Design of a microfluidic lung chip and its application in assessing the toxicity of formaldehyde

References

• Benam KH, Dauth S, Hassell B, Herland A, Jain A, Jang KJ, Karalis K, Kim HJ, MacQueen L, Mahmoodian R, et al. 2015. Engineered in vitro disease models. Annu Rev Pathol. 10:195–262.
   PubMed Web of Science ®Google Scholar
• Benam KH, Villenave R, Lucchesi C, Varone A, Hubeau C, Lee H-H, Alves SE, Salmon M, Ferrante TC, Weaver JC, et al. 2016. Small airway-on-a-chip enables analysis of human lung inflammation and drug responses in vitro. Nat Methods. 13(2):151–157.
   PubMed Web of Science ®Google Scholar
• FDA, Center for Tobacco Products. 2012. Harmful and potentially harmful constituents in tobacco products and tobacco smoke: established list. https://www.fda.gov/tobacco-products/rules-regulations-and-guidance/harmful-and-potentially-harmful-constituents-tobacco-products-and-tobacco-smoke-established-list.
   Google Scholar
• Francis I, Shrestha J, Paudel KR, Hansbro PM, Warkiani ME, Saha SC. 2022. Recent advances in lung-on-a-chip models. Drug Discov Today. 27(9):2593–2602.
   PubMed Web of Science ®Google Scholar
• Fricker M, Deane A, Hansbro PM. 2014. Animal models of chronic obstructive pulmonary disease. Expert Opin Drug Discov. 9(6):629–645.
   PubMed Web of Science ®Google Scholar
• Goldizen FC, Sly PD, Knibbs LD. 2016. Respiratory effects of air pollution on children. Pediatr Pulmonol. 51(1):94–108.
   PubMed Web of Science ®Google Scholar
• Graepel R, Ter Braak B, Escher SE, Fisher C, Gardner I, Kamp H, Kroese D, Leist M, Moné MJ, Pastor M, et al. 2019. Paradigm shift in safety assessment using new approach methods: the EU-ToxRisk strategy. Curr Opin Toxicol. 15:33–39.
   Google Scholar
• Gulec M, Gurel A, Armutcu F. 2006. Vitamin E protects against oxidative damage caused by formaldehyde in the liver and plasma of rats. Mol Cell Biochem. 290(1–2):61–67.
   PubMed Web of Science ®Google Scholar
• Hou W, Hu S, Li C, Ma H, Wang Q, Meng G, Guo T, Zhang J. 2019. Cigarette smoke induced lung barrier dysfunction, EMT, and tissue remodeling: a possible link between COPD and lung cancer. Biomed Res Int. 2019:2025636.
   PubMed Web of Science ®Google Scholar
• Ingber DE. 2020. Is it time for reviewer 3 to request human organ chip experiments instead of animal validation studies? Adv Sci. 7(22):2002030.
   Web of Science ®Google Scholar
• Ingber DE. 2022. Human organs-on-chips for disease modelling, drug development and personalized medicine. Nat Rev Genet. 23(8):467–491.
   PubMed Web of Science ®Google Scholar
• Iskandar AR, Mathis C, Martin F, Leroy P, Sewer A, Majeed S, Kuehn D, Trivedi K, Grandolfo D, Cabanski M, et al. 2017. 3-D nasal cultures: systems toxicological assessment of a candidate modified-risk tobacco product. Altex. 34(1):23–48.
   PubMedGoogle Scholar
• Kapałczyńska M, Kolenda T, Przybyła W, Zajączkowska M, Teresiak A, Filas V, Ibbs M, Bliźniak R, Łuczewski Ł, Lamperska K. 2018. 2D and 3D cell cultures – a comparison of different types of cancer cell cultures. Arch Med Sci. 14(4):910–919.
   PubMed Web of Science ®Google Scholar
• Li H, Cheng F, Wang Z, Li W, Robledo-Lara JA, Zhang YS. 2022. 3D-printed, configurable, paper-based, and autonomous multi-organ-on-paper platforms. Mol Syst Des Eng. 7(11):1538–1548.
   Web of Science ®Google Scholar
• Liu XJ, Hu SW, Xu BY, Zhao G, Li X, Xie FW, Xu JJ, Chen HY. 2018. Microfluidic liquid-air dual-gradient chip for synergic effect bio-evaluation of air pollutant. Talanta. 182:202–209.
   PubMed Web of Science ®Google Scholar
• Martinez FJ, Donohue JF, Rennard SI. 2011. The future of chronic obstructive pulmonary disease treatment–difficulties of and barriers to drug development. Lancet. 378(9795):1027–1037.
   PubMed Web of Science ®Google Scholar
• Miller FJ, Conolly RB, Kimbell JS. 2017. An updated analysis of respiratory tract cells at risk for formaldehyde carcinogenesis. Inhal Toxicol. 29(12–14):586–597.
   PubMed Web of Science ®Google Scholar
• Nawroth JC, Lucchesi C, Cheng D, Shukla A, Ngyuen J, Shroff T, Varone A, Karalis K, Lee HH, Alves S, et al. 2020. A microengineered airway lung chip models key features of viral-induced exacerbation of asthma. Am J Respir Cell Mol Biol. 63(5):591–600.
   PubMed Web of Science ®Google Scholar
• Nielsen GD, Larsen ST, Wolkoff P. 2017. Re-evaluation of the WHO (2010) formaldehyde indoor air quality guideline for cancer risk assessment. Arch Toxicol. 91(1):35–61.
   PubMed Web of Science ®Google Scholar
• Nitsche KS, Müller I, Malcomber S, Carmichael PL, Bouwmeester H. 2022. Implementing organ-on-chip in a next-generation risk assessment of chemicals: a review. Arch Toxicol. 96(3):711–741.
   PubMed Web of Science ®Google Scholar
• Sakolish C, Georgescu A, Huh DD, Rusyn I. 2022. A model of human small airway on a chip for studies of subacute effects of inhalation toxicants. Toxicol Sci. 187(2):267–278.
   PubMed Web of Science ®Google Scholar
• Shintu L, Baudoin R, Navratil V, Prot J-M, Pontoizeau C, Defernez M, Blaise BJ, Domange C, Péry AR, Toulhoat P, et al. 2012. Metabolomics-on-a-chip and predictive systems toxicology in microfluidic bioartificial organs. Anal Chem. 84(4):1840–1848.
   PubMed Web of Science ®Google Scholar
• Tang X, Bai Y, Duong A, Smith MT, Li L, Zhang L. 2009. Formaldehyde in China: production, consumption, exposure levels, and health effects. Environ Int. 35(8):1210–1224.
   PubMed Web of Science ®Google Scholar
• Tang XQ, Ren YK, Chen RQ, Zhuang YY, Fang HR, Xu JH, Wang CY, Hu B. 2011. Formaldehyde induces neurotoxicity to PC12 cells involving inhibition of paraoxonase-1 expression and activity. Clin Exp Pharmacol Physiol. 38(4):208–214.
   PubMed Web of Science ®Google Scholar
• Theobald J, Ghanem A, Wallisch P, Banaeiyan AA, Andrade-Navarro MA, Taškova K, Haltmeier M, Kurtz A, Becker H, Reuter S, et al. 2018. Liver-kidney-on-chip to study toxicity of drug metabolites. ACS Biomater Sci Eng. 4(1):78–89.
   PubMed Web of Science ®Google Scholar
• Varone A, Nguyen JK, Leng L, Barrile R, Sliz J, Lucchesi C, Wen N, Gravanis A, Hamilton GA, Karalis K, et al. 2021. A novel organ-chip system emulates three-dimensional architecture of the human epithelia and the mechanical forces acting on it. Biomaterials. 275:120957.
   PubMed Web of Science ®Google Scholar
• Westmoreland C, Bender HJ, Doe JE, Jacobs MN, Kass GEN, Madia F, Mahony C, Manou I, Maxwell G, Prieto P, et al. 2022. Use of New Approach Methodologies (NAMs) in regulatory decisions for chemical safety: report from an EPAA Deep Dive Workshop. Regul Toxicol Pharmacol. 135:105261.
   PubMed Web of Science ®Google Scholar
• Xia J, Xiong Z, Guo J, Wang Y, Luo Y, Sun Y, Guo Z, Lu B, Zhang T, Sun W. 2023. Study of paraquat-induced pulmonary fibrosis using biomimetic micro-lung chips. Biofabrication. 15(1):014104.
   Web of Science ®Google Scholar
• Zhang BY, Shi YQ, Chen X, Dai J, Jiang ZF, Li N, Zhang ZB. 2013. Protective effect of curcumin against formaldehyde-induced genotoxicity in A549 cell lines. J Appl Toxicol. 33(12):1468–1473.
   PubMed Web of Science ®Google Scholar
• Zhang F, Liu W, Zhou S, Jiang L, Wang K, Wei Y, Liu A, Wei W, Liu S. 2020. Investigation of environmental pollutant-induced lung inflammation and injury in a 3D coculture-based microfluidic pulmonary alveolus system. Anal Chem. 92(10):7200–7208.
   PubMed Web of Science ®Google Scholar