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Original Articles

Influence of sulfur dioxide on metabolism and distribution of benzo [α] pyrene in isolated perfused rabbit lung

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Pages 1001-1024 | Received 11 Jun 1980, Accepted 12 Nov 1980, Published online: 20 Oct 2009

References

  • Andersen , I. , Lundguist , G. R. , Jensen , P. L. and Proctor , D. F. 1974 . Human response to controlled levels of sulfur dioxide . Arch. Environ. Health , 28 : 31 – 39 .
  • Autrup , H. , Harris , C. C. , Stoner , G. D. , Selkirk , J. K. , Schafer , P. W. and Trump , B. F. 1978 . Metabolism of (3H)benzo(a)pyrene by cultured human bronchus and cultured human pulmonary alveolar macrophages . Lab. Invest. , 38 (3) : 217 – 224 .
  • Badger , G. M. 1962 . Mode of formation of carcinogens in human environment . Natl. Cancer Inst. Monogr. , 9 : 1 – 16 .
  • Bingham , E. , Niemeier , R. W. and Dalbey , W. 1976a . Metabolism of environmental pollutants by isolated perfused lung . Fed. Proc. , 35 : 81 – 84 .
  • Bingham , E. , Niemeier , R. W. and Reid , J. B. 1976b . Multiple factors in carcinogenesis . Ann. N.Y. Acad. Sci. , 271 : 14 – 21 .
  • Bingham , E. , Warshawsky , D. and Niemeier , R. W. 1978 . “ Metabolism of benzo(a)pyrene in the isolated perfused rabbit lung following n‐dodecane inhalation ” . In Mechanisms of Tumor Promotion vol. 2 Carcinogenesis , Edited by: Slaga , T. J. , Sivak , A. and Boutwell , R. K. vol. 2 , 509 – 516 . New York : Raven .
  • Coffin , D. W. and Knelson , J. H. 1976 . Effects of sulfur dioxide and sulfate aerosol particles on human health . Ambio , 5 : 239 – 242 .
  • Cohen , G. M. and Moore , B. P. 1976 . Metabolism of (3H)benzo(a)pyrene by different portions of the respiratory tract . Biochem. Pharmacol. , 25 : 1623 – 1629 .
  • Cohen , G. M. , Moore , B. P. and Bridges , J. W. 1977 . Organic solvent soluble sulphate ester conjugates of monohydroxybenzo(a)pyrene . Biochem. Pharmacol. , 26 : 551 – 553 .
  • Creasia , D. A. , Poggenburg , J. K. Jr. and Nettesheim , P. 1976 . Elution of benzo(a)pyrene from carbon particles in the respiratory tract of mice . J. Toxicol. Environ. Health , 1 : 967 – 975 .
  • Eling , T. E. , Pickett , R. D. , Orton , T. C. and Anderson , M. W. 1975 . A study of the dynamics of imipramine accumulation in the isolated perfused rabbit lung . Drug Metab. Dispos. , 3 (5) : 389 – 399 .
  • Ellison , J. M. and Waller , R. E. 1978 . A review of sulphur oxides and particulate matter as air pollutants with particular reference to effects on health in the United Kingdom . Environ. Res. , 16 : 302 – 325 .
  • Harris , C. C. , Hsu , I. C. , Stoner , G. D. , Trump , B. F. and Selkirk , J. 1978 . Human pulmonary alveolar macrophages metabolise benzo(a)pyrene to proximate and ultimate mutagens . Nature (Lond.) , 272 : 633 – 634 .
  • Henry , M. C. and Kaufman , D. G. 1973 . Clearance of benzo(a)pyrene from hamster lungs after administration on coated particles . J. Natl. Cancer Inst. , 51 : 1961 – 1964 .
  • Henry , M. C. , Port , C. D. and Kaufman , D. G. 1975 . Importance of physical properties of benzo(a)pyrene‐ferric oxide mixtures in lung tumor induction . Cancer Res. , 35 : 207 – 217 .
  • Hidy , G. M. , Katz , J. L. and Mirabel , P. 1978 . Sulfate aerosol formation and growth in the stratosphere . Atmos. Environ. , 12 : 887 – 892 .
  • Husain , M. M. and Dehnen , W. 1978 . Effect of NO2 and SO2 inhalation on benzo(a)pyrene metabolism in rat lung . Arch. Toxicol. , 40 : 207 – 210 .
  • Intersociety Committee . 1972 . Methods of Air Sampling and Analysis, Tentative Method of Analysis for Sulfur Dioxide Content of the Atmosphere , 447 – 455 . Washington, D.C. : American Public Health Association .
  • Lang , K. F. , Buffleb , H. and Zander , M. 1963 . Pyrolysis of polynuclear aromatic hydrocarbons . Erdoel Kohle , 16 : 944 – 946 .
  • Laskin , S. , Kuschner , M. and Drew , R. T. 1970 . “ Studies in pulmonary carcinogenesis ” . In Inhalation Carcinogenesis , Edited by: Hanna , M. G. , Nettesheim , P. and Gilbert , J. R. 321 – 351 . USAEC Division of Technical Information . CONF‐691001
  • Liberti , A. , Brocco , D. and Possanzini , M. 1978 . Adsorption and oxidation of sulfur dioxide on particles . Atmos. Environ. , 12 : 255 – 261 .
