1,438
Views
21
CrossRef citations to date
0
Altmetric
Research Paper

GATA-3 augmentation down-regulates Connexin43 in Helicobacter pylori associated gastric carcinogenesis

, , , , , , , , & show all
Pages 987-996 | Received 27 Feb 2015, Accepted 09 Mar 2015, Published online: 29 May 2015

References

  • Saez JC, Berthoud VM, Branes MC, Martinez AD, Beyer EC. Plasma membrane channels formed by connexins: their regulation and functions. Physiol Rev 2003; 83:1359-400; PMID:14506308; http://dx.doi.org/10.1152/physrev.00007.2003
  • Panani AD. Cytogenetic and molecular aspects of gastric cancer: clinical implications. Cancer Lett 2008; 266:99-115; PMID:18381231; http://dx.doi.org/10.1016/j.canlet.2008.02.053
  • Tang B, Peng ZH, Yu PW, Yu G, Qian F, Zeng DZ, Zhao YL, Shi Y, Hao YX, Luo HX. Aberrant expression of Cx43 is associated with the peritoneal metastasis of gastric cancer and Cx43-mediated gap junction enhances gastric cancer cell diapedesis from peritoneal mesothelium. Plos One 2013; 11(9): 274527; 8:PMID:24040271; http://dx.doi.org/10.1371/journal.pone.0074527
  • Xu CX, Jia Y, Yang WB, Wang F, Shen SR. [Relationship between Helicobacter pylori infection and expression of connexin (Cx) 32 and Cx43 genes in gastric cancer and gastric precancerous lesions]. Zhonghua yi xue za zhi 2008; 88:1523-7; PMID:18956631
  • Parsonnet J, Friedman GD, Vandersteen DP, Chang Y, Vogelman JH, Orentreich N, Sibley RK. Helicobacter pylori infection and the risk of gastric carcinoma. New Engl J Med 1991; 325:1127-31; PMID:1891020; http://dx.doi.org/10.1056/NEJM199110173251603
  • Yokozaki H. Molecular characteristics of eight gastric cancer cell lines established in Japan. Pathol Int 2000; 50:767-77; PMID:11107048; http://dx.doi.org/10.1046/j.1440-1827.2000.01117.x
  • Xu CX, Qi YM, Yang WB, Wang F, Zhou JD, Shen SR. ; [Effect of CagA(+) helicobacter pylori strain on the expression of connexin 43 and cell proliferation in BGC-823 cells]. Zhong nan da xue xue bao Yi xue ban 2007; 32:288-94; PMID:17478938
  • Leithe E, Rivedal E. Ubiquitination of gap junction proteins. J Membrane Biol 2007; 217:43-51; PMID:21866551; http://dx.doi.org/10.1007/s00232-007-9050-z
  • Cottrell GT, Lin R, Warn-Cramer BJ, Lau AF, Burt JM. Mechanism of v-Src- and mitogen-activated protein kinase-induced reduction of gap junction communication. Am J Physiol Cell Physiol 2003; 284:C511-20; PMID:12388103; http://dx.doi.org/10.1152/ajpcell.00214.2002
  • Matesic DF, Sidorova TS, Burns TJ, Bell AM, Tran PL, Ruch RJ, May SW. p38 MAPK activation, JNK inhibition, neoplastic growth inhibition, and increased gap junction communication in human lung carcinoma and Ras-transformed cells by 4-Phenyl-3-butenoic acid. J Cell Biochem 2012; 113:269-81; PMID:21898549; http://dx.doi.org/10.1002/jcb.23353
  • Maneechotesuwan K, Xin Y, Ito K, Jazrawi E, Lee KY, Usmani OS, Barnes PJ, Adcock IM. Regulation of Th2 cytokine genes by p38 MAPK-mediated phosphorylation of GATA-3. J Immunol 2007; 178:2491-8; PMID:17277157; http://dx.doi.org/10.4049/jimmunol.178.4.2491
  • Ko JA, Yanai R, Morishige N, Takezawa T, Nishida T. Upregulation of connexin43 expression in corneal fibroblasts by corneal epithelial cells. Invest Ophthal Visual Sci 2009; 50:2054-60; PMID:19117926; http://dx.doi.org/10.1167/iovs.08-2418
  • Ghosh S, Kumar A, Tripathi RP, Chandna S. Connexin-43 regulates p38-mediated cell migration and invasion induced selectively in tumour cells by low doses of gamma-radiation in an ERK-1/2-independent manner. Carcinogenesis 2014; 35:383-95; PMID:24045413; http://dx.doi.org/10.1093/carcin/bgt303
