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Invited review

Cadmium and prostate cancer

&
Pages 251-269 | Received 02 Feb 1994, Accepted 07 Apr 1994, Published online: 20 Oct 2009

References

  • Abd Elghany , N. , Schumacher , M. C. , Slattery , M. L. , West , D. W. and Lee , J. S. 1990 . Occupation, cadmium exposure and prostate cancer . Epidemiology , 1 : 107 – 115 .
  • Abshire , M. K. , Buzard , G. S. , Shiraishi , N. and Waalkes , M. P. 1994 . Induction of proto‐oncogene expression in rat L6 myoblasts by cadmium is inhibited by zinc preinduction of the metallothionein gene . Toxicologist , 14 : 163
  • Andersson , K. , Elinder , C.‐G. , Hogstedt , C. , Kjellstrom , T. and Spang , G. 1984 . Mortality among cadmium and nickel exposed workers in a Swedish battery factory . Toxicol. Environ. Chem. , 9 : 53 – 62 .
  • Bako , G. , Smith , E. S. O. , Hanson , J. and Dewar , R. 1982 . The geographical distribution of high cadmium concentrations in the environment and prostate cancer in Alberta . Can. J. Public Health , 73 : 92 – 96 .
  • Bataineh , Z. M. , Heidger , P. M. Jr. , Thompson , S. A. and Timms , B. G. 1986 . Immunocytochemical localization of metallothionein in the rat prostate gland . Prostate , 9 : 397 – 410 .
  • Battersby , S. , Chandler , J. A. and Morton , M. S. 1982 . The effect of orally administered cadmium on the ultrastructure of the rat prostate . Urol. Res. , 10 : 123 – 130 .
  • Blair , A. and Fraumeni , J. F. 1978 . Geographic patterns of prostate cancer in the United States . J. Natl. Cancer Inst. , 61 : 1379 – 1384 .
  • Bosland , M. C. 1987 . “ Adenocarcinoma, prostate, rat ” . In Genital systems , Edited by: Jones , T. C. , Mohr , U. and Hunt , R. D. 252 – 260 . New York : Springer‐Verlag .
  • Bosland , M. C. 1992 . Animal models for the study of prostate carcinogenesis . J. Cell. Biol. , 16H : 89 – 98 .
  • Bosland , M. C. 1994 . “ Male reproductive system ” . In Carcinogenesis: Target organ toxicology series , Edited by: Waalkes , M. P. and Ward , J. M. 339 – 402 . New York : Raven Press .
  • Bosland , M. C. and Prinsen , M. K. 1990 . Induction of dorsolateral prostate adenocarcinomas and other accessory sex gland lesions in male Wistar rats by a single administration of N‐methyl‐N‐nitroso‐urea, 7,12‐dimethylbenz(a)anthracene, and 3,2'‐dimethyl‐4‐aminobiphenyl after sequential treatment with cyproterone acetate and testosterone propionate . Cancer Res. , 50 : 691 – 699 .
  • Bosland , M. C. , Prinsen , M. K. and Kroes , R. 1983 . Adenocarcinomas of the prostate induced by N‐nitroso‐N‐methylurea in rats pretreated with cyproterone acetate and testosterone . Cancer Lett. , 18 : 69 – 78 .
  • Coffey , D. S. and Isaacs , J. T. 1980 . Requirements for an idealized animal model of prostatic cancer . Prog. Clin. Bio. Res. , 37 : 379 – 391 .
  • Coffey , D. S. and Isaacs , J. T. 1981 . Control of prostate growth . Urology (Suppl.) , 3 : 17
  • Coogan , T. P. , Bare , R. M. and Waalkes , M. P. 1992 . Cadmium‐induced DNA damage: Effects of zinc pretreatment . Toxicol. Appl. Pharmacol. , 113 : 227 – 233 .
  • Coogan , T. P. , Bare , R. M. , Bjomson , E. J. and Waalkes , M. P. 1994a . Enhanced metallothionein gene expression protects against cadmium‐induced genotoxicity in cultured rat liver cells . J. Toxicol. Environ. Health , 41 : 129 – 141 .
  • Coogan , T. P. , Shiraishi , N. and Waalkes , M. P. 1994b . Apparent quiescence of the metallothionein gene in the rat ventral prostate: Association with cadmium‐induced prostate tumors in rats . Environ. Health Perspect , in press
  • DeVita , V. T. , Hellman , S. and Rosenberg , S. A. , eds. 1982 . Cancer: Principles and practice of oncology , Philadelphia : Lippincott .
