Cardiotoxicity of tricyclic antidepressants in primary cultures of rat myocardial cells

References

• Abernathy , C. O. , Lukacs , L. and Zimmerman , H. J. 1975 . Toxicity of tricyclic antidepressants to isolated rat hepatocytes . Biochem. Pharmacol. , 24 : 347 – 350 .
   PubMed Web of Science ®Google Scholar
• Acosta , D. and Chappell , R. 1977 . Cardiotoxicity of diazepam in cultured heart cells . Toxicology , 8 : 311 – 317 .
   PubMed Web of Science ®Google Scholar
• Acosta , D. , Puckett , M. and McMillin , R. 1978 . Ischemic myocardial injury in cultured heart cells: Leakage of cytoplasmic enzymes from injured cells . In Vitro , 14 : 728 – 732 .
   PubMedGoogle Scholar
• Bianchetti , G. , Bonaccorsi , A. , Chiodaroli , A. , Franco , R. , Garattini , S. , Gomeni , R. and Morselli , P. L. 1977 . Plasma concentrations and cardiotoxic effects of desipramine and protriptyline in the rat . Br. J. Pharmacol. , 60 : 11 – 19 .
   PubMed Web of Science ®Google Scholar
• Dingell , J. V. , Sulser , F. and Gillette , J. R. 1964 . Species differences in the metabolism of imipramine and desmethylimipramine (DMI) . J. Pharmacol. Exp. Ther. , 143 : 14 – 22 .
   PubMed Web of Science ®Google Scholar
• Dumovic , P. , Burrows , G. D. , Vohra , J. , Davies , B. and Scoggins , B. A. 1976 . The effect of tricyclic antidepressant drugs on the heart . Arch. Toxicol. , 32 : 255 – 262 .
   Google Scholar
• Elonen , E. 1974 . Correlation of the cardiotoxicity of tricyclic antidepressants to their membrane effects . Med. Biol. , 52 : 415 – 423 .
   PubMedGoogle Scholar
• Gram , L. F. 1978 . Plasma level monitoring of tricyclic antidepressants: Methodological and pharmacokinetic considerations . Commun. Psychopharmacol. , 2 : 373 – 380 .
   PubMedGoogle Scholar
• Lechat , P. , Auclair , M. C. and Adolphe , M. 1974 . Effect of imipramine on cultured rat heart cells . Toxicol. Appl. Pharmacol. , 27 : 336 – 341 .
   PubMed Web of Science ®Google Scholar
• Lowry , O. H. , Rosebrough , N. J. , Farr , A. L. and Randall , R. J. 1951 . Protein measurements with the folin phenol reagent . J. Biol. Chem. , 193 : 265 – 275 .
   PubMed Web of Science ®Google Scholar
• Mattila , M. J. and Saarnivara , L. 1970 . Amitriptyline toxicity . Lancet , 2 : 1138
   PubMed Web of Science ®Google Scholar
• Mitchell , D. B. and Acosta , D. 1981 . Evaluation of the cytotoxicity of tricyclic antidepressants in primary cultures of rat hepatocytes . J. Toxicol. Environ. Health , 7 : 83 – 92 .
   PubMed Web of Science ®Google Scholar
• Mitchell , D. , Santone , K. and Acosta , D. 1980 . Evaluation of cytotoxicity in cultured cells by enzyme leakage . J. Tissue Culture Meth. , 6 : 113 – 116 .
   Google Scholar
• Robinson , D. S. , Cooper , T. B. , Ravarls , C. L. , Ives , J. O. , Niles , A. , Barlett , D. and Lamburn , K. R. 1979 . Plasma tricyclic drug levels in amitriptyline‐treated depressed patients . Psychopharmacology , 63 : 223 – 231 .
   PubMed Web of Science ®Google Scholar
• Spiker , D.G. , Weiss , A. N. , Chang , S. S. , Ruwitch , J. F. and Biggs , J. T. 1975 . Tricyclic antidepressant overdose: Clinical presentations and plasma levels . Clin. Pharmacol. Ther. , 18 : 539 – 546 .
   PubMed Web of Science ®Google Scholar
• Tolnai , S. 1975 . “ A method for viable cell count ” . In Tissue Culture Association Manual , Edited by: Evans , V. J. , Perry , V. P. and Vincents , M. M. vol. 1 , 37 – 38 . Rockville, Md. : Tissue Culture Assoc. .
   Google Scholar
• Wenzel , D. G. , Wheatley , J. W. and Byrd , G. D. 1970 . Effects of nicotine on cultured heart cells . Toxicol. Appl. Pharmacol. , 17 : 774 – 785 .
   PubMed Web of Science ®Google Scholar
• Ziegler , V. E. , Co , B. T. , Taylor , J. R. , Clayton , P. J. and Biggs , J. T. 1976a . Amitrityline plasma levels and therapeutic response . Clin. Pharmacol. Ther. , 19 : 795 – 801 .
   PubMed Web of Science ®Google Scholar
• Ziegler , V. E. , Taylor , J. R. , Co , B. T. and Biggs , J. T. 1976b . Nortriptyline plasma levels and therapeutic response . Clin. Pharmacol. Ther. , 20 : 458 – 463 .
   PubMed Web of Science ®Google Scholar