  • Xu C, Chen Y, Chen X, Wang F. Effects of different types of helicobacter pylori on the gap junction intercellular communication in GES-1 cells. Zhong nan da xue xue bao Yi xue ban 2011; 36:294-300; PMID:21566279; http://dx.doi.org/10.3969/j.issn.1672-7347.2011.04.003
  • Jimenez T, Fox WP, Naus CCG, Galipeau J, Belliveau DJ. Connexin over-expression differentially suppresses glioma growth and contributes to the bystander effect following HSV-thymidine kinase gene therapy. Cell Commun Adhes 2006; 13:79-92; PMID:16613782; http://dx.doi.org/10.1080/15419060600631771
  • Kretz M, Euwens C, Hombach S, Eckardt D, Teubner B, Traub O, Willecke K, Ott T. Altered connexin expression and wound healing in the epidermis of connexin-deficient mice. J Cell Sci 2003; 116:3443-52; PMID:12840073; http://dx.doi.org/10.1242/jcs.00638
  • Aasen T, Hodgins MB, Edward M, Graham SV. The relationship between connexins, gap junctions, tissue architecture and tumour invasion, as studied in a novel in vitro model of HPV-16-associated cervical cancer progression. Oncogene 2003; 22:7969-80; PMID:12970745; http://dx.doi.org/10.1038/sj.onc.1206709
  • Pai SY, Truitt ML, Ting CN, Leiden JM, Glimcher LH, Ho IC. Critical roles for transcription factor GATA-3 in thymocyte development. Immunity 2003; 19:863-75; PMID:14670303; http://dx.doi.org/10.1016/S1074-7613(03)00328-5
  • Ellis CL, Chang AG, Cimino-Mathews A, Argani P, Youssef RF, Kapur P, Montgomery EA, Epstein JI. GATA-3 Immunohistochemistry in the differential diagnosis of adenocarcinoma of the urinary bladder. Am J Surg Pathol 2013; 37:1756-60; PMID:24061521; http://dx.doi.org/10.1097/PAS.0b013e31829cdba7
  • Jacquemier J, Charafe-Jauffret E, Monville F, Esterni B, Extra JM, Houvenaeghel G, Xerri L, Bertucci F, Birnbaum D. Association of GATA3, P53, Ki67 status and vascular peritumoral invasion are strongly prognostic in luminal breast cancer. Breast Cancer Res 2009; 11(2): R23; PMID:19405945; http://dx.doi.org/10.1186/bcr2249
  • Molenaar JJ, Ebus ME, Koster J, Santo E, Geerts D, Versteeg R, Caron HN. Cyclin D1 is a direct transcriptional target of GATA3 in neuroblastoma tumor cells. Oncogene 2010; 29:2739-45; PMID:20154722; http://dx.doi.org/10.1038/onc.2010.21
  • Asselin-Labat ML, Sutherland KD, Barker H, Thomas R, Shackleton M, Forrest NC, Hartley L, Robb L, Grosveld FG, van der Wees J. Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation. Nat Cell Biol 2007; 9:201-U103; PMID:17187062; http://dx.doi.org/10.1038/ncb1530
  • Kouros-Mehr H, Bechis SK, Slorach EM, Littlepage LE, Egeblad M, Ewald AJ, Pai SY, Ho IC, Werb Z. GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model. Cancer Cell 2008; 13:141-52; PMID:18242514; http://dx.doi.org/10.1016/j.ccr.2008.01.011
  • Voronov E, Shouval DS, Krelin Y, Cagnano E, Benharroch D, Iwakura Y, Dinarello CA, Apte RN. IL-1 is required for tumor invasiveness and angiogenesis. P Natl Acad Sci USA 2003; 100:2645-50; PMID:12598651; http://dx.doi.org/10.1073/pnas.0437939100
  • Jackson JA, Hall AJ, Friberg IM, Ralli C, Lowe A, Zawadzka M, Turner AK, Stewart A, Birtles RJ, Paterson S. et al. An immunological marker of tolerance to infection in wild rodents. Plos Biol 2014; 12(7): e1001901; PMID:25004450; http://dx.doi.org/10.1371/journal.pbio.1001901
  • Stellato C, Gubin MM, Magee JD, Fang X, Fan JS, Tartar DM, Chen J, Dahm GM, Calaluce R, Mori F., et al. Coordinate regulation of GATA-3 and Th2 cytokine gene expression by the RNA-binding protein HuR. J Immunol 2011; 187:441-9; PMID:21613615; http://dx.doi.org/10.4049/jimmunol.1001881