  • Donovan , M. P. , Schein , L. G. and Thomas , J. A. 1980 . Inhibition of androgen‐receptor interaction in mouse prostate gland cytosol by divalent metal ions . Mol. Pharmacol. , 17 : 156 – 162 .
  • Dubrow , R. and Wegman , D. H. 1984 . Cancer and occupation in Massachusetts: A death certificate study . Am. J. Ind. Med. , 6 : 207 – 230 .
  • Elinder , G.‐C. , Kjellstrom , T. , Hogstedt , C. , Andersson , K. and Spang , G. 1985 . Cancer mortality of cadmium workers . Br. J. Ind. Med. , 42 : 651 – 655 .
  • Fahim , M. S. and Khare , N. K. 1980 . Effects of subtoxic levels of lead and cadmium on urogenital organs of male rats . Arch. Androl. , 4 : 357 – 362 .
  • Feustel , A. and Wennrich , R. 1984a . Zinc and cadmium in cell fractions of prostatic cancer tissues of different histological grading in comparison to BPH and normal prostate . Urol. Res. , 12 : 147 – 150 .
  • Feustel , A. and Wennrich , R. 1984b . Determination of the distribution of zinc and cadmium in cellular fractions of BPH, normal prostate and prostatic cancers of different histologies by atomic and laser absorption spectrometry in tissue slices . Urol. Res. , 12 : 253 – 256 .
  • Feustel , A. , Wennrich , R. , Steiniger , D. and Klauss , P. 1982 . Zinc and cadmium concentration in pro‐static carcinoma of difference histological grading in comparison to normal prostate tissue and adenofibromyomatosis (BPH) . Urol. Res. , 10 : 301 – 303 .
  • Feustel , A. , Wennrich , R. and Dittrich , H. 1987 . Zinc, cadmium and selenium concentrations in separated epithelium and stroma from prostatic tissues of different histology . Urol. Res. , 15 : 161 – 163 .
  • Flanders , W. D. 1984 . Review: Prostate cancer epidemiology . Prostate , 5 : 621 – 629 .
  • Friberg , L. , Elinder , C.‐G. , Kjellström , T. and Nordberg , G. F. 1986 . Cadmium and health: A toxicological and epidemiological appraisal , Vols. I and II , Boca Raton, Fla. : CRC Press .
  • Goering , P. L. , Waalkes , M. P. and Klaassen , C. D. 1994 . “ Cadmium toxicity ” . In Handbook of experimental pharmacology; Toxicology of metals, biochemical effects , Edited by: Goyer , R. A. and Cherian , M. G. New York : Springer‐Verlag . in press
  • Gunn , S. A. and Gould , T. C. 1970 . “ Cadmium and other mineral elements ” . In The testis Vol. III, Influencing factors , Edited by: Johnson , A. D. , Gomes , W. R. and Vandemark , N. L. Vol. III , 377 – 481 . New York : Academic Press .
  • Gunn , S. A. , Gould , T. C. and Anderson , W. A. D. 1963 . Cadmium‐induced interstitial‐cell tumors in rats and mice and their prevention by zinc . J. Natl. Cancer Inst. , 31 : 745 – 753 .
  • Gunn , S. A. , Gould , T. C. and Anderson , W. A. D. 1964 . Effect of zinc on cancerogenesis by cadmium . Proc. Soc. Exp. Biol. Med. , 115 : 653 – 657 .
  • Gunn , S. A. , Gould , T. C. and Anderson , W. A. D. 1967 . Specific response of mesenchymal tissue to cancerogenesis by cadmium . Arch. Pathol. , 83 : 493 – 499 .
  • Habib , F. K. , Hammond , G. L. , Lee , I. R. , Dawson , J. B. , Mason , M. K. , Smith , P. H. and Stitch , S. R. 1976 . Metal‐androgen interrelationships in carcinoma and hyperplasia of the human prostate . J. Endocrinol. , 71 : 133 – 141 .
  • Haddow , A. , Roe , F. J. C. , Dukes , C. E. and Mitchley , B. C. V. 1964 . Cadmium neoplasia: Sarcomata at the site of injection of cadmium sulphate in rats and mice . Br. J. Cancer , 18 : 667 – 673 .
  • Hayashi , N. , Sugimura , Y. , Kawamura , J. , Donjacour , A. A. and Cunha , G. R. 1991 . Morphological and functional heterogeneity in the rat prostatic gland . Biol. Reprod. , 45 : 308 – 321 .
