80
Views
159
CrossRef citations to date
0
Altmetric
Original Articles

Chronic effects of atrazine on estrus and mammary tumor formation in female Sprague‐Dawley and Fischer 344 rats

, , , , , , & show all
Pages 169-182 | Received 20 Jul 1993, Accepted 23 Feb 1994, Published online: 19 Oct 2009

References

  • Boorman , G. A. , Wilson , J. T. , Van Zwieten , M. J. and Eustis , S. L. 1990 . “ Mammary gland ” . In Pathology of Fischer rat: Reference and atlas , Edited by: Boorman , G. , Eustis , S. L. , Elwell , M. , Montgomery , C. Jr. and Mckinney , W. F. 295 – 313 . New York : Academic Press .
  • Brawer , J. R. and Sonnenschein , C. 1975 . Cytopathological effects of estradiol on the arcuate nucleus of the female rat. A possible mechanism for pituitary tumorigenesis . Am. J. Anat. , 114 : 57
  • Cutts , J. H. and Noble , R. L. 1964 . Estrone‐induced mammary tumors in the rat. Induction and behavior of tumors . Cancer Res. , 24 : 1116 – 1123 .
  • Demarest , K. T. , Moore , K. E. and Riegle , G. D. 1985 . Adenohypophysial dopamine content and prolactin secretion in the aged male and female rat . Endocrinology , 116 : 1316 – 1323 .
  • Eldridge , J. C. , Tennant , M. K. , Wetzel , L. T. , Breckenridge , C. B. and Stevens , J. T. 1994 . Factors affecting mammary tumor incidence in chlorotriazine‐treated female rats: Hormonal properties, dosage, and animal strain . Environ. Health Perspect. , in press
  • Estes , K. S. , Simpkins , J. W. and Kahrs , S. P. 1982 . Normal CHRH neuronal function and hyperprolactinea in old pseudopregnant Fischer 344 rats . Neurobiol. Aging , 3 : 247 – 252 .
  • Farber , T. M. 1987 . Pesticide Assessment Guidelines, Subdivision F, Position Document: Selection of a Maximum Tolerated Dose (MTD) in Oncogenicity Studies , Toxicology Branch, Hazard Evaluation Division, Office of Pesticides Programs, U.S. Environmental Protection Agency . NTIS PD88–116736
  • Geschickter , C. F. and Byrnes , E. W. 1942 . Factors influencing the development and time of appearance of mammary cancer in the rat in response to estrogen . Arch. Pathol. , 33 : 334 – 356 .
  • Harman , S. M. and Talbert , G. B. 1985 . “ Aging of the reproductive system ” . In Handbook of the biology of aging , Edited by: Finch , C. E. and Schneider , E. I. 457 – 510 . New York : Van Nostrand Reinhold .
  • Huggins , C. 1965 . Two principles in therapy of cancers: Hormonal deprivation and hormonal interference . Cancer Res. , 25 : 1163 – 1167 .
  • Jaeger , B. R. 1984 . Pesticide Assessment Guidelines Subdivision F , (Revised Edition) , Hazard Evaluation: Human and Domestic Animals U.S. Environmental Protection Agency. Office of Pesticides and Toxic Substances. National Technical Information Service . NTIS PB86–108958
  • Lang , P. L. 1990 . Spontaneous Neoplastic Lesions in the CDF® (F‐344)/CRLBr Rat , 12 Charles River Laboratories .
  • Mahesh , V. B. , Muldoon , J. G. , Eldridge , J. C. and Korach , K. S. 1976 . The role of steroid hormones in the regulation of gonadotropin secretion . J. Steroid Biochem. , 6 : 1025 – 1036 .
  • McConnell , R. F. 1989 . “ General observations on the effects of sex steroids in rodents with emphasis on long‐term oral contraceptive studies ” . In Safety requirements for contraceptive steroids , Edited by: Michael , F. 211 – 229 . Cambridge : Cambridge University Press .
