22
Views
27
CrossRef citations to date
0
Altmetric
Original Articles

PCB congeners in the rat brain: Selective accumulation and lack of regionalization

, &
Pages 453-468 | Received 04 Feb 1994, Accepted 20 May 1994, Published online: 19 Oct 2009

References

  • Abdel‐Hamid , F. M. , Moore , L. A. and Matthews , H. B. 1981 . Comparative study of 3,4,3’,4'‐tetra‐chlorobiphenyl in male and female rats and female monkeys . J. Toxicol. Environ. Health , 7 : 181 – 191 .
  • Agrawal , A. K. , Tilson , H. A. and Bondy , S. C. 1981 . 3,4,3’,4'‐Tetrachlorobiphenyl given to mice prenatally produces long‐term decreases in striatal dopamine and receptor binding sites in the caudate nucleus . Toxicol. Lett. , 7 : 417 – 424 .
  • Albro , P. W. and Parker , C. E. 1979 . Comparison of the composition of Aroclor 1242 and Aroclor 1016 . J. Chiromatogr. , 169 : 161 – 166 .
  • Ballschmiter , K. and Zell , M. 1980 . Analysis of PCBs by glass capillary gas chromatography: Comparison of technical Aroclor and Clophen mixtures . Fresenius Z. Anal. Chem. , 302 : 20 – 31 .
  • Brouwer , A. and van den Berg , K. J. 1986 . Binding of a metabolite of 3,4,3’,4'‐tetrachlorobiphenyl to transthyretin reduces serum vitamin A transport by inhibiting the formation of the protein complex carrying both retinol and thyroxin . Toxicol. Appl. Pharmacol. , 85 : 301 – 312 .
  • Bush , B. , Snow , J. , Connor , S. and Koblintz , R. 1985 . Polychlorinated biphenyl congeners, p,p'‐DDE, and hexachlorobenzene in maternal and fetal cord blood from mothers in upstate New York . Arch. Environ. Contam. Toxicol. , 14 : 443 – 450 .
  • Chen , Y.‐C. , Guo , Y.‐L. , Hsu , C.‐C. and Rogan , W. J. 1992 . Cognitive development of yu‐cheng ("oil disease") children prenatally exposed to heat‐degraded PCBs . J. Am. Med. Assoc. , 268 (22) : 3213 – 3218 .
  • Hansen , L. G. , Byerly , C. S. , Metcalf , R. L. and Bevill , R. F. 1975 . Effect of a polychlorinated biphenyl mixture on swine reproduction and tissue residues . Am. J. Vet. Res. , 36 (1) : 23 – 26 .
  • Hoar , R. M. and Monie , I. W. 1981 . “ Comparative development of specific organ systems ” . In Developmental toxicology , Edited by: Kimmel , C. A. and Buelke‐Sam , J. 13 – 33 . New York : Raven Press .
  • Jacobson , J. L. , Jacobson , S. W. and Humphrey , H. E. B. 1990a . Effects of in utero exposure to polychlorinated biphenyls and related contaminants on cognitive functioning in young children . J. Pediatr. , 116 : 38 – 45 .
  • Jacobson , J. L. , Jacobson , S. W. and Humphrey , H. E. B. 1990b . Effects of exposure to PCBs and related compounds on growth and activity of children . Neurotoxicol. Teratol. , 12 : 319 – 326 .
  • Matthews , H. B. , Surles , J. R. , Carver , J. G. and Anderson , M. W. 1977 . Polychlorinated biphenyl transport by blood components . Toxicol. Appl. Pharmacol. , 41 : 201
  • McFarland , V. A. and Clarke , J. U. 1989 . Environmental occurrence, abundance, and potential toxicity of polychlorinated biphenyl congeners: Considerations for a congener‐specific analysis . Environ. Health Perspect. , 81 : 225 – 239 .
  • Palkovits , M. and Brownstein , M. J. 1988 . Maps and guide to microdissection of the rat brain , New York : Elsevier .
  • Rogan , W. J. , Gladen , B. C. , Hung , K. , Koong , S. , Shih , L. , Taylor , J. S. , Wu , Y. , Yang , D. , Ragan , N. B. and Hsu , C. 1988 . Congenital poisoning by polychlorinated biphenyls and their contaminants in Taiwan . Science , 241 : 334 – 336 .
  • Seegal , R. F. , Brosch , K. O. and Bush , B. 1986 . Regional alterations in serotonin metabolism induced by oral exposure of rats to polychlorinated biphenyls . Neurotoxicology , 7 (1) : 155 – 166 .
  • Seegal , R. F. , Bush , B. and Shain , W. 1990 . Lightly chlorinated ortho‐substituted PCB congeners decrease dopamine in nonhuman primate brain and tissue culture . Toxicol. Appl. Pharmacol. , 106 : 135 – 144 .
  • Seegal , R. F. , Bush , B. and Brosch , K. O. 1991a . Comparison of effects of Aroclors 1016 and 1260 on nonhuman primate catecholamine function . Toxicology , 66 : 145 – 163 .
  • Seegal , R. F. , Bush , B. and Brosch , K. O. 1991b . Sub‐chronic exposure of the adult rat to Aroclor 1254 yields regionally‐specific changes in central dopaminergic function . Neurotoxicology , 12 : 55 – 66 .
  • Shain , W. , Overmann , S. R. , Wilson , L. R. , Kostas , J. and Bush , B. 1986 . A congener analysis of polychlorinated biphenyls accumulating in rat pups after perinatal exposure . Arch. Environ. Contam. Toxicol. , 15 : 687 – 707 .
  • Shain , W. , Bush , B. and Seegal , R. 1991 . Neurotoxicity of polychlorinated biphenyls: Structure‐activity relationship of individual congeners . Toxicol. Appl. Pharmacol. , 111 : 33 – 42 .
  • Shimada , T. and Sawabe , Y. 1983 . Activation of 3,4,3’,4'‐tetrachlorobiphenyl to protein‐bound metabolites by rat liver microsomal cytochrome P‐448‐containing monooxygenase system . Toxicol. Appl. Pharmacol. , 70 : 486 – 493 .
  • Sipes , I. G. and Schnellmann , R. G. 1987 . “ Biotransformation of PCBs: Metabolic pathways and mechanisms ” . In Polychlorinated biphenyls (PCBs): Mammalian and environmental toxicology , Edited by: Safe , S. and Hutzinger , O. 97 – 110 . Heidelberg, , Germany : Springer‐Verlag .
  • Tilson , H. A. , Jacobson , J. L. and Rogan , W. J. 1990 . Polychlorinated biphenyls and the developing nervous system: Cross‐species comparisons . Neurotoxicol. Teratol. , 12 : 239 – 248 .
  • Vomachka , M. S. , Vodicnik , M. J. and Lech , J. J. 1983 . Characteristics of 2,4,5,2’,4’,5'‐hexachlorobiphenyl distribution among lipoproteins in vitro . Toxicol. Appl. Pharmacol. , 70 : 350 – 361 .
  • Yoshimura , H. , Yonemoto , Y. , Yamada , H. , Koga , N. , Oguri , K. and Saeki , S. 1987 . Metabolism in vivo of 3,3’,4,4'‐tetrachlorobiphenyl and toxicological assessment of the metabolites in rats . Xenobiotica , 17 : 897 – 910 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.