  • Heath , J. C. , Daniel , I. R. , Dingle , J. T. and Webb , M. 1962 . Cadmium as a carcinogen . Nature , 193 : 592 – 593 .
  • Hebel , R. and Stromberg , M. W. 1976 . “ Accessory genital glands ” . In Anatomy of the laboratory rat , 70 – 71 . Baltimore : Williams & Wilkins .
  • Hochadel , J. F. , Shiraishi , N. , Coogan , T. P. , Koropatnick , J. and Waalkes , M. P. 1994 . Cadmium‐induced genotoxicity in the absence of cytotoxicity in rat testicular cells is associated with minimal activity of the metallothionein gene . Toxicologist , 14 : 236
  • Hoffmann , L. , Putzke , H.‐P. , Simonn , C. , Gase , P. , Russbült , R. , Kampehl , H.‐J. , Erdmann , T. and Huckstorf , C. 1985a . Spielt Kadmium eine Rolle in der Ätiologie und Pathogenese des Prostatakarzinoms . Z. Ges. Hyg. , 31 : 224 – 227 .
  • Hoffmann , L. , Putzke , H.‐P. , Kampehl , H.‐J. , Russbült , R. , Gase , P. , Simonn , C. , Erdmann , T. and Huckstorf , C. 1985b . Carcinogenic effects of cadmium on the prostate of the rat . J. Cancer Res. Clin. Oncol. , 109 : 193 – 199 .
  • Hoffmann , L. , Putzke , H.‐P. , Bendel , L. , Erdmann , T. and Huckstorf , C. 1988 . Electron microscopic results on the ventral prostate of the rat after CdCl2 administration. A contribution towards etiology of the cancer of the prostate . J. Cancer Res. Clin. Oncol. , 114 : 273 – 278 .
  • Holden , H. A mortality study of workers exposed to cadmium fumes . Proc. 2nd Int. Cadmium Conf. February 6–8 , Cannes. pp. 211 – 216 . London : Cadmium Association .
  • Holden , H. Further mortality studies on workers exposed to cadmium fumes . Seminar on Occupational Exposure to Cadmium . pp. 23 – 24 . London : Cadmium Association .
  • Hoover , D. M. , Best , K. L. , McKenney , B. K. , Tamura , R. M. and Neubauer , B. L. 1990 . Experimental induction of neoplasia in the accessory sex organs of male Lobund‐Wistar rats . Cancer Res. , 50 : 142 – 146 .
  • IARC . 1976 . Cadmium, nickel, some epoxides, miscellaneous industrial chemicals and general considerations on volatile anesthetics , IARC Monogr. 11 39 – 74 . Lyon : IARC .
  • IARC . 1994 . Cadmium, mercury, beryllium and the glass industry , IARC Monogr. 58 Lyon : IARC .
  • Kazantzis , G. and Blanks , R. G. A mortality study of cadmium exposed workers . 7th Int. Cadmium Conf. Edited by: Cook , M. E. , Hiscock , S. A. , Morrow , H. and Volpe , R. A. pp. 150 – 157 . London : Cadmium Association .
  • Kazantzis , G. , Lam , T.‐H. and Sullivan , K. R. 1988 . The mortality of cadmium‐exposed workers; A five‐year update . Scand. J. Environ. Health , 14 : 220 – 223 .
  • Kipling , M. D. and Waterhouse , J. A. H. 1967 . Cadmium and prostatic carcinoma . Lancet , i : 730 – 731 .
  • Kjellstrom , T. , Friberg , L. and Rahnster , B. 1979 . Mortality and cancer morbidity among cadmium‐exposed workers . Environ. Health Perspect. , 28 : 199 – 204 .
  • Kolonel , L. and Winkelstein , W. Jr. 1977 . Cadmium and prostatic carcinoma . Lancet , 10 : 566 – 567 .
  • Lahtonen , R. 1985 . Zinc and cadmium concentrations in whole tissue and in separated epithelium and stroma from human benign prostatic hypertropic glands . Prostate , 6 : 177 – 183 .
  • Laskey , J. W. , Rehnberg , G. L. , Laws , S. C. and Hein , J. F. 1984 . Reproductive effects of low acute doses of cadmium chloride in adult male rats . Toxicol. Appl. Pharmacol. , 73 : 250 – 255 .
