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New Research: Assessment and Treatment

An Exposure-Based Cognitive–Behavioral Therapy for Youth with Severe Irritability: Feasibility and Preliminary Efficacy

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References

  • Abramowitz, J. S. (2013). The practice of exposure therapy: Relevance of cognitive-behavioral theory and extinction theory. Behavior Therapy, 44(4), 548–558. https://doi.org/10.1016/j.beth.2013.03.003
  • Althoff, R. R., Crehan, E. T., He, J. P., Burstein, M., Hudziak, J. J., & Merikangas, K. R. (2016). Disruptive mood dysregulation disorder at ages 13–18: Results from the national comorbidity survey—adolescent supplement. Journal of Child and Adolescent Psychopharmacology, 26(2), 107–113. https://doi.org/10.1089/cap.2015.0038
  • American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). https://doi.org/10.1176/appi.books.9780890425596
  • Awada, S. R., & Shelleby, E. C. (2021). Increases in maternal education and child behavioral and academic outcomes. Journal of Child & Family Studies, 30(7), 1813–1830. https://doi.org/10.1007/s10826-021-01983-7
  • Barkley, R. A. (2013). Defiant children: A clinician’s manual for assessment and parent training. Guilford Press.
  • Barlow, D. H., & Hersen, M. (1984). Single-case experimental designs: Strategies for studying behavior change (2nd ed.). Pergamon Press.
  • Barlow, D. H., Nock, M., & Hersen, M. (2009). Single case experimental designs: Strategies for studying behavior for change (3rd ed.). Pearson.
  • Benjamini, Y., & Hochberg, Y. (1995). Controlling the false discovery rate: A practical and powerful approach to multiple testing. Journal of the Royal Statistical Society: Series B (Statistical Methodology), 57(1), 289–300. https://doi.org/10.1111/j.2517-6161.1995.tb02031.x
  • Boldrini, T., Ghiandoni, V., Mancinelli, E., Salcuni, S., & Solmi, M. (2023). Systematic review and meta-analysis: Psychosocial treatments for disruptive behavior symptoms and disorders in adolescence. Journal of the American Academy of Child & Adolescent Psychiatry, 62(2), 169–189. https://doi.org/10.1016/j.jaac.2022.05.002
  • Brilleman, S. L., Howe, L. D., Wolfe, R., & Tilling, K. (2017). Bayesian piecewise linear mixed models with a random change point: An application to BMI rebound in childhood. Epidemiology, 28(6), 827–833. https://doi.org/10.1097/EDE.0000000000000723
  • Brotman, M. A., German, R. E., White, J., Gold, A. L., Kircanski, K., & Leibenluft, E. (2021). Exposure-based cognitive behavioral therapy for irritability and disruptive mood dysregulation disorder (DMDD) [ Unpublished manual]. Emotion and Development Branch, National Institute of Mental Health.
  • Brotman, M. A., Kircanski, K., Stringaris, A., Pine, D. S., & Leibenluft, E. (2017). Irritability in youths: A translational model. American Journal of Psychiatry, 174(6), 520–532. https://doi.org/10.1176/appi.ajp.2016.16070839
  • Brotman, M. A., Schmajuk, M., Rich, B. A., Dickstein, D. P., Guyer, A. E., Costello, E. J., Egger, H. L., Angold, A., Pine, D. S., & Leibenluft, E. (2006). Prevalence, clinical correlates, and longitudinal course of severe mood dysregulation in children. Biological Psychiatry, 60(9), 991–997. https://doi.org/10.1016/J.BIOPSYCH.2006.08.042
  • Burke, J. D., Boylan, K., Rowe, R., Duku, E., Stepp, S. D., Hipwell, A. E., & Waldman, I. D. (2014). Identifying the irritability dimension of ODD: Application of a modified bifactor model across five large community samples of children. Journal of Abnormal Psychology, 123(4), 841. https://doi.org/10.1037/a0037898
  • Burke, J. D., Pardini, D. A., & Loeber, R. (2008). Reciprocal relationships between parenting behavior and disruptive psychopathology from childhood through adolescence. Journal of Abnormal Child Psychology, 36(5), 679–692. https://doi.org/10.1007/s10802-008-9219-7
  • Busner, J., & Targum, S. D. (2007). Global impressions scale: Applying a research tool in clinical practice. Psychiatry (Edgmont), 4(7), 28–37.
