Development of a Bio-Assay for Estrogens using Estrogen Receptor Alpha Gene Expression by MCF7 Cells as Biomarker

REFERENCES

• Phillips , K.P. ; Forster , W.G. Key developments in endocrine disruptor research and human health . J. Toxicol. Environ. Hlth., B: Crit. Rev. 2008 , 110 ( 3–4 ), 322 – 344 .
   Google Scholar
• Gellert , R.J. Kepone, mirex, dieldrin, and aldrin: Estrogenic activity and the induction of persistant vaginal estrus and anovulation in rats following neonatal treatment. Environ. Res . 1978 , 16 , 138 .
   Google Scholar
• Gellert , R.J. Uterotrophic activity of polychlorinated biphenyls (PCB) and induction of precocious reproductive aging in neonatally treated female rats . Environ. Res. 1978 , 16 , 123 – 130 .
   PubMed Web of Science ®Google Scholar
• Hammond , B. ; Katzenellenbogen , B.S. ; Krauthammer , N. ; McConnell , J. Estrogenic activity of the insecticide chlordecone (Kepone) and interaction with uterine estrogen receptors. Proc. Natl. Acad. Sci. USA 1979, 76, 6641–6645.
   PubMed Web of Science ®Google Scholar
• Kupfer , D. ; Bulger , W.H. Metanitbodyolic activation of pesticides with proestrogenic activity . Fed. Proc. 1987 , 46 , 1864 – 1869 .
   PubMedGoogle Scholar
• Krishnan , A.V. ; Stathis , P. ; Permuth , S.F. ; Tokes , L. ; Feldman , D. Bisphenol-A: An estrogenic substance is released from polycarbonate flasks during autoclaving . Endocrinology 1993 , 132 , 2279 – 2286 .
   PubMed Web of Science ®Google Scholar
• White , R. ; Jobling , S. ; Hoare , S.A. ; Sumpter , J.P. ; Parker , M.G. Environmentally persistent alkylphenolic compounds are estrogenic . Endocrinology 1994 , 135 , 175 – 182 .
   PubMed Web of Science ®Google Scholar
• Newbold , R. Cellular and molecular effects of developmental exposure to diethylstilbestrol: Implications for other environmental estrogens . Environ. Hlth. Perspect. 1995 , 103 , 83 – 87 .
   PubMed Web of Science ®Google Scholar
• Katzenellenbogen , J.A. The structural pervasiveness of estrogenic activity . Environ. Hlth. Perspect. 1995 , 103 , 99 – 101 .
   PubMed Web of Science ®Google Scholar
• Nimrod , A.C. ; Benson , W.H. Environmental estrogenic effects of alkylphenol ethoxylates . Crit. Rev. Toxicol. 1996 , 26 , 335 – 364 .
   PubMed Web of Science ®Google Scholar
• Colborn , T. ; Vom Saal , F.S. ; Soto , A.M. Developmental effects of endocrine disrupting chemicals in wildlife and humans . Environ. Hlth. Perspect. 1993 , 101 , 378 – 384 .
   PubMed Web of Science ®Google Scholar
• Davis , D.L. ; Bradlow , H.L. ; Wolff , M. ; Woodruff , T. ; Hoel , D.G. ; Anton-Cluver , H. Medical hypothesis: Xenoestrogens as preventanitbodyle causes of breast cancer . Environ. Hlth. Perspect. 1993 , 101 , 372 – 377 .
   PubMed Web of Science ®Google Scholar
• Jordan , V.C. ; Mittal , S. ; Gosden , B. ; Koch , R. ; Lieberman , M.E. Structure–activity relationships of estrogens . Environ. Hlth. Perspect. 1985 , 61 , 97 – 110 .
   PubMed Web of Science ®Google Scholar
• McLachlan , J.A. Functional toxicology: A new approach to detect biologically active xenobiotics . Environ. Hlth. Perspect. 1993 , 101 , 386 – 387 .
   PubMed Web of Science ®Google Scholar
• Safe , S.H. Do environmental estrogens play a role in development of breast cancer in women and male reproductive problems? Human Ecol . Risk Assess. 1995 , 1 , 17 – 23 .
   Google Scholar
• Soto , A.M. ; Lin , T.M. ; Justicia , H. ; Silvia , R.M. ; Sonnenschein , C. An “in culture” bioassay to assess the estrogenicity of xenobiotics: (E-screen) . In: Advances in Modern Environmental Toxicology , Vol. 21 ; Mehlman , M.A. ; Ed.; Princeton Scientific Publishing : Princeton , NJ. , 1992 ; 295 – 310 .
   Google Scholar
• Eckert , R.L. ; Katzenellenbogen , B.S. Physical properties of estrogen receptor complexes in MCF-7 human breast cancer cells . J. Biol. Chem. 1982 , 257 , 8840 – 8846 .