  • Lernen , R. A. , Lee , J. S. , Wagoner , J. K. and Blejer , H. P. 1976 . Cancer mortality among cadmium production workers . Ann. NY Acad. Sci. , 271 : 273 – 279 .
  • Lindegaard , P. M. , Hansen , S. O. , Christensen , J. E. J. , Anderson , B. B. and Andersen , O. 1990 . The distribution of cadmium within the human prostate . Biol. Trace Elem. Res. , 25 : 97 – 104 .
  • McNeal , J. E. 1993 . Prostatic microcarcinomas in relation to cancer origin and the evolution to clinical cancer . Cancer (Suppl.) , 71 : 984 – 991 .
  • McNeal , J. E. , Reese , J. H. , Redwine , E. A. , Freiha , F. S. and Stamey , T. A. 1986 . Cribriform adenocarcinoma of the prostate . Cancer , 58 : 1714 – 1719 .
  • Nishimura , H. , Nishimura , N. and Tohyama , C. 1990 . Localization of metallothionein in the genital organs of the male rat . J. Histochem. Cytochem. , 38 : 927 – 933 .
  • Noble , R. L. 1977 . The development of prostatic adenocarcinoma in Nb rats following prolonged sex hormone administration . Cancer Res. , 37 : 1929 – 1933 .
  • Ogunlewe , J. O. and Osegbe , D. N. 1989 . Zinc and cadmium concentrations in indigenous blacks with normal, hypertrophie, and malignant prostate . Cancer , 63 : 1388 – 1392 .
  • Piscator , M. 1981 . Role of cadmium in carcinogenesis with special reference to cancer of the prostate . Environ. Health Perspect. , 40 : 107 – 120 .
  • Pollard , M. and Luckert , P. H. 1992 . Early manifestations of induced prostate tumors in Lobund‐Wistar rats . Cancer Lett. , 67 : 113 – 116 .
  • Potts , C. L. 1965 . Cadmium proteinuria—The health of battery workers exposed to cadmium oxide dust . Ann. Occup. Hyg. , 8 : 55 – 61 .
  • Pour , P. P. and Stepan , K. 1987 . Induction of prostatic carcinomas and lower urinary tract neoplasms by combined treatment of intact and castrated rats with testosterone propionate and N‐nitrosobis(2‐oxopropyl)amine . Cancer Res. , 47 : 5699 – 5706 .
  • Prasad , A. S. 1982 . “ Clinical and biochemical spectrum on zinc deficiency in human subjects ” . In Clinical, biochemical, and nutritional aspects of trace elements , Edited by: Prasad , A. S. 3 New York : Liss .
  • Price , D. 1963 . Comparative aspects of development and structure in the prostate . Monogr. Natl. Cancer Inst. , 12 : 1 – 25 .
  • Roe , F. J. C. , Dukes , C. E. , Cameron , K. I. , Pugh , R. C. B. and Mitchley , B. C. V. 1964 . Cadmium neoplasia: Testicular atrophy and Leydig cell hyperplasia and neoplasia in rats and mice following subcutaneous injection of cadmium salts . Br. J. Cancer , 18 : 674 – 681 .
  • Ross , R. K. , Shimizu , H. , Paganini‐Hill , A. , Honda , G. and Henderson , B. E. 1987 . Case‐control studies of prostate cancer in blacks and whites in southern California . JNCI , 78 : 869 – 874 .
  • Scardino , P. T. , Weaver , R. and Huson , M. A. 1992 . Early detection of prostate cancer . Hum. Pathol. , 23 : 211 – 222 .
  • Scott , R. and Aughey , R. 1978 . Methylcholanthrene and cadmium induced changes in rat prostate . Br. J. Urol. , 50 : 25 – 28 .
  • Shirai , T. , Fukushima , S. , Ikawa , E. , Tagawa , Y. and Ito , N. 1986 . Induction of prostate carcinoma in situ at high incidence in F344 rats by a combination of 3,2'‐dimethyl‐4‐aminobiphenyl and ethinyl estradiol . Cancer Res. , 46 : 6423 – 6426 .
  • Shirai , T. , Tagawa , Y. , Taguchi , O. , Ikawa , E. , Mutai , M. , Fukushima , S. and Ito , N. 1988 . Lowtumorigenic response to 3,2'‐dimethyl‐4‐aminobiphenyl administration in the prostate of rats castrated at birth . Jpn. J. Cancer Res. , 79 : 1293 – 1296 .
