Cancer Biology & Therapy, Volume 25, Issue 1 (2024)

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Cancer Biology & Therapy, Volume 25, Issue 1 (2024)

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Research Paper

Article
Red ginseng polysaccharide promotes ferroptosis in gastric cancer cells by inhibiting PI3K/Akt pathway through down-regulation of AQP3
Yan Wang, Wen-Xian Guan, Yuan Zhou, Xiao-Yu Zhang & Hai-Jian Zhao
Article: 2284849
Published online: 05 Dec 2023
AbstractforRed ginseng polysaccharide promotes ferroptosis in gastric cancer cells by inhibiting PI3K/Akt pathway through down-regulation of AQP3 | Full Text | References | PDF (5.6 MB) | EPUB
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Article
Diagnostic value of 18F-PSMA-1007 PET/CT for predicting the pathological grade of prostate cancer
Xiao-Bo Niu, Yan-Peng Li, Jun Wang, Xiao-Li Mei, Xue-Yan Zhao, Ting-Ting Liu, Sha-Sha Xu, Xing-Min Han & Jing-Liang Cheng
Article: 2287120
Published online: 20 Dec 2023
AbstractforDiagnostic value of 18F-PSMA-1007 PET/CT for predicting the pathological grade of prostate cancer | Full Text | References | PDF (2 MB) | EPUB
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Article
Chaperonin containing TCP1 subunit 6A may activate Notch and Wnt pathways to facilitate the malignant behaviors and cancer stemness in oral squamous cell carcinoma
Yangyi Chen, Yongge Chen & Weixian Liu
Article: 2287122
Published online: 12 Dec 2023
AbstractforChaperonin containing TCP1 subunit 6A may activate Notch and Wnt pathways to facilitate the malignant behaviors and cancer stemness in oral squamous cell carcinoma | Full Text | References | PDF (5.8 MB) | EPUB | Supplemental
  • 2242 Views
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Article
Tumor-derived exosomal miR-1247-3p promotes angiogenesis in bladder cancer by targeting FOXO1
Zonglai Liu, Dan Du & Shizhong Zhang
Article: 2290033
Published online: 10 Dec 2023
AbstractforTumor-derived exosomal miR-1247-3p promotes angiogenesis in bladder cancer by targeting FOXO1 | Full Text | References | PDF (3.8 MB) | EPUB | Supplemental
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Article
Elucidating structural variability in p53 conformers using combinatorial refinement strategies and molecular dynamics
Deborah F. Kelly, Maria J. Solares & William J. Dearnaley
Article: 2290732
Published online: 10 Dec 2023
AbstractforElucidating structural variability in p53 conformers using combinatorial refinement strategies and molecular dynamics | Full Text | References | PDF (7.5 MB) | EPUB | Supplemental
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Research paper

Article
The amino acid transporter SLC7A11 expression in breast cancer
Preyanka Nath, Lutfi H. Alfarsi, Rokaya El-Ansari, Brendah K. Masisi, Busra Erkan, Ali Fakroun, Ian O. Ellis, Emad A. Rakha & Andrew R. Green
Article: 2291855
Published online: 10 Dec 2023
AbstractforThe amino acid transporter SLC7A11 expression in breast cancer | Full Text | References | PDF (2.2 MB) | EPUB | Supplemental
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Research Paper

Article
Efficacy and pharmacodynamic effect of anti-CD73 and anti-PD-L1 monoclonal antibodies in combination with cytotoxic therapy: observations from mouse tumor models
Brajesh P. Kaistha, Gozde Kar, Andreas Dannhorn, Amanda Watkins, Grace Opoku-Ansah, Kristina Ilieva, Stefanie Mullins, Judith Anderton, Elena Galvani, Fabien Garcon, Jean-Martin Lapointe, Lee Brown, James Hair, Tim Slidel, Nadia Luheshi, Kelli Ryan, Elizabeth Hardaker, Simon Dovedi, Rakesh Kumar, Robert W. Wilkinson, Scott A. Hammond & Jim Eyles
Article: 2296048
Published online: 11 Jan 2024
AbstractforEfficacy and pharmacodynamic effect of anti-CD73 and anti-PD-L1 monoclonal antibodies in combination with cytotoxic therapy: observations from mouse tumor models | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
  • 3883 Views
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Article
WYC-209 inhibited GC malignant progression by down-regulating WNT4 through RARα
Zhenyuan Qian, Wenfa Lin, Xufan Cai, Jianzhang Wu, Kun Ke, Zaiyuan Ye & Fang Wu
Article: 2299288
Published online: 04 Jan 2024
AbstractforWYC-209 inhibited GC malignant progression by down-regulating WNT4 through RARα | Full Text | References | PDF (5.2 MB) | EPUB
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Correction

