Role of the gene Phlda1 in fenvalerate-induced apoptosis and testicular damage in Sprague-Dawley rats

References

• Ben Slima, A., Y. Chtourou, M. Barkallah, H. Fetoui, T. Boudawara, and R. Gdoura. 2017. Endocrine disrupting potential and reproductive dysfunction in male mice exposed to deltamethrin. Hum. Exp. Toxicol. 36:218–26. doi:10.1177/0960327116646617.
   PubMed Web of Science ®Google Scholar
• Bian, Q., L. C. Xu, S. L. Wang, Y. K. Xia, L. F. Tan, J. F. Chen, L. Song, H. C. Chang, and X. R. Wang. 2004. Study on the relation between occupational fenvalerate exposure and spermatozoa DNA damage of pesticide factory workers. Occup. Environ. Med. 61:999–1005. doi:10.1136/oem.2004.014597.
   PubMed Web of Science ®Google Scholar
• Borch, J., M. Dalgaard, and O. Ladefoged. 2005. Early testicular effects in rats perinatally exposed to DEHP in combination with DEHA-apoptotic assessment and immunohistochemical studies. Reprod. Toxicol 9:517–25. doi:10.1016/j.reprotox.2004.11.004.
   Google Scholar
• Chen, Y., M. Takikawa, S. Tsutsumi, Y. Yamaguchi, A. Okabe, S. M. Himada, T. Kawase, A. Sada, I. Ezawa, Y. Takano, et al. 2018. PHLDA1, another PHLDA family protein that inhibits Akt. Cancer Sci. 109:3532–42. doi:10.1111/cas.13796.
   PubMed Web of Science ®Google Scholar
• el-Demerdash, F. M., M. I. Yousef, F. S. Kedwany, and H. H. Baghdadi. 2004. Role of alpha-tocopherol and beta-carotene in ameliorating the fenvalerate-induced changes in oxidative stress, hemato-biochemical parameters, and semen quality of male rats. J. Environ. Sci. Health B 39:443–59.
   PubMed Web of Science ®Google Scholar
• Gomes, I., W. Xiong, T. Miki, and M. R. Rosner. 1999. A proline- and glutamine-rich protein promotes apoptosis in neuronal cells. J. Neurochem 73 612–22.
   PubMed Web of Science ®Google Scholar
• Guo, Y., O. Shen, J. Han, H. Duan, S. Yang, Z. Zhu, J. Tong, and J. Zhang. 2017. Circadian rhythm genes mediate fenvalerate-induced inhibition of testosterone synthesis in mouse Leydig cells. J. Toxicol. Environ. Health Part A 80:1314–20. doi:10.1080/15287394.2017.1384148.
   PubMed Web of Science ®Google Scholar
• Han, J., C. Ji, Y. Guo, R. Yan, T. Hong, Y. Dou, Y. An, S. Tao, F. Qin, J. Nie, et al. 2017. Mechanisms underlying melatonin-mediated prevention of fenvalerate-induced behavioral and oxidative toxicity in zebrafish. J. Toxicol. Environ. Health Part A 80:1331–41. doi:10.1080/15287394.2017.1384167.
   PubMed Web of Science ®Google Scholar
• Ichimura, T., M. Kawamura, and A. Mitani. 2003. Co-localized expression of FasL, Fas, Caspase-3 and apoptotic DNA fragmentation in mouse testis after oral exposure to di (2-ethylhexyl) phthalate. Toxicology 194:35–42. doi:10.1016/j.tox.2003.07.003.
   PubMed Web of Science ®Google Scholar
• Kastrati, I., E. Canestrari, and J. Frasor. 2015. PHLDA1 expression is controlled by an estrogen receptor-NFκB-miR-181 regulatory loop and is essential for formation of ER+ mammospheres. Oncogene 34:2309–16. doi:10.1038/onc.2014.180.
   PubMed Web of Science ®Google Scholar
• Liu, F., Z. L. Xu, X. J. Qian, W. Y. Qiu, and H. Huang. 2011. Expression of Hsf1, Hsf2, and Phlda1 in cells undergoing cryptorchid-induced apoptosis in rat testes. Mol. Reprod. Dev. 78:283–91. doi:10.1002/mrd.21304.
   PubMed Web of Science ®Google Scholar
• Mani, U., F. Islam, A. K. Prasad, P. Kumar, V. Suresh Kumar, B. K. Maji, and K. K. Dutta. 2002. Steroidogenic alterations in testes and sera of rats exposed to formulated fenvalerate by inhalation. Hum. Exp. Toxicol. 21:593–97. doi:10.1191/0960327102ht298oa.
   PubMed Web of Science ®Google Scholar
• Marchiori, A. C., D. A. Casolari, and M. A. Nagai. 2008. Transcriptional up-regulation of PHLDA1 by 17β-estradiol in MCF-7 breast cancer cells. Braz. J. Med. Biol. Res. 41:579–82. doi:10.1590/s0100-879x2008005000029.
   PubMed Web of Science ®Google Scholar
• McClusky, L. M., C. de Jager, and M. S. Bornman. 2007. Stage-related increase in the proportion of apoptotic germ cells and altered frequencies of stages in the spermatogenic cycle following gestational, lactational, and direct exposure of male rats to p-nonylphenol. Toxicol. Sci. 95:249–56. doi:10.1093/toxsci/kfl141.
   PubMed Web of Science ®Google Scholar
• Nagai, M. A. 2016. Pleckstrin homology-like domain, family A, member 1 (PHLDA1) and cancer. Biomed. Rep. 4:275–81. doi:10.3892/br.2016.580.
