Exosome-transmitted circular RNA circ-LMO7 facilitates the progression of osteosarcoma by regulating miR-21-5p/ARHGAP24 axis

References

• Luetke A, Meyers PA, Lewis I, Juergens H. Osteosarcoma treatment – where do we stand? A state of the art review. Cancer Treat Rev. 2014;40(4):523–11. doi:10.1016/j.ctrv.2013.11.006.
   PubMed Web of Science ®Google Scholar
• Kager L, Tamamyan G, Bielack S. Novel insights and therapeutic interventions for pediatric osteosarcoma. Future Oncol. 2017;13(4):357–368. doi:10.2217/fon-2016-0261.
   PubMed Web of Science ®Google Scholar
• Meazza C, Scanagatta P. Metastatic osteosarcoma: a challenging multidisciplinary treatment. Expert Rev Anticancer Ther. 2016;16(5):543–556. doi:10.1586/14737140.2016.1168697.
   PubMed Web of Science ®Google Scholar
• Belayneh R, Fourman MS, Bhogal S, Weiss KR. Update on Osteosarcoma. Curr Oncol Rep. 2021;23(6):71. doi:10.1007/s11912-021-01053-7.
   PubMed Web of Science ®Google Scholar
• Anderson ME. Update on Survival in Osteosarcoma. Orthop Clin North Am. 2016;47(1):283–292. doi:10.1016/j.ocl.2015.08.022.
   PubMed Web of Science ®Google Scholar
• Zhu X, Li S. Nanomaterials in tumor immunotherapy: new strategies and challenges. Mol Cancer. 2023;22(1):94. doi:10.1186/s12943-023-01797-9.
   PubMed Web of Science ®Google Scholar
• Gao X, Gao B, Li S. Extracellular vesicles: a new diagnostic biomarker and targeted drug in osteosarcoma. Front Immunol. 2022;13:1002742. doi:10.3389/fimmu.2022.1002742.
   PubMed Web of Science ®Google Scholar
• Chen LL. The expanding regulatory mechanisms and cellular functions of circular RNAs. Nat Rev Mol Cell Biol. 2020;21(8):475–490. doi:10.1038/s41580-020-0243-y.
   PubMed Web of Science ®Google Scholar
• Zhang J, Liu H, Zhao P, Zhou H, Mao T. Has_circ_0055625 from circRNA profile increases colon cancer cell growth by sponging miR-106b-5p. J Cell Biochem. 2019; 120(3):3027–3037. doi:10.1002/jcb.27355.
   PubMed Web of Science ®Google Scholar
• Li J, Li Z, Jiang P, Peng M, Zhang X, Chen K, Liu H, Bi H, Liu X, Li X, et al. Circular RNA IARS (circ-IARS) secreted by pancreatic cancer cells and located within exosomes regulates endothelial monolayer permeability to promote tumor metastasis. J Exp Clin Cancer Res. 2018; 37(1):177. doi:10.1186/s13046-018-0822-3.
   PubMed Web of Science ®Google Scholar
• Sang Y, Chen B, Song X, Li Y, Liang Y, Han D, Zhang N, Zhang H, Liu Y, Chen T, et al. circRNA_0025202 regulates tamoxifen sensitivity and tumor progression via regulating the miR-182-5p/FOXO3a axis in breast cancer. Mol Ther. 2019; 27(9):1638–1652. doi:10.1016/j.ymthe.2019.05.011.
   PubMed Web of Science ®Google Scholar
• Wang X, Xing L, Yang R, Chen H, Wang M, Jiang R, Zhang L, Chen J. The circACTN4 interacts with FUBP1 to promote tumorigenesis and progression of breast cancer by regulating the expression of proto-oncogene MYC. Mol Cancer. 2021;20(1):91. doi:10.1186/s12943-021-01383-x.
   PubMed Web of Science ®Google Scholar
• Li S, Liu F, Zheng K, Wang W, Qiu E, Pei Y, Wang S, Zhang J, Zhang X. CircDOCK1 promotes the tumorigenesis and cisplatin resistance of osteogenic sarcoma via the miR-339-3p/IGF1R axis. Mol Cancer. 2021;20(1):161. doi:10.1186/s12943-021-01453-0.
   PubMed Web of Science ®Google Scholar
• Chen Y, Yang F, Fang E, Xiao W, Mei H, Li H, Li D, Song H, Wang J, Hong M, et al. Circular RNA circAGO2 drives cancer progression through facilitating HuR-repressed functions of AGO2-miRNA complexes. Cell Death Differ. 2019; 26(7):1346–1364. doi:10.1038/s41418-018-0220-6.
   PubMed Web of Science ®Google Scholar
• Zhang Q, Zhang C, Ma JX, Ren H, Sun Y, Xu JZ. Circular RNA PIP5K1A promotes colon cancer development through inhibiting miR-1273a. World J Gastroenterol. 2019; 25(35):5300–5309. doi:10.3748/wjg.v25.i35.5300.
   PubMed Web of Science ®Google Scholar
• Ma C, Wang X, Yang F, Zang Y, Liu J, Wang X, Xu X, Li W, Jia J, Liu Z, et al. Circular RNA hsa_circ_0004872 inhibits gastric cancer progression via the miR-224/Smad4/ADAR1 successive regulatory circuit. Mol Cancer. 2020; 19(1):157. doi:10.1186/s12943-020-01268-5.
