363
Views
0
CrossRef citations to date
0
Altmetric
Research paper

Jmjd2c maintains the ALDHbri+ cancer stemness with transcription factor SOX2 in lung squamous cell carcinoma

, , , , & ORCID Icon
Article: 2373447 | Received 08 Aug 2023, Accepted 24 Jun 2024, Published online: 08 Jul 2024

References

  • Yuan X, He J, Sun F, Gu J. Effects and interactions of MiR-577 and TSGA10 in regulating esophageal squamous cell carcinoma. Int J Clin Exp Pathol. 2013;6(12):2651–11.
  • Li Y, Gu J, Xu F, Zhu Q, Ge D, Lu C. Transcriptomic and functional network features of lung squamous cell carcinoma through integrative analysis of GEO and TCGA data. Sci Rep. 2018;8(1):15834. doi:10.1038/s41598-018-34160-w.
  • Chen JW, Dhahbi J. Lung adenocarcinoma and lung squamous cell carcinoma cancer classification, biomarker identification, and gene expression analysis using overlapping feature selection methods. Sci Rep. 2021;11(1):13323. doi:10.1038/s41598-021-92725-8.
  • Xue Y, Gao S, Gou J, Yin T, He H, Wang Y, Zhang Y, Tang X, Wu R. Platinum-based chemotherapy in combination with PD-1/PD-L1 inhibitors: preclinical and clinical studies and mechanism of action. Expert Opin Drug Deliv. 2021;18(2):187–203. doi:10.1080/17425247.2021.1825376.
  • Croagh D, Thomas RJ, Phillips WA, Kaur P. Esophageal stem cells—a review of their identification and characterization. Stem Cell Rev. 2008;4(4):261–68. doi:10.1007/s12015-008-9031-3.
  • Miranda Furtado CL, Dos Santos Luciano MC, Silva Santos RD, Furtado GP, Moraes MO, Pessoa C. Epidrugs: targeting epigenetic marks in cancer treatment. Epigenet. 2019;14(12):1164–76. doi:10.1080/15592294.2019.1640546.
  • Zhao L, Duan YT, Lu P, Zhang ZJ, Zheng XK, Wang JL, Feng WS. Epigenetic targets and their inhibitors in cancer therapy. Curr Top Med Chem. 2018;18(28):2395–419. doi:10.2174/1568026619666181224095449.
  • Nebbioso A, Tambaro FP, Dell’aversana C, Altucci L, Greally JM. Cancer epigenetics: moving forward. PloS Genet. 2018;14(6):e1007362. doi:10.1371/journal.pgen.1007362.
  • Zhang L, Lu Q, Chang C. Epigenetics in health and disease. Adv Exp Med Biol. 2020;1253:3–55.
  • Sigalotti L, Fratta E, Coral S, Cortini E, Covre A, Nicolay HJ, Anzalone L, Pezzani L, Di Giacomo AM, Fonsatti E, et al. Epigenetic drugs as pleiotropic agents in cancer treatment: biomolecular aspects and clinical applications. J Cell Physiol. 2007;212(2):330–44. doi:10.1002/jcp.21066.
  • Perillo B, Tramontano A, Pezone A, Migliaccio A. LSD1: more than demethylation of histone lysine residues. Experiment Molecul Med. 2020;52(12):1936–47. doi:10.1038/s12276-020-00542-2.
  • Yang J, Hu Y, Zhang B, Liang X, Li X. The JMJD family histone demethylases in crosstalk between inflammation and cancer. Front Immunol. 2022;13:881396. doi:10.3389/fimmu.2022.881396.
  • Zhang H, Wang J, Huang J, Shi T, Ma X, Luo X, Li X, Li M. Inhibiting Jumoji domain containing protein 3 (JMJD3) prevent neuronal apoptosis from stroke. Exp Neurol. 2018;308:132–42. doi:10.1016/j.expneurol.2018.07.007.
  • Yang ZQ, Imoto I, Fukuda Y, Pimkhaokham A, Shimada Y, Imamura M, Sugano S, Nakamura Y, Inazawa J. Identification of a novel gene, GASC1, within an amplicon at 9p23-24 frequently detected in esophageal cancer cell lines. Cancer Res. 2000;60(17):4735–39.
  • Hyun K, Jeon J, Park K, Kim J. Writing, erasing and reading histone lysine methylations. Experim Molecul Med. 2017;49(4):e324. doi:10.1038/emm.2017.11.
  • Tomaz RA, Harman JL, Karimlou D, Weavers L, Fritsch L, Bou-Kheir T, Bell E, Del Valle Torres I, Niakan KK, Fisher C, et al. Jmjd2c facilitates the assembly of essential enhancer-protein complexes at the onset of embryonic stem cell differentiation. Develop. 2017;144(4):567–79. doi:10.1242/dev.142489.
  • Zhang C, Wang Z, Ji Q, Li Q. Histone demethylase JMJD2C: epigenetic regulators in tumors. Oncotarget. 2017;8(53):91723–33. doi:10.18632/oncotarget.19176.
  • Li X, Dong S. Histone demethylase JMJD2B and JMJD2C induce fibroblast growth factor 2: mediated tumorigenesis of osteosarcoma. Med Oncol. 2015;32(3):53. doi:10.1007/s12032-015-0503-4.
  • An Y, Cai H, Zhang Y, Liu S, Duan Y, Sun D, Chen X, He X. circZMYM2 competed endogenously with miR-335-5p to regulate JMJD2C in pancreatic cancer. Cell Physiol Biochem. 2018;51(5):2224–36. doi:10.1159/000495868.
  • Hong Q, Yu S, Yang Y, Liu G, Shao Z. A polymorphism in JMJD2C alters the cleavage by caspase-3 and the prognosis of human breast cancer. Oncotarget. 2014;5(13):4779–87. doi:10.18632/oncotarget.2029.
  • Li N, Jiang D. Jumonji domain containing 2C promotes cell migration and invasion through modulating CUL4A expression in lung cancer. Biomed Pharmacother. 2017;89:305–15. doi:10.1016/j.biopha.2017.02.014.
  • Walcher L, Kistenmacher AK, Suo H, Kitte R, Dluczek S, Strauss A, Blaudszun AR, Yevsa T, Fricke S, Kossatz-Boehlert U. Cancer stem cells—origins and biomarkers: perspectives for targeted personalized therapies. Front Immunol. 2020;11:1280. doi:10.3389/fimmu.2020.01280.
  • Kusoglu A, Biray Avci Ç. Cancer stem cells: a brief review of the current status. Gene. 2019;681:80–85. doi:10.1016/j.gene.2018.09.052.
  • Dawood S, Austin L, Cristofanilli M. Cancer stem cells: implications for cancer therapy. Oncol (Williston Park). 2014;28(12):1101–7, 1110.
  • Porter L, McCaughan F. SOX2 and squamous cancers. Semin Cancer Biol. 2020;67(Pt 1):154–67. doi:10.1016/j.semcancer.2020.05.007.
  • Zhu Y, Huang S, Chen S, Chen J, Wang Z, Wang Y, Zheng H. SOX2 promotes chemoresistance, cancer stem cells properties, and epithelial–mesenchymal transition by β-catenin and Beclin1/autophagy signaling in colorectal cancