Web of Science ®Google Scholar
• Masuo, Y., and M. Ishido. 2011. Neurotoxicity of endocrine disruptors: possible involvement in brain development and neurodegeneration. J. Toxicol. Environ. Health B 14:346–369.
   PubMed Web of Science ®Google Scholar
• Matthews, J., and J.-Å. Gustafsson. 2003. Estrogen signaling: A subtle balance between ERα and ERβ. Mol. Interv. 3:281.
   PubMedGoogle Scholar
• Matthews, J., and J.-Å. Gustafsson. 2006. Estrogen receptor and aryl hydrocarbon receptor signaling pathways. Nucl. Recept. Signal. 4. doi:10.1621/nrs.04016.
   Google Scholar
• Mortensen, A., C. C. Tolfsen, and A. Arukwe. 2006. Gene expression patterns in estrogen (nonylphenol) and aryl hydrocarbon receptor agonists (PCB-77) interaction using rainbow trout (Oncorhynchus mykiss) primary hepatocyte culture. J. Toxicol. Environ. Health A 69:1–19.
   PubMed Web of Science ®Google Scholar
• Mortensen, A. S., and A. Arukwe. 2007. Targeted salmon gene array (SalArray): A toxicogenomic tool for gene expression profiling of interactions between estrogen and aryl hydrocarbon receptor signalling pathways. Chem. Res. Toxicol. 20:474–488.
   PubMed Web of Science ®Google Scholar
• Mortensen, A.S. and A. Arukwe. 2007b. Effects of 17α-ethynylestradiol on hormonal responses and xenobiotic biotransformation system of Atlantic salmon (Salmo salar). Aquatic toxicology, 85(2):113–123.
   PubMed Web of Science ®Google Scholar
• Mortensen, A. S., and A. Arukwe. 2008. Activation of estrogen receptor signaling by the dioxin-like aryl hydrocarbon receptor agonist, 3, 3′, 4, 4′, 5-pentachlorobiphenyl (PCB126) in salmon in vitro system. Toxicol. Appl. Pharmacol. 227:313–324.
   PubMed Web of Science ®Google Scholar
• Munn, S., and M. Goumenou 2013. Key scientific issues relevant to the identification and characterisation of endocrine disrupting substances report of the endocrine disrupters expert advisory group. Institute for Health and Consumer Protection (ISPRA).
   Google Scholar
• Nagler, J. J., T. Cavileer, J. Sullivan, D. G. Cyr, and C. Rexroad. 2007. The complete nuclear estrogen receptor family in the rainbow trout: discovery of the novel ERα2 and both ERβ isoforms. Gene 392:164–173.
   PubMed Web of Science ®Google Scholar
• Navas, J. M., and H. Segner. 2000. Antiestrogenicity of β-naphthoflavone and PAHs in cultured rainbow trout hepatocytes: evidence for a role of the aryl hydrocarbon receptor. Aquat. Toxicol. 51:79–92. doi:10.1016/S0166-445X(00)00100-4.
   PubMed Web of Science ®Google Scholar
• Navas, J.M. and H. Segner. 2001. Estrogen-mediated suppression of cytochrome P4501A (CYP1A) expression in rainbow trout hepatocytes: role of estrogen receptor. Chemico-biological interactions, 138(3):285–298.
   PubMed Web of Science ®Google Scholar
• Navas, J. M., and H. Segner. 2006. Vitellogenin synthesis in primary cultures of fish liver cells as endpoint for in vitro screening of the (anti) estrogenic activity of chemical substances. Aquat. Toxicol. 80:1–22.
   PubMed Web of Science ®Google Scholar
• Ohtake, F., K. Takeyama, T. Matsumoto, H. Kitagawa, Y. Yamamoto, K. Nohara, C. Tohyama, A. Krust, J. Mimura, and P. Chambon. 2003. Modulation of oestrogen receptor signalling by association with the activated dioxin receptor. Nature 423:545–550.
   PubMed Web of Science ®Google Scholar
• Pajor, A. M., J. J. Stegeman, P. Thomas, and B. R. Woodin. 1990. Feminization of the hepatic microsomal cytochrome P? 450 system in brook trout by estradiol, testosterone, and pituitary factors. J. Exp. Zool. 253:51–60.
   PubMedGoogle Scholar
• Pedersen, R. T., and E. M. Hill. 2000. Biotransformation of the xenoestrogen 4-tert-octylphenol in hepatocytes of rainbow trout (Oncorhynchus mykiss). Xenobiotica 30:867–879. doi:10.1080/004982500433291.
   PubMed Web of Science ®Google Scholar
• Petersen, K., and K. E. Tollefsen. 2011. Assessing combined toxicity of estrogen receptor agonists in a primary culture of rainbow trout (Oncorhynchus mykiss) hepatocytes. Aquat. Toxicol. 101:186–195.
   PubMed Web of Science ®Google Scholar
• Petersen, K., and K. E. Tollefsen. 2012. Combined effects of oestrogen receptor antagonists on in vitro vitellogenesis. Aquat. Toxicol. 112:46–53.
