Role of inflammatory cytokines and DNA damage repair proteins in sulfur mustard exposed mice liver

References

• Anderson MT, Stall FJ, Gitler C, Herzenberg LA. 1990. Separation of oxidant-initiated and redox-regulated steps in the NFκB signal transduction. Proc Natl Acad Sci USA 24:11527–11531.
   Google Scholar
• Aziz Q, Marian N, Juanita G, Charlene C, Bor-Jang H, Mark S. 2005. Modulation of sulfur mustard induced cell death in human epidermal keratinocytes using IL-10 and TNF-α. J Biochem Mol Toxicol 19:213–225.
   Google Scholar
• Baeuerle PA, Henkel T. 1994. Function and activation of NF-κB in the immune system. Annu Rev Immunol 12:141–179.
   PubMed Web of Science ®Google Scholar
• Bhattacharya R, Rao PVL, Pant SC, Kumar P, Tulsawani RK, Pathak U, Kulkarni A, Vijayaraghavan R. 2001. Protective effects of amifostine and its analogues on sulfur mustard toxicity in vitro and in vivo. Toxicol Appl Pharmacol 176:24–33.
   PubMed Web of Science ®Google Scholar
• Chew AL, Bennet A, Smith CH, Barker J, Kirkham B. 2004. Successful treatment of severe psoriasis and psoriatic arthritis with adalimumab. Br J Dermatol 151:492–496.
   PubMed Web of Science ®Google Scholar
• Christman JW, Sadikot RT, Blackwell TS. 2000. The role of nuclear factor-kappa B in pulmonary diseases. Chest 117:1482–1487.
   PubMed Web of Science ®Google Scholar
• Clarke HT. 1912. Synthesis of 4-alkyl-1,4-thiazans. J Chem Soc 101:1583–1590.
   Google Scholar
• Cox MM, Goodman MF, Kreuzer KN, Sherratt DJ, Sandler SJ, Marians KJ. 2000. The importance of repairing stalled replication forks. Nature 404:37–41.
   PubMed Web of Science ®Google Scholar
• Dacre JC, Goldman M. 1996. Toxicology and pharmacology of the chemical warfare agent sulfur mustard. Pharmacol Rev 48:289–326.
   PubMed Web of Science ®Google Scholar
• Dillman JF, Phillips CS, Dorsch LM, Croxton MD, Hege AI, Sylvester AJ, Moran TS, Sciuto AM. 2005. Genomic analysis of rodent pulmonary tissue following Bis-(2-chloroethyl) sulfide exposure. Chem Res Toxicol 18:28–34.
   PubMed Web of Science ®Google Scholar
• Essers J, Hendriks RW, Swagemakers SMA, Troelstra C, de Wit JD, Bootsma D, Hoeijmakers JMJ, Kanaar R. 1997. Disruption of mouse RAD54 reduces ionizing radiation resistance and homologous recombination. Cell 89:195–204.
   PubMed Web of Science ®Google Scholar
• Fernandez-Capetillo O, Lee A, Nussenzweig M, Nussenzweig A. 2004. H2AX: the histone guardian of the genome. DNA Repair 3:959–967.
   PubMed Web of Science ®Google Scholar
• Goldberg M, Stucki M, Falck J, D’Amours D, Rahman D, Pappin D, Bartek J, Jackson SP. 2003. MDC1 is required for the intra-S-phase DNA damage checkpoint. Nature 421:952–956.
   PubMed Web of Science ®Google Scholar
• Hutter D, Green JJ. 2000. Influence of the cellular redox state on NF-κB-regulated gene expression. J Cell Physiol 183:45–52.
   PubMed Web of Science ®Google Scholar
• Mocellin S, Marincola F, Rossi CR, Nitti D, Lise M. 2004. The multifaceted relationship between IL-10 and adaptive immunity: putting together the pieces of a puzzle. Cytokine Growth Factor Rev 15:61–76.
   PubMed Web of Science ®Google Scholar
• Monteiro-Riviere NA, Inman AO, Babin MC, Casillas RP. 1999. Immuno histochemical characterization of the basement membrane epitopes in bis(2-chloroethyl) sulfide-induced toxicity in mouse ear skin. J Appl Toxicol 19:313–328.
   PubMed Web of Science ®Google Scholar
• Morales M, Jan-Willem FT, Kim CFB, Kitagawa R, Kastan MB, Petrini JHJ. 2005. The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor. Genes Dev 19:3043–3054.
   PubMedGoogle Scholar
• Paull TT, Rogakou EP, Yamazaki V, Kirchgessner CU, Gellert M, Bonner WM. 2000. A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr Biol 10:886–895.
   PubMed Web of Science ®Google Scholar
• Rao PVL, Vijayaraghavan R, Bhaskar ASB. 1999. Sulfur mustard induced DNA damage in mice after dermal and inhalation exposure. Toxicology 139:39–51.
   Google Scholar
• Rogakou EP, Boon C, Redon C, Bonner WM. 1999. Megabase chromatin domains involved in DNA double-strand breaks in vivo. J Cell Biol 146:905–916.
   PubMed Web of Science ®Google Scholar
• Rogers JV, Young WC, Robyn CK, Michael CB, Robert PC, John JS, Carol LKS. 2005. Microarray analysis of gene expression in murine skin exposed to sulfur mustard. J Biochem Mol Toxicol 18:289–299.