Correction
Correction
Article: 2299054
Published online: 26 Dec 2023
CitationforCorrection | Full Text | PDF (898.7 KB) | EPUB
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Review

Review Article
The critical role of tumor microbiome in cancer immunotherapy
Liu Yang, Qi Wang, Lijuan He & Xingyu Sun
Article: 2301801
Published online: 19 Jan 2024
AbstractforThe critical role of tumor microbiome in cancer immunotherapy | Full Text | References | PDF (1 MB) | EPUB
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Research Paper

Article
Mutually exclusive teams-like patterns of gene regulation characterize phenotypic heterogeneity along the noradrenergic-mesenchymal axis in neuroblastoma
Manas Sehgal, Sonali Priyadarshini Nayak, Sarthak Sahoo, Jason A Somarelli & Mohit Kumar Jolly
Article: 2301802
Published online: 17 Jan 2024
AbstractforMutually exclusive teams-like patterns of gene regulation characterize phenotypic heterogeneity along the noradrenergic-mesenchymal axis in neuroblastoma | Full Text | References | PDF (5.4 MB) | EPUB | Supplemental
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Article
The facilitating effects of KRT80 on chemoresistance, lipogenesis, and invasion of esophageal cancer
Wen-Jing Yun, Jun Li, Nan-Chang Yin, Cong-Yu Zhang, Zheng-Guo Cui, Li Zhang & Hua-Chuan Zheng
Article: 2302162
Published online: 19 Jan 2024
AbstractforThe facilitating effects of KRT80 on chemoresistance, lipogenesis, and invasion of esophageal cancer | Full Text | References | PDF (4.3 MB) | EPUB | Supplemental
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Article
The antipsychotic drug pimozide promotes apoptosis through the RAF/ERK pathway and enhances autophagy in breast cancer cells
Ge Jiang, Xingzhi Zhou, Ye Hu, Xiaoyu Tan, Dan Wang, Lina Yang, Qinggao Zhang & Shuangping Liu
Article: 2302413
Published online: 14 Feb 2024
AbstractforThe antipsychotic drug pimozide promotes apoptosis through the RAF/ERK pathway and enhances autophagy in breast cancer cells | Full Text | References | PDF (9.5 MB) | EPUB | Supplemental
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Article
Epigenetic silencing ZSCAN23 promotes pancreatic cancer growth by activating Wnt signaling
Qian Du, Meiying Zhang, Aiai Gao, Tao He & Mingzhou Guo
Article: 2302924
Published online: 16 Jan 2024
AbstractforEpigenetic silencing ZSCAN23 promotes pancreatic cancer growth by activating Wnt signaling | Full Text | References | PDF (6.1 MB) | EPUB | Supplemental
  • 2260 Views
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Article
Hypoxia promotes non-small cell lung cancer cell stemness, migration, and invasion via promoting glycolysis by lactylation of SOX9
Fei Yan, Yue Teng, Xiaoyou Li, Yuejiao Zhong, Chunyi Li, Feng Yan & Xia He
Article: 2304161
Published online: 16 Jan 2024
AbstractforHypoxia promotes non-small cell lung cancer cell stemness, migration, and invasion via promoting glycolysis by lactylation of SOX9 | Full Text | References | PDF (5.3 MB) | EPUB
  • 3669 Views
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Article
M6A modification regulates tumor suppressor DIRAS1 expression in cervical cancer cells
Yu-Yan Wang, Lian-Hua Ye, An-Qi Zhao, Wei-Ran Gao, Ning Dai, Yu Yin & Xin Zhang
Article: 2306674
Published online: 19 Feb 2024
AbstractforM6A modification regulates tumor suppressor DIRAS1 expression in cervical cancer cells | Full Text | References | PDF (5.2 MB) | EPUB
  • 1938 Views
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Review

Review Article
Fusobacterium nucleatum in tumors: from tumorigenesis to tumor metastasis and tumor resistance
Chun Ye, Xiao Liu, Zilun Liu, Chuxuan Pan, Xiaowei Zhang, Zhanyi Zhao & Haitao Sun
Article: 2306676
Published online: 30 Jan 2024
AbstractforFusobacterium nucleatum in tumors: from tumorigenesis to tumor metastasis and tumor resistance | Full Text | References | PDF (5.3 MB) | EPUB
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Review Article
A landscape of checkpoint blockade resistance in cancer: underlying mechanisms and current strategies to overcome resistance
Ginette S. Santiago-Sánchez, Kellsye P. Fabian & James W. Hodge
Article: 2308097
Published online: 02 Feb 2024
AbstractforA landscape of checkpoint blockade resistance in cancer: underlying mechanisms and current strategies to overcome resistance | Full Text | References | PDF (2.6 MB) | EPUB
  • 2137 Views
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Research Paper

