Effects of timolol on Ca²⁺ handling and viability in human prostate cancer cells

References

• Ayaki M, Yaguchi S, Iwasawa A, Koide R, et al. 2008. Cytotoxicity of ophthalmic solutions with and without preservatives to human corneal endothelial cells, epithelial cells and conjunctival epithelial cells. Clin Experiment Ophthalmol. 36:553–559.
   PubMed Web of Science ®Google Scholar
• Beekharry CC, Gu Y, Magoski NS. 2018. Protein kinase C enhances electrical synaptic transmission by acting on junctional and postsynaptic Ca2+ currents. J Neurosci. 38:2796–2808.
   PubMed Web of Science ®Google Scholar
• Berridge MJ. 1997. Elementary and global aspects of calcium signaling. J Physiol. 499:291–306.
   PubMed Web of Science ®Google Scholar
• Berridge MJ. 2006. Calcium microdomains: organization and function. Cell Calcium. 40:405–412.
   PubMed Web of Science ®Google Scholar
• Chen I-S, Chou C-T, Liu Y-Y, Yu C-C, Liang W-Z, Kuo C-C, Shieh P, Kuo D-H, Chen F-A, Jan C-R, et al. 2017. The investigation of minoxidil-induced [Ca2+]i rises and non-Ca2+-triggered cell death in PC3 human prostate cancer cells. J Recept Signal Transduct Res. 37:1–7.
   PubMed Web of Science ®Google Scholar
• Chen Y-N, Yamada H, Mao W, Matsuyama S, Aihara M, Araie M. 2007. Hypoxia-induced retinal ganglion cell death and the neuroprotective effects of beta-adrenergic antagonists. Brain Res. 1148:28–37.
   PubMed Web of Science ®Google Scholar
• Cheng J-W, Cheng S-W, Gao L-D, Lu G-C, Wei R-L. 2012. Intraocular pressure-lowering effects of commonly used fixed-combination drugs with timolol: a systematic review and meta-analysis. PLoS One. 7:e45079.
   PubMed Web of Science ®Google Scholar
• Cheong HI, Johnson J, Cormier M, Hosseini K. 2008. In vitro cytotoxicity of eight beta-blockers in human corneal epithelial and retinal pigment epithelial cell lines: comparison with epidermal keratinocytes and dermal fibroblasts. Toxicol In Vitro. 22:1070–1076.
   PubMed Web of Science ®Google Scholar
• Dong Y, Ishikawa H, Wu Y, Shimizu K, Goseki T, Yoshitomi T. 2006. Effect and mechanism of betaxolol and timolol on vascular relaxation in isolated rabbit ciliary artery. Jpn J Ophthalmol. 50:504–508.
   PubMed Web of Science ®Google Scholar
• Florenzano F, Viscomi MT, Mercaldo V, Longone P, Bernardi G, Bagni C, Molinari M, Carrive P. 2006. P2X2R purinergic receptor subunit mRNA and protein are expressed by all hypothalamic hypocretin/orexin neurons. J Comp Neurol. 498:58–67.
   PubMed Web of Science ®Google Scholar
• Grynkiewicz G, Poenie M, Tsien RY. 1985. A new generation of Ca2+ indicators with greatly improved fluorescence properties. J Biol Chem. 260:3440–3450.
   PubMed Web of Science ®Google Scholar
• Harisseh R, Chatelier A, Magaud C, Déliot N, Constantin B. 2013. Involvement of TRPV2 and SOCE in calcium influx disorder in DMD primary human myotubes with a specific contribution of α1-syntrophin and PLC/PKC in SOCE regulation. Am J Physiol Cell Physiol. 304:C881–C894.
   PubMed Web of Science ®Google Scholar
• Hong S-J, Wu K-Y, Wang H-Z, Fong JC. 2003. Effects of commercial antiglaucoma drugs to glutamate-induced [Ca2+]i increase in cultured neuroblastoma cells. J Ocul Pharmacol Ther. 19:205–215.
   PubMed Web of Science ®Google Scholar
• Horng C-T, Chou C-T, Sun T-K, Liang W-Z, Kuo C-C, Wang J-L, Shieh P, Jan C-R. 2017. Effect of carvacrol on Ca2+ movement and viability in PC3 human prostate cancer cells. Chin J Physiol. 60:275–283.
