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Original Articles

Effects of pretreatment with skf‐525a, n‐methyl‐2‐thioimidazole, sodium phenobarbital, or 3‐methylcholanthrene on ethylenethiourea‐induced teratogenicity in hamsters

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Pages 287-300 | Received 10 Jun 1982, Accepted 20 Aug 1982, Published online: 20 Oct 2009

References

  • Anders , M. W. 1971 . Enhancement and inhibition of drug metabolism . Ann. Rev. Pharmacol. , 11 : 37 – 56 .
  • Brattsten , L. B. 1979 . Ecological significance of mixed‐function oxidations . Drug. Metab Rev. , 10 : 35 – 58 .
  • Brodie , B. B. 1956 . Pathways of drug metabolism . J. Pharmacol. , 8 : 1 – 17 .
  • Brody , M. J. , Lukensmeyer , W. A. and Williamson , H. E. 1964 . Inhibition of autoregulation of renal blood flow by SKF 525‐A and fluoroacetate . Proc. Soc. Exp. Biol. Med. , 117 : 79 – 83 .
  • Conney , A. H. , Davison , C. , Gastel , R. and Burns , J. J. 1960 . Adaptive increases in drug metabolizing enzymes induced by phenobarbital and other drugs . J. Pharmacol. Exp. Ther. , 130 : 1 – 8 .
  • Davies , O. L. 1954 . The Design and Analysis of Industrial Experiments , 26 – 27 . London and Edinburgh : Oliver and Boyd .
  • Fantel , A. G. , Greenaway , J. C. , Juchau , M. R. and Shepard , T. H. 1979 . Teratogenic bioactivation of cyclophosphamide in vitro . Life Sci. , 25 : 67 – 72 .
  • Gibson , J. E. and Becker , B. A. 1968 . Effect of phenobarbital and SKF‐525A on the teratogenicity of cyclophosphamide in mice . Teratology , 1 : 393 – 398 .
  • Gibson , J. E. and Becker , B. A. 1971 . Effect of phenobarbital and SKF‐525A on placental transfer of cyclophosphamide in mice . J. Pharmacol. Exp. Ther. , 177 : 256 – 262 .
  • Hakim , R. and Fujimoto , J. M. 1971 . Inhibition of renal tubular transport of morphine by β‐diethylaminoethyl diphenylpropylacetate in the chicken . Biochem. Pharmacol. , 20 : 2647 – 2662 .
  • Hald , H. 1952 . Statistical Theory with Engineering Applications , 388 – 411 . New York : Wiley .
  • Harbison , R. D. and Becker , B. A. 1970 . Effect of phenobarbital and SKF‐525A pretreatment on diphenylhydantoin teratogenicity in mice . J. Pharmacol. Exp. Ther. , 175 : 283 – 288 .
  • Harbison , R. D. and Becker , B. A. 1971 . Effects of phenobarbital or SKF‐525A pretreatment on diphenylhydantoin disposition in pregnant mice . Toxicol. Appl. Pharmacol. , 20 : 573 – 581 .
  • Harbison , R. D. , Mantilla‐Plata , B. and Lubin , D. J. 1977 . Alteration of ?9‐tetrahydrocannabinol‐induced teratogenicity by stimulation and inhibition of its metabolism . J. Pharmacol. Exp. Therap. , 202 : 455 – 465 .
  • Hunter , A. L. and Nal , R. A. 1975 . Inhibition of hepatic mixed‐function oxidase activity in vitro and in vivo by various thiono‐sulfur‐containing compounds . Biochem. Pharmacol. , 24 : 2199 – 2205 .
  • Khera , K. S. 1973 . Ethylenethiourea: Teratogenicity study in rats and rabbits . Teratology , 7 : 243 – 252 .
  • Khera , K. S. and Iverson , F. 1981 . Effects of pretreatment with SKF‐525A, N‐methyl‐2‐thioimidazole, sodium phenobarbital, or methylcholanthrene on ethylenethiourea‐induced teratogenicity in rats . Teratology , 24 : 131 – 137 .
  • Khera , K. S. and Tryphonas , L. 1977 . Ethylenethiourea‐induced hydrocephalus: Pre‐ and postnatal pathogenesis in offspring of rats given a single oral dose during pregnancy . Toxicol. Appl. Pharmacol. , 42 : 85 – 97 .
  • Magus , R. D. , Ricker , D. E. and Fouts , J. R. 1968 . Activation of hydrocortisone‐induced tryptophan pyrrolase of rat liver by SKF 525‐A . Biochem. Pharmacol. , 17 : 2071 – 2080 .
  • Posner , H. S. , Graves , A. , King , C. T. G. and Wilk , A. 1967 . Experimental alteration of the metabolism of chlorocyclizine and the incidence of cleft palate in rats . J. Pharmacol. Exp. Ther. , 155 : 494 – 505 .
  • Poulsen , L. L. , Hyslop , R. M. and Ziegler , D. M. 1974 . S‐Oxidation of thioureylenes catalysed by a microsomal flavoprotein mixed‐function oxidase . Biochem. Pharmacol. , 23 : 3431 – 3440 .
  • Preache , M. M. and Gibson , J. E. 1975 . Effect of food deprivation, phenobarbital and SKF‐525A on teratogenicity induced by 2‐sec‐butyl‐4, 6‐dinitrophenol (Dinoseb) and on disposition of [14C]dinoseb in mice . J. Toxicol. Environ. Health , 1 : 207 – 118 .
  • Teramoto , S. , Shingu , A. , Kaneda , M. and Saito , R. 1978 . Teratogenicity studies with ethylenethiourea in rats, mice and hamsters . Congenital Anomalies (Senten Ijo) , 18 : 11 – 17 .

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