419
Views
0
CrossRef citations to date
0
Altmetric
Residency Corner

Case Series: Synergistic Effect of Gabapentin and Adjuvant Pregabalin in Neuropathic Pain

Pages 106-109 | Received 17 Jun 2022, Accepted 10 Nov 2022, Published online: 13 Dec 2022

References

  • International Association for the Study of Pain. IASP Taxonomy. Pain Terms. Neuropathic Pain. Updated 2017 Dec 14. www.iasp-pain.org/Taxonomy#Neuropathicpain.
  • International Association for the Study of Pain. Epidemiology of Neuropathic Pain: How Common is Neuropathic Pain, and What Is Its Impact? Washington, DC: IASP; 2014. https://www.iasp-pain.org/Advocacy/Content.aspx?ItemNumber=3934
  • DiBonaventura M, Sadosky A, Concialdi K, Hopps M, Kudel I, Parsons B, Cappelleri JC, Hlavacek P, Alexander A, Stacey BR, et al. The prevalence of PROBABLE neuropathic pain in the US: results from a MULTIMODAL general-population health survey. JPR. 2017;10:2525–38. doi:10.2147/JPR.S127014
  • Bates D, Schultheis BC, Hanes MC, Jolly SM, Chakravarthy KV, Deer TR, Levy RM, Hunter CW. A comprehensive algorithm for management of neuropathic pain. Pain Med. 2019;20(Supplement_1):S2–S12. doi:10.1093/pm/pnz075
  • Griebeler ML, Morey-Vargas OL, Brito JP, Tsapas A, Wang Z, Carranza Leon BG, Phung OJ, Montori VM, Murad MH. Pharmacologic interventions for painful diabetic neuropathy. Ann Intern Med. 2014;161(9):639–49. doi:10.7326/M14-0511
  • Quilici S, Chancellor J, Löthgren M, Simon D, Said G, Le TK, Garcia-Cebrian A, Monz B. Meta-analysis of duloxetine vs. pregabalin and gabapentin in the treatment of diabetic peripheral neuropathic pain. BMC Neurol. 2009;9(1):6. doi:10.1186/1471-2377-9-6
  • Bockbrader HN, Wesche D, Miller R, Chapel S, Janiczek N, Burger P. A comparison of the pharmacokinetics and pharmacodynamics of pregabalin and gabapentin. Clin Pharmacokinet. 2010;49(10):661–9.
  • Yao Mak W, Siew Tan S. Pharmacokinetic comparison of two gabapentin formulations in healthy volunteers. J Bioequiv Bioavail. 2016;08(02):55–58.
  • Busch J, Strand J, Posvar E, et al. Pregabalin (CI-1008) multiple-dose pharmacokinetics and safety/tolerence in healthy volunteers [abstract]. Pharm Sci. 1999;1:2033.
  • Brummel RN, Singh L. A Synergistic Combination: Gabapentin and Pregabalin. Morris Plains, NJ. European Patent Specification. Publication number: EP1196160 B1. December 2005.
  • Senderovich H. Is there a role for combined use of gabapentin and pregabalin in pain control? Too good to be true? Curr Med Res Opin. 2018;34(4):677–82.
  • Solaro C, Messmer Uccelli M, Uccelli A, Leandri M, Mancardi GL. Low-dose gabapentin combined with either lamotrigine or carbamazepine can be useful therapies for trigeminal neuralgia in multiple sclerosis. Eur Neurol. 2000;44(1):45–8. doi:10.1159/000008192
  • Taheri A, Firouzi-Marani S, Masoud K, et al. A retrospective review of efficacy of combination therapy with pregabalin and carbamazepine versus pregabalin and amitriptyline in treatment of trigeminal neuralgia. Anaesth Pain & Intensive Care. 2015;19(1):8–12.
  • Serpell M, Latymer M, Almas M, Ortiz M, Parsons B, Prieto R. Neuropathic pain responds better to increased doses of pregabalin: an in-depth analysis of flexible-dose clinical trials. J Pain Res. 2017;10:1769–76. doi:10.2147/JPR.S129832

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.