59
Views
48
CrossRef citations to date
0
Altmetric
Original Articles

Toxicity of abrin and ricin in mice and dogs

, , &
Pages 1073-1084 | Received 14 Jun 1979, Accepted 16 Jul 1979, Published online: 20 Oct 2009

References

  • Derenzini , M. , Benetti , E. , Marinozzi , V. and Stirpe , F. 1976 . Toxic effects of ricin. Studies on the pathogenesis of liver lesions . Virchows Arch. B , 20 : 15 – 28 .
  • Ehrlich , P. 1891, 1892, 1957 . The Collected Papers of Paul Ehrlich , vol 2 , 21 – 44 . New York : Pergamon .
  • Flexner , S. 1897 . The histological changes produced by ricin and abrin intoxications . J. Exp. Med. , 2 : 197 – 216 .
  • Fodstad , Ø . 1979 . “ Human gastointestinal cancer grown in nude mice used to test new chemotherapeutic agents ” . In Frontiers in Gastrointestinal Research , Edited by: van du Rees , L. vol. 5 , 71 – 80 . Basel : Karger .
  • Fodstad , Ø. and Pihl , A. 1978 . Effect of ricin and abrin on survival of L 1210 leukemic mice and on leukemic and normal bone marrow cells . Int. J. Cancer , 22 : 558 – 563 .
  • Fodstad , Ø. , Olsnes , S. and Pihl , A. 1976 . Toxicity, distribution, and elimination of the cancerostatic lectins abrin and ricin after parenteral injection into mice . Br. J. Cancer , 34 : 418 – 425 .
  • Fodstad , Ø. , Olsnes , S. and Pihl , A. 1977 . Inhibitory effect of abrin on the growth of transplantable murine tumors and of abrin on human cancer in nude mice . Cancer Res. , 37 : 4559 – 4567 .
  • Gundersen , S. and Fodstad , Ø. 1979 . Treatment of micrometastases from Lewis lung carcinoma with abrin and cyclophosphamide, given singly and in combination . Int. J. Cancer , 23 : 530 – 535 .
  • Lin , J.‐Y. , Tserng , K.‐Y. , Chen , C.‐C. , Lin , L.‐T. and Tung , T.‐C. 1970 . Abrin and ricin: New anti‐tumour substances . Nature (Lond.) , 227 : 292 – 293 .
  • McDowell , E. M. and Trump , B. F. 1976 . Histological fixatives suitable for diagnostic light and electron microscopy . Arch. Pathol. Lab. Med. , 100 : 405 – 414 .
  • Mollenhauer , H. 1964 . Plastic embedding for use in electron microscopy . Stain Technol. , 39 : 111 – 114 .
  • Morton , J. F. 1977 . “ Poisonous and injurious higher plants and fungi ” . In Forensic Medicine , Edited by: Tedeschi , C. G. , Eckert , W. G. and Tedeschi , L. G. vol. 3 , 1456 – 1567 . London : Saunders .
  • Mülller , F. 1899 . Beiträge zur Toxicologie des Ricins . Arch. Exp. Pathol. Pharmakol. , 42 : 302 – 322 .
  • Olsnes , S. and Pihl , A. 1973a . Different biological properties of the two constituent peptide chains of ricin, a toxic protein inhibiting protein synthesis . Biochemistry , 12 : 3121 – 3126 .
  • Olsnes , S. and Pihl , A. 1973b . Isolation and properties of abrin, a toxic protein inhibiting protein synthesis . Eur. J. Biochem. , 35 : 179 – 185 .
  • Olsnes , S. and Pihl , A. 1976 . “ Abrin, ricin and their associated agglutinins ” . In The Specificity and Action of Animal, Bacterial and Plant Toxins , Edited by: Cuatrecasas , P. 131 – 183 . London : Chapman & Hall .
  • Olsnes , S. and Pihl , A. 1978 . Abrin and ricin–two toxic lectins . Trends in Biochemical Sciences , 3 : 7 – 10 .
  • Pihl , A. , Fodstad , Ø. and Olsnes , S. Antitumor properties of the toxic lectins abrin and ricin . Proceedings of the 17th Annual Colloquium on Protides of the Biological Fluids . Brussels, New York. Pergamon . In press
  • Schein , P. S. , Davis , R. D. , Carter , S. , Newman , J. , Schein , D. R. and Rail , D. P. 1970 . The evaluation of anticancer drugs in dogs and monkeys for the prediction of qualitative toxicities in man . Clin. Pharmacol. Ther. , 11 : 3 – 40 .
  • Stillmark , H. 1888 . Uber Ricin, ein giftiges Ferment aus der Samen von Ricinus communis L und anderen Euphorbiaceen , Dorpat : Estonia . Dissertation

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.