MicroRNA signature in the chemoprevention of functionally-enriched stem and progenitor pools (FESPP) by Active Hexose Correlated Compound (AHCC)

References

• Villarini A, Pasanisi P, Traina A, Mano MP, Bonanni B, Panico S, Scipioni C, Galasso R, Paduos A, Simeoni M, et al. Lifestyle and breast cancer recurrences: the DIANA-5 trial. Tumori. 2012;98:1-18. PMID:22495696
   PubMed Web of Science ®Google Scholar
• Cowawintaweewat S, Manoromana S, Sriplung H, Khuhaprema T, Tongtawe P, Tapchaisri P, Tapchaisri P, Chaicumpa W. Prognostic Improvement of patients with advanced liver cancer after Active Hexose Correlated Compound (AHCC) treatment. Asian Pac J Allergy Immunol. 2010;24:33-45.
   Google Scholar
• Hangai S, Iwase S, Kawaguchi T, Kogure Y, Miyaji T, Matsunaga T, Nagumo Y, Yamaguchi T. Effect of active hexose-correlated compound in women receiving adjuvant chemotherapy for breast cancer: a retrospective study. J Altern Complement Med N. Y. N. 2013;19:905-10. doi:10.1089/acm.2012.0914
   PubMed Web of Science ®Google Scholar
• Turner J, Chaudhary U. Dramatic prostate-specific antigen response with activated hemicellulose compound in metastatic castration-resistant prostate cancer. Anticancer Drugs. 2009;20:215-6. doi:10.1097/CAD.0b013e3283163c26. PMID:19104437
   PubMed Web of Science ®Google Scholar
• Hirose A, Sato E, Fujii H, Sun B, Nishioka H, Aruoma OI. The influence of active hexose correlated compound (AHCC) on cisplatin-evoked chemotherapeutic and side effects in tumor-bearing mice. Toxicol Appl Pharmacol. 2007;222:152-8. doi:10.1016/j.taap.2007.03.031. PMID:17555784
   PubMed Web of Science ®Google Scholar
• Okuyama T, Yoshigai E, Ikeya Y, Nishizawa M. Active Hexose Correlated Compound extends the lifespan and increases the thermotolerance of Nematodes. Research Gate. 2013;3:166-82.
   Google Scholar
• Ritz BW, Nogusa S, Ackerman EA, Gardner EM. Supplementation with Active Hexose Correlated Compound increases the innate immune response of young mice to primary influenza infection. J Nutr. 2006;136:2868-73. PMID:17056815
   PubMed Web of Science ®Google Scholar
• Gao Y, Zhang D, Sun B, Fujii H, Kosuna K-I, Yin Z. Active hexose correlated compound enhances tumor surveillance through regulating both innate and adaptive immune responses. Cancer Immunol Immunother. 2006;55:1258-66. doi:10.1007/s00262-005-0111-9. PMID:16362410
   PubMed Web of Science ®Google Scholar
• Daddaoua A, Martínez-Plata E, López-Posadas R, Vieites JM, González M, Requena P, Zarzuelo A, Suárez MD, de Medina FS, Martínez-Augustin O. Active Hexose Correlated Compound acts as a prebiotic and is antiinflammatory in rats with hapten-induced colitis. J Nutr. 2007;137:1222-8. PMID:17449585
   PubMed Web of Science ®Google Scholar
• Lee HE, Kim JH, Kim YJ, Choi SY, Kim S-W, Kang E, Chung IY, Kim IA, Kim EJ, Choi Y, et al. An increase in cancer stem cell population after primary systemic therapy is a poor prognostic factor in breast cancer. Br J Cancer. 2011;104:1730-8. doi:10.1038/bjc.2011.159. PMID:21559013
   PubMed Web of Science ®Google Scholar
• Korkaya H, Liu S, Wicha MS. Regulation of cancer stem cells by cytokine networks: attacking cancer's inflammatory roots. Clin. Cancer Res. 2011;17:6125-9. doi:10.1158/1078-0432.CCR-10-2743. PMID:21685479
   PubMed Web of Science ®Google Scholar
• Iliopoulos D, Polytarchou C, Hatziapostolou M, Kottakis F, Maroulakou IG, Struhl K, Tsichlis PN. MicroRNAs differentially regulated by Akt isoforms control EMT and stem cell renewal in cancer cells. Sci Signal. 2009;2:ra62. doi:10.1126/scisignal.2000356. PMID:19825827