  • Carpenter, A. L., Puliafico, A. C., Kurtz, S. M. S., Pincus, D. B., & Comer, J. S. (2014). Extending parent–child interaction therapy for early childhood internalizing problems: New advances for an overlooked population. Clinical Child and Family Psychology Review, 17(4), 340–356. https://doi.org/10.1007/s10567-014-0172-4
  • Carver, C. S., & Harmon-Jones, E. (2009). Anger is an approach-related affect: Evidence and implications. Psychological Bulletin, 135(2), 183–204. https://doi.org/10.1037/a0013965
  • Chambless, D. L., & Ollendick, T. H. (2001). Empirically supported psychological interventions: Controversies and evidence. Annual Review of Psychology, 52(1), 685–716. https://doi.org/10.1146/annurev.psych.52.1.685
  • Chorpita, B. F., & Daleiden, E. L. (2009). Mapping evidence-based treatments for children and adolescents: Application of the distillation and matching model to 615 treatments from 322 randomized trials. Journal of Consulting & Clinical Psychology, 77(3), 566–579. https://doi.org/10.1037/a0014565
  • Collishaw, S., Maughan, B., Natarajan, L., & Pickles, A. (2010). Trends in adolescent emotional problems in England: A comparison of two national cohorts twenty years apart. Journal of Child Psychology and Psychiatry and Allied Disciplines, 51(8), 885–894. https://doi.org/10.1111/j.1469-7610.2010.02252.x
  • Comer, J. S., Chow, C., Chan, P. T., Cooper-Vince, C., & Wilson, L. A. S. (2013). Psychosocial treatment efficacy for disruptive behavior problems in very young children: A meta-analytic examination. Journal of the American Academy of Child and Adolescent Psychiatry, 52(1), 26–36. https://doi.org/10.1016/j.jaac.2012.10.001
  • Copeland, W. E., Angold, A., Costello, J. E., & Egger, H. (2013). Prevalence, comorbidity, and correlates of DSM-5 proposed disruptive mood dysregulation disorder. American Journal of Psychiatry, 170(2), 173–179. https://doi.org/10.1176/appi.ajp.2012.12010132
  • Craske, M. G., Kircanski, K., Zelikowsky, M., Mystkowski, J., Chowdhury, N., & Baker, A. (2008). Optimizing inhibitory learning during exposure therapy. Behaviour Research and Therapy, 46(1), 5–27. https://doi.org/10.1016/j.brat.2007.10.003
  • Craske, M. G., Treanor, M., Conway, C. C., Zbozinek, T., & Vervliet, B. (2014). Maximizing exposure therapy: An inhibitory learning approach. Behaviour Research and Therapy, 58, 10–23. https://doi.org/10.1016/j.brat.2014.04.006
  • Dickstein, D. P., Towbin, K. E., Van Der Veen, J. W., Rich, B. A., Brotman, M. A., Knopf, L., Onelio, L., Pine, D. S., & Leibenluft, E. (2009). Randomized double-blind placebo-controlled trial of lithium in youths with severe mood dysregulation. Journal of Child and Adolescent Psychopharmacology, 19(1), 61–73. https://doi.org/10.1089/cap.2008.044
  • Dodge, K. A., Harnish, J. D., Lochman, J. E., Bates, J. E., & Pettit, G. S. (1997). Reactive and proactive aggression in school children and psychiatrically impaired chronically assaultive youth. Journal of Abnormal Psychology, 106(1), 37–51. https://doi.org/10.1037/0021-843X.106.1.37
  • Dougherty, L. R., Schwartz, K. T. G., Kryza-Lacombe, M., Weisberg, J., Spechler, P. A., & Lee Wiggins, J. (2018). Preschool- and school-age irritability predict reward-related brain function. Journal of the American Academy of Child and Adolescent Psychiatry, 57(6), 407–417.e2. https://doi.org/10.1016/j.jaac.2018.03.012
  • Dretzke, J., Davenport, C., Frew, E., Barlow, J., Stewart-Brown, S., Bayliss, S., Taylor, R. S., Sandercock, J., & Hyde, C. (2009). The clinical effectiveness of different parenting programmes for children with conduct problems: A systematic review of randomised controlled trials. Child and Adolescent Psychiatry and Mental Health, 3(1), 1–10. https://doi.org/10.1186/1753-2000-3-7
  • Ehrenreich-May, J., Kennedy, S. M., Sherman, J. A., Bilek, E. L., Buzzella, B. A., Bennett, S. M., & Barlow, D. H. (2017). Unified protocols for transdiagnostic treatment of emotional disorders in children and adolescents: Therapist guide. Oxford University Press.
