Pulmonary arachidonic acid metabolism following acute exposures to ozone and nitrogen dioxide

References

• Bakhle , Y. S. and Ferreira , S. H. 1985 . “ Lung metabolism of eicosanoids: Prostaglandins, prostacyclin, thromboxane, and leuktrienes ” . In Handbook of Physiology, Section 3: The Respiratory System vol. 1 Circulation and Nonrespiratory Functions , Edited by: Fishman , A. P. and Fisher , A. R. vol. 1 , 365 – 386 . Bethesda, Md. : American Physiological Society .
   Google Scholar
• Chang , L.‐Y. , Mercer , R. R. , Stockstill , B. L. , Miller , F. J. , Graham , J. A. , Ospital , J.J. and Crapo , J. D. 1988 . Effects of low levels of NO2 on terminal bronchiolar cells and its relative toxicity compared to O3 . Toxicol. Appl. Pharmacol. , 96 : 451 – 464 .
   PubMedGoogle Scholar
• Chaudhari , A. , Sivarajah , K. , Warnock , R. , Eling , T. E. and Anderson , M. W. 1979 . Inhibition of pulmonary prostaglandin metabolism by exposure of animals to oxygen or nitrogen dioxide . Biochem. J. , 184 : 51 – 57 .
   PubMed Web of Science ®Google Scholar
• Coffin , K. E. , Gardner , D. E. , Holzman , R. S. and Wolock , F. J. 1968 . Influence of ozone on pulmonary cells . Arch. Environ. Health , 16 : 633 – 636 .
   PubMed Web of Science ®Google Scholar
• Diggle , W. M. and Gage , J. C. 1955 . The toxicity of ozone in the presence of oxides of nitrogen . Br. J. Ind. Med. , 12 : 60 – 64 .
   PubMedGoogle Scholar
• Driscoll , K. E. , Leikauf , G. D. and Schlesinger , R. B. 1988 . Effects of in vitro and in vivo ozone exposure on eicosanoid production by rabbit alveolar macrophages . Inhal. Toxicol. , : 109 – 122 . Premier lssue
   Google Scholar
• Ehrlich , R. 1980 . Interaction between environmental pollutants and respiratory infections . Environ. Health Perspect. , 35 : 89 – 100 .
   PubMed Web of Science ®Google Scholar
• Ehrlich , R. , Findlay , J. C. , Fenters , J. D. and Gardner , D. E. 1977 . Health effects of short‐term inhalation of nitrogen dioxide and ozone mixtures . Environ. Res. , 14 : 223 – 231 .
   PubMed Web of Science ®Google Scholar
• Eling , T. E. , Henke , D. and Danilowicz , R. 1988 . Arachidonic acid metabolism in respiratory epithelial cells . Gen. Pharmacol. , 19 : 313 – 316 .
   PubMedGoogle Scholar
• Folinsbee , L. J. , Bedi , J. F. and Horvath , S. M. 1981 . Combined effects of ozone and nitrogen dioxide on respiratory function in man . Am. Ind. Hyg. Assoc. J. , 42 : 534 – 541 .
   PubMed Web of Science ®Google Scholar
• Freeman , G. , Juhos , L. T. , Furiosi , N. J. , Mussenden , R. , Stephens , R. T. and Evans , M. J. 1974 . Pathology of pulmonary disease from exposure to interdependent ambient gases (nitrogen dioxide and ozone) . Arch. Environ. Health , 29 : 203 – 210 .
   PubMed Web of Science ®Google Scholar
• Giri , S. N. , Hollinger , M. A. and Schiedt , M. J. 1980 . The effects of ozone and paraquat on PGF2α and PGE2 in plasma and combined pleural effusion and lung lavage of rats . Environ. Res. , 21 : 467 – 476 .
   PubMed Web of Science ®Google Scholar
• Goldstein , E. , Warshauer , D. , Lippert , W. and Tarkington , B. 1974 . Ozone and nitrogen dioxide exposure: Murine pulmonary defense mechanisms . Arch. Environ. Health , 28 : 85 – 90 .
   PubMed Web of Science ®Google Scholar
• Gryglewski , R. J. 1987 . Metabolites of arachidonic acid in the lung . Agents Actions , 21 (suppl.) : 179 – 193 .
