Influence of the dose levels of cocarcinogen ferric oxide on the metabolism of benzo[a]pyrene by pulmonary alveolar macrophages in suspension culture

References

• Autrup , H. , Harris , C. , Stoner , G. , Selkirk , J. , Schafer , P. and Trump , B. 1978 . Metabolism of 3H benzo(a)pyrene by cultured human bronchus and cultured human pulmonary alveolar macro‐phages . Lab. Invest. , 38 : 217
   PubMed Web of Science ®Google Scholar
• Autrup , H. C. , Harris , P. , Schafer , P. W. , Trump , B. F. , Stoner , C. D. and Hsu , I. C. 1979 . Uptake of benzo(a)pyrene‐ferric oxide particulates by human pulmonary macrophages and release of benzo(a)pyrene and its metabolites . Proc. Soc. Exp. Biol. Med. , 16 : 280 – 284 .
   Google Scholar
• Axelson , O. and Sjoberg , A. 1979 . Cancer incidence and exposure to iron oxide dust . J. Occup. Med. , 21 : 419 – 422 .
   PubMedGoogle Scholar
• Becci , P. , McDowell , E. M. and Trump , B. F. 1978 . The respiratory epithelium. VI. Histogenesis of lung tumors induced by benzo(a)pyrene‐ferric oxide in the hamster . J. Natl. Cancer Inst. , 61 : 607 – 618 .
   PubMed Web of Science ®Google Scholar
• Bevan , D. R. and Manger , W. E. 1985 . Effect of particulates on metabolism and mutagenicity of benzo(a)pyrene . Chem. Biol. Interact. , 56 : 13 – 28 .
   PubMedGoogle Scholar
• Bond , J. , Butler , M. , Medinsky , M. , Muggenburg , B. and McClellan , R. 1984 . Dog pulmonary mac‐rophage metabolism of free and particle‐associated [14C]benzo(a)pyrene . J. Toxicol. Environ. Health , 14 : 181 – 189 .
   PubMed Web of Science ®Google Scholar
• Castranova , V. , Bowman , L. , Miles , P. and Reasor , M. 1980 . Toxicity of metal ions to alveolar macrophages . Am. J. Ind. Med. , 1 : 349
   PubMedGoogle Scholar
• Centers for Disease Control . 1983 . Leading work related diseases and inquires USA . Morbid. Mortal. Weekly Rep. , 32 : 24 – 26 .
   PubMedGoogle Scholar
• Chrisp , C. E. and Fisher , G. L. 1980 . Mutagenicity of airborne particles . Mutat. Res. , 76 : 143 – 164 .
   PubMedGoogle Scholar
• Falk , H. L. 1970 . “ Chemical definitions of inhalation hazards ” . In Inhalation Carcinogenesis , USAEC Symposium Series 18 Edited by: Hanna , M. G. Jr. , Nettesheim , P. and Gilbert , J. R. 13 – 26 . Oak Ridge, Tenn.
   Google Scholar
• Gelboin , H. 1980 . Benzo(a)pyrene metabolism, activation, and carcinogenesis: Role and regulation of mixed function oxidases and related enzymes . Physiol. Rev. , 60 : 1107 – 1166 .
   PubMed Web of Science ®Google Scholar
• Greife , A. , Schoeny , R. and Warshawsky , D. 1988 . “ Effect of the cocarcinogen ferric oxide on ben‐zo(a)pyrene metabolism by hamster alveolar macrophages ” . In PAHs: Chemical and Biological Effects , Edited by: Cooke , M. and Dennis , A. 317 – 327 . Columbus, Ohio : Battelle Press .
   Google Scholar
• Harris , C. C. , Hsu , I. C. , Stoner , G. D. , Trump , B. F. and Selkirk , J. K. 1978 . Human pulmonary alveolar macrophages metabolize benzo(a)pyrene to proximate and ultimate mutagens . Nature , 272 : 633 – 634 .
   PubMed Web of Science ®Google Scholar
• Henry , M. C. , Port , C. D. and Kaufman , D. G. 1975 . Importance of physical properties of benzo(a)pyrene‐ferric oxide mixtures in lung tumor induction . Cancer Res. , 35 : 207 – 217 .
   PubMed Web of Science ®Google Scholar
• Hsu , I. C. , Harris , C. C. , Yamaguchi , M. , Trump , B. F. and Schafer , P. W. 1979 . Induction of ouabain‐resistant mutation and sister chromatid exchanges in Chinese hamster cells with chemical carcinogens mediated by human pulmonary macrophages . J. Clin. Invest. , 64 : 1245 – 1252 .
   PubMed Web of Science ®Google Scholar
• Hubbard , S. A. , Davis , P. J. B. , Hunt , C. M. and McDonald , R. 1986 . Effects of benzo(a)pyrene‐coated particles in a bacterial mutagenicity test and on macrophages in culture . Food Chem. Toxicol. , 24 : 697 – 698 .
   Google Scholar
• Hughes , T. J. , Pellizzari , E. , Little , L. , Sparacino , C. and Kolber , A. 1980 . Ambient air pollutants: Collecting chemical characterization and mutagenicity testing . Mutat. Res. , 76 : 51 – 83 .
   PubMed Web of Science ®Google Scholar
• Jaurand , M. C. , Magne , L. , Boulmier , J. L. and Bignon , J. 1981 . In vitro reactivity of alveolar macrophages and red blood cells with asbestos fibres treated with oxalic acid, sulfur dioxide and benzo‐3,4‐pyrene . Toxicology , 21 : 323 – 342 .
   PubMed Web of Science ®Google Scholar
• Kandaswami , C. , Subrahmanyam , V. I. and O'Brien , T. J. PAHs, Physical and Biological Chemistry . 6th Int. Symp. The effect of asbestos on the bioac‐tivation of benzo(a)pyrene , Edited by: Cooke , M. , Dennis , A. J. and Fisher , G. L. pp. 389 – 403 . Columbus, Ohio : Battelle Press .
   Google Scholar
• Kaplan , J. and Keogh , E. 1982 . Temperature shifts induce the selective loss of alveolar macrophage plasma membrane components . J. Cell Biol. , 94 : 12 – 19 .
   PubMedGoogle Scholar
• Karnovsky , M. 1962 . Metabolic basis of phagocytic activity . Physiol. Rev. , 42 : 143
   PubMed Web of Science ®Google Scholar
• Kavet , R. , Brain , J. and Levens , D. 1978 . Characteristics of pulmonary macrophages lavaged from hamsters exposed to iron oxide aerosols . Lab. Invest. , 38 : 312 – 319 .
   PubMed Web of Science ®Google Scholar
• Lubawy , W. C. and Isaac , R. S. 1980 . Acute tobacco smoke exposure alters the profile of metabolites produced from benzo(a)pyrene by the isolated perfused rabbit lung . Toxicology , 18 : 37 – 47 .
   PubMed Web of Science ®Google Scholar
• McCord , J. and Fridovich , I. 1969 . Superoxide dismutase: An enzymatic function for erythrocu‐prein . J. Biol. Chem. , 244 : 6049 – 6055 .
   PubMed Web of Science ®Google Scholar
• McKeever , P. and Spicer , S. 1980 . “ Surface receptors of mononuclear phagocytes in the reticulo‐endothelial system ” . In Mononuclear Phagocytes , Edited by: Carr , I. and Daems , W. M. 220 – 225 . New York : Academic Press .
   Google Scholar
• Marshall , M. V. , McLemore , T. L. , Martin , R. R. , Jenkins , W. T. , Snodgrass , D. R. , Corson , M. A. , Arnott , M. S. , Wray , N. P. and Griffin , A. C. 1979 . Patterns of benzo(a)pyrene metabolism in normal human pulmonary alveolar macrophages . Cancer Lett. , 8 : 103 – 109 .
   PubMed Web of Science ®Google Scholar
• Morgan , D. D. , Warshawsky , D. , Niemeier , R. W. and Bingham , E. 1984 . The pharmacokinetics of benzo(a)pyrene in the isolated perfused rabbit lung: The influence of benzo(a)pyrene, n‐dodecane, particulate, or sulfur dioxide . Toxicology , 33 : 275 – 289 .
   PubMed Web of Science ®Google Scholar
• National Academy of Sciences . 1972 . “ Chemical reactivity of polycyclic aromatic hydrocarbons and aza‐arenes ” . In Biological Effects of Atmospheric Pollutants, Particulate Polycyclic Organic Matter , 63 – 81 . Washington, D.C. : National Academy of Sciences .
   Google Scholar
• Nelson , N. 1970 . “ Inhalation carcinogenesis in man: Environmental and occupational hazards ” . In Inhalation Carcinogenesis , USAEC Symposium Series 18 Edited by: Hanna , M. C. Jr. , Nettesheim , P. and Gilbert , J. R. 3 – 12 . Oak Ridge, Tenn.