  • Evans, S. C., Weisz, J. R., Carvalho, A. C., Garibaldi, P. M., Bearman, S. K., & Chorpita, B. F. (2020). Effects of standard and modular psychotherapies in the treatment of youth with severe irritability. Journal of Consulting and Clinical Psychology, 88(3), 255–268. https://doi.org/10.1037/ccp0000456
  • Ferron, J., & Sentovich, C. (2002). Statistical power of randomization tests used with multiple-baseline designs. The Journal of Experimental Education, 70(2), 165–178. https://doi.org/10.1080/00220970209599504
  • Furlong, M., McGilloway, S., Bywater, T., Hutchings, J., Smith, S. M., & Donnelly, M. (2012). Behavioural and cognitive‐behavioural group‐based parenting programmes for early‐onset conduct problems in children aged 3 to 12 years. Campbell Systematic Reviews, 8(1), 1–239. https://doi.org/10.4073/csr.2012.12
  • Ginsburg, G. S., Becker, E. M., Keeton, C. P., Sakolsky, D., Piacentini, J., Albano, A. M., Compton, S. N., Iyengar, S., Sullivan, K., Caporino, N., Peris, T., Birmaher, B., Rynn, M., March, J., & Kendall, P. C. (2014). Naturalistic follow-up of youths treated for pediatric anxiety disorders. JAMA Psychiatry, 71(3), 310–318. https://doi.org/10.1001/jamapsychiatry.2013.4186
  • Gliner, J. A., Morgan, G. A., & Harmon, R. J. (2000). Single-subject designs. Journal of the American Academy of Child and Adolescent Psychiatry, 39(10), 1327–1329. https://doi.org/10.1097/00004583-200010000-00023
  • Gonzalez, M. A., & Jones, D. J. (2016). Cascading effects of BPT for child internalizing problems and caregiver depression. Clinical Psychology Review, 50, 11–21. https://doi.org/10.1016/j.cpr.2016.09.007
  • Grodnitzky, G. R., & Tafrate, R. C. (2000). Imaginal exposure for anger reduction in adult outpatients: A pilot study. Journal of Behavior Therapy and Experimental Psychiatry, 31(3–4), 259–279. https://doi.org/10.1016/S0005-7916(01)00010-6
  • Grossman, R. A., & Ehrenreich-May, J. (2020). Using the unified protocol for transdiagnostic treatment of emotional disorders with youth exhibiting anger and irritability. Cognitive and Behavioral Practice, 27(2), 184–201. https://doi.org/10.1016/j.cbpra.2019.05.004
  • Guy, W. B. R. R. (1976). CGI. Clinical global impressions. ECDEU Assessment Manual for Psychopharmacology.
  • Haller, S. P., Kircanski, K., Stringaris, A., Clayton, M., Bui, H., Agorsor, C., Cardenas, S. I., Towbin, K. E., Pine, D. S., Leibenluft, E., & Brotman, M. A. (2020). The clinician affective reactivity index: Validity and reliability of a clinician-rated assessment of irritability. Behavior Therapy, 51(2), 283–293. https://doi.org/10.1016/j.beth.2019.10.005
  • Haller, S. P., Stoddard, J., Botz-Zapp, C., Clayton, M., MacGillivray, C., Perhamus, G., Stiles, K., Kircanski, K., Penton-Voak, I. S., Bar-Haim, Y., Munafò, M., Towbin, K. E., & Brotman, M. A. (2022). A randomized controlled trial of computerized interpretation bias training for disruptive mood dysregulation disorder: A fast-fail study. Journal of the American Academy of Child and Adolescent Psychiatry, 61(1), 37–45. https://doi.org/10.1016/j.jaac.2021.05.022
  • Hawks, J. L., Kennedy, S. M., Holzman, J. B. W., & Ehrenreich–May, J. (2020). Development and application of an innovative transdiagnostic treatment approach for pediatric irritability. Behavior Therapy, 51(2), 334–349. https://doi.org/10.1016/j.beth.2019.07.004