   PubMed Web of Science ®Google Scholar
• Wicha MS, Liu S, Dontu G. Cancer stem cells: An old idea—A paradigm shift. Cancer Res. 2006;66:1883-90. doi:10.1158/0008-5472.CAN-05-3153. PMID:16488983
   PubMed Web of Science ®Google Scholar
• Wicha MS. Cancer stem cells and metastasis: lethal seeds. Clin Cancer Res. 2006;12:5606-7. doi:10.1158/1078-0432.CCR-06-1537. PMID:17020960
   PubMed Web of Science ®Google Scholar
• Lee H-S, Herceg Z. The epigenome and cancer prevention: A complex story of dietary supplementation. Cancer Lett. 2014;342:275-84. doi:10.1016/j.canlet.2012.01.021. PMID:22266189
   PubMed Web of Science ®Google Scholar
• Dontu G, Al-Hajj M, Abdallah WM, Clarke MF, Wicha MS. Stem cells in normal breast development and breast cancer. Cell Prolif. 2003;36 Suppl 1:59-72. doi:10.1046/j.1365-2184.36.s.1.6.x. PMID:14521516
   PubMed Web of Science ®Google Scholar
• Wicha MS. Identification of murine mammary stem cells: implications for studies of mammary development and carcinogenesis. Breast Cancer Res BCR. 2006;8:109. doi:10.1186/bcr1540. PMID:16934104
   PubMed Web of Science ®Google Scholar
• Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF. Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci U. S. A. 2003;100:3983-8. doi:10.1073/pnas.0530291100. PMID:12629218
   PubMed Web of Science ®Google Scholar
• Han M, Liu M, Wang Y, Chen X, Xu J, Sun Y, Zhao L, Qu H, Fan Y, Wu C. Antagonism of miR-21 reverses Epithelial-Mesenchymal Transition and cancer stem cell phenotype through AKT/ERK1/2 inactivation by targeting PTEN. PLoS One. 2012;7:1-11.
   Web of Science ®Google Scholar
• Ellis SL, Heazlewood SY, Williams B, Reitsma AJ, Grassinger J, Borg J, Heazlewood CK, Chidgey AP, Nilsson SK. The role of Tenascin C in the lymphoid progenitor cell niche. Exp Hematol. 2013;41:1050-61. doi:10.1016/j.exphem.2013.09.009. PMID:24084079
   PubMed Web of Science ®Google Scholar
• Oskarsson T, Acharyya S, Zhang XH-F, Vanharanta S, Tavazoie SF, Morris PG, Downey RJ, Manova-Todorova K, Brogi E, Massagué J. Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs. Nat Med. 2011;17:867-74. doi:10.1038/nm.2379. PMID:21706029
   PubMed Web of Science ®Google Scholar
• Midwood KS, Orend G. The role of tenascin-C in tissue injury and tumorigenesis. J Cell Commun Signal. 2009;3:287-310. doi:10.1007/s12079-009-0075-1. PMID:19838819
   PubMed Web of Science ®Google Scholar
• Ruiz C, Huang W, Hegi ME, Lange K, Hamou M-F, Fluri E, Oakeley EJ, Chiquet-Ehrismann R, Orend G. Growth promoting signaling by tenascin-C [corrected]. Cancer Res. 2004;64:7377-85. doi:10.1158/0008-5472.CAN-04-1234. PMID:15492259
   PubMed Web of Science ®Google Scholar
• Tamaoki M, Imanaka-Yoshida K, Yokoyama K, Nishioka T, Inada H, Hiroe M, Sakakura T, Yoshida T. Tenascin-C regulates recruitment of myofibroblasts during tissue repair after myocardial injury. Am J Pathol. 2005;167:71-80. doi:10.1016/S0002-9440(10)62954-9. PMID:15972953
   PubMed Web of Science ®Google Scholar
• Sever M, Mammadov B, Guler MO, Tekinay AB. Tenascin-C mimetic Peptide nanofibers direct stem cell differentiation to osteogenic lineage. Biomacromolecules. 2014;15:4480-7. doi:10.1021/bm501271x. PMID:25343209
   PubMed Web of Science ®Google Scholar
• Goh FG, Piccinini AM, Krausgruber T, Udalova IA, Midwood KS. Transcriptional regulation of the endogenous danger signal tenascin-C: a novel autocrine loop in inflammation. J Immunol Baltim Md 1950. 2010;184:2655-62.