   PubMed Web of Science ®Google Scholar
• Nassr, A. C., A. C. Arena, F. C. Toledo, D. Z. Bissacot, C. D. Fernandez, A. L. Spinardi-Barbisan, P. W. Pires, and W. G. Kempinas. 2010. Effects of gestational and lactational fenvalerate exposure on immune and reproductive systems of male rats. J. Toxicol. Environ. Health Part A 73:952–64. doi:10.1080/15287391003751745.
   PubMed Web of Science ®Google Scholar
• Neef, R., M. A. Kuske, E. Pröls, and J. P. Johnson. 2002. Identification of the human PHLDA1/TDAG51 gene: Down-regulation in metastatic melanoma contributes to apoptosis resistance and growth deregulation. Cancer Res. 62:5920–29.
   PubMed Web of Science ®Google Scholar
• Park, C. G., S. Y. Lee, G. Kandala, S. Y. Lee, and Y. Choi. 1996. A novel gene product that couples TCR signaling to Fas (CD95) expression in activation-induced cell death 6. Immunity 4:583–91.
   PubMed Web of Science ®Google Scholar
• Saradha, B., S. Vaithinathan, and P. P. Mathur. 2009. Lindane induces testicular apoptotic in adult Wistar rats through the involvement of Fas–FasL and mitochondria-dependent pathways. Toxicology 255:131–39. doi:10.1016/j.tox.2008.10.016.
   PubMed Web of Science ®Google Scholar
• Sobarzo, C. M., L. Lustig, R. Ponzio, and B. Denduchis. 2006. Effect of di-(2-ethylhexyl) phthalate on N-cadherin and catenin protein expression in rat testis. Reprod. Toxicol 22:77–86. doi:10.1016/j.reprotox.2006.04.011.
   PubMed Web of Science ®Google Scholar
• Wang, B., J. J. Liu, Y. Wang, L. Fu, R. Shen, Z. Yu, H. Wang, Y. H. Chen, C. Zhang, X. H. Meng, et al. 2017. Maternal fenvalerate exposure induces fetal intrauterine growth restriction through disrupting placental thyroid hormone receptor signaling. Toxicol. Sci. 157:377–86. doi:10.1093/toxsci/kfx052.
   PubMed Web of Science ®Google Scholar
• Wang, J., F. Wang, J. Zhu, M. Song, J. An, and W. Li. 2018. Transcriptome profiling reveals PHLDA1 as a novel molecular marker for ischemic cardiomyopathy. J. Mol. Neurosci. 65:102–09. doi:10.1007/s12031-018-1066-6.
   PubMed Web of Science ®Google Scholar
• Wolansky, M. J., and R. Tornero-Velez. 2013. Critical consideration of the multiplicity of experimental and organismic determinants of pyrethroid neurotoxicity: A proof of concept. J. Toxicol. Environ. Health B 16:453–90. doi:10.1080/10937404.2013.853607.
   PubMed Web of Science ®Google Scholar
• Xia, Y., Q. Bian, L. Xu, S. Cheng, L. Song, J. Liu, W. Wu, S. Wang, and X. Wang. 2004. Genotoxic effects on human spermatozoa among pesticide factory workers exposed to fenvalerate. Toxicology 203:49–60. doi:10.1016/j.tox.2004.05.018.
   PubMed Web of Science ®Google Scholar
• Xu, Y. R., H. S. Dong, and W. X. Yang. 2016. Regulators in the apoptotic pathway during spermatogenesis: Killers or guards? Gene 582:97–111. doi:10.1016/j.gene.2016.02.007.
   PubMed Web of Science ®Google Scholar
• Ye, X., K. Xiong, and J. Liu. 2016. Comparative toxicity and bioaccumulation of fenvalerate and esfenvalerate to earthworm Eisenia fetida. J. Hazard. Mater. 310:82–88. doi:10.1016/j.jhazmat.2016.02.010.
   PubMed Web of Science ®Google Scholar
• Zhang, H., H. Wang, Q. Wang, X. F. Zhao, P. Liu, Y. L. Ji, H. Ning, T. Yu, C. Zhang, Y. Zhang, et al. 2010. Pubertal and early adult exposure to fenvalerate disrupts steroidogenesis and spermatogenesis in mice at adulthood. J. Appl. Toxicol. 30:369–77. doi:10.1002/jat.1507.
   PubMed Web of Science ®Google Scholar
• Zhang, J., Y. Hu, J. Guo, R. Pan, R. Shi, Y. Tian, Y. Zhou, and Y. Gao. 2018. Fenvalerate decreases semen quality in puberty rat through germ cell apoptosis. Andrologia 50:e13079. doi:10.1111/and.2018.50.issue-9.
   PubMed Web of Science ®Google Scholar
• Zhang, Q., Y. Zhang, J. Du, and M. Zhao. 2017. Environmentally relevant levels of lambda-cyhalothrin, fenvalerate, and permethrin cause developmental toxicity and disrupt endocrine system in zebrafish (Danio rerio) embryo. Chemosphere 185:1173–80. doi:10.1016/j.chemosphere.2017.07.091.
   PubMed Web of Science ®Google Scholar
• Zhao, X. F., Q. Wang, Y. L. Ji, H. Wang, P. Liu, C. Zhang, Y. Zhang, and D. X. Xu. 2011. Fenvalerate induces germ cell apoptosis in mouse testes through the Fas/FasL signaling pathway. Arch. Toxicol. 85:1101–08. doi:10.1007/s00204-011-0654-9.
   PubMed Web of Science ®Google Scholar