  • Herzhoff, K., & Tackett, J. L. (2016). Subfactors of oppositional defiant disorder: Converging evidence from structural and latent class analyses. Journal of Child Psychology and Psychiatry, 57(1), 18–29. https://doi.org/10.1111/jcpp.12423
  • Jacobson, N. S., & Truax, P. (1991). Clinical significance: A statistical approach to defining meaningful change in psychotherapy research. Journal of Consulting and Clinical Psychology, 59(1), 12–19. https://doi.org/10.1037/0022-006X.59.1.12
  • Jha, M. K., Minhajuddin, A., Chin Fatt, C., Kircanski, K., Stringaris, A., Leibenluft, E., & Trivedi, M. H. (2020). Association between irritability and suicidal ideation in three clinical trials of adults with major depressive disorder. Neuropsychopharmacology, 45(13), 2147–2154. https://doi.org/10.1038/s41386-020-0769-x
  • Kadouri, A., Corruble, E., & Falissard, B. (2007). The improved Clinical Global Impression Scale (iCGI): Development and validation in depression. BMC Psychiatry, 7(1), 1–7. https://doi.org/10.1186/1471-244X-7-7
  • Kaminski, J. W., & Claussen, A. H. (2017). Evidence base update for psychosocial treatments for disruptive behaviors in children. Journal of Clinical Child & Adolescent Psychology, 46(4), 477–499. https://doi.org/10.1080/15374416.2017.1310044
  • Kaufman, J., Birmaher, B., Brent, D., Rao, U., Flynn, C., Moreci, P., Williamson, D., & Ryan, N. (1997). Schedule for affective disorders and schizophrenia for school-age children-present and lifetime version (K-SADS-PL): Initial reliability and validity data. Journal of the American Academy of Child and Adolescent Psychiatry, 36(7), 980–988. https://doi.org/10.1097/00004583-199707000-00021
  • Kazdin, A. E. (1998). Psychosocial treatments for conduct disorder in children. In P. E. Nathan & J. M. Gorman (Eds.), A guide to treatments that work (pp. 65–89). Oxford University Press.
  • Kazdin, A. E. (2003). Research design in clinical psychology (4th ed.). London Pearson.
  • Kazdin, A. E. (2005). Child, parent, and family-based treatment of aggressive and antisocial child behavior. In E. D. Hibbs & P. S. Jensen (Eds.), Psychosocial treatments for child and adolescent disorders: Empirically based strategies for clinical practice (pp. 445–476). American Psychological Association.
  • Kazdin, A. E. (2010). Problem-solving skills training and parent management training for oppositional defiant disorder and conduct disorder. In J. R. Weisz & A. E. Kazdin (Eds.), Evidence-based psychotherapies for children and adolescents (2nd ed., pp. 159–178). Guilford Press.
  • Kazdin, A. E., Siegel, T. C., & Bass, D. (1992). Cognitive problem-solving skills training and parent management training in the treatment of antisocial behavior in children. Journal of Consulting and Clinical Psychology, 60(5), 733–747. https://doi.org/10.1037/0022-006x.60.5.733
  • Kircanski, K., Clayton, M. E., Leibenluft, E., & Brotman, M. A. (2018). Psychosocial treatment of irritability in youth. Current Treatment Options in Psychiatry, 5(1), 129–140. https://doi.org/10.1007/s40501-018-0141-5
  • Kircanski, K., Craske, M. G., Averbeck, B. B., Pine, D. S., Leibenluft, E., & Brotman, M. A. (2019). Exposure therapy for pediatric irritability: Theory and potential mechanisms. Behaviour Research and Therapy, 118, 141–149. https://doi.org/10.1016/j.brat.2019.04.007