Article
MiR-378a-5p exerts a radiosensitizing effect on CRC through LRP8/β-catenin axis
Guolin Hu, Pengbiao Che, Ling Deng, Lei Liu, Jia Liao & Qi Liu
Article: 2308165
Published online: 22 Feb 2024
AbstractforMiR-378a-5p exerts a radiosensitizing effect on CRC through LRP8/β-catenin axis | Full Text | References | PDF (6.8 MB) | EPUB
  • 2106 Views
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Article
Influence of genetic polymorphisms in vascular endothelial-related genes on the clinical outcome of axitinib in patients with metastatic renal cell carcinoma
Kazuyuki Numakura, Ryoma Igarashi, Makoto Takahashi, Taketoshi Nara, Sohei Kanda, Mitsuru Saito, Shintaro Narita, Takamitsu Inoue, Takenori Niioka, Masatomo Miura & Tomonori Habuchi
Article: 2312602
Published online: 07 Feb 2024
AbstractforInfluence of genetic polymorphisms in vascular endothelial-related genes on the clinical outcome of axitinib in patients with metastatic renal cell carcinoma | Full Text | References | PDF (356.2 KB) | EPUB
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Article
CD46 and CD59 inhibitors enhance complement-dependent cytotoxicity of anti-CD38 monoclonal antibodies daratumumab and isatuximab in multiple myeloma and other B-cell malignancy cells
Hongjie Wang, Theo Koob, Jonathan R. Fromm, Ajay Gopal, Darrick Carter & André Lieber
Article: 2314322
Published online: 15 Feb 2024
AbstractforCD46 and CD59 inhibitors enhance complement-dependent cytotoxicity of anti-CD38 monoclonal antibodies daratumumab and isatuximab in multiple myeloma and other B-cell malignancy cells | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
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Article
MDFI promotes the proliferation and tolerance to chemotherapy of colorectal cancer cells by binding ITGB4/LAMB3 to activate the AKT signaling pathway
Ding Ma, Shuwen Liu, Kua Liu, Lingkai Kong, Lingjun Xiao, Qilei Xin, Chunping Jiang & Junhua Wu
Article: 2314324
Published online: 20 Feb 2024
AbstractforMDFI promotes the proliferation and tolerance to chemotherapy of colorectal cancer cells by binding ITGB4/LAMB3 to activate the AKT signaling pathway | Full Text | References | PDF (6.6 MB) | EPUB | Supplemental
  • 2567 Views
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Article
miR-10b-5p promotes tumor growth by regulating cell metabolism in liver cancer via targeting SLC38A2
Mingzhi Xia, Jie Chen, Yingyun Hu, Bin Qu, Qianqian Bu & Haoming Shen
Article: 2315651
Published online: 23 Feb 2024
AbstractformiR-10b-5p promotes tumor growth by regulating cell metabolism in liver cancer via targeting SLC38A2 | Full Text | References | PDF (10.1 MB) | EPUB | Supplemental
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Review

Review Article
Immunotherapy resistance in solid tumors: mechanisms and potential solutions
Daniel S. Lefler, Steven A. Manobianco & Babar Bashir
Article: 2315655
Published online: 22 Feb 2024
AbstractforImmunotherapy resistance in solid tumors: mechanisms and potential solutions | Full Text | References | PDF (1 MB) | EPUB
  • 2193 Views
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Review Article
Understanding the molecular mechanism responsible for developing therapeutic radiation-induced radioresistance of rectal cancer and improving the clinical outcomes of radiotherapy - A review
Samatha M Jain, Shruthi Nagainallur Ravichandran, Makalakshmi Murali Kumar, Antara Banerjee, Alexander Sun-Zhang, Hong Zhang, Rupak Pathak, Xiao-Feng Sun & Surajit Pathak
Article: 2317999
Published online: 06 Mar 2024
AbstractforUnderstanding the molecular mechanism responsible for developing therapeutic radiation-induced radioresistance of rectal cancer and improving the clinical outcomes of radiotherapy - A review | Full Text | References | PDF (3.6 MB) | EPUB
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Correction

Correction
Correction
Article: 2318833
Published online: 13 Feb 2024
CitationforCorrection | Full Text | PDF (170.4 KB) | EPUB
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Research Paper