   PubMedGoogle Scholar
• Guidotti , T. L. 1978 . The higher oxides of nitrogen: Inhalation toxicology . Environ. Res. , 15 : 443 – 472 .
   PubMed Web of Science ®Google Scholar
• Gunnison , A. F. , Finkelstein , I. , Weideman , P. , Su , W.‐Y. , Sobo , M. and Schlesinger , R. B. 1990 . Effect of age on ozone‐induced pulmonary eicosanoid metabolism . Toxicologist , 9 : 100
   Google Scholar
• Hackney , J. D. , Linn , W. S. , Law , D. C. , Karuza , S. K. , Greenberg , H. , Buckley , R. D. and Pederson , E. E. 1975a . Experimental studies on human health effects of air pollutants. III. Two‐hour exposure to ozone alone and in combination with other pollutant gases . Arch. Environ. Health , 30 : 385 – 390 .
   PubMed Web of Science ®Google Scholar
• Hackney , J. D. , Linn , W. S. , Mohler , J. G. , Pederson , E. E. , Breisacher , P. and Russo , A. 1975b . Experimental studies on human health effects of air pollutants. II. Four‐hour exposure to ozone alone and in combination with other pollutant gases . Arch. Environ. Health , 30 : 379 – 384 .
   PubMed Web of Science ®Google Scholar
• Henderson , R. F. , Rebar , A. H. , DeNicola , D. B. and Henderson , T. R. 1980 . “ The use of pulmonary lavage fluid in screening for early indicators of lung injury ” . In Pulmonary Toxicology of Respirable Particles , Edited by: Sanders , C. L. , Cross , F. T. , Dagle , G. E. and Mahaffey , J. A. 378 – 390 . Washington, DC : U.S. Department of Energy .
   Google Scholar
• Henderson , R. F. , Leung , H. W. , Harmsen , A. G. and McClellan , R. O. 1988 . Species differences in release of arachidonate metabolites in response to inhaled diluted diesel exhaust . Toxicol Lett. , 42 : 325 – 333 .
   PubMedGoogle Scholar
• Keller , M. D. , Lanese , R. R. , Mitchell , R. I. and Cote , R. W. 1979 . Respiratory illness in households using gas or electricity for cooking . Environ Res. , 19 : 495 – 515 .
   PubMed Web of Science ®Google Scholar
• Klein , L. S. , Fisher , A. B. , Soltoff , S. and Coburn , R. F. 1978 . Effect of O2 exposure on pulmonary metabolism of prostaglandin E2 . Am. Rev. Respir. Dis. , 118 : 622 – 625 .
   PubMed Web of Science ®Google Scholar
• Kobayashi , T. 1986 . Effects of nitrogen dioxide exposure on the contents of prostaglandins and thromboxane B2 in broncho alveolar lavage . Prostaglandins , 31 : 469 – 475 .
   PubMed Web of Science ®Google Scholar
• Kobayashi , T. , Morita , I. and Murota , S‐L. 1983 . Effects of nitrogen dioxide exposure on prostacyclin synthesis in lung and thromboxane A2 synthesis in platelets in rats . Prostaglandins , 26 : 303 – 310 .
   PubMedGoogle Scholar
• Lee , J.‐S. , Afifi , A. A. and Mustafa , M. G. 1989 . Effects of short‐term, single and combined exposure of rats to NO2 and O3 on lung tissue enzyme activities . Inhal. Toxicol. , 1 : 21 – 35 .
   Google Scholar
• Leikauf , G. D. , Driscoll , K. D. and Wey , H. E. 1988 . Ozone‐induced augmentation of eicosanoid metabolism in epithelial cells from bovine trachea . Am. Rev. Respir. Dis. , 137 : 435 – 442 .
   PubMed Web of Science ®Google Scholar
• Mehlman , M. A. and Borek , C. 1987 . Toxicity and biochemical mechanisms of ozone . Environ. Res. , 42 : 36 – 53 .
   PubMed Web of Science ®Google Scholar
• Menzel , D. B. 1984 . Ozone: An overview of its toxicity in man and animals . J Toxicol. Environ. Health , 13 : 183 – 204 .
