Cancer Biology & Therapy, Volume 16, Issue 6 (2015)

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Cancer Biology & Therapy, Volume 16, Issue 6 (2015)

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Review

Review Article
Tumor infiltrating lymphocytes in ovarian cancer
Phillip P Santoiemma & Daniel J Powell Jr
Pages: 807-820
Published online: 29 May 2015
AbstractforTumor infiltrating lymphocytes in ovarian cancer | Full Text | References | PDF (509.5 KB)
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Review Article
LB100, a small molecule inhibitor of PP2A with potent chemo- and radio-sensitizing potential
Christopher S Hong, Winson Ho, Chao Zhang, Chunzhang Yang, J Bradley Elder & Zhengping Zhuang
Pages: 821-833
Published online: 28 May 2015
AbstractforLB100, a small molecule inhibitor of PP2A with potent chemo- and radio-sensitizing potential | Full Text | References | PDF (262.3 KB)
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Bedside to Bench Report

Article
Analysis and significance of c-MET expression in adenoid cystic carcinoma of the salivary gland
Diana Bell, Renata Ferrarotto, Melanie D Fox, Dianna Roberts, Ehab Y Hanna, Randal S Weber & Adel K El-Naggar
Pages: 834-838
Published online: 29 May 2015
AbstractforAnalysis and significance of c-MET expression in adenoid cystic carcinoma of the salivary gland | Full Text | References | PDF (640.2 KB)
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Clinical Study

Article
Overexpression of pyruvate kinase M2 associates with aggressive clinicopathological features and unfavorable prognosis in oral squamous cell carcinoma
Yanling Wang, Xiaomin Zhang, Yuchao Zhang, Yuming Zhu, Chunping Yuan, Bin Qi, Wei Zhang, Dongmiao Wang, Xu Ding, Heming Wu & Jie Cheng
Pages: 839-845
Published online: 22 May 2015
AbstractforOverexpression of pyruvate kinase M2 associates with aggressive clinicopathological features and unfavorable prognosis in oral squamous cell carcinoma | Full Text | References | PDF (499 KB)
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Research Paper