Article
SATB1 mediated tumor colonization and β-catenin nuclear localization are associated with colorectal cancer progression
Luan Sun, Feng Wang, Xufei Wang, Feiying Zhang, Sujuan Ma & Jinghuan Lv
Article: 2320307
Published online: 22 Feb 2024
AbstractforSATB1 mediated tumor colonization and β-catenin nuclear localization are associated with colorectal cancer progression | Full Text | References | PDF (5.8 MB) | EPUB | Supplemental
  • 1920 Views
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Article
Role of glutaminyl-peptide cyclotransferase in breast cancer doxorubicin sensitivity
Bin Xu, Liu Yang, Lixian Yang, Ahmed Al-Maamari, Jingyu Zhang, Heng Song, Meiqi Wang, Suwen Su & Zhenchuan Song
Article: 2321767
Published online: 28 Feb 2024
AbstractforRole of glutaminyl-peptide cyclotransferase in breast cancer doxorubicin sensitivity | Full Text | References | PDF (6.2 MB) | EPUB | Supplemental
  • 2568 Views
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Review

Review Article
The role of liver cancer stem cells in hepatocellular carcinoma metastasis
Qinghui Niu, Susu Ye, Liu Zhao, Yanzhi Qian & Fengchao Liu
Article: 2321768
Published online: 23 Feb 2024
AbstractforThe role of liver cancer stem cells in hepatocellular carcinoma metastasis | Full Text | References | PDF (1.5 MB) | EPUB
  • 2772 Views
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Research Paper

Article
A mathematical model for predicting the spatiotemporal response of breast cancer cells treated with doxorubicin
Hugo J. M. Miniere, Ernesto A. B. F. Lima, Guillermo Lorenzo, David A. Hormuth II, Sophia Ty, Amy Brock & Thomas E. Yankeelov
Article: 2321769
Published online: 27 Feb 2024
AbstractforA mathematical model for predicting the spatiotemporal response of breast cancer cells treated with doxorubicin | Full Text | References | PDF (9.6 MB) | EPUB | Supplemental
  • 2692 Views
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Article
RND1 inhibits epithelial-mesenchymal transition and temozolomide resistance of glioblastoma via AKT/GSK3-β pathway
Qian Sun, Junjie Xu, Fan’en Yuan, Yan Liu, Qianxue Chen, Lirui Guo, Huimin Dong & Baohui Liu
Article: 2321770
Published online: 05 Mar 2024
AbstractforRND1 inhibits epithelial-mesenchymal transition and temozolomide resistance of glioblastoma via AKT/GSK3-β pathway | Full Text | References | PDF (5 MB) | EPUB | Supplemental
  • 2288 Views
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Article
Salidroside inhibited the proliferation of gastric cancer cells through up-regulating tumor suppressor miR-1343-3p and down-regulating MAP3K6/MMP24 signal molecules
Xiaoping Wang, Zhendong Zhang & Xiaolan Cao
Article: 2322206
Published online: 04 Mar 2024
AbstractforSalidroside inhibited the proliferation of gastric cancer cells through up-regulating tumor suppressor miR-1343-3p and down-regulating MAP3K6/MMP24 signal molecules | Full Text | References | PDF (3.9 MB) | EPUB
  • 2238 Views
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Article
The relationship between long non-coding gene CASC21 polymorphisms and cervical cancer
Lili Han, Jing Liu, Mireayi Shataer, Chengyong Wu & Mayinuer Niyazi
Article: 2322207
Published online: 11 Mar 2024
AbstractforThe relationship between long non-coding gene CASC21 polymorphisms and cervical cancer | Full Text | References | PDF (734.7 KB) | EPUB | Supplemental
  • 1309 Views
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Article
Dynamic evolution of bone marrow adipocyte in B cell acute lymphoblastic leukemia: insights from diagnosis to post-chemotherapy
Xi Jia, Naying Liao, Yunqian Yao, Xutao Guo, Kai Chen & Pengcheng Shi
Article: 2323765
Published online: 11 Mar 2024
AbstractforDynamic evolution of bone marrow adipocyte in B cell acute lymphoblastic leukemia: insights from diagnosis to post-chemotherapy | Full Text | References | PDF (4.1 MB) | EPUB | Supplemental
  • 1731 Views
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Article
Repression of the SUMO-conjugating enzyme UBC9 is associated with lowered double minutes and reduced tumor progression
Yusi Wang, Hongyan Zou, Wei Ji, Min Huang, Benhui You, Nan Sun, Yuandong Qiao, Peng Liu, Lidan Xu, Xuelong Zhang, Mengdi Cai, Ye Kuang, Songbin Fu, Wenjing Sun, Xueyuan Jia & Jie Wu
Article: 2323768
Published online: 11 Mar 2024
AbstractforRepression of the SUMO-conjugating enzyme UBC9 is associated with lowered double minutes and reduced tumor progression | Full Text | References | PDF (3.1 MB) | EPUB | Supplemental
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Article
TOP2A modulates signaling via the AKT/mTOR pathway to promote ovarian cancer cell proliferation
Kaiwen Zhang, Xingyu Zheng, Yiqing Sun, Xinyu Feng, Xirong Wu, Wenlu Liu, Chao Gao, Ye Yan, Wenyan Tian & Yingmei Wang
Article: 2325126
Published online: 06 Mar 2024
AbstractforTOP2A modulates signaling via the AKT/mTOR pathway to promote ovarian cancer cell proliferation | Full Text | References | PDF (7.9 MB) | EPUB | Supplemental
  • 2257 Views
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Article
Linoleic acid exhibits anti-proliferative and anti-invasive activities in endometrial cancer cells and a transgenic model of endometrial cancer
Jianqing Qiu, Ziyi Zhao, Hongyan Suo, Sarah E. Paraghamian, Gabrielle M. Hawkins, Wenchuan Sun, Xin Zhang, Tianran Hao, Beor Deng, Xiaochang Shen, Chunxiao Zhou & Victoria Bae-Jump
Article: 2325130
Published online: 11 Mar 2024
AbstractforLinoleic acid exhibits anti-proliferative and anti-invasive activities in endometrial cancer cells and a transgenic model of endometrial cancer | Full Text | References | PDF (4.2 MB) | EPUB
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Article
Role and mechanism of COL3A1 in regulating the growth, metastasis, and drug sensitivity in cisplatin-resistant non-small cell lung cancer cells
Jiankun Ren, Songwei Zhao & Junyu Lai
Article: 2328382
Published online: 26 Mar 2024
AbstractforRole and mechanism of COL3A1 in regulating the growth, metastasis, and drug sensitivity in cisplatin-resistant non-small cell lung cancer cells | Full Text | References | PDF (4.5 MB) | EPUB | Supplemental
  • 2109 Views
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Article
Association between the apoptotic effect of Cabazitaxel and its pro-oxidant efficacy on the redox adaptation mechanisms in prostate cancer cells with different resistance phenotypes
Isil Ezgi Eryilmaz, Unal Egeli & Gulsah Cecener
Article: 2329368
Published online: 14 Mar 2024
AbstractforAssociation between the apoptotic effect of Cabazitaxel and its pro-oxidant efficacy on the redox adaptation mechanisms in prostate cancer cells with different resistance phenotypes | Full Text | References | PDF (7.1 MB) | EPUB
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Article
CPT1A mediates the succinylation of SP5 which activates transcription of PDPK1 to promote the viability and glycolysis of prostate cancer cells
Shufeng Liu, Xiaoguang Chen, Liqi Zhang & Bo Lu
Article: 2329372
Published online: 17 Mar 2024
AbstractforCPT1A mediates the succinylation of SP5 which activates transcription of PDPK1 to promote the viability and glycolysis of prostate cancer cells | Full Text | References | PDF (17.8 MB) | EPUB
  • 1614 Views
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Article
Prognostic value of pretreatment procalcitonin and neutrophil–lymphocyte ratio in extensive-stage small-cell lung cancer
Dongfang Chen, Jianlin Xu, Yizhuo Zhao, Baohui Han & Runbo Zhong
Article: 2331273
Published online: 27 Mar 2024
AbstractforPrognostic value of pretreatment procalcitonin and neutrophil–lymphocyte ratio in extensive-stage small-cell lung cancer | Full Text | References | PDF (959.6 KB) | EPUB
  • 1597 Views
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Article
The effects of Aurora Kinase inhibition on thyroid cancer growth and sensitivity to MAPK-directed therapies
Hannah M. Hicks, Veronica L. Nassar, Jane Lund, Madison M. Rose & Rebecca E. Schweppe
Article: 2332000
Published online: 23 Mar 2024
AbstractforThe effects of Aurora Kinase inhibition on thyroid cancer growth and sensitivity to MAPK-directed therapies | Full Text | References | PDF (3.5 MB) | EPUB | Supplemental
  • 1633 Views
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Article
M6A-mediated molecular patterns and tumor microenvironment infiltration characterization in nasopharyngeal carcinoma
Yong Wang, Lisha Peng & Feng Wang
Article: 2333590
Published online: 26 Mar 2024
AbstractforM6A-mediated molecular patterns and tumor microenvironment infiltration characterization in nasopharyngeal carcinoma | Full Text | References | PDF (8.8 MB) | EPUB | Supplemental
  • 1927 Views
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Article
NRSN2 promotes the malignant behavior of HPV-transfected laryngeal carcinoma cells through AMPK/ULK1 pathway mediated autophagy activation
Fan Guo, Wulin Wen, Zhipeng Mi, Chao Long, Qiangyou Shi, Meihua Yang, Jia Zhao & Ruixia Ma
Article: 2334463
Published online: 03 Apr 2024
AbstractforNRSN2 promotes the malignant behavior of HPV-transfected laryngeal carcinoma cells through AMPK/ULK1 pathway mediated autophagy activation | Full Text | References | PDF (2.9 MB) | EPUB
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Report