   PubMed Web of Science ®Google Scholar
• Lecanu L, Margaill I, Boughali H, Cohen-Tenoudji B, Boulu RG, Plotkine M. 1998. Deleterious Ca-independent NOS activity after oxidative stress in rat striatum. Neuroreport. 9:559–563.
   PubMed Web of Science ®Google Scholar
• Li T, Lindsley K, Rouse B, Hong H, Shi Q, Friedman DS, Wormald R, Dickersin K. 2016. Comparative effectiveness of first-line medications for primary open-angle glaucoma: a systematic review and network meta-analysis. Ophthalmology. 123:129–140.
   PubMed Web of Science ®Google Scholar
• Maroto R, Kurosky A, Hamill OP. 2012. Mechanosensitive Ca2+ permeant cation channels in human prostate tumor cells. Channels (Austin). 6:290–307.
   PubMed Web of Science ®Google Scholar
• Merritt JE, Jacob R, Hallam TJ. 1989. Use of manganese to discriminate between calcium influx and mobilization from internal stores in stimulated human neutrophils. J Biol Chem. 264:1522–1527.
   PubMed Web of Science ®Google Scholar
• Morita K, Sakakibara A, Kitayama S, et al. 2002. Pituitary adenylate cyclase-activating polypeptide induces a sustained increase in intracellular free Ca2+ concentration and catechol amine release by activating Ca2+ influx via receptor-stimulated Ca2+ entry, independent of store-operated Ca2+ channels, and voltage-dependent Ca2+ channels in bovine adrenal medullary chromaffin cells. J Pharmacol Exp Ther. 302:972–982.
   PubMed Web of Science ®Google Scholar
• Passo MS, Palmer EA, Van Buskirk EM. 1984. Plasma timolol in glaucoma patients. Ophthalmology. 91:1361–1363.
   PubMed Web of Science ®Google Scholar
• Peng G, Ran P, Lu W, Zhong N, Wang J. 2013. Acute hypoxia activates store-operated Ca(2+) entry and increases intracellular Ca(2+) concentration in rat distal pulmonary venous smooth muscle cells. J Thorac Dis. 5:605–612.
   PubMed Web of Science ®Google Scholar
• Prakriya M, Lewis RS. 2015. Store-operated calcium channels. Physiol Rev. 95:1383–1436.
   PubMed Web of Science ®Google Scholar
• Putney JW. Jr. 1986. A model for receptor-regulated calcium entry. Cell Calcium.Calcium7:1–12.
   PubMed Web of Science ®Google Scholar
• Sánchez A, Contreras C, Climent B, Gutiérrez A, Muñoz M, García-Sacristán A, López M, Rivera L, Prieto D. 2018. Impaired Ca2+ handling in resistance arteries from genetically obese Zucker rats: Role of the PI3K, ERK1/2 and PKC signaling pathways. Biochem Pharmacol. 152:114–128.
   PubMed Web of Science ®Google Scholar
• Saarinen-Savolainen P, Järvinen T, Araki-Sasaki K, et al. 1998. Evaluation of cytotoxicity of various ophthalmic drugs, eye drop excipients and cyclodextrins in an immortalized human corneal epithelial cell line. Pharm Res. 15:1275–1280.
   PubMed Web of Science ®Google Scholar
• Schmitz-Peiffer C. 2018. Anarchy in the UPR: A Ca2+-insensitive PKC inhibits SERCA activity to promote ER stress. Biosci Rep. [Epub ahead of print]
   PubMed Web of Science ®Google Scholar
• Staatz WD, Radius RL, Van Horn DL, Schultz RO. 1981. Effects of timolol on bovine corneal endothelial cultures. Arch Ophthalmol. 99:660–663.
   PubMed Web of Science ®Google Scholar
• Takatsu H, Takayama M, Naito T, Takada N, Tsumagari K, Ishihama Y, Nakayama K, Shin H-W. 2017. Phospholipid flippase ATP11C is endocytosed and downregulated following Ca2+-mediated protein kinase C activation. Nat Commun. 8:1423.