Article
miR-33a functions as a tumor suppressor in melanoma by targeting HIF-1α
Jianda Zhou, Dan Xu, Huiqing Xie, Jingtian Tang, Rui Liu, Jingjing Li, Shaohua Wang, Xiang Chen, Juan Su, Xiao Zhou, Kun Xia, Quanyong He, Jia Chen, Wei Xiong, Peiguo Cao & Ke Cao
Pages: 846-855
Published online: 11 Jun 2015
AbstractformiR-33a functions as a tumor suppressor in melanoma by targeting HIF-1α | Full Text | References | PDF (863.9 KB) | Supplemental
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Article
Microarray expression profiling of dysregulated long non-coding RNAs in triple-negative breast cancer
Chen Chen, Zhilu Li, Yuan Yang, Tingxiu Xiang, Weihong Song & Shengchun Liu
Pages: 856-865
Published online: 11 Jun 2015
AbstractforMicroarray expression profiling of dysregulated long non-coding RNAs in triple-negative breast cancer | Full Text | References | PDF (665.2 KB) | Supplemental
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Article
Down-regulating HIF-1α by lentivirus-mediated shRNA for therapy of triple negative breast cancer
Shuang Li, Qingzhu Wei, Qin Li, Bin Zhang & Qiang Xiao
Pages: 866-875
Published online: 11 Jun 2015
AbstractforDown-regulating HIF-1α by lentivirus-mediated shRNA for therapy of triple negative breast cancer | Full Text | References | PDF (1.2 MB)
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Article
MIEN1 promotes oral cancer progression and implicates poor overall survival
Smrithi Rajendiran, Marilyne Kpetemey, Sayantan Maji, Lee D Gibbs, Subhamoy Dasgupta, Rebecca Mantsch, Richard J Hare & Jamboor K Vishwanatha
Pages: 876-885
Published online: 11 Jun 2015
AbstractforMIEN1 promotes oral cancer progression and implicates poor overall survival | Full Text | References | PDF (936.5 KB)
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Article
Adipose tissue lipolysis and energy metabolism in early cancer cachexia in mice
Kara L Kliewer, Jia-Yu Ke, Min Tian, Rachel M Cole, Rebecca R Andridge & Martha A Belury
Pages: 886-897
Published online: 22 May 2015
AbstractforAdipose tissue lipolysis and energy metabolism in early cancer cachexia in mice | Full Text | References | PDF (713.2 KB)
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Article
Autocrine IL-8 promotes F-actin polymerization and mediate mesenchymal transition via ELMO1-NF-κB-Snail signaling in glioma
Baogang Zhang, Lihong Shi, Shijun Lu, Xiuning Sun, Yuqing Liu, Hongli Li, Xuejian Wang, Chunzhen Zhao, Heng Zhang & Ying Wang
Pages: 898-911
Published online: 22 May 2015
AbstractforAutocrine IL-8 promotes F-actin polymerization and mediate mesenchymal transition via ELMO1-NF-κB-Snail signaling in glioma | Full Text | References | PDF (1.1 MB) | Supplemental
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Article
Hyperglycemic tumor microenvironment induces perineural invasion in pancreatic cancer
Junhui Li, Jiguang Ma, Liang Han, Qinhong Xu, Jianjun Lei, Wanxing Duan, Wei Li, Fengfei Wang, Erxi Wu, Qingyong Ma & Xiongwei Huo
Pages: 912-921
Published online: 22 May 2015
AbstractforHyperglycemic tumor microenvironment induces perineural invasion in pancreatic cancer | Full Text | References | PDF (1.2 MB) | Supplemental
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Article
Molecular inhibition of prostaglandin E2 with GW627368X: Therapeutic potential and preclinical safety assessment in mouse sarcoma model
Sheetal Parida, Aditya Parekh, Goutam Dey, Sukhen C Ghosh & Mahitosh Mandal
Pages: 922-932
Published online: 22 May 2015
AbstractforMolecular inhibition of prostaglandin E2 with GW627368X: Therapeutic potential and preclinical safety assessment in mouse sarcoma model | Full Text | References | PDF (1.1 MB)
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Article
EGFR inhibitors prevent induction of cancer stem-like cells in esophageal squamous cell carcinoma by suppressing epithelial-mesenchymal transition
Fumiyuki Sato, Yoshimasa Kubota, Mitsuteru Natsuizaka, Osamu Maehara, Yutaka Hatanaka, Katsuji Marukawa, Katsumi Terashita, Goki Suda, Shunsuke Ohnishi, Yuichi Shimizu, Yoshito Komatsu, Shinya Ohashi, Shingo Kagawa, Hideaki Kinugasa, Kelly A Whelan, Hiroshi Nakagawa & Naoya Sakamoto
Pages: 933-940
Published online: 28 May 2015
AbstractforEGFR inhibitors prevent induction of cancer stem-like cells in esophageal squamous cell carcinoma by suppressing epithelial-mesenchymal transition | Full Text | References | PDF (708.1 KB) | Supplemental
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Article
MiR-15a and miR-16 induce autophagy and enhance chemosensitivity of Camptothecin
Nunu Huang, Jiangbin Wu, Wei Qiu, Qing Lyu, Jie He, Weidong Xie, Naihan Xu & Yaou Zhang
Pages: 941-948
Published online: 28 May 2015
AbstractforMiR-15a and miR-16 induce autophagy and enhance chemosensitivity of Camptothecin | Full Text | References | PDF (656.6 KB)
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Article
The HSP90 inhibitor alvespimycin enhances the potency of telomerase inhibition by imetelstat in human osteosarcoma
Yafang Hu, Daniel Bobb, Jianping He, D Ashley Hill & Jeffrey S Dome
Pages: 949-957
Published online: 28 May 2015
AbstractforThe HSP90 inhibitor alvespimycin enhances the potency of telomerase inhibition by imetelstat in human osteosarcoma | Full Text | References | PDF (621.2 KB)
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Article
Early treatment with metformin induces resistance against tumor growth in adult rats
Amanda B Trombini, Claudinéia CS Franco, Rosiane A Miranda, Júlio C de Oliveira, Luiz F Barella, Kelly V Prates, Aline A de Souza, Audrei Pavanello, Ananda Malta, Douglas L Almeida, Laize P Tófolo, Kesia P Rigo, Tatiane AS Ribeiro, Gabriel S Fabricio, Juliane R de Sant’Anna, Marialba AA Castro-Prado, Helenir Medri de Souza, Hely de Morais & Paulo CF Mathias
Pages: 958-964
Published online: 29 May 2015
AbstractforEarly treatment with metformin induces resistance against tumor growth in adult rats | Full Text | References | PDF (357.2 KB)
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Article
Inhibition of AKT/FoxO3a signaling induced PUMA expression in response to p53-independent cytotoxic effects of H1: A derivative of tetrandrine
Yin-Xu Zhang, Xiao-Mei Liu, Jing Wang, Jun Li, Ying Liu, Hua Zhang, Xue-Wen Yu & Ning Wei
Pages: 965-975
Published online: 29 May 2015
AbstractforInhibition of AKT/FoxO3a signaling induced PUMA expression in response to p53-independent cytotoxic effects of H1: A derivative of tetrandrine | Full Text | References | PDF (906.6 KB)
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Article
A peptide nucleic acid targeting nuclear RAD51 sensitizes multiple myeloma cells to melphalan treatment
David Abasiwani Alagpulinsa, Shmuel Yaccoby, Srinivas Ayyadevara & Robert Joseph Shmookler Reis
Pages: 976-986
Published online: 29 May 2015
AbstractforA peptide nucleic acid targeting nuclear RAD51 sensitizes multiple myeloma cells to melphalan treatment | Full Text | References | PDF (773.1 KB)
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Article
GATA-3 augmentation down-regulates Connexin43 in Helicobacter pylori associated gastric carcinogenesis
Xiaoming Liu, Ke Cao, Canxia Xu, Tingzi Hu, Li Zhou, Dan Cao, Jing Xiao, Ling Luo, Yinjie Guo & Yong Qi
Pages: 987-996
Published online: 29 May 2015
AbstractforGATA-3 augmentation down-regulates Connexin43 in Helicobacter pylori associated gastric carcinogenesis | Full Text | References | PDF (701.7 KB) | Supplemental
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