Report
Significant response to pembrolizumab plus lenvatinib in Epstein–Barr-virus-associated intrahepatic cholangiocarcinoma: a case report
Lisha Li, Dandan Yu, Jinru Yang, Fangyuan Zhang, Dejun Zhang, Zhenyu Lin, Menglan Zhai, Jing Wang, Tao Zhang & Lei Zhao
Article: 2338644
Published online: 22 Apr 2024
AbstractforSignificant response to pembrolizumab plus lenvatinib in Epstein–Barr-virus-associated intrahepatic cholangiocarcinoma: a case report | Full Text | References | PDF (1.3 MB) | EPUB
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Review

Review Article
Roles of TRPM channels in glioma
Zhigang Chen, Han Xie, Jun Liu, JiaJia Zhao, Ruixiang Huang, Yufei Xiang, Haoyuan Wu, Dasheng Tian, Erbao Bian & Zhang Xiong
Article: 2338955
Published online: 29 Apr 2024
AbstractforRoles of TRPM channels in glioma | Full Text | References | PDF (2.2 MB) | EPUB
  • 1821 Views
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Review Article
Understanding and overcoming resistance to immunotherapy in genitourinary cancers
Sean T Evans, Yash Jani, Caroline S Jansen, Ahmet Yildirim, Ecem Kalemoglu & Mehmet Asim Bilen
Article: 2342599
Published online: 17 Apr 2024
AbstractforUnderstanding and overcoming resistance to immunotherapy in genitourinary cancers | Full Text | References | PDF (1.7 MB) | EPUB
  • 3046 Views
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Research Paper

Article
Exosome-transmitted circular RNA circ-LMO7 facilitates the progression of osteosarcoma by regulating miR-21-5p/ARHGAP24 axis
Anyu Luo, Hanlin Liu, Chen Huang & Sheng Wei
Article: 2343450
Published online: 14 May 2024
AbstractforExosome-transmitted circular RNA circ-LMO7 facilitates the progression of osteosarcoma by regulating miR-21-5p/ARHGAP24 axis | Full Text | References | PDF (4.2 MB) | EPUB
  • 1060 Views
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Review

Review Article
Agent-based modeling in cancer biomedicine: applications and tools for calibration and validation
Nicolò Cogno, Cristian Axenie, Roman Bauer & Vasileios Vavourakis
Article: 2344600
Published online: 28 Apr 2024
AbstractforAgent-based modeling in cancer biomedicine: applications and tools for calibration and validation | Full Text | References | PDF (3.6 MB) | EPUB
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Research Paper

Article
MOICS, a novel classier deciphering immune heterogeneity and aid precise management of clear cell renal cell carcinoma at multiomics level
Ying Liu, Lin Qi, Bicheng Ye, Anbang Wang, Juan Lu, Le Qu, Peng Luo, Linhui Wang & Aimin Jiang
Article: 2345977
Published online: 24 Apr 2024
AbstractforMOICS, a novel classier deciphering immune heterogeneity and aid precise management of clear cell renal cell carcinoma at multiomics level | Full Text | References | PDF (10.4 MB) | EPUB | Supplemental
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Article
METTL14 decreases FTH1 mRNA stability via m6A methylation to promote sorafenib-induced ferroptosis of cervical cancer
Lijie Li, Jie Zeng, Sili He, Yanfei Yang & Chen Wang
Article: 2349429
Published online: 13 May 2024
AbstractforMETTL14 decreases FTH1 mRNA stability via m6A methylation to promote sorafenib-induced ferroptosis of cervical cancer | Full Text | References | PDF (12.5 MB) | EPUB
  • 1608 Views
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Article
Comparative analysis of the tumor microbiome, molecular profiles, and immune cell abundances by HPV status in mucosal head and neck cancers and their impact on survival
Rituraj Upadhyay, Aastha Dhakal, Caroline Wheeler, Rebecca Hoyd, Malvenderjit Jagjit Singh, Vidhya Karivedu, Priyanka Bhateja, Marcelo Bonomi, Sasha Valentin, Mauricio E. Gamez, David J. Konieczkowski, Sujith Baliga, John C. Grecula, Dukagjin M. Blakaj, Emile Gogineni, Darrion L. Mitchell, Nicholas C. Denko, Daniel Spakowicz & Sachin R. Jhawar
Article: 2350249
Published online: 09 May 2024
AbstractforComparative analysis of the tumor microbiome, molecular profiles, and immune cell abundances by HPV status in mucosal head and neck cancers and their impact on survival | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
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Correction