  • Apte SH, Groves P, Olver S, Baz A, Doolan DL, Kelso A, Kienzle N. IFN-gamma inhibits IL-4-induced type 2 cytokine expression by CD8 T cells in vivo and modulates the anti-tumor response. J Immunol 2010; 185:998-1004; PMID:20562261; http://dx.doi.org/10.4049/jimmunol.0903372
  • Lindgren A, Yun CH, Sjoling A, Berggren C, Sun JB, Jonsson E, Holmgren J, Svennerholm AM, Lundin SB. Impaired IFN-gamma production after stimulation with bacterial components by natural killer cells from gastric cancer patients. Exp Cell Res 2011; 317:849-58; PMID:21255568; http://dx.doi.org/10.1016/j.yexcr.2011.01.006
  • Sayi A, Kohler E, Toller IM, Flavell RA, Muller W, Roers A, Müller A. TLR-2-activated B cells suppress helicobacter-induced preneoplastic gastric immunopathology by inducing T regulatory-1 cells. J Immunol 2011; 186:878-90; PMID:21149607; http://dx.doi.org/10.4049/jimmunol.1002269
  • Khan MM, Chatterjee S, Dwivedi VP, Pandey NK, Singh Y, Tousif S, Bhavesh NS, Van Kaer L, Das J, Das G. CD4(+) T cell-derived novel peptide Thp5 induces interleukin-4 production in CD4(+) T cells to direct T helper 2 cell differentiation. J Biol Chem 2012; 287:2830-5; PMID:22130674; http://dx.doi.org/10.1074/jbc.M111.319947
  • Hou L, El-Omar EM, Chen J, Grillo P, Rabkin CS, Baccarelli A, Yeager M, Chanock SJ, Zatonski W, Sobin LH., et al. Polymorphisms in Th1-type cell-mediated response genes and risk of gastric cancer. Carcinogenesis 2007; 28:118-23; PMID:16885196; http://dx.doi.org/10.1093/carcin/bgl130
  • Straubinger RK, Greiter A, McDonough SP, Gerold A, Scanziani E, Soldati S, et al. Quantitative evaluation of inflammatory and immune responses in the early stages of chronic Helicobacter pylori infection. Infect Immun 2003; 71:2693-703; PMID:12704144; http://dx.doi.org/10.1128/IAI.71.5.2693-2703.2003
  • Enarsson K, Lundgren A, Kindlund B, Hermansson M, Roncador G, Banham AH, et al. Function and recruitment of mucosal regulatory T cells in human chronic Helicobacter pylori infection and gastric adenocarcinoma. Clin Immunol 2006; 121:358-68; PMID:16934529; http://dx.doi.org/10.1016/j.clim.2006.07.002
  • Yang P, Qiu G, Wang S, Su Z, Chen J, Wang S, et al. The mutations of Th1 cell-specific T-box transcription factor may be associated with a predominant Th2 phenotype in gastric cancers. Int J Immunogenet 2010; 37:111-5; PMID:20193034; http://dx.doi.org/10.1111/j.1744-313X.2010.00899.x
  • Liu Z, Xu X, Chen L, Li W, Sun Y, Zeng J, et al. Helicobacter pylori CagA inhibits the expression of Runx3 via Src/MEK/ERK and p38 MAPK pathways in gastric epithelial cell. J Cell Biochem 2012; 113:1080-6; PMID:22266963; http://dx.doi.org/10.1002/jcb.23440
  • King TJ, Gurley KE, Prunty J, Shin JL, Kemp CJ, Lampe PD. Deficiency in the gap junction protein connexin32 alters p27Kip1 tumor suppression and MAPK activation in a tissue-specific manner. Oncogene 2005; 24:1718-26; PMID:15608667; http://dx.doi.org/10.1038/sj.onc.1208355
  • Goldman M, Craft B, Swatloski T, Ellrott K, Cline M, Diekhans M, Dailidiene D, Dailide G, Berg DE, Simpson KW. The UCSC cancer genomics browser: update 2013. Nucleic Acids Res 2013; 41:D949-D54; PMID:23109555; http://dx.doi.org/10.1093/nar/gks1008
  • Wingender E. The TRANSFAC project as an example of framework technology that supports the analysis of genomic regulation. Brief Bioinform 2008; 9:326-32; PMID:18436575; http://dx.doi.org/10.1093/bib/bbn016

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.