   Google Scholar
• Hendaoui I, Tucker RP, Zingg D, Bichet S, Schittny J, Chiquet-Ehrismann R. Tenascin-C is required for normal Wnt/β-catenin signaling in the whisker follicle stem cell niche. Matrix Biol J Int Soc Matrix Biol. 2014;40:46-53. doi:10.1016/j.matbio.2014.08.017
   PubMed Web of Science ®Google Scholar
• Bellone M, Caputo S, Jachetti E. Immunosuppression via Tenascin-C. Oncoscience. 2015;2:667-8. doi:10.18632/oncoscience.210. PMID:26425650
   PubMedGoogle Scholar
• Liu C, Tang DG. MicroRNA regulation of cancer stem cells. Cancer Res. 2011;71:5950-4. doi:10.1158/0008-5472.CAN-11-1035. PMID:21917736
   PubMed Web of Science ®Google Scholar
• Bao B, Li Y, Ahmad A, Azmi AS, Bao G, Ali S, Banerjee S, Kong D, Sarkar FH. Targeting CSC-related miRNAs for cancer therapy by natural agents. Curr Drug Targets. 2012;13:1858-68. doi:10.2174/138945012804545515. PMID:23140295
   PubMed Web of Science ®Google Scholar
• Shi B, Sepp-Lorenzino L, Prisco M, Linsley P, deAngelis T, Baserga R. Micro RNA 145 targets the insulin receptor substrate-1 and inhibits the growth of colon cancer cells. J Biol Chem. 2007;282:32582-90. doi:10.1074/jbc.M702806200. PMID:17827156
   PubMed Web of Science ®Google Scholar
• Hatfield S, Ruohola-Baker H. microRNA and stem cell function. Cell Tissue Res. 2008;331:57-66. doi:10.1007/s00441-007-0530-3. PMID:17987317
   PubMed Web of Science ®Google Scholar
• Erturk E, Cecener G, Egeli U, Tunca B, Tezcan G, Gokgoz S, Tolunay S, Tasdelen I. Expression status of let-7a and miR-335 among breast tumors in patients with and without germ-line BRCA mutations. Mol Cell Biochem. 2014;395:77-88. doi:10.1007/s11010-014-2113-4. PMID:24942235
   PubMed Web of Science ®Google Scholar
• Gao Y, Zeng F, Wu J-Y, Li H-Y, Fan J-J, Mai L, Zhang J, Ma DM, Li Y, Song FZ. MiR-335 inhibits migration of breast cancer cells through targeting oncoprotein c-Met. Tumour Biol. 2015;36:2875-83. doi:10.1007/s13277-014-2917-6. PMID:25492484
   PubMed Web of Science ®Google Scholar
• Meng Y, Zou Q, Liu T, Cai X, Huang Y, Pan J. microRNA-335 inhibits proliferation, cell-cycle progression, colony formation, and invasion via targeting PAX6 in breast cancer cells. Mol Med Rep. 2015;11:379-85. doi:10.3892/mmr.2014.2684. PMID:25323813
   PubMed Web of Science ®Google Scholar
• Vimalraj S, Miranda PJ, Ramyakrishna B, Selvamurugan N. Regulation of breast cancer and bone metastasis by microRNAs. Dis Markers. 2013;35:369-87. doi:10.1155/2013/451248. PMID:24191129
   PubMed Web of Science ®Google Scholar
• Scarola M, Schoeftner S, Schneider C, Benetti R. miR-335 directly targets Rb1 (pRb/p105) in a proximal connection to p53-dependent stress response. Cancer Res. 2010;70:6925-33. doi:10.1158/0008-5472.CAN-10-0141. PMID:20713524
   PubMed Web of Science ®Google Scholar
• Polytarchou C, Iliopoulos D, Struhl K. An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state. Proc Natl Acad Sci. U. S. A. 2012;109:14470-5. doi:10.1073/pnas.1212811109. PMID:22908280