  • Mass , M. and Kaufman , D. 1979 . Benzo(a)pyrene quinone metabolism in tracheal organ cultures . Biochem. Biophys. Res. Commun. , 38 : 885 – 892 .
  • McGovern , J. P. , Lubaway , W. C. and Kostanbauder , W. B. 1976 . Uptake and metabolism of nicotine by the isolated perfused rabbit lung . J. Pharmacol. Exp. Ther. , 199 : 198 – 207 .
  • Meehan , T. , Straub , K. and Calvin , M. 1976 . Elucidation of hydrocarbon structure in enzyme‐catalyzed benzo(a)pyrene‐poly G covalent complex . Proc. Natl. Acad. Sci. U.S.A. , 73 : 1437 – 1441 .
  • Miller , D. F. 1978 . Precursor effects on SO2 oxidation . Atmos. Environ. , 12 : 273 – 280 .
  • Moore , B. P. and Cohen , G. M. 1978 . Metabolism of benzo(a)pyrene and its major metabolites to ethyl acetate‐soluble and water‐soluble metabolites by cultured rodent trachea . Cancer Res. , 38 : 3066 – 3075 .
  • NAS . 1972 . Paniculate Polycyclic Organic Matter , Washington, D.C. : National Academy of Sciences .
  • Natusch , D. F. S. 1978 . Potentially carcinogenic species emitted to the atmosphere by fossil fueled power plants . Environ. Health Perspect , 22 : 79 – 90 .
  • Newhouse , M. T. , Dolovich , M. , Obminski , G. and Wolff , R. K. 1978 . Effects of TLV levels of SO2 and H2SO4 on bronchial clearance in exercising man . Arch. Environ. Health , 33 : 24 – 32 .
  • Niemeier , R. W. 1976 . Isolated perfused rabbit lung: A critical appraisal . Environ. Health Perspect. , 16 : 67 – 71 .
  • Niemeier , R. W. and Bingham , E. 1972 . An isolated perfused lung preparation for metabolic studies . Life Sci. , 11 : 807 – 820 .
  • Niemeier , R. W. , Warshawsky , D. and Bingham , E. 1977 . Influence of pretreatment on B(a)P metabolism in isolated perfused lung . Toxicol. Appl. Pharmacol. , 41 : 185
  • Saffiotti , U. 1970 . “ Experimental respiratory tract carcinogenesis and its relation to inhalation exposures ” . In Inhalation Carcinogenesis , Edited by: Hanna , M. G. , Nettesheim , P. and Gilbert , J. R. 27 – 54 . USAEC Division of Technical Information . CONF‐691001
  • Saltzman , B. E. , Burg , W. R. and Ramaswamy , G. 1971 . Performance of permeation tubes as standard gas sources . Environ. Sci. Technol. , 5 : 1121 – 1128 .
  • Shabad , L. M. 1971 . Dose‐response studies in experimentally induced lung tumors . Environ. Res. , 4 : 305 – 315 .
  • Smith , B. R. , Maguire , J. H. , Ball , L. M. and Bend , J. R. 1978a . Pulmonary metabolism of epoxides . Fed. Proc. , 37 : 2480 – 2484 .
  • Smith , B. R. , Philpot , R. M. and Bend , J. R. 1978b . Metabolism of benzo(a)pyrene by the isolated perfused rabbit lung . Drug. Metab. Dispos. , 6 : 425 – 431 .
  • Tartarelli , R. , Davini , P. , Morelli , F. and Corsi , P. 1978 . Interactions between SO2 and carbonaceous particulates . Atmos. Environ. , 12 : 289 – 293 .
  • Vahakangas , K. , Nevassari , K. , Pelkonen , O. and Karki , N. T. 1977 . The metabolism of benzo(a)pyrene in isolated perfused lungs from variously‐treated rats . Acta Pharmacol. Toxicol. , 41 : 129 – 140 .
  • Von Nieding , G. 1978 . Possible mutagenic properties and carcinogenic action of the irritant gaseous pollutants NO2, O3, and SO2 . Environ. Health Perspect. , 22 : 91 – 92 .
  • Warshawsky , D. , Niemeier , R. W. and Bingham , E. 1978 . “ Influence of particulates on metabolism of benzo(a)pyrene in the isolated perfused lung ” . In Carcinogenesis , Edited by: Jones , R. W. and Freudenthal , R. I. vol. 3 , 347 – 360 . New York : Raven .
  • West , P. W. and Gaeke , G. C. 1956 . Fixation of sulfur dioxide as disulfitomercurate(ll) and subsequent colorimetric estimation . Anal. Chem. , 28 : 1816 – 1819 .
  • Wood , A. W. , Goode , R. L. , Chang , R. L. , Levin , W. , Conney , A. H. , Yagi , H. , Dansette , P. M. and Jerina , D. M. 1975 . Mutagenic and cytotoxic activity of benzo(a)pyrene 4,5,7,8‐ and 9,10‐oxides and six corresponding phenols . Proc. Natl. Acad. Sci. U.S.A. , 72 : 3176 – 3180 .
  • Yang , S. K. , Gelboin , H. W. , Trump , B. F. , Autrup , H. and Harris , C. C. 1977 . Metabolic activation of benzo(a)pyrene and binding to DNA in cultured human bronchus . Cancer Res. , 37 : 1210 – 1215 .

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