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Original Articles

Changes in early alveolar particle clearance due to single and repeated nitrogen dioxide exposures in the rabbit

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Pages 255-266 | Received 20 Feb 1986, Accepted 30 Apr 1986, Published online: 20 Oct 2009

References

  • Acton , J. D. and Myrvik , Q. N. 1972 . Nitrogen dioxide effects on alveolar macrophages . Arch. Environ. Health , 24 : 48 – 52 .
  • Bils , R. F. and Christie , B. R. 1980 . The experimental pathology of oxidant and air pollution inhalation . Int. Rev. Exp. Pathol. , 21 : 195 – 293 .
  • Creasia , D. A. 1980 . “ Pathogenesis of oxidant‐induced respiratory disease in reference to respiratory clearance of radiolabeled particles ” . In Pulmonary Toxicology of Respiratory Particles , Edited by: Saunders , C. L. , Cross , F. T. , Dagle , C. E. and Mahaffey , J. A. 134 – 148 . Springfield, Va. : National Technical Information Service . Conf.‐791002.
  • Creasia , D. A. 1981 . Pathogenesis of nitrogen dioxide‐induced respiratory lesions in reference to respiratory clearance of inhaled participates . J. Toxicol. Environ. Health , 8 : 857 – 887 .
  • Dawson , S. V. and Schenker , M. B. 1979 . Health effects of inhalation of ambient concentrations of nitrogen dioxide . Am. Rev. Respir. Dis. , 120 : 281 – 292 .
  • Dowell , A. E. , Kilburn , K. H. and Pratt , P. C. 1971 . Short‐term exposure to nitrogen dioxide: Effects on pulmonary ultrastructure, compliance, and the surfactant system . Arch. Intern. Med. , 128 : 74 – 80 .
  • Driscoll , K. E. , Vollmuth , T. A. and Schlesinger , R. B. 1986 . Early alveolar clearance of particles in rabbits undergoing acute and subchronic inhalation exposure to O3 . Fundam. Appl. Toxicol. , in press
  • Ellis , E. C. 1975 . Technical assistance document for the chemiluminescence measurement of nitrogen dioxide , Research Triangle Park, N.C. : Environmental Protection Agency . EPA‐600/4–75–003
  • Environmental Protection Agency . 1982 . Air quality criteria for oxides of nitrogen , Research Triangle Park, N.C. : Environmental Protection Agency . EPA‐600/8–82–026
  • Evans , M.J. , Cabral , L. J. , Stephens , R. J. and Freeman , C. 1973 . Cell division of alveolar macrophages in rat lung following exposure to NO2 . Am. J. Pathol. , 70 : 199 – 208 .
  • Fairchild , E. J. 1967 . Tolerance mechanisms . Arch. Environ. Health , 14 : 111 – 126 .
  • Ferin , J. and Leach , L. J. 1973 . The effect of SO2 on lung clearance of TiO2 particles in rats . Am. Ind. Hyg. Assoc. J. , 34 : 260 – 263 .
  • Ferin , J. and Leach , L. J. 1977 . “ The effects of selected air pollutants on clearance of titanic oxide particles from the lungs of rats ” . In Inhaled Particles IV , Edited by: Walton , W. H. 333 – 341 . Oxford : Pergamon . pt. 1
  • Fisher , M. V. , Morrow , P. E. and Yuile , C. L. 1973 . Effect of Freund's complete adjuvant upon clearance of iron‐59 oxide from rat lungs . J. Reticuloendothel. Soc. , 13 : 536 – 556 .
  • Gardner , D. E. 1984 . Oxidant‐induced enhanced sensitivity to infection in animal models and their extrapolations to man . J. Toxicol. Environ. Health , 13 : 423 – 439 .
  • Glaser , V. , Hochrainer , H. , Kloppel , H. and Kuhnen , H. 1985 . Low level chromium (VI) inhalation effects on alveolar macrophages and immune functions in Wistar rats . Arch. Toxicol. , 57 : 250 – 256 .
  • Graham , J. A. and Miller , F. J. 1985 . “ Interference with lung defenses by nitrogen dioxide exposure ” . In Indoor Air and Human Health , Edited by: Gammage , R. B. and Kaye , S. V. 279 – 296 . Chelsea, Mich. : Lewis .
  • Guidotti , T. L. 1978 . The higher oxides of nitrogen: Inhalation toxicology . Environ. Res. , 15 : 443 – 472 .
  • Hackett , N. A. 1979 . Proliferation of lung and airway cells induced by nitrogen dioxide . J. Toxicol. Environ. Health , 5 : 917 – 928 .
  • Hatch , T. and Gross , P. 1964 . Pulmonary Deposition and Retention of Inhaled Aerosols , New York : Academic .
  • Jones , J. G. 1984 . “ Clearance of inhaled particles from the alveoli ” . In Aerosols and the Lung , Edited by: Clarke , S. and Pavia , D. 170 – 196 . Boston : Butterworths .