  • Kjøbli, J., Melendez-Torres, G. J., Gardner, F., Backhaus, S., Linnerud, S., & Leijten, P. (2023). Research review: Effects of parenting programs for children’s conduct problems on children’s emotional problems - a network meta-analysis. Child Psychology and Psychiatry, 64(3), 348–356. https://doi.org/10.1111/jcpp.13697
  • Knackfuss, A. C. U., Leibenluft, E., Brotman, M. A., Moura, É. D., Júnior, S., Gerchmann, L., Fijtman, A., Trasel, A. R., Simioni, A., Teixeira, L. S., Sperotto, D., Manfro, A. G., Kapczinski, F., Anna, M. K. S., & Salum, G. A. (2020). Differentiating irritable mood and disruptive behavior in adults. Trends in Psychiatry and Psychotherapy, 42(4), 375–386. https://doi.org/10.1590/2237-6089-2019-0078
  • Kuny, A. V., Althoff, R. R., Copeland, W., Bartels, M., Van Beijsterveldt, C. E. M., Baer, J., & Hudziak, J. J. (2013). Separating the domains of oppositional behavior: Comparing latent models of the Conners’ oppositional subscale. Journal of the American Academy of Child & Adolescent Psychiatry, 52(2), 172–183. https://doi.org/10.1016/j.jaac.2012.10.005
  • Laporte, P. P., Matijasevich, A., Munhoz, T. N., Santos, I. S., Barros, A. J. D., Pine, D. S., Rohde, L. A., Leibenluft, E., & Salum, G. A. (2021). Disruptive mood dysregulation disorder: Symptomatic and syndromic thresholds and diagnostic operationalization. Journal of the American Academy of Child and Adolescent Psychiatry, 60(2), 286–295. https://doi.org/10.1016/j.jaac.2019.12.008
  • Lebowitz, E. R., Zilcha-Mano, S., Orbach, M., Shimshoni, Y., & Silverman, W. K. (2021). Moderators of response to child-based and parent-based child anxiety treatment: A machine learning-based analysis. Journal of Child Psychology & Psychiatry, 62(10), 1175–1182. https://doi.org/10.1111/jcpp.13386
  • Leibenluft, E., & Stoddard, J. (2013). The developmental psychopathology of irritability. Development and Psychopathology, 25(4 PART 2), 1473–1487. https://doi.org/10.1017/S0954579413000722
  • Lenhard, W., & Lenhard, A. (2016). Computation of effect sizes. Psychometrica. https://www.psychometrica.de/effect_size.html
  • Lochman, J. E., Burch, P. R., Curry, J. F., & Lampron, L. B. (1984). Treatment and generalization effects of cognitive-behavioral and goal-setting interventions with aggressive boys. Journal of Consulting and Clinical Psychology, 52(5), 915–916. https://doi.org/10.1037/0022-006X.52.5.915
  • Lochman, J. E., & Dodge, K. A. (1994). Social-cognitive processes of severely violent, moderately aggressive, and nonaggressive boys. Journal of Consulting and Clinical Psychology, 62(2), 366–374. https://doi.org/10.1037/0022-006X.62.2.366
  • Lochman, J. E., Powell, N. P., Boxmeyer, C. L., & Jimenez-Camargo, L. (2011). Cognitive-behavioral therapy for externalizing disorders in children and adolescents. Child and Adolescent Psychiatric Clinics of North America, 20(2), 305–318. https://doi.org/10.1016/j.chc.2011.01.005
  • Lösel, F., & Beelmann, A. (2003). Effects of child skills training in preventing antisocial behavior: A systematic review of randomized evaluations. The ANNALS of the American Academy of Political and Social Science, 587(1), 84–109. https://doi.org/10.1177/0002716202250793
  • McMahon, R. J., Wells, K. C., & Kotler, J. S. (2006). Conduct problems. In E. J. Mash & R. A. Barkley (Eds.), Treatment of childhood disorders (3rd ed., pp. 137–268). Guilford Press.