   PubMed Web of Science ®Google Scholar
• Thastrup O, Cullen PJ, Drøbak BK, Hanley MR, Dawson AP. 1990. Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase. Proc Natl Acad Sci USA. 87:2466–2470.
   PubMed Web of Science ®Google Scholar
• Thompson AK, Mostafapour SP, Denlinger LC, et al. 1991. The aminosteroid U-73122 inhibits muscarinic receptor sequestration and phosphoinositide hydrolysis in SK-N-SH neuroblastoma cells. A role for Gp in receptor compartmentation. J Biol Chem. 266:23856–23862.
   PubMed Web of Science ®Google Scholar
• Tsien RY. 1980. New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures. Biochemistry. 19:2396–2404.
   PubMed Web of Science ®Google Scholar
• Tuncay E, Okatan EN, Vassort G, Turan B. 2013. ß-blocker timolol prevents arrhythmogenic Ca2+ release and normalizes Ca2+ and Zn2+ dyshomeostasis in hyperglycemic rat heart. PLoS One. 8:e71014.
   PubMed Web of Science ®Google Scholar
• Vescovi G, Weber B, Matrat M, Ramacci C, Nabet P, Kremer B. 1988. Modulation by palmitoyl-carnitine of calcium activated, phospholipid-dependent protein kinase activity and inhibition of melanoma cell growth. Br J Dermatol. 119:171–178.
   PubMed Web of Science ®Google Scholar
• Vuori ML, Ali-Melkkilä T, Kaila T, Iisalo E, Saari KM. 1993. Plasma and aqueous humour concentrations and systemic effects of topical betaxolol and timolol in man. Acta Ophthalmol (Copenh). 71:201–206.
   PubMed Web of Science ®Google Scholar
• Vuori ML, Kaila T. 1995. Plasma kinetics and antagonist activity of topical ocular timolol in elderly patients. Graefes Arch Clin Exp Ophthalmol. 233:131–134.
   PubMed Web of Science ®Google Scholar
• Wang Y, Yue D, Li K, Liu Y-L, Ren C-S, Wang P. 2010. The role of TRPC6 in HGF-induced cell proliferation of human prostate cancer DU145 and PC3 cells. Asian J Androl. 12:841–852.
   PubMed Web of Science ®Google Scholar
• Wu KY, Wang HZ, Hong SJ. 2007. Cellular cytotoxicity of antiglaucoma drugs in cultured corneal endothelial cells. Kaohsiung J Med Sci. 23:105–111.
   PubMed Web of Science ®Google Scholar
• Wu KY, Hong SJ, Wang HZ. 2006. Effects of antiglaucoma drugs on calcium mobility in cultured corneal endothelial cells. Kaohsiung J Med Sci. 22:60–67.
   PubMedGoogle Scholar
• Wu KY, Wang HZ, Hong SJ. 2004. Inhibition of endothelin-1 and KCl-induced increase of [Ca2+]i by antiglaucoma drugs in cultured A7r5 vascular smooth-muscle cells. J Ocul Pharmacol Ther. 20:201–209.
   PubMed Web of Science ®Google Scholar
• Yee NS. 2015. Roles of TRPM8 ion channels in cancer: Proliferation, survival, and invasion. Cancers (Basel). 7:2134–2146.
   PubMed Web of Science ®Google Scholar
• Yeh J-H, Chou C-T, Chen I-S, Lu T, Lin K-L, Yu C-C, Liang W-Z, Chang H-T, Kuo C-C, Ho C-M, et al. 2017. Effect of thymol on Ca2+ homeostasis and viability in PC3 human prostate cancer cells. Chin J Physiol. 60:32–40.
   PubMed Web of Science ®Google Scholar
• Zhang J, Wier WG, Blaustein MP. 2002. Mg2+ blocks myogenic tone but not K+-induced constriction: role for SOCs in small arteries. Am J Physiol Heart Circ Physiol. 283:H2692–H2705.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Ji H, Wang J, Sun Y, Qian Z, Jiang X, Snutch TP, Sun Y, Tao J. 2018. Melatonin-mediated inhibition of Cav3.2 T-type Ca2+ channels induces sensory neuronal hypoexcitability through the novel protein kinase C-eta isoform. J Pineal Res. 64:e12476.
   PubMed Web of Science ®Google Scholar