   PubMed Web of Science ®Google Scholar
• Miller , P. D. , Ainsworth , D. , Lam , H. F. and Amdur , M. O. 1987 . Effect of ozone exposure on lung functions and plasma prostaglandin and thromboxane concentrations in guinea pig . Toxicol. Appl. Pharmacol. , 88 : 132 – 140 .
   PubMed Web of Science ®Google Scholar
• Morrow , P. E. 1984 . Toxicological data on NOX: An overview . J Toxicol. Environ. Health , 13 : 205 – 227 .
   PubMed Web of Science ®Google Scholar
• Mustafa , M. G. and Tierney , D. F. 1978 . Biochemical and metabolic changes in lung with oxygen, ozone, and nitrogen dioxide toxicity . Am. Rev. Respir. Dis. , 118 : 1061 – 1090 .
   PubMed Web of Science ®Google Scholar
• Mustafa , M. G. , Faeder , E. J. and Lee , S. D. 1980 . “ Biochemical effect of nitrogen dioxide on animal lungs ” . In Nitrogen Oxides and Their Effects of Health , Edited by: Lee , S. D. 161 – 179 . Ann Arbor, Mich. : Ann Arbor Science .
   Google Scholar
• Mustafa , M. G. , Elsayed , N. M. and Lee , S. D. 1985 . “ The combined effects of ozone and nitrogen dioxide on pulmonary biochemistry ” . In Evaluation of the Scientific Basis for Ozone/Oxidants Standards , Edited by: Lee , S. D. 337 – 347 . Pittsburgh, Pa. : Air Pollution Control Association .
   Google Scholar
• Mustafa , M. G. , Elsayed , N. M. , von Dohlen , F. M. , Hassett , C. M. , Postlethwait , E. M. , Quinn , C. L. , Graham , J. A. and Gardner , D. E. 1984 . A comparison of biochemical effects of nitrogen dioxide, ozone, and their combination in mouse lung. I. Intermittent exposures . Toxicol. Appl. Pharmacol. , 72 : 82 – 90 .
   PubMed Web of Science ®Google Scholar
• National Research Council . 1989 . Biologic Markers in Pulmonary Toxicology , Washington, D.C. : National Academy Press .
   Google Scholar
• Nowak , J. 1984 . Eicosanoids and the lungs . Ann. Clin. Res. , 16 : 269 – 286 .
   PubMedGoogle Scholar
• Pryor , W. A. , Dooley , M. M. and Church , D. F. 1983 . “ Mechanisms for the reaction of ozone with biological molecules, the source of the toxic effects of ozone ” . In The Biomedical Effects of Ozone and Related Photochemical Oxidants , Edited by: Lee , S. D. , Mustafa , M. G. and Mehlman , M. A. 7 – 19 . Princeton, N.J. : Princeton Scientific Publishers .
   Google Scholar
• Rabinowitz , J. L. and Bassett , D. J. P. 1988 . Effect of 2 ppm ozone exposure on rat lung lipid fatty acids . Exp. Lung Res. , 14 : 477 – 489 .
   PubMed Web of Science ®Google Scholar
• Reitjens , I. M. C. M. , Poelen , M. C. M. , Hempenius , R. A. , Gijbels , M. J. and Alink , G. M. 1986 . Toxicity of ozone and nitrogen dioxide to alveolar macrophages: Comparative study revealing differences in their mechanisms of toxic action . J. Toxicol. Environ. Health , 19 : 555 – 568 .
   PubMedGoogle Scholar
• Salmon , J. A. and Higgs , G. A. 1987 . Prostaglandins and leukotrienes as inflammatory mediators . B. Med. Bull. , 43 : 285 – 296 .
   PubMed Web of Science ®Google Scholar
• Schelegle , E. S. , Adams , W. C. , Giri , S. N. and Siefkin , A. D. 1989 . Acute ozone exposure increases plasma prostaglandin F2α in ozone‐sensitive human subjects . Am. Rev. Respir. Dis. , 140 : 211 – 216 .
   PubMed Web of Science ®Google Scholar
• Schlesinger , R. B. 1987 . Functional assessment of rabbit alveolar macrophages following intermittent inhalation exposures to sulfuric acid mist . Fundam. Appl. Toxicol. , 8 : 328 – 334 .