   PubMed Web of Science ®Google Scholar
• Pulaski BA, Ostrand-Rosenberg S. Mouse 4T1 breast tumor model. Coligan JE, editor. Curr Protoc Immunol. New Jersey (USA): John Wiley & Sons Inc; 2001. 39 Suppl: 20.2:20.2.1–20.2.16
   Google Scholar
• Bolstad BM, Irizarry RA, Astrand M, Speed TP. A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinforma Oxf Engl. 2003;19:185-93. doi:10.1093/bioinformatics/19.2.185
   PubMed Web of Science ®Google Scholar
• Manuel Iglesias J, Beloqui I, Garcia-Garcia F, Leis O, Vazquez-Martin A, Eguiara A, Cufi S, Pavon A, Menendez JA, Dopazo J, et al. Mammosphere formation in breast carcinoma cell lines depends upon expression of E-cadherin. PLoS One. 2013;8:e77281. doi:10.1371/journal.pone.0077281. PMID:24124614
   PubMed Web of Science ®Google Scholar
• Collina F, Di Bonito M, Li Bergolis V, De Laurentiis M, Vitagliano C, Cerrone M, Nuzzo F, Cantile M, Botti G. Prognostic value of cancer stem cells markers in triple-negative breast cancer. BioMed Res Int. 2015;2015:158682. doi:10.1155/2015/158682. PMID:26504780
   PubMed Web of Science ®Google Scholar
• Cao Z, Chen X, Lan L, Zhang Z, Du J, Liao L. Active hexose correlated compound potentiates the antitumor effects of low-dose 5-fluorouracil through modulation of immune function in hepatoma 22 tumor-bearing mice. Nutr Res Pract. 2015;9:129-36. doi:10.4162/nrp.2015.9.2.129. PMID:25861418
   PubMed Web of Science ®Google Scholar
• Matsushita K, Kuramitsu Y, Ohiro Y, Obara M, Kobayashi M, Li YQ, Hosokawa M. Combination therapy of active hexose correlated compound plus UFT significantly reduces the metastasis of rat mammary adenocarcinoma. Anticancer Drugs. 1998;9:343-50. doi:10.1097/00001813-199804000-00008. PMID:9635925
   PubMed Web of Science ®Google Scholar
• Schwarz-Cruz Y Celis A, Espinosa M, Maldonado V, Melendez-Zajgla J. Advances in the knowledge of breast cancer stem cells. A Review Histol Histopathol. 2015;31(6):601–12. doi:10.14670/HH-11-718.
   PubMed Web of Science ®Google Scholar
• Nawata J, Kuramitsu Y, Wang Y, Kitagawa T, Tokuda K, Baron B, Akada J, Suenaga S, Kaino S, Maehara S, et al. Active hexose-correlated compound down-regulates sex-determining region Y-box 2 of pancreatic cancer cells. Anticancer Res. 2014;34:4807-11. PMID:25202061
   PubMed Web of Science ®Google Scholar
• Duru N, Gernapudi R, Eades G, Eckert R, Zhou Q. Epigenetic Regulation of miRNAs and breast cancer stem cells. Curr Pharmacol Rep. 2015;1:161-9. doi:10.1007/s40495-015-0022-1. PMID:26052481
   PubMedGoogle Scholar
• Dent R, Trudeau M, Pritchard KI, Hanna WM, Kahn HK, Sawka CA, Lickley LA, Rawlinson E, Sun P, Narod SA. Triple-negative breast cancer: clinical features and patterns of recurrence. Clin Cancer Res Off J Am Assoc Cancer Res. 2007;13:4429-34. doi:10.1158/1078-0432.CCR-06-3045
   PubMed Web of Science ®Google Scholar
• Martin HL, Smith L, Tomlinson DC. Multidrug-resistant breast cancer: current perspectives. Breast Cancer Targets Ther. 2014;6:1-13.