   PubMed Web of Science ®Google Scholar
• Dweep H, Gretz N, Sticht C. miRwalk database for miRNA-target interactions. Methods Mol Biol. 2014;1182:289–305.
   PubMedGoogle Scholar
• Han M, Hu J, Lu P, Cao H, Yu C, Li X, Qian X, Yang X, Yang Y, Han N, et al. RETRACTED ARTICLE: exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer. Cell Death Disease. 2020; 11(1):43. doi:10.1038/s41419-020-2250-5.
   PubMed Web of Science ®Google Scholar
• Kristensen LS, Jakobsen T, Hager H, Kjems J. The emerging roles of circRnas in cancer and oncology. Nat Rev Clin Oncol. 2022;19(3):188–206. doi:10.1038/s41571-021-00585-y.
   PubMed Web of Science ®Google Scholar
• Papatsirou M, Artemaki PI, Karousi P, Scorilas A, Kontos CK. Circular RNAs: emerging regulators of the major signaling pathways involved in cancer progression. Cancers (Basel). 2021;13(11):2744. doi:10.3390/cancers13112744.
   PubMed Web of Science ®Google Scholar
• Xue C, Li G, Lu J, Li L. Crosstalk between circRnas and the PI3K/AKT signaling pathway in cancer progression. Sig Transduct Target Ther. 2021;6(1):400. doi:10.1038/s41392-021-00788-w.
   PubMed Web of Science ®Google Scholar
• Li Z, Li X, Xu D, Chen X, Li S, Zhang L, Chan MT, Wu WK. An update on the roles of circular RNAs in osteosarcoma. Cell Prolif. 2021; 54(1):e12936. doi:10.1111/cpr.12936.
   PubMed Web of Science ®Google Scholar
• Shen S, Yao T, Xu Y, Zhang D, Fan S, Ma J. CircECE1 activates energy metabolism in osteosarcoma by stabilizing c-Myc. Mol Cancer. 2020;19(1):151. doi:10.1186/s12943-020-01269-4.
   PubMed Web of Science ®Google Scholar
• Liu Y, Qiu G, Luo Y, Li S, Xu Y, Zhang Y, Hu J, Li P, Pan H, Wang Y, et al. Circular RNA ROCK1, a novel circRNA, suppresses osteosarcoma proliferation and migration via altering the miR-532-5p/PTEN axis. Exp mol med. 2022; 54(7):1024–1037. doi:10.1038/s12276-022-00806-z.
   PubMed Web of Science ®Google Scholar
• Yang B, Li L, Tong G, Zeng Z, Tan J, Su Z, Liu Z, Lin J, Gao W, Chen J, et al. Circular RNA circ_001422 promotes the progression and metastasis of osteosarcoma via the miR-195-5p/FGF2/PI3K/Akt axis. J Exp Clin Cancer Res. 2021; 40(1):235. doi:10.1186/s13046-021-02027-0.
   PubMed Web of Science ®Google Scholar
• Wang L, Wei W-Q, Wu Z-Y, Wang G-C. MicroRNA-590-5p regulates cell viability, apoptosis, migration and invasion of renal cell carcinoma cell lines through targeting ARHGAP24. Mol BioSyst. 2017;13(12):2564–2573. doi:10.1039/C7MB00406K.
   PubMedGoogle Scholar
• Xu G, Lu X, Huang T, Fan J. ARHGAP24 inhibits cell cycle progression, induces apoptosis and suppresses invasion in renal cell carcinoma. Oncotarget. 2016;7(32):51829–51839. doi:10.18632/oncotarget.10386.
   PubMedGoogle Scholar
• Xie H, Yao J, Wang Y, Ni B. Exosome-transmitted circVMP1 facilitates the progression and cisplatin resistance of non-small cell lung cancer by targeting miR-524-5p-METTL3/SOX2 axis. Drug Deliv. 2022; 29(1):1257–1271. doi:10.1080/10717544.2022.2057617.
   PubMed Web of Science ®Google Scholar
• Chen W, Quan Y, Fan S, Wang H, Liang J, Huang L, Chen L, Liu Q, He P, Ye Y, et al. Exosome-transmitted circular RNA hsa_circ_0051443 suppresses hepatocellular carcinoma progression. Cancer Lett. 2020;475:119–128. doi:10.1016/j.canlet.2020.01.022.
   PubMed Web of Science ®Google Scholar
• Guo X, Gao C, Yang DH, Li S. Exosomal circular RNAs: a chief culprit in cancer chemotherapy resistance. Drug Resist Updat. 2023;67:100937. doi:10.1016/j.drup.2023.100937.
   PubMed Web of Science ®Google Scholar
• Li S. The basic characteristics of extracellular vesicles and their potential application in bone sarcomas. J Nanobiotechnology. 2021;19(1):277. doi:10.1186/s12951-021-01028-7.
   PubMed Web of Science ®Google Scholar
• Yue J, Chen Z-S, Xu X-X, Li S. Functions and therapeutic potentials of exosomes in osteosarcoma. Acta Mater Med. 2022;1(4):552–562. doi:10.15212/AMM-2022-0024.
   PubMedGoogle Scholar