   Google Scholar
• Niemeier , R. W. , Mulligan , L. T. and Rowland , J. 1986 . “ Cocarcinogenicity of foundry silica sand in hamsters ” . In Silica, Silicosis and Cancer: Controversy in Occupational Medicine , Edited by: Goldsmith , D. F. , Winn , D. M. and Shy , C. M. 215 – 227 . Philadelphia : Praeger .
   Google Scholar
• Perera , F. 1981 . Carcinogenicity of airborne fine particulate benzo(a)pyrene: An appraisal of the evidence and the need for control . Environ. Health Perspect. , 42 : 163 – 185 .
   PubMed Web of Science ®Google Scholar
• Pylev , L. , Roe , F. and Warurik , G. 1969 . Elimination of radioactivity after intratracheal installation of tritiated 3,4‐benzopyrene in hamsters . Br. J. Cancer , 23 : 103 – 115 .
   PubMed Web of Science ®Google Scholar
• Romert , L , Barnson , V. , Petterson , B. and Jenssen , D. 1985 . The evaluation of air sample extracts on the phagocytosis of alveolar macrophages and studies of macrophage‐mediated muta‐genesis in co‐cultivated V79 Chinese hamster cells . Environ. Int. , 11 : 341 – 346 .
   Google Scholar
• Rossi , F. , Romeo , D. and Patriarca , P. 1972 . Mechanism of phagocytosis associated oxidative metabolism in polymorphonuclear leucocytes and macrophages . J. Reticuloendothel. Soc. , 12 : 127
   PubMedGoogle Scholar
• Saffiotti , U. 1970 . “ Morphology of respiratory tumors inducted in Syrian golden hamsters ” . In Morphology of Experimental Respiratory Carcinogenesis , USAEC Symposium Series 21 Edited by: Nettesheim , P. , Hanna , M. G. Jr. and Deatherage , J. W. Jr. 245 – 254 . Oak Ridge, Tenn.
   Google Scholar
• Saffiotti , U. , Cefis , F. and Kolb , L. H. 1968 . A method for the experimental induction of broncho‐genie . Cancer Res. , 28 : 104 – 124 .
   PubMed Web of Science ®Google Scholar
• Saffiotti , U. , Stinson , S. F. , Keenan , K. P. and McDowell , E. M. 1985 . Tumor enhancement factors and mechanisms in the hamster respiratory tract carcinogenesis model . Carcinogenesis , 18 : 63 – 92 .
   Google Scholar
• Schreiber , H. , Martin , D. H. and Pazmino , N. 1975 . Species differences in the effect of benzo(a)pyrene‐ferric oxide on the respiratory tract of rats and hamsters . Cancer Res. , 35 : 1654 – 1661 .
   PubMed Web of Science ®Google Scholar
• Stenback , F. and Rowland , J. 1979 . Experimental respiratory carcinogenesis in hamsters: Environmental, physiochemical and biological aspects . Oncology , 36 : 63 – 71 .
   PubMedGoogle Scholar
• Stenback , F. , Rowland , J. and Sellakumar , A. 1976 . Carcinogenicity of benzo(a)pyrene and dusts in the hamster lung (instilled intratracheally with titanium oxide, aluminum oxide, carbon, and ferric oxide) . Oncology , 33 : 29 – 34 .
   PubMed Web of Science ®Google Scholar
• Sweeny , T. , Castranova , V. , Bowman , L. and Miles , P. 1981 . Factor which affects superoxide anion release from rat alveolar macrophages . Exp. Lung Res. , 2 : 85 – 96 .
   PubMedGoogle Scholar
• Teculescu , D. and Albu , A. 1973 . Pulmonary function in workers inhaling iron oxide dust . Int. Arch. Arbeitsmed. , 31 : 163 – 170 .
   PubMedGoogle Scholar
• Warshawsky , D. , Bingham , E. and Niemeier , R. W. 1983 . Influence of airborne particulate on the etabolism of benzo(a)pyrene in the isolated perfused lung . J. Toxicol. Environ. Health , 11 : 503 – 517 .
   PubMed Web of Science ®Google Scholar
• Warshawsky , D. , Bingham , E. and Niemeier , R. W. 1984 . The effects of cocarcinogen, ferric oxide, on the metabolism of benzo(a)pyrene in the isolated perfused lung . J. Toxicol. Environ. Health , 14 : 191 – 209 .
   PubMed Web of Science ®Google Scholar