   PubMedGoogle Scholar
• Boyle P. Triple-negative breast cancer: epidemiological considerations and recommendations. Ann Oncol Off J Eur Soc Med Oncol ESMO. 2012;23 Suppl 6:vi7-12. doi:10.1093/annonc/mds187
   PubMed Web of Science ®Google Scholar
• Paclitaxel (Taxol, Onxal) Chemotherapy Drug Information [ Internet]. [ cited 2016 Apr 3]. Available from: http://chemocare.com/chemotherapy/drug-info/Paclitaxel.aspx
   Google Scholar
• Larzabal L, El-Nikhely N, Redrado M, Seeger W, Savai R, Calvo A. Differential effects of Drugs Targeting Cancer Stem Cell (CSC) and Non-CSC populations on lung primary tumors and metastasis. Plos One. 2013;8:e79798. doi:10.1371/journal.pone.0079798. PMID:24278179
   PubMed Web of Science ®Google Scholar
• Nilsson S, Möller C, Jirström K, Lee A, Busch S, Lamb R, Landberg G. Downregulation of miR-92a is associated with aggressive breast cancer features and increased tumour macrophage infiltration. PloS One. 2012;7:e36051. doi:10.1371/journal.pone.0036051. PMID:22563438
   PubMed Web of Science ®Google Scholar
• Niu J, Xue A, Chi Y, Xue J, Wang W, Zhao Z, et al. Induction of miRNA-181a by genotoxic treatments promotes chemotherapeutic resistance and metastasis in breast cancer. Oncogene. 2015;35(10):1302–1313. doi:10.1038/onc.2015.189.
   PubMed Web of Science ®Google Scholar
• Lowery AJ, Miller N, Dwyer RM, Kerin MJ. Dysregulated miR-183 inhibits migration in breast cancer cells. BMC Cancer. 2010;10:502. doi:10.1186/1471-2407-10-502. PMID:20858276
   PubMed Web of Science ®Google Scholar
• Tomé M, López-Romero P, Albo C, Sepúlveda JC, Fernández-Gutiérrez B, Dopazo A, Bernad A, González MA. miR-335 orchestrates cell proliferation, migration and differentiation in human mesenchymal stem cells. Cell Death Differ. 2011;18:985-95. doi:10.1038/cdd.2010.167. PMID:21164520
   PubMed Web of Science ®Google Scholar
• Wu Z, Li X, Cai X, Huang C, Zheng M. miR-497 inhibits epithelial mesenchymal transition in breast carcinoma by targeting Slug. Tumour Biol J Int Soc Oncodevelopmental Biol Med. 2015;37(6), 7939–50. doi:10.1007/s13277-015-4665-7.