  • McMartin , D. N. , Sahota , P. S. , Gunson , D. E. , Han Hsu , H. and Spaet , R. H. 1992 . Neoplasms and related proliferative lesions in control Sprague‐Dawley rats from carcinogenicity studies. Historical data and diagnostic considerations . Toxicol. Pathol. , 20 : 212 – 225 .
  • Meites , J. 1972 . Relation of prolactin and estrogen to mammary tumorigenesis in the rat . J. Natl. Cancer Inst. , 48 : 1217 – 1223 .
  • Penz , M. T. and Huang , H. H. 1972 . Aging of hypothalamic‐pituitary‐ovarian function in the rats . Fertil. Steril. , 23 : 535 – 542 .
  • Russo , J. , Gusterson , B. A. , Rogers , A. E. , Russo , I. H. , Wellings , S. R. and Van Zweiten , M.J. 1990 . Comparative study of human and rat mammary tumorigenesis . Lab. Invest. , 62 : 244 – 278 .
  • Sarker , D. K. , Gottschall , P. E. and Meites , J. 1982 . Damage to hypothalmic dopaminergic neurons is associated with development of prolactin‐secreting pituitary tumours . Science , 218 : 684
  • Shafie , S. M. 1980 . Estrogen and growth of breast cancer. New evidence suggests indirect action . Science , 209 : 701 – 702 .
  • Snedecor , G. W. and Cochran , W. G. 1971 . Statistical methods, , 6th ed. , Ames : Iowa State University Press .
  • Stevens , J. T. , Breckenridge , C. B. , Wetzel , L. T. , Gillis , J. H. , Luempert , L. G. III and Eldridge , J. C. 1994 . Hypothesis for mammary tumorigenesis in Sprague‐Dawley rats exposed to certain triazine herbicides . J. Toxicol. Environ. Health , 43 : 139 – 153 .
  • Stevens , J. T. and Sumner , D. D. 1991 . “ Herbicides ” . In Handbook of pesticide toxicology , Edited by: Hayes , W. J. and Laws , E. R. Vol. 3 , 1317 – 1408 . San Diego : Academic Press .
  • Thakur , A. K. , Wetzel , L. T. and Stevens , J. T. 1990 . Statistical issues in lifetime oncogenicity studies in rodents . Proc. Biopharmaceutical Section of the American Statistical Association , : 275 – 281 .
  • Thompson , H. J. and Ronan , A. 1987 . The effect of D,L‐alpha‐difluoromethylornithine and endocrine manipulation on the induction of mammary carcinogenesis by 1 ‐methyl, 1‐nitrosurea . Carcinogenesis , 57 : 2003 – 2006 .
  • Uphouse , L. and Williams , J. 1989 . Sexual behavior of the intact female rat following o,p’‐DDT or p,p'‐ DDT . Reprod. Toxicol. , 3 : 33 – 41 .
  • Welsch , C. W. 1978 . Prolactin and the development and progression of early neoplastic mammary gland lesions . Cancer Res. , 38 : 4054 – 4058 .
  • Welsch , C. W. 1985 . Host factors affecting the growth of carcinogen‐induced mammary tumors: A review and tribute to Charles Brenton Huggins . Cancer Res. , 43 : 3415 – 3443 .
  • Welsch , C. W. , Brown , C. K. and Goodrich‐Smith , M. 1979 . Inhibition of mammary tumorigenesis in carcinogen‐treated Lewis rats by suppression of prolactin secretion . JNCI , 63 : 1211 – 1214 .
  • Wetzel , L. T. , Breckenridge , C. B. , Eldridge , J. C. , Tisdel , M. O. and Stevens , J. T. 1990 . Possible mechanism of mammary tumor formation in Sprague‐Dawley rats following the administration of chloro‐triazine herbicides . J. Am. Coll. Toxicol. , 8 (6) : 630
  • Wise , P. M. 1987 . The role of the hypothalamus in aging of the female reproductive system . J. Steroid Biochem. , 27 : 713 – 719 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.