  • Katsnelson , B. A. and Privalova , L. I. 1984 . Recruitment of phagocytizing cells into the respiratory tract as a response to the cytotoxic action of deposited particles . Environ. Health Perspect. , 55 : 313 – 325 .
  • Kenoyer , J. L. , Phalen , R. F. and Davis , J. R. 1981 . Particle clearance from the respiratory tract as a test of toxicity: Effect of ozone on short and long term clearance . Exp. Lung Res. , 2 : 111 – 120 .
  • Kilburn , K. H. 1984 . Particles causing lung disease . Environ. Health Perspect. , 55 : 97 – 109 .
  • LaBelle , R. and Brieger , H. 1960 . The fate of inhaled particles in the early postexposure period. II. The role of pulmonary phagocytosis . Arch. Environ. Health , 5 : 423 – 427 .
  • Lehnert , B. E. and Morrow , P. E. 1985 . Association of 59iron oxide with alveolar macrophages during alveolar clearance . Exp. Lung. Res. , 9 : 1 – 16 .
  • Morrow , P. E. 1973 . Alveolar clearance of aerosols . Arch. Intern. Med. , 131 : 101 – 108 .
  • Morrow , P. E. 1984 . Toxicological data on NOx: An overview . J. Toxicol. Environ. Health , 13 : 205 – 227 .
  • Naumann , B. D. and Schlesinger , R. B. 1986 . Assessment of early alveolar clearance and macro‐phage function following an acute oral inhalation of sulfuric acid mist . Exp. Lung Res. , 11 : 13 – 33 .
  • Newton , P. , Latendresse , J. II , Mattie , D. and Pfledderer , C. 1985 . Alterations in alveolar clearance after 4‐ipomeanol‐induced necrosis of Clara and ciliated cells in the terminal bronchiole of the rat . Toxicol. Appl. Pharmacol. , 80 : 534 – 541 .
  • Phalen , R. F. , Kenoyer , J. L. , Crocker , T. T. and McClure , T. R. 1980 . Effects of sulfate aerosols in combination with ozone on elimination of tracer particles inhaled by rats . J. Toxicol. Environ. Health , 6 : 797 – 810 .
  • Schlesinger , R. B. 1985 . Clearance from the respiratory tract . Fundam. Appl. Toxicol. , 5 : 435 – 450 .
  • Schlesinger , R. B. , Vollmuth , T. A. , Naumann , B. D. and Driscoll , K. E. 1986a . Measurement of particle clearance from the alveolar region of the rabbit respiratory tract . Fundam. Appl. Toxicol. , in press
  • Schlesinger , R. B. , Driscoll , K. E. , Naumann , B. D. and Vollmuth , T. A. 1986b . Particle clearance from the lungs: Assessment of effects due to inhaled irritants . Ann. Occup. Hyg. , in press
  • Sexton , K. , Letz , R. and Spengler , J. D. 1983 . Estimating human exposure to nitrogen dioxide: An indoor/outdoor modeling approach . Environ. Res. , 32 : 151 – 166 .
  • Sherwin , R. P. and Carlson , D. A. 1973 . Protein content of lung lavage fluid of guinea pigs exposed to 0.4 ppm nitrogen dioxide . Arch. Environ. Health , 47 : 90 – 93 .
  • Sone , S. , Brennan , L. M. and Creasia , D. A. 1983 . In vivo and in vitro NO2 exposures enhance phagocytic and tumoricidal activities of rat alveolar macrophages . J. Toxicol. Environ. Health , 11 : 151 – 163 .
  • Sorokin , S. P. and Brain , J. D. 1975 . Pathways of clearance in mouse lungs exposed to iron oxide aerosols . Anat. Rec. , 181 : 581 – 626 .
  • Spengler , J. D. and Cohen , M. A. 1985 . “ Emissions from indoor combustion sources ” . In Indoor Air and Human Health , Edited by: Gammage , R. B. and Kaye , S. V. 261 – 270 . Chelsea, Mich. : Lewis .
  • Stephens , R. J. , Freeman , C. and Evans , M. J. 1972 . Early response of lungs to low levels of nitrogen dioxide . Arch. Environ. Health , 24 : 160 – 179 .
  • Vassallo , C. L. , Domm , B. M. , Poe , R. H. , Duncombe , M. L. and Gee , J. B. L. 1973 . NO2 gas and NO2‐ effects on alveolar macrophage phagocytosis and metabolism . Arch. Environ. Health , 26 : 270 – 274 .
  • Wright , E. S. , Vang , M. J. , Finkelstein , J. N. and Mavis , R. D. 1982 . Changes in phospholipid biosynthetic enzymes in type II cells and alveolar macrophages isolated from rat lungs after NO2 exposure . Toxicol. Appl. Pharmacol. , 66 : 305 – 311 .
  • Zar , J. H. 1984 . Biostatistical Analysis., , 2d ed. , Englewood Cliffs, N.J. : Prentice‐Hall .

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