   Google Scholar
• Janssen EAM, Slewa A, Gudlaugsson E, Jonsdottir K, Skaland I, Søiland H, Baak JP. Biologic profiling of lymph node negative breast cancers by means of microRNA expression. Mod Pathol. 2010;23:1567-76. doi:10.1038/modpathol.2010.177. PMID:20818337
   PubMed Web of Science ®Google Scholar
• Li L-Z, Zhang CZ, Liu L-L, Yi C, Lu S-X, Zhou X, Zhang ZJ, Peng YH, Yang YZ, Yun JP. miR-720 inhibits tumor invasion and migration in breast cancer by targeting TWIST1. Carcinogenesis. 2014;35:469-78. doi:10.1093/carcin/bgt330. PMID:24085799
   PubMed Web of Science ®Google Scholar
• Gonul O, Aydin HH, Kalmis E, Kayalar H, Ozkaya AB, Atay S, Ak H. Effects of Ganoderma lucidum (higher basidiomycetes) extracts on the miRNA profile and telomerase activity of the MCF-7 breast cancer cell line. Int J Med Mushrooms. 2015;17:231-9. doi:10.1615/IntJMedMushrooms.v17.i3.30. PMID:25954907
   PubMed Web of Science ®Google Scholar
• Tavazoie SF, Alarcón C, Oskarsson T, Padua D, Wang Q, Bos PD, Gerald WL, Massagué J. Endogenous human microRNAs that suppress breast cancer metastasis. Nature. 2008;451:147-52. doi:10.1038/nature06487. PMID:18185580
   PubMed Web of Science ®Google Scholar
• Tomé M, Sepúlveda JC, Delgado M, Andrades JA, Campisi J, González MA, Bernad A. miR-335 correlates with senescence/aging in human mesenchymal stem cells and inhibits their therapeutic actions through inhibition of AP-1 activity. Stem Cells Dayt. Ohio. 2014;32:2229-44. doi:10.1002/stem.1699
   PubMed Web of Science ®Google Scholar
• Jachetti E, Caputo S, Mazzoleni S, Brambillasca CS, Parigi SM, Grioni M, Piras IS, Restuccia U, Calcinotto A, Freschi M, et al. Tenascin-C protects cancer stem-like cells from immune surveillance by arresting T-cell activation. Cancer Res. 2015;75:2095-108. doi:10.1158/0008-5472.CAN-14-2346. PMID:25808872
   PubMed Web of Science ®Google Scholar
• Chen C, Wu C-Q, Zhang Z-Q, Yao D-K, Zhu L. Loss of expression of miR-335 is implicated in hepatic stellate cell migration and activation. Exp Cell Res. 2011;317:1714-25. doi:10.1016/j.yexcr.2011.05.001. PMID:21586285
   PubMed Web of Science ®Google Scholar
• Vuong T, Matar C, Ramassamy C, Haddad PS. Biotransformed blueberry juice protects neurons from hydrogen peroxide-induced oxidative stress and mitogen-activated protein kinase pathway alterations. Br J Nutr. 2010;104:656-63. doi:10.1017/S0007114510001170. PMID:20459875
   PubMed Web of Science ®Google Scholar
• Aviles H, O'Donnell P, Orshal J, Fujii H, Sun B, Sonnenfeld G. Active hexose correlated compound activates immune function to decrease bacterial load in a murine model of intramuscular infection. Am J Surg. 2008;195:537-45. doi:10.1016/j.amjsurg.2007.05.045. PMID:18304499
   PubMed Web of Science ®Google Scholar
• Aviles H, Belay T, Fountain K, Vance M, Sun B, Sonnenfeld G. Active hexose correlated compound enhances resistance to Klebsiella pneumoniae infection in mice in the hindlimb-unloading model of spaceflight conditions. J Appl Physiol Bethesda Md 1985. 2003;95:491-6.
   PubMed Web of Science ®Google Scholar
• Fujii H, Nishioka N, Simon RR, Kaur R, Lynch B, Roberts A. Genotoxicity and subchronic toxicity evaluation of Active Hexose Correlated Compound (AHCC). Regul Toxicol Pharmacol. 2011;59:237-50. doi:10.1016/j.yrtph.2010.10.006. PMID:20951179
   PubMed Web of Science ®Google Scholar
• Nagakawa H, Shimozato O, Yu L, Takiguchi Y, Tatsumi K, Kuriyama T, Tagawa M. Expression of interleukin-22 in murine carcinoma cells did not influence tumour growth in vivo but did improve survival of the inoculated hosts. Scand J Immunol. 2004;60:449-54. doi:10.1111/j.0300-9475.2004.01504.x. PMID:15541036
   PubMed Web of Science ®Google Scholar