References
- Bajgar J. 2004. Organophosphate/nerve agent poisoning: mechanism of action, diagnosis, prophylaxis, and treatment. Adv Clin Chem 38:151–216.
- Clement JG, Hansen AS, Boulet CA. 1992. Efficacy of HLö-7 and pyrimidoxime as antidotes of nerve agent poisoning in mice. Arch Toxicol 66:216–219.
- Dawson RM. 1994. Review of oximes available for treatment of nerve agent poisoning. J Appl Toxicol 14:317–331.
- Ellman GL, Courtney DK, Andres V Jr, Featherstone RM. 1961. A new and rapid determination of acetylcholinesterase activity. Biochem Pharmacol 7:88–93.
- Kassa J. 2002. Review of oximes in the antidotal treatment of poisoning by organophosphorus nerve agents. J Toxicol Clin Toxicol 40:803–816.
- Kassa J, Cabal J. 1999a. A comparison of the efficacy of a new asymmetric bispyridinium oxime BI-6 with currently available oximes and H oximes against soman by in vitro and in vivo methods. Toxicology 132:111–118.
- Kassa J, Cabal J. 1999b. A comparison of the efficacy of acetylcholinesterase reactivators against cyclohexyl methylphosphonofluoridate (GF agent) by in vitro and in vivo methods. Pharmacol Toxicol 84:41–45.
- Kassa J, Cabal J. 1999c. A comparison of the efficacy of a new asymmetric bispyridinium oxime BI-6 with presently used oximes and H oximes against sarin by in vitro and in vivo methods. Hum Exp Toxicol 18:560–565.
- Kassa J, Karasova J, Musilek K, Kuca K. 2008. An evaluation of therapeutic and reactivating effects of newly developed oximes (K156, K203) and commonly used oximes (obidoxime, trimedoxime, HI-6) in tabun-poisoned rats and mice. Toxicology 243:311–316.
- Kassa J, Kuca K, Bartosova L, Kunesova G. 2007. The development of new structural analogues of oximes for the antidotal treatment of poisoning by nerve agents and the comparison of their reactivating and therapeutic efficacy with currently available oximes. Curr Org Chem 11:267–283.
- Kuca K, Cabal J, Jun D, Kassa J, Bartosova L, Kunesova G. 2005. In vitro reactivation potency of some acetylcholinesterase reactivators against sarin- and cyclosarin-induced inhibitions. J Appl Toxicol 25:296–300.
- Kuca K, Cabal J, Kassa J. 2004. A comparison of the efficacy of a bispyridinium oxime—1,4-bis-(2-hydroxyiminomethylpyridinium) butane dibromide and currently used oximes to reactivate sarin, tabun or cyclosarin-inhibited acetylcholinesterase by in vitro methods. Pharmazie 59:795–798.
- Kuca K, Jun D, Bajgar J. 2007a. Currently used cholinesterase reactivators against nerve agent intoxication: comparison of their effectivity in vitro. Drug Chem Toxicol 30:31–40.
- Kuca K, Jun D, Musilek K. 2006. Structural requirements of acetylcholinesterase reactivators. Mini Rev Med Chem 6:269–277.
- Kuca K, Musilek K, Paar M, Jun D, Stodulka P, Hrabinova M, Marek J. 2007b. Targeted synthesis of 1-(4-hydroxyiminomethylpyridinium)-3-pyridinium propane dibromide—a new nerve agent reactivator. Molecules 12:1964–1972.
- Kuca J, Patocka J. 2004. Reactivation of cyclosarin-inhibited rat brain acetylcholinesterase by pyridinium-oximes. J Enz Inhib Med Chem 19:39–43.
- Kuca K, Racakova V, Jun D, Bajgar J. 2007c. Structure-activity relationship of acetylcholinesterase reactivators—antidotes against nerve agents. Lett Org Chem 4:212–217.
- Lotti M. 2000. Organophosphorus compounds. In: Spencer PS, Schaumburg HH (Eds.), Experimental and clinical neurotoxicology. New York: Oxford University Press; pp. 898–925.
- Marrs TC. 1993. Organophosphate poisoning. Pharmacol Ther 58:51–66.
- Musilek K, Holas O, Kuca K, Jun D, Dohnal V, Opletalova V, Dolezal M. 2008. Synthesis of monooxime-monocarbamoyl bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against tabun- and paraoxon-inhibited acetylcholinesterase. J Enz Inhib Med Chem 23:70–76.
- Shih TM. 1993. Comparison of several oximes on reactivation of soman-inhibited blood, brain and tissue cholinesterase activity. Arch Toxicol 67:637–646.
- Tallarida R, Murray R. 1987. Manual of pharmacological calculation with computer programs. New York: Springer-Verlag.
- Taylor P. 2001. Anticholinesterase agents. In: Hardman JG, Limbird LE. (Eds.), The pharmacological basis of therapeutics. New York: McGraw Hill; pp. 175–191.
- Worek F, Widmann R, Knopff O, Szinicz L. 1998. Reactivating potency of obidoxime, pralidoxime, HI-6 and HLö-7 in human erythrocyte acetylcholinesterase inhibited by highly toxic organophosphorus compounds. Arch Toxicol 72:237–243.