   Google Scholar
• Rosenthal DS, Simbulan-Rosenthal CM, Iyer S, Smith WJ, Ray R, Smulson ME. 2000. Calmodulin, poly(ADP ribose) polymerase and p53 are targets for modulating the effects of sulfur mustard. J Appl Toxicol 20:S43–S49.
   PubMedGoogle Scholar
• Rosenthal DS, Simbulan-Rosenthal CM, Iyer S, Spoonde A, Smith W, Ray R, Smulson E. 1998. Sulfur mustard induces markers of terminal differentiation and apoptosis in keratinocytes via a Ca2+-calmodulin and caspase-dependent pathway. J Invest Dermatol 111:64–71.
   PubMed Web of Science ®Google Scholar
• Sabourin CLK, Petrali JP, Casillas RP. 2000. Alterations in inflammatory cytokine gene expression in sulfur mustard-exposed mouse skin. J Biochem Mol Toxicol 14:291–301.
   PubMed Web of Science ®Google Scholar
• Schwartzman S, Fleischermann R, Morgan GJ. 2004. Do anti-TNF agents have equal efficacy in patients with rheumatoid arthritis? Arthritis Res Ther 6:S3–S11.
   Google Scholar
• Sen KC. 2000. Cellular thiols and redox-regulated signal transduction. Curr Top Cell Regul 36:1–30.
   PubMedGoogle Scholar
• Sidell FR, Urbanetti JS, Smith WJ, Hurst CG. 1997. Vesicants. In: Sidell FR, Takafuji ET, Franz DR (Eds.), Textbook of military medicine, warfare, weaponry, and the casualty. Medical aspects of chemical and biological warfare, TMM Publications, Washington, DC, pp. 197–228.
   Google Scholar
• Smith KJ, Graham JS, Hamilton TA, Skelton HG, Petrali JP, Hurst CG. 1997. Immunohistochemical studies of basement membrane proteins and proliferation and apoptosis markers in sulfur mustard induced cutaneous lesions in weanling pigs. J Dermatol Sci 15:173–182.
   PubMed Web of Science ®Google Scholar
• Sreenivasan Y, Sarkar A, Manna SK. 2003. Mechanism of cytosine arabinoside-mediated apoptosis: role of Rel A (p65) dephosphorylation. Oncogene 22:4356–4369.
   Google Scholar
• Stern R, Wolf F. 2004. Infliximab dose and clinical status: results of 2 studies in 1642 patients with rheumatoid arthritis. J Rheumatol 31:1538–1545.
   PubMed Web of Science ®Google Scholar
• Strom L, Lindroos HB, Shirahige K, Sjogren C. 2004. Post replicative recruitment of cohesin to double-strand breaks is required for DNA repair. Mol Cell 16:1003–1015.
   PubMed Web of Science ®Google Scholar
• Tan TL, Kannar R, Wyman C. 2003. Rad 54, A Jack of all trades in homologous recombination. DNA Repair. 2: 787–794.
   PubMed Web of Science ®Google Scholar
• Thiriet C, Hayes JJ. 2005. Chromatin in need of a fix: phosphorylation of H2AX connects chromatin to DNA repair. Mol Cell 18:617–622.
   PubMed Web of Science ®Google Scholar
• Unal E, Arbel-Eden A, Sattler U, Shroff R, Lichten M, Haber JE, Koshland D. 2004. DNA damage response pathway uses histone modification to assemble a double-strand break specific cohesin domain. Mol Cell 16:991–1002.
   PubMed Web of Science ®Google Scholar
• Van Dyck E, Stasiak AZ, West SC. 1999. Binding of double-strand breaks in DNA by human Rad52 protein. Nature 398:728–731.
   Google Scholar
• Vijayaraghavan R, Kulkarni A, Pant SC, Kumar P, Rao PVL, Gupta N, Gautam A, Ganesan K. 2005. Differential toxicity of sulfur mustard administered through percutaneous, subcutaneous and oral routes. Toxicol Appl Pharmacol 202:180–188.
   PubMed Web of Science ®Google Scholar
• Watkins SK, Egilmez NK, Suttles J, Stout RD. 2007. IL-12 rapidly alters the functional profile of tumor-associated and tumor infiltrating macrophages in vitro and in vivo. J Immunol 178:1357–1362.
   PubMed Web of Science ®Google Scholar
• Whalen JD, Lechman EL, Carlos CA, Weiss K, Kovesdi I, Glorioso JC, Robins PD, Evans CH. 1999. Adenoviral transfer of the viral IL-10 gene peri-articularly to mouse paws suppresses development of Collagen-induced arthritis in both injected and uninjected paws. J Immunol 162:3625–3632.
   PubMed Web of Science ®Google Scholar
• Xie A, Puget N, Shim I, Odate S, Jarzyna I, Bassing CH, Alt FW, Scully R. 2004. Control of sister chromatid recombination by histone H2AX. Mol Cell 16:1017–1025.
   PubMed Web of Science ®Google Scholar
• Yanez RJ, Porter ACG. 1999. Gene targeting is enhanced in human cells over expressing hRAD51. Gene Ther 6:1282–1290.
   PubMedGoogle Scholar
• Yao Y, Li W, Kaplan MH, Chang CH. 2005. Interleukin (IL)-4 inhibit IL-10 to promote IL-12 production by dendritic cells. J Expt Med 201:1899–1903.
   PubMed Web of Science ®Google Scholar
• Zhang Z, Peters BP, Monteiro-Riviere NA. 1995. Assessment of sulfur mustard interaction with basement membrane components. Cell Biol Toxicol 11:89–101.
   PubMed Web of Science ®Google Scholar