Correction
Correction
Article: 2350871
Published online: 05 May 2024
CitationforCorrection | Full Text | PDF (359.4 KB) | EPUB
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Correction
Correction
Article: 2352926
Published online: 15 May 2024
First Page PreviewforCorrection | Full Text | PDF (1.4 MB) | EPUB
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Research Paper

Article
eIf3a mediates malignant biological behaviors in colorectal cancer through the PI3K/AKT signaling pathway
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Article: 2355703
Published online: 23 May 2024
AbstractforeIf3a mediates malignant biological behaviors in colorectal cancer through the PI3K/AKT signaling pathway | Full Text | References | PDF (7.8 MB) | EPUB | Supplemental
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Article
The prognostic marker KRT81 is involved in suppressing CD8 + T cells and predicts immunotherapy response for triple-negative breast cancer
Zhideng Yan, Zhihui Zhong, Chuanke Shi, Muyin Feng, Xiaoqiang Feng & Tong Liu
Article: 2355705
Published online: 22 May 2024
AbstractforThe prognostic marker KRT81 is involved in suppressing CD8 + T cells and predicts immunotherapy response for triple-negative breast cancer | Full Text | References | PDF (8.3 MB) | EPUB | Supplemental
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Review

Review Article
T-Cell redirecting bispecific antibodies: a review of a novel class of immuno-oncology for advanced prostate cancer
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Article: 2356820
Published online: 27 May 2024
AbstractforT-Cell redirecting bispecific antibodies: a review of a novel class of immuno-oncology for advanced prostate cancer | Full Text | References | PDF (371 KB) | EPUB
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Review Article
The interplay between the tumor microenvironment and tumor-derived small extracellular vesicles in cancer development and therapeutic response
Xuanyu Guo, Jiajun Song, Miao Liu, Xinyi Ou & Yongcan Guo
Article: 2356831
Published online: 20 May 2024
AbstractforThe interplay between the tumor microenvironment and tumor-derived small extracellular vesicles in cancer development and therapeutic response | Full Text | References | PDF (3.4 MB) | EPUB
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NRS2002 score as a prognostic factor in solid tumors treated with immune checkpoint inhibitor therapy: a real-world evidence analysis
Wanfen Tang, Chenghui Li, Dong Huang, Shishi Zhou, Hongjuan Zheng, Qinghua Wang, Xia Zhang & Jianfei Fu
Article: 2358551
Published online: 30 May 2024
AbstractforNRS2002 score as a prognostic factor in solid tumors treated with immune checkpoint inhibitor therapy: a real-world evidence analysis | Full Text | References | PDF (2.3 MB) | EPUB
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Circ_RPPH1 facilitates progression of breast cancer via miR-1296-5p/TRIM14 axis
Jing Jiang, Shenghong Shi, Wei Zhang, Chao Li, Long Sun, Qidong Ge & Xujun Li
Article: 2360768
Published online: 30 May 2024
AbstractforCirc_RPPH1 facilitates progression of breast cancer via miR-1296-5p/TRIM14 axis | Full Text | References | PDF (7.9 MB) | EPUB | Supplemental
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P4HA2 promotes tumor progression and is transcriptionally regulated by SP1 in colorectal cancer
Xuening Dang, Xiaojian Chen, Zhonglin Liang, Zhujiang Dai, Wenjun Ding, Jinglue Song & Jihong Fu
Article: 2361594
Published online: 10 Jun 2024
AbstractforP4HA2 promotes tumor progression and is transcriptionally regulated by SP1 in colorectal cancer | Full Text | References | PDF (7.8 MB) | EPUB | Supplemental
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Research paper

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Neuroendocrine gene subsets are uniquely dysregulated in prostate adenocarcinoma
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Article: 2364433
Published online: 26 Jun 2024
AbstractforNeuroendocrine gene subsets are uniquely dysregulated in prostate adenocarcinoma | Full Text | References | PDF (1.6 MB) | EPUB
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Research Paper