   PubMed Web of Science ®Google Scholar
• Pfaffl, M. W. 2001. A new mathematical model for relative quantification in real-time RT–PCR. Nucl Acids Res 29:2002–2007. doi:10.1093/nar/29.9.e45.
   Web of Science ®Google Scholar
• Rankouhi, T. R., J. Sanderson, I. Van Holsteijn, C. Van Leeuwen, A. Van Vethaak, and M. Van Den Berg. 2004. Effects of natural and synthetic estrogens and various environmental contaminants on vitellogenesis in fish primary hepatocytes: comparison of bream (Abramis brama) and carp (Cyprinus carpio). Toxicol. Sci. 81:90–102.
   PubMed Web of Science ®Google Scholar
• Rüegg, J., E. Swedenborg, D. Wahlström, A. Escande, P. Balaguer, K. Pettersson, and I. Pongratz. 2008. The transcription factor aryl hydrocarbon receptor nuclear translocator functions as an estrogen receptor β-selective coactivator, and its recruitment to alternative pathways mediates antiestrogenic effects of dioxin. Mol. Endocrinol. 22:304–316.
   PubMed Web of Science ®Google Scholar
• Safe, S., and M. Wormke. 2003. Inhibitory aryl hydrocarbon receptor-estrogen receptor α cross-talk and mechanisms of action. Chem. Res. Toxicol. 16:807–816.
   PubMed Web of Science ®Google Scholar
• Scornaienchi, M. L., C. Thornton, K. L. Willett, and J. Y. Wilson. 2010. Cytochrome P450-mediated 17β-estradiol metabolism in zebrafish (Danio rerio). J. Endocrinol. 206:317–325.
   PubMed Web of Science ®Google Scholar
• Segner, H., and J. Cravedi. 2000. Metabolic activity in primary cultures of fish hepatocytes. Altern. Lab. Animal ATLA 29:251–257.
   Web of Science ®Google Scholar
• Shanle, E. K., and W. Xu. 2011. Endocrine disrupting chemicals targeting estrogen receptor signaling: identification and mechanisms of action. Chem. Res. Toxicol. 24:6–19. doi:10.1021/tx100231n.
   PubMed Web of Science ®Google Scholar
• Smeets, J. M., T. R. Rankouhi, K. M. Nichols, H. Komen, N. E. Kaminski, J. P. Giesy, and M. Van Den Berg. 1999. In vitro vitellogenin production by carp (Cyprinus carpio) hepatocytes as a screening method for determining (anti) estrogenic activity of xenobiotics. Toxicol. Appl. Pharmacol. 157:68–76.
   PubMed Web of Science ®Google Scholar
• Sumpter, J. P. 2005. Endocrine disrupters in the aquatic environment: an overview. Acta Hydrochim. Hydrobiol. 33:9–16. doi:10.1002/aheh.200400555.
   Google Scholar
• Sumpter, J. P., and S. Jobling. 1995. Vitellogenesis as a biomarker for estrogenic contamination of the aquatic environment. Environ. Health Persp. 103:173–178.
   PubMed Web of Science ®Google Scholar
• Swedenborg, E., and I. Pongratz. 2010. AhR and ARNT modulate ER signaling. Toxicology 268:132–138. doi:10.1016/j.tox.2009.09.007.
   PubMed Web of Science ®Google Scholar
• Tollefsen, K.-E., R. Mathisen, and J. Stenersen. 2003. Induction of vitellogenin synthesis in an Atlantic salmon (Salmo salar) hepatocyte culture: a sensitive in vitro bioassay for the oestrogenic and anti-oestrogenic activity of chemicals. Biomarkers 8:394–407.
   PubMed Web of Science ®Google Scholar
• Tran, D. Q., C. F. Ide, J. A. McLachlan, and S. F. Arnold. 1996. The anti-estrogenic activity of selected polynuclear aromatic hydrocarbons in yeast expressing human estrogen receptor. Biochem. Biophys. Res. Commun. 229:101–108.
   PubMed Web of Science ®Google Scholar
• Tyler, C. R., J. P. Sumpter, and N. R. Bromage. 1988. In vivo ovarian uptake and processing of vitellogenin in the rainbow trout. Salmo Gairdneri. J. Exp. Zool. 246:171–179. doi:10.1002/jez.1402460209.
   Web of Science ®Google Scholar
• Wu, Y.-L., X. Yang, Z. Ren, D. P. McDonnell, J. D. Norris, T. M. Willson, and G. L. Greene. 2005. Structural basis for an unexpected mode of SERM-mediated ER antagonism. Mol. Cell 18:413–424. doi:10.1016/j.molcel.2005.04.014.
   PubMed Web of Science ®Google Scholar
• Yoon, K., S.-J. Kwack, H. S. Kim, and B. M. Lee. 2014. Estrogenic endocrine-disrupting chemicals: molecular mechanisms of action on putative human diseases. J. Toxicol. Environ. Health B 17:127–174.
   PubMed Web of Science ®Google Scholar