Teratogenicity of 5‐azacytidine in the Sprague‐Dawley rat

References

• Beyer , P. E. and Chernoff , N. 1986 . The induction of supernumerary ribs in rodents: Role of the maternal stress . Teratogen. Carcinogen. Mutagen , 6 : 419 – 429 .
   PubMedGoogle Scholar
• Butler , H. and Juurlink , B. H. J. 1987 . An Atlas for Staging Mammalian and Chick Embryos , 89 – 101 . Boca Raton, Fla. : CRC Press .
   Google Scholar
• Compere , S. J. and Palmiter , R. D. 1981 . DNA methylation controls the inducibility of the mouse metallothionein‐l gene in lymphoid cells . Cell , 25 : 233 – 240 .
   PubMed Web of Science ®Google Scholar
• Constantinides , P. C. , Taylor , S. M. and Jones , P. A. 1978 . Phenotypic conversion of cultured mouse embryo cells by aza pyrimidine nucleosides . Develop. Biol , 66 : 57 – 71 .
   PubMed Web of Science ®Google Scholar
• Felsenfeld , C. and McGhee , J. 1982 . Methylation and gene control . Nature , 296 : 602 – 603 .
   PubMed Web of Science ®Google Scholar
• Harrison , J. J. , Aniscowicz , A. , Gadi , I. K. , Raffeid , M. and Sager , R. 1983 . Azacytidine‐induced tumorigenesis of CHEF/18 cells: Correlated DNA methylation and chromosome changes . Proc. Natl. Acad. Sci. USA , 80 : 6606 – 6610 .
   PubMedGoogle Scholar
• Haseman , J. K. and Hogan , M. D. 1975 . Selection of the experimental unit in teratology studies . Teratology , 12 : 165 – 172 .
   PubMedGoogle Scholar
• Jones , P. A. and Taylor , S. M. 1980 . Cellular differentiation, cytidine analogs and DNA methylation . Cell , 20 : 85 – 93 .
   PubMed Web of Science ®Google Scholar
• Kurishita , A. 1989 . Histological study of cell death in digital malformations induced by 5‐azacytidine: Suppressive effect of caffeine . Teratology , 39 : 163 – 172 .
   PubMedGoogle Scholar
• Kurishita , A. and Ihara , T. 1987 . Inhibitory effect of caffeine on 5‐azacytidine‐induced digital malformations in the rat . Teratology , 35 : 247 – 252 .
   Google Scholar
• Langman , J. and Shimada , M. 1971 . Cerebral cortex of the mouse after prenatal chemical insult . Am. J. Anat. , 132 : 355 – 374 .
   Google Scholar
• Li , L. H. , Olin , E. J. , Fraser , T. J. and Bhuyan , B. K. 1970 . Phase specificity of 5‐azacytidine against mammalian cells in tissue culture . Cancer Res. , 30 : 2770 – 2775 .
   PubMed Web of Science ®Google Scholar
• Li , L. H. , Buskirk , H. H. , Blowers , C. L. , Neil , G. L. and Hanka , L. J. 1984 . Biological evaluation of stability of 5‐azacytidine . J. Antibiotics , 37 : 419 – 421 .
   Google Scholar
• Michalowsky , L. A. and Jones , P. A. 1989 . DNA methylation and differentiation . Environ. Health Perspect. , 80 : 189 – 197 .
   Google Scholar
• Riggs , A. D. and Jones , P. A. 1983 . 5‐Methylcytosine, gene regulation, and cancer . Adv. Cancer Res. , 40 : 1 – 30 .
   PubMed Web of Science ®Google Scholar
• Santi , D. V. , Carrett , C. E. and Barr , P. J. 1983 . On the mechanism of DNA‐cytosine methyltransferases by cytosine analogs . Cell , 33 : 9 – 10 .
   PubMed Web of Science ®Google Scholar
• Schmahl , W. , Torok , P. and Kriegel , H. 1984 . Embryotoxicity of 5‐azacytidine: Phase‐ and dose‐specificity studies . Arch. Toxicol. , 55 : 143 – 147 .
   Google Scholar
• Seifertova , M. , Vesely , J. and Sorm , F. 1968 . Effect of 5‐azacytidine on developing mouse embryo . Experientia , 24 : 487 – 488 .
   Google Scholar
• Svata , M. , Raska , K. Jr. and Sorm , F. 1966 . Interruption of pregnancy by 5‐azacytidine . Experientia , 22 : 53
   Google Scholar
• Takeuchi , I. K. and Murakami , U. 1978 . The preventive influence of cysteamine on the teratogenic action of 5‐azacytidine . Life Sci. , 23 : 897 – 900 .
   PubMed Web of Science ®Google Scholar
• Takeuchi , I. K. and Takeuchi , Y. K. 1978 . Cell death induced by 5‐azacytidine in the telencephalic wall of the rat fetus . Annot. Zoo!. Jpn. , 51 : 10 – 19 .
   Google Scholar
• Takeuchi , I. K. and Takeuchi , Y. K. 1985 . 5‐Azacytidine‐induced exencephaly in mice . J. Anat. , 140 : 403 – 412 .
   PubMed Web of Science ®Google Scholar
• Taylor , S. M. and Jones , P. A. 1979 . Multiple new phenotypes induced in 10T1/2 and 3T3 cells treated with 5‐azacytidine . Cell , 17 : 771 – 779 .
   PubMed Web of Science ®Google Scholar
• Taylor , S. M. and Jones , P. A. 1982 . Changes in phenotypic expression in embryonic and adult cells treated with 5‐azacytidine . J. Cell. Physiol. , 111 : 187 – 194 .
   PubMedGoogle Scholar