   PubMedGoogle Scholar
• Schlesinger , R. B. , Naumann , B. D. and Chen , L. C. 1983 . Physiological and histological alterations in the bronchial mucociliary clearance system of rabbits following intermittent oral or nasal inhalation of sulfuric acid mist . J. Toxicol. Environ. Health , 12 : 441 – 465 .
   PubMed Web of Science ®Google Scholar
• Schlesinger , R. B. , Driscoll , K. E. , Naumann , B. D. and Vollmuth , T. A. 1988 . Particle clearance from the lungs: Assessment of effects due to inhaled irritants . Ann. Occup. Hyg. , 32 (suppl. 1) : 113 – 123 .
   Google Scholar
• Schlesinger , R. B. , Gunnison , A. F. and Zelikoff , J. T. 1990 . Modulation of pulmonary eicosanoid metabolism following exposure to sulfuric acid . Fundam. Appl. Toxicol. , 15 : 151 – 162 .
   PubMedGoogle Scholar
• Seltzer , J. , Bigby , B. G. , Stulberg , M. , Holtzman , M. J. , Nadel , J. A. , Ueki , I. F. , Leikauf , G. D. , Goetzl , E. J. and Boushey , H. A. 1986 . Ozone‐induced change in bronchial reactivity to methacholine and airway inflammation in humans . J. Appl. Physiol. , 60 : 1321 – 1326 .
   PubMed Web of Science ®Google Scholar
• Sexton , K. , Letz , R. and Spengler , J. D. 1983 . Estimating human exposures to nitrogen dioxide: An indoor/outdoor modeling approach . Environ. Res. , 32 : 151 – 166 .
   PubMed Web of Science ®Google Scholar
• Shore , S. A. , Austen , K. F. and Drazen , J. M. 1989 . “ Eicosanoids and the lung ” . In Lung Cell Biology , Edited by: Massaro , D. 1011 – 1089 . New York : Marcel Dekker .
   Google Scholar
• Spengler , J. D. and Cohen , M. A. 1985 . “ Emissions from indoor combustion sources ” . In Indoor Air and Human Health , Edited by: Gammage , R. B. and Kaye , S. V. 261 – 270 . Chelsea, Mich. : Lewis Publishers .
   Google Scholar
• Toyama , T. , Tsunoda , T. , Nakasa , M. , Higashi , T. and Nakadate , T. 1981 . Airway response to short‐term inhalation of NO2 O3 and their mixture in healthy men . Jpn. J. Ind. Health , 23 : 285 – 293 .
   PubMedGoogle Scholar
• U.S. Environmental Protection Agency . 1982 . SAROAD Data File for 1981 , Research Triangle Park, N. C. : Office of Air Quality Planning and Standards .
   Google Scholar
• von Nieding , C. , Wagner , H. M. , Krekeler , H. , Lollgen , H. , Fries , W. and Beuthan , A. 1979 . Controlled studies of human exposure to single and combined action of NO2 O3 and SO2 . Int. Arch. Occup. Environ. Health , 43 : 195 – 210 .
   PubMed Web of Science ®Google Scholar
• Wade , W. A. III , Cote , W. A. and Yocom , J. E. 1975 . A study of indoor air quality . J. Air Pollut. Control Assoc. , 25 : 931 – 939 .
   Google Scholar
• Watanabe , H. , Fakase , O. and Isomura , K. 1980 . “ Combined effects of nitrogen oxides and ozone on mice ” . In Nitrogen Oxides and Their Effects on Health , Edited by: Lee , S. D. 181 – 189 . Ann Arbor, Mich. : Ann Arbor Science .
   Google Scholar
• Yokoyama , E. , Ichikawa , I. and Kawai , K. 1980 . “ Does nitrogen dioxide modify the respiratory effects of ozone? In ” . In Nitrogen Oxides and Their Effects on Health , Edited by: Lee , S. D. 217 – 229 . Ann Arbor, Mich. : Ann Arbor Science .
   Google Scholar
• Zar , J. H. 1984 . Biostatistical Analysis , Englewood Cliffs, N.J. : Prentice‐Hall .
   Google Scholar