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Xuewen Yang, Shisen Li, Chunsheng Xu, Shushang Liu, Xiang Zhang, Bo Lian & Mengbin Li
Article: 2365449
Published online: 12 Jun 2024
AbstractforSirtuin1 (sirt1) regulates the glycolysis pathway and decreases cisplatin chemotherapeutic sensitivity to esophageal squamous cell carcinoma | Full Text | References | PDF (7.5 MB) | EPUB | Supplemental
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Article
Effects of combined radiotherapy with immune checkpoint blockade on immunological memory in luminal-like subtype murine bladder cancer model
JiaMin Huang, Eva Michaud, Surashri Shinde-Jadhav, Sabina Fehric, Gautier Marcq, Jose Joao Mansure, Fabio Cury, Fadi Brimo, Ciriaco A. Piccirillo & Wassim Kassouf
Article: 2365452
Published online: 11 Jun 2024
AbstractforEffects of combined radiotherapy with immune checkpoint blockade on immunological memory in luminal-like subtype murine bladder cancer model | Full Text | References | PDF (2.3 MB) | EPUB | Supplemental
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Article
Role of transforming growth factor-β1 pathway in angiogenesis induced by chronic stress in colorectal cancer
Jie Zhang, Yao-Tiao Deng, Jie Liu, Lu Gan & Yu Jiang
Article: 2366451
Published online: 10 Jun 2024
AbstractforRole of transforming growth factor-β1 pathway in angiogenesis induced by chronic stress in colorectal cancer | Full Text | References | PDF (3.3 MB) | EPUB
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Article
The predictors of lymphopenia and its effects on survival in locally advanced esophageal squamous cell carcinoma
Danjing Luo, Qiulu Zhong, Haiying Yue, Jue Wang, Qianfu Liang, Wenqi Liu & Xiaodong Zhu
Article: 2371632
Published online: 01 Jul 2024
AbstractforThe predictors of lymphopenia and its effects on survival in locally advanced esophageal squamous cell carcinoma | Full Text | References | PDF (541.8 KB) | EPUB
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Article
Jmjd2c maintains the ALDHbri+ cancer stemness with transcription factor SOX2 in lung squamous cell carcinoma
Min Wang, Yuling Hu, Feng Cai, Lili Guo, Yimin Mao & Yingmin Zhang
Article: 2373447
Published online: 08 Jul 2024
AbstractforJmjd2c maintains the ALDHbri+ cancer stemness with transcription factor SOX2 in lung squamous cell carcinoma | Full Text | References | PDF (6.2 MB) | EPUB | Supplemental
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Article
MiR-135b-5p promotes cetuximab resistance in colorectal cancer by regulating FOXN3
Chun Peng, Xiaoqing Li, Yuhui Yao, Yu Nie, Lingyao Fan & Chuandong Zhu
Article: 2373497
Published online: 05 Jul 2024
AbstractforMiR-135b-5p promotes cetuximab resistance in colorectal cancer by regulating FOXN3 | Full Text | References | PDF (7.4 MB) | EPUB
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Correction

Correction
Correction
Article: 2375109
Published online: 01 Jul 2024
CitationforCorrection | Full Text | PDF (782.2 KB) | EPUB
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Article
BRG1 promotes liver cancer cell proliferation and metastasis by enhancing mitochondrial function and ATP5A1 synthesis through TOMM40
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Article: 2375440
Published online: 08 Jul 2024
AbstractforBRG1 promotes liver cancer cell proliferation and metastasis by enhancing mitochondrial function and ATP5A1 synthesis through TOMM40 | Full Text | References | PDF (15.3 MB) | EPUB | Supplemental
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Review

Review Article
Natural killer cell memory: challenges and opportunities for cancer immunotherapy
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Article: 2376410
Published online: 10 Jul 2024
AbstractforNatural killer cell memory: challenges and opportunities for cancer immunotherapy | Full Text | References | PDF (1.2 MB) | EPUB
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Research Paper

Article
Mechanism investigation of Forsythoside A against esophageal squamous cell carcinoma in vitro and in vivo
Yingying Yang, Junru Shen, Peiyuan Deng & Ping Chen
Article: 2380023
Published online: 24 Jul 2024
AbstractforMechanism investigation of Forsythoside A against esophageal squamous cell carcinoma in vitro and in vivo | Full Text | References | PDF (21.7 MB) | EPUB
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Review

Review Article
Association between the IL1B-511 C>T polymorphism and the risk of hematologic malignancies: data from a meta-analysis
Fabíola Silva Alves-Hanna, Felipe Rodolfo Pereira Silva, Daniele Sá Pereira, Alessandro Luiz Araújo Bentes Leal, Fábio Magalhães-Gama & Allyson Guimarães Costa
Article: 2382503
Published online: 22 Jul 2024
AbstractforAssociation between the IL1B-511 C>T polymorphism and the risk of hematologic malignancies: data from a meta-analysis | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
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