  • Shirai , T. , Imaida , K. , Iwasaki , S. , Mori , T. , Tada , M. and Ito , N. 1993a . Sequential observation of rat prostate lesion development induced by 3,2'‐dimethyl‐4‐aminobiphenyl and testosterone . Jpn. J. Cancer Res. , 84 : 20 – 25 .
  • Shirai , T. , Iwasaki , S. , Masui , T. , Mori , T. , Kato , T. and Ito , N. 1993b . Enhancing effect of cadmium on rat ventral prostate carcinogenesis induced by 3,2'‐dimethyl‐4‐aminobiphenyl . Jpn. J. Cancer Res. , 84 : 1023 – 1030 .
  • Sinquin , G. , Morfin , R. F. , Charles , J.‐F. and Floch , H. H. 1984 . Testosterone metabolism by homogenates of human prostates with benign hyperplasia: Effects of zinc, cadmium and other bivalent cations . J. Steroid Biochem. , 20 : 773 – 780 .
  • Sorahan , T. and Waterhouse , J. A. H. 1985 . Cancer of the prostate among nickel‐cadmium battery workers (letter) . Lancet , i : 459
  • Stayner , L. , Smith , R. , Thun , M. , Schorr , T. and Lernen , R. 1992 . A dose‐response analysis and quantitative assessment of lung cancer risk and occupational cadmium exposure . Ann. Epidemiol. , 2 : 177 – 194 .
  • Stephens , T. 1991 . A mixed bag of cancer trends . J. Natl, Inst. Health Res. , 3 : 71 – 72 .
  • Suzuki , T. , Umeyama , T. , Ohma , C. , Yamanaka , H. , Suzuki , K. , Nakajima , K. and Kimura , M. 1991 . Immunohistochemical study of metallothionein in normal and benign prostatic hyperplasia of human prostate . Prostate , 19 : 35 – 42 .
  • Suzuki , T. , Yamanaka , H. , Nakajima , K. , Kanatani , K. , Suzuki , K. , Kimura , M. , Nakazawa , Y. and Otaki , N. 1993 . Induction of metallothionein by CdCl2 administration in rat prostate . Prostate , 22 : 163 – 170 .
  • Takenaka , S. , Oldiges , H. , König , H. , Hochrainer , D. and Oberdörster , G. 1983 . Carcinogenicity of cadmium chloride aerosols in Wistar rats . JNCI , 70 : 367 – 373 .
  • Terracio , L. and Nachtigal , M. 1986 . Transformation of prostatic epithelial cells and fibroblasts with cadmium chloride in vitro . Arch. Toxicol. , 58 : 141 – 151 .
  • Terracio , L. and Nachtigal , M. 1988 . Oncogenicity of rat prostate cells transformed in vitro with cadmium chloride . Arch. Toxicol. , 61 : 450 – 456 .
  • Thomas , J. A. , Donovan , M. P. , Waalkes , M. P. and Curto , K. A. 1981 . “ Some protein‐heavy metal interactions in the rodent prostate cell ” . In The prostatic cell , Edited by: Murphy , G. P. , Sandberg , A. A. and Karr , J. P. 459 – 474 . New York : Alan A. Liss .
  • Thun , M. J. , Schnorr , T. M. , Smith , A. B. , Halperin , W. E. and Lernen , R. A. 1985 . Mortality among a cohort of US cadmium production workers—An update . JNCI , 74 : 325 – 333 .
  • Timms , B. G. and Hagen , J. A. 1989 . Immunohistochemical localization of metallothionein in the rat prostate gland during postnatal development . Prostate , 14 : 367 – 382 .
  • Tohyama , C. , Suzuki , J. S. , Homma , N. , Nishimura , N. and Nishimura , H. 1993 . “ Regulation of metallothionein biosynthesis in genital organs of male rats ” . In Metallothionein III , Edited by: Suzuki , K. T. , Imura , N. and Kimura , M. 443 – 457 . Basel, , Switzerland : Birkhäuser Verlag .
  • Umeyama , T. , Saruki , K. , Imai , K. , Hidetoshi , Y. , Suzuki , K. , Ikei , N. , Kodaira , T. , Nakajima , K. , Saitoh , H. and Kimura , M. 1987 . Immunohistochemical demonstration of metallothionein in the rat prostate . Prostate , 10 : 257 – 264 .
  • Visser , A. J. and Deklerk , J. N. 1979 . The effect of dietary cadmium on prostate growth . Trans. Am. Assoc. Genito‐Urinary Surg. , 70 : 66 – 68 .