  • Michelson, D., Davenport, C., Dretzke, J., Barlow, J., & Day, C. (2013). Do evidence-based interventions work when tested in the “real world?” a systematic review and meta-analysis of parent management training for the treatment of child disruptive behavior. Clinical Child and Family Psychology Review, 16(1), 18–34. https://doi.org/10.1007/s10567-013-0128-0
  • Miller, L., Hlastala, S. A., Mufson, L., Leibenluft, E., Yenokyan, G., & Riddle, M. (2018). Interpersonal psychotherapy for mood and behavior dysregulation: Pilot randomized trial. Depression and Anxiety, 35(6), 574–582. https://doi.org/10.1002/da.22761
  • Morgan, D. L., & Morgan, R. K. (2001). Single-participant research design: Bringing science to managed care. American Psychologist, 56(2), 119–127. https://doi.org/10.1037/0003-066X.56.2.119
  • Naim, R., Kircanski, K., Gold, A., German, R. E., Davis, M., Perlstein, S., Clayton, M., Revzina, O., & Brotman, M. A. (2021). Across-subjects multiple baseline trial of exposure-based cognitive-behavioral therapy for severe irritability: A study protocol. British Medical Journal Open, 11(3), e039169. https://doi.org/10.1136/bmjopen-2020-039169
  • Naim, R., Smith, A., Chue, A., Grassie, H., Linke, J., Dombek, K., Shaughnessy, S., McNeil, C., Cardinale, E., Agorsor, C., Cardenas, S., Brooks, J., Subar, A. R., Jones, E. L., Do, Q. B., Pine, D. S., Leibenluft, E., Brotman, M. A., & Kircanski, K. (2021). Using ecological momentary assessment to enhance irritability phenotyping in a transdiagnostic sample of youth. Development and Psychopathology, 33(5), 1734–1746. https://doi.org/10.1017/S0954579421000717
  • Noelke, C., McArdle, N., Baek, M., Huntington, N., Huber, R., Hardy, E., & Acevedo-Garcia, D. (2020). Child opportunity index 2.0 technical documentation. https://diversitydatakids.org/researchlibrary/research-brief/how-we-built-it
  • Ollendick, T. H. (1995). Cognitive behavioral treatment of panic disorder with agoraphobia in adolescents: A multiple baseline design analysis. Behavior Therapy, 26(3), 517–531. https://doi.org/10.1016/S0005-7894(05)80098-X
  • Onghena, P., & Edgington, E. S. (2005). Customization of pain treatments: Single-case design and analysis. The Clinical Journal of Pain, 21(1), 56–68. https://doi.org/10.1097/00002508-200501000-00007
  • Orri, M., Galera, C., Turecki, G., Boivin, M., Tremblay, R. E., Geoffroy, M. C., & Côté, S. M. (2019). Pathways of association between childhood irritability and adolescent suicidality. Journal of the American Academy of Child and Adolescent Psychiatry, 58(1), 99–107.e3. https://doi.org/10.1016/j.jaac.2018.06.034
  • Orri, M., Perret, L. C., Turecki, G., & Geoffroy, M. C. (2018). Association between irritability and suicide-related outcomes across the life-course. Systematic review of both community and clinical studies. Journal of Affective Disorders, 239, 220–233. https://doi.org/10.1016/j.jad.2018.07.010
  • Patterson, G. R. (1982). Coercive family process. Castalia Pub Co.
  • Perepletchikova, F., Nathanson, D., Axelrod, S. R., Merrill, C., Walker, A., Grossman, M., Rebeta, J., Scahill, L., Kaufman, J., Flye, B., Mauer, E., & Walkup, J. (2017). Randomized clinical trial of dialectical behavior therapy for preadolescent children with disruptive mood dysregulation disorder: Feasibility and outcomes. Journal of the American Academy of Child and Adolescent Psychiatry, 56(10), 832–840. https://doi.org/10.1016/j.jaac.2017.07.789
  • Peterson, B. S., Zhang, H., Santa Lucia, R., King, R. A., & Lewis, M. (1996). Risk factors for presenting problems in child psychiatric emergencies. Journal of the American Academy of Child and Adolescent Psychiatry, 35(9), 1162–1173. https://doi.org/10.1097/00004583-199609000-00014
  • Pickles, A., Aglan, A., Collishaw, S., Messer, J., Rutter, M., & Maughan, B. (2010). Predictors of suicidality across the life span: The isle of wight study. Psychological Medicine, 40(9), 1453–1466. https://doi.org/10.1017/S0033291709991905
  • Pilling, S., Gould, N., Whittington, C., Taylor, C., & Scott, S. (2013). Recognition, intervention, and management of antisocial behaviour and conduct disorders in children and young people: Summary of NICE-SCIE guidance. BMJ (Online), 346(7902), 1–4. https://doi.org/10.1136/bmj.f1298
  • Raudenbush, S. W., & Congdon, R. T. (2021). HLM 8: Hierarchical linear and nonlinear modeling. Scientific Software International, Inc.