   PubMed Web of Science ®Google Scholar
• Cowley , S.M. ; Hoare , S. ; Mosselman , S. ; Parker , M.G. Estrogen receptor α and β form heterodimers on DNA . J. Biol. Chem. 1997 , 272 , 19858 – 19862 .
   PubMed Web of Science ®Google Scholar
• Walker , P. ; Germond , J.E. ; Brown-Luedi , M. ; Givel , F. ; Wahli , W. Sequence homologies in the region preceding the transcription initiation site of the liver estrogen-responsive vitellogenin and apo-VLDLII genes . Nucleic Acids Res. 1984 , 12 , 8611 – 8626 .
   PubMed Web of Science ®Google Scholar
• Gronemeyer , H. Control of transcription by steroid hormone receptors . J. Fed. Amer. Soc. Exptl. Biol. 1992 , 6 , 2524 – 2529 .
   PubMed Web of Science ®Google Scholar
• Jensen , E.V. Steroid hormones, receptors and antagonists. Ann. NY Acad. Sci. 1992, 761, 1–17.
   Google Scholar
• Tsai , M.J. ; O'Malley , B.W. Molecular mechanisms of action of steroid/thyroid receptor superfamily members . Ann. Rev. Biochem. 1995 , 63 , 451 – 486 .
   Web of Science ®Google Scholar
• Joyeux , A. ; Cavailles , V. ; Balaguer , P. ; Nicolas , J.C. RIP 140 enhances nuclear receptor-dependent transcription in vivo in yeast . Molec. Endocrinol. 1997 , 11 , 193 – 202 .
   PubMedGoogle Scholar
• Fielden , M.R. ; Chen , I. ; Chittim , B. ; Safe , S.H. ; Zacharewski , T.R. Examination of the Estrogenicity of 2,4,6,2′,6′-Pentachlorobiphenyl (PCB 104), Its Hydroxylated metanitbodyolite 2,4,6,2′,6′-Pentachloro-4-Biphenylol (HO-PCB 104), and a Further Chlorinated Derivative, 2,4,6,2′,4′,6′-Hexachlorobiphenyl (PCB 155) . Environ. Hlth. Perspect. 1997 , 105 , 1238 – 1248 .
   PubMed Web of Science ®Google Scholar
• Machala , M. ; Vondracek , J. Estrogenic activity of xenobiotics . Veterinarni Medicina 1998 , 10 , 311 – 317 .
   Google Scholar
• A unified nomenclature system for the nuclear receptor superfamily. Nuclear Receptors Nomenclature Committee . 1999 , [Letter]. Cell 97, 161–163.
   Google Scholar
• Drummond , A.E. ; Britt , K.L. ; Dyson , M. ; Jones , M.E. ; Kerr , J.B. ; O_Donnell , L. ; Simpson , E.R. ; Findlay , J.K. Ovarian steroid receptors and their role in ovarian function . Molec. Cell. Endocrinol. 2002 , 191 , 27 – 33 .
   PubMed Web of Science ®Google Scholar
• Kuiper , G.G.J.M. ; Enmark , E. ; Pelto-Huikko , M. ; Nilsson , S. ; Gustafsson , J.A. Cloning of a novel receptor expressed in rat prostate and ovary . Proc. Natl. Acad. Sci. USA 1996 , 93 , 5925 – 5930 .
   PubMed Web of Science ®Google Scholar
• Tremblay , G.B. ; Tremblay , A. ; Copeland , N.G. ; Gilbert , D.J. ; Jenkins , N.A. ; Lanitbodyrie , F. ; Giguere V. Cloning, chromosomal localization, and functional analysis of the murine estrogen receptor α . Molec. Endocrinol. 1997 , 11 , 353 – 365 .
   PubMed Web of Science ®Google Scholar
• Mosselman , S. ; Polman , J. ; Dijkema , R. ERα: identification and characterization of a novel human estrogen receptor . FEBS Lett. 1996 , 392 , 49 – 53 .
   PubMed Web of Science ®Google Scholar
• Scrimshaw , M.D. ; Lester , J.N. In-vitro assays for determination of oestrogenic activity . Anal. Bioanal. Chem. 2004 , 378 , 576 – 581 .
   PubMed Web of Science ®Google Scholar
• Kinnberg , K. Evaluation of in Vitro Assays for Determination of Estrogenic Activity in the Environment ; Danish Environmental Protecion Agency : Copenhagen , Denmark , 2003 .
   Google Scholar
• Körner , W. ; Hanf , V. ; Schuller , W. ; Bartsch , H. ; Zwirner , M. ; Hagenmaier , H. Validation and application of a rapid in vitro assay for assessing the estrogenic potency of halogenated phenolic chemicals . Chemosphere 1998 , 37 , 2395 – 2407 .
   PubMed Web of Science ®Google Scholar
• Navas , J.M. ; Segner , H. Vitellogenin synthesis in primary cultures of fish liver cells as endpoint for in vitro screening of the (anti)estrogenic activity of chemical substances . Aquatic Toxicol. 2006 , 80 , 1 – 22 .
   PubMed Web of Science ®Google Scholar
• Soule , H.D. ; Vazquez , J. ; Long , A. ; Albert , S. ; Brennan , M.A. A human cell line from a pleural effusion derived from a breast carcinoma . J Natl. Cancer Inst. 1973 , 57 , 1409 – 1412 .
   Google Scholar
• Brooks , S.C. ; Locke , E.R. ; Soule , H.D. Estrogen Receptor in a Human Cell Line (MCF-7) from Breast Carcinoma . J. Biol. Chem. 1973 , 248 , 6251 – 6253 .
   PubMed Web of Science ®Google Scholar
• Soto , A.M. ; Sonnenschein , C. ; Chung , K.L. ; Fernandez , M.F. The E-SCREEN assay as a tool to identify estrogens: An update on estrogenic environmental pollutants . Environ. Hlth. Perspect. 1995 , 103 , 113 – 122 .
   PubMed Web of Science ®Google Scholar
• Swart , N. ; Pool , E. Rapid Detection of Selected Steroid Hormones from Sewage Effluents using an ELISA in the Kuils River Water Catchment Area, South Africa. J. Immunoassay Immunochem. 2007, 28, 395–408.
   PubMed Web of Science ®Google Scholar
• Bradford , M. A rapid and sensitive method for the quantitaton of microgram quantities of protein utilizing the principle of protein-dye binding . Anal. Biochem. 1976 , 72 , 248 – 254 .
   PubMed Web of Science ®Google Scholar
• Maggiolini , M. ; Statti , G. ; Vivacqua , A. ; Ganitbodyriele , S. ; Rago , V. ; Loizzo , M. ; Menichini , F. ; Amdò , S. Estrogenic and antiproliferative activities of isoliquiritigenin in MCF7 breast cancer cells . J. Steroid Biochem. Molec. Biol. 2002 , 82 , 315 – 322 .
   PubMed Web of Science ®Google Scholar
• O Malley , B.W. ; Means , A.R. ; Socker , S.H. ; Spelsberg , T.C. ; Chytil , F. ; Comstock , J.P. ; Mitchell , W.M. Hormonal control of oviduct growth and differentiation . In: Macromolecules Regulating Growth and Development ; Hays , E.D. ; King , T.T. ; Papaconstantinou , J. ; Eds.; Academic Press. Inc. : New York , 1974 ; 53 – 77 .
   Google Scholar
• Inoue , A. ; Yoshida , N. ; Omoto , Y. ; Oguchi , S. ; Yamori , T. ; Kiyama , R. ; Hayashi , S. Development of cDNA microarray for expression profiling of estrogen-responsive genes . J. Molec. Endocrinol. 2002 , 29 , 175 – 192 .
   PubMed Web of Science ®Google Scholar
• Green , S. ; Chambon , P. The oestrogen receptor: from perception to mechanism . In: Nuclear hormone receptors, molecular mechanisms, cellular functions, clinical anitbodynormalities ; Parker , M.G. Ed; Academic Press : London , 1991 ; 15 – 38 .
   Google Scholar
• Morelli , C. Estrogen receptor α regulates the degradation of insulin receptor substrates 1 and 2 in breast cancer cells . Oncogene 2003 , 22 , 4007 – 4016 .
   PubMed Web of Science ®Google Scholar
• Likhite , V.S. Interaction of estrogen receptor α with 3-methyladenine DNA glycosylase modulates transcription and DNA repair . J. Biol. Chem. 2004 , 279 , 16875 – 16882 .
   PubMed Web of Science ®Google Scholar
• Villalobos , M. ; OIea , N. ; Antonio Brotons , J. ; Olea-Serrano , M.F. ; Ruiz de Almodovar , J.M. ; Pedraza , V. The E-Screen Assay: A Comparison of Different MCF7 Cell Stocks . Environ. Hlth. Perspect. 1995 , 103 , 844 – 850 .
   PubMed Web of Science ®Google Scholar
• Körner , W. ; Volker , H. ; Schuller , W. ; Kempterc , C. ; Metzgerc , J. ; Hagenmaiera , H. Development of a sensitive E-screen assay for quantitative analysis of estrogenic activity in municipal sewage plant effluents . Sci. Total Environ. 1999 , 225 , 33 – 48 .
   PubMed Web of Science ®Google Scholar
• Zacharewski , T. In vitro bioassays for assessing estrogenic substances . Environ. Sci. Technol. 1997 , 31 , 613 – 623 .
   Web of Science ®Google Scholar