  • Waalkes , M. P. and Goering , P. L. 1990 . Metallothionein and other cadmium‐binding proteins: Recent developments . Chem. Res. Toxicol. , 3 : 281 – 288 .
  • Waalkes , M. P. and Klaassen , C. D. 1984 . Postnatal ontogeny of metallothionein in various organs of the rat . Toxicol. Appl. Pharmacol. , 74 : 314 – 320 .
  • Waalkes , M. P. and Oberdörster , G. 1990 . “ Cadmium carcinogenesis ” . In Biological effects of heavy metals, Vol. II, Metal carcinogenesis , Edited by: Foulkes , E. C. Vol. II , 129 – 157 . Boca Raton, Fla. : CRC Press .
  • Waalkes , M. P. and Perantoni , A. 1989 . Apparent deficiency of metallothionein in the Wistar rat prostate . Toxicol. Appl. Pharmacol. , 101 : 83 – 94 .
  • Waalkes , M. P. and Rehm , S. 1992 . Carcinogenicity of oral cadmium in the male Wistar (WF/NCr) rat: Effect of chronic dietary zinc deficiency . Fundam. Appl. Toxicol. , 19 : 512 – 520 .
  • Waalkes , M. P. , Rehm , S. , Riggs , C. W. , Bare , R. M. , Devor , D. E. , Poirier , L. A. , Wenk , M. L. , Henneman , J. R. and Balaschak , M. S. 1988 . Cadmium carcinogenesis in the male Wistar [Crl:(WI)BR] rats: Dose‐response analysis of tumor induction in the prostate and testes and at the injection site . Cancer Res. , 48 : 4656 – 4663 .
  • Waalkes , M. P. , Rehm , S. , Riggs , C. W. , Bare , R. M. , Devor , D. E. , Poirier , L. A. , Wenk , M. L. and Henneman , J. R. 1989 . Cadmium carcinogenesis in the male Wistar [Crl:(WI)BR] rats: Dose‐response analysis of effects of zinc on tumor induction in the prostate and in the testes and at the injection site . Cancer Res. , 49 : 4282 – 4288 .
  • Waalkes , M. P. , Coogan , T. P. and Barter , R. A. 1992a . Toxicological principles of metal carcinogenesis with special emphasis on cadmium . Crit. Rev. Toxicol. , 22 : 175 – 201 .
  • Waalkes , M. P. , Rehm , S. , Perantoni , A. and Coogan , T. P. 1992b . “ Cadmium exposure in rats and tumors of the prostate ” . In Cadmium in the human environment: Toxicity and carcinogenicity , Edited by: Nordberg , G. F. , Alessio , L. and Herber , R. F. M. 390 – 400 . Lyon : IARC .
  • Waalkes , M. P. , Rehm , S. , Sass , B. , Kovatch , R. and Ward , J. M. 1994 . Chronic carcinogenesis and toxic effects of a single subcutaneous dose of cadmium in male NFS and C57 mice and male Syrian hamsters . Toxic Subst J. , 13 : 15 – 28 .
  • Webber , M. M. 1985a . Selenium prevents the growth stimulatory effects of cadmium on human prostatic epithelium . Biochem. Biophys. Res. Commun. , 127 : 871 – 877 .
  • Webber , M. M. 1985b . “ Normal, benign and malignant human prostatic epithelium: In vitro cell models for studies on the etiology, treatment, and prevention of benign and malignant human prostatic neoplasia ” . In In vitro models for cancer research: Carcinoma of the prostate and testis , Edited by: Webber , M. M. and Sekely , L. I. 25 – 41 . Boca Raton, Fla. : CRC Press .
  • Wernert , N. , Goebbels , R. , Bonkhoff , H. and Dhom , G. 1990 . Squamous cell carcinoma of the prostate . Histopathology , 17 : 339 – 344 .
  • West , D. W. , Slattery , M. L. , Robison , L. M. , French , T. K. and Mahoney , A. W. 1991 . Adult dietary intake and prostate cancer risk in Utah: A case‐control study with special emphasis on aggressive tumors . Cancer Causes Control , 2 : 85 – 94 .
  • Wilbourn , J. , Haroun , L. , Heseltine , E. , Kaldor , J. , Partensky , C. and Vainio , H. 1986 . Response of experimental animals to human carcinogens: an analysis based upon the IARC Monographs programme . Carcinogenesis , 7 : 1853 – 1863 .

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