  • Rothenberg, W. A., Lansford, J. E., Al-Hassan, S. M., Bacchini, D., Bornstein, M. H., Chang, L., Deater-Deckard, K., DiGiunta, L., Dodge, K. A., Malone, P. S., Oburu, P., Pastorelli, C., Skinner, A. T., Sorbring, E., Steinberg, L., Tapanya, S., Maria Uribe Tirado, L., Yotanyamaneewong, S., & Peña Alampay, L. (2020). Examining effects of parent warmth and control on internalizing behavior clusters from age 8 to 12 in 12 cultural groups in nine countries. Journal of Child Psychology and Psychiatry and Allied Disciplines, 61(4), 436–446. https://doi.org/10.1111/jcpp.13138
  • Scahill, L., McDougle, C. J., Aman, M. G., Johnson, C., Handen, B., Bearss, K., Dziura, J., Butter, E., Swiezy, N. G., Arnold, L. E., Stigler, K. A., Sukhodolsky, D. D., Lecavalier, L., Pozdol, S. L., Nikolov, R., Hollway, J. A., Korzekwa, P., Gavaletz, A., Kohn, A. E., … Vitiello, B. (2012). Effects of risperidone and parent training on adaptive functioning in children with pervasive developmental disorders and serious behavioral problems. Journal of the American Academy of Child and Adolescent Psychiatry, 51(2), 136–146. https://doi.org/10.1016/j.jaac.2011.11.010
  • Scott, S., Briskman, J., & O’Connor, T. G. (2014). Early prevention of antisocial personality: Long-term follow-up of two randomized controlled trials comparing indicated and selective approaches. American Journal of Psychiatry, 171(6), 649–657. https://doi.org/10.1176/appi.ajp.2014.13050697
  • Silverman, W. K., Marin, C. E., Rey, Y., Kurtines, W. M., Jaccard, J., & Pettit, J. W. (2019). Group-versus parent-involvement CBT for childhood anxiety disorders: Treatment specificity and long-term recovery mediation. Clinical Psychological Science, 7(4), 840–855. https://doi.org/10.1177/2167702619830404
  • Snijders, T. A. B., & Bosker, R. J. (2012). Multilevel analysis: An introduction to basic and advanced multilevel modeling (2nd ed.). Sage.
  • Stoddard, J., Sharif-Askary, B., Harkins, E. A., Frank, H. R., Brotman, M. A., Penton-Voak, I. S., Maoz, K., Bar-Haim, Y., Munafo, M., Pine, D. S., & Leibenluft, E. (2016). An open pilot study of training hostile interpretation bias to treat disruptive mood dysregulation disorder. Journal of Child and Adolescent Psychopharmacology, 26(1), 49–57. https://doi.org/10.1089/cap.2015.0100
  • Stoddard, J., Stringaris, A., Brotman, M. A., Montville, D., Pine, D. S., & Leibenluft, E. (2014). Irritability in child and adolescent anxiety disorders. Depression and Anxiety, 31(7), 566–573. https://doi.org/10.1002/da.22151
  • Stringaris, A., Cohen, P., Pine, D. S., & Leibenluft, E. (2009). Adult outcomes of youth irritability: A 20-year prospective community-based study. American Journal of Psychiatry, 166(9), 1048–1054. https://doi.org/10.1176/appi.ajp.2009.08121849
  • Stringaris, A., & Goodman, R. (2009). Three dimensions of oppositionality in youth. Journal of Child Psychology and Psychiatry, 50(3), 216–223. https://doi.org/10.1111/j.1469-7610.2008.01989.x
  • Stringaris, A., Goodman, R., Ferdinando, S., Razdan, V., Muhrer, E., Leibenluft, E., & Brotman, M. A. (2012). The affective reactivity index: A concise irritability scale for clinical and research settings. Journal of Child Psychology and Psychiatry and Allied Disciplines, 53(11), 1109–1117. https://doi.org/10.1111/j.1469-7610.2012.02561.x
  • Stringaris, A., Vidal-Ribas, P., Brotman, M. A., & Leibenluft, E. (2018). Practitioner review: Definition, recognition, and treatment challenges of irritability in young people. Journal of Child Psychology and Psychiatry and Allied Disciplines, 59(7), 721–739. https://doi.org/10.1111/jcpp.12823
  • Sukhodolsky, D. G., Kassinove, H., & Gorman, B. S. (2004). Cognitive-behavioral therapy for anger in children and adolescents: A meta-analysis. Aggression and Violent Behavior, 9(3), 247–269. https://doi.org/10.1016/j.avb.2003.08.005
  • Sukhodolsky, D. G., & Scahill, L. (2012). Cognitive-behavioral therapy for anger and aggression in children. Guilford Press.
  • Sukhodolsky, D. G., Smith, S. D., McCauley, S. A., Ibrahim, K., & Piasecka, J. B. (2016). Behavioral interventions for anger, irritability, and aggression in children and adolescents. Journal of Child and Adolescent Psychopharmacology, 26(1), 58–64. https://doi.org/10.1089/cap.2015.0120
  • Tarpley, J. W., Shlifer, I. G., Halladay, L. R., & Blair, H. T. (2010). Conditioned turning behavior: A Pavlovian fear response expressed during the post-encounter period following aversive stimulation. Neuroscience, 169(4), 1689–1704. https://doi.org/10.1016/j.neuroscience.2010.06.046
  • Towbin, K., Vidal-Ribas, P., Brotman, M. A., Pickles, A., Miller, K. V., Kaiser, A., Vitale, A. D., Engel, C., Overman, G. P., Davis, M., Lee, B., McNeil, C., Wheeler, W., Yokum, C. H., Haring, C. T., Roule, A., Wambach, C. G., Sharif-Askary, B., Pine, D. S., … Stringaris, A. (2020). A double-blind randomized placebo-controlled trial of citalopram adjunctive to stimulant medication in youth with chronic severe irritability. Journal of the American Academy of Child and Adolescent Psychiatry, 59(3), 350–361. https://doi.org/10.1016/j.jaac.2019.05.015
  • Vidal-Ribas, P., Brotman, M. A., Valdivieso, I., Leibenluft, E., & Stringaris, A. (2016). The status of irritability in psychiatry: A conceptual and quantitative review. Journal of the American Academy of Child and Adolescent Psychiatry, 55(7), 556–570. https://doi.org/10.1016/j.jaac.2016.04.014
  • Ward, M. A., Theule, J., & Cheung, K. (2016). Parent–child interaction therapy for child disruptive behaviour disorders: A meta-analysis. Child & Youth Care Forum, 45(5), 675–690. https://doi.org/10.1007/s10566-016-9350-5
  • Waxmonsky, J. G., Waschbusch, D. A., Belin, P., Li, T., Babocsai, L., Humphery, H., Pariseau, M. E., Babinski, D. E., Hoffman, M. T., Haak, J. L., Mazzant, J. R., Fabiano, G. A., Pettit, J. W., Fallahazad, N., & Pelham, W. E. (2016). A randomized clinical trial of an integrative group therapy for children with severe mood dysregulation. Journal of the American Academy of Child and Adolescent Psychiatry, 55(3), 196–207. https://doi.org/10.1016/j.jaac.2015.12.011
  • Webster-Stratton, C., & Herman, K. C. (2008). The impact of parent behavior-management training on child depressive symptoms. Journal of Consulting Psychology, 55(4), 473–484. https://doi.org/10.1037/a0013664. PMID: 22017554
  • Wechsler, D. (1999). Manual for the Wechsler abbreviated intelligence scale (WASI). The Psychological Corporation.
  • Weisz, J. R., Kuppens, S., Ng, M. Y., Eckshtain, D., Ugueto, A. M., Vaughn-Coaxum, R., Jensen-Doss, A., Hawley, K. M., Krumholz Marchette, L. S., Chu, B. C., Weersing, V. R., & Fordwood, S. R. (2017). What five decades of research tells us about the effects of youth psychological therapy: A multilevel meta-analysis and implications for science and practice. American Psychologist, 72(2), 79–117. https://doi.org/10.1037/a0040360
  • Wiggins, J. L., Brotman, M. A., Adleman, N. E., Kim, P., Oakes, A. H., Reynolds, R. C., Chen, G., Pine, D. S., & Leibenluft, E. (2016). Neural correlates of irritability in disruptive mood dysregulation and bipolar disorders. American Journal of Psychiatry, 173(7), 722–730. https://doi.org/10.1176/appi.ajp.2015.15060833
  • Zachary, C., Jones, D. J., McKee, L. G., Baucom, D. H., & Forehand, R. L. (2019). The role of emotion regulation and socialization in behavioral parent training: A proof-of-concept study. Behavior Modification, 43(1), 3–25. https://doi.org/10.1177/0145445517735492
  • Zisser-Nathenson, A. R., Herschell, A. D., & Eyberg, S. M. (2018). Parent-child interaction therapy and the treatment of disruptive behavior disorders. In J. R. Weisz & A. E. Kazdin (Eds.), Evidence-based psychotherapies for children and adolescents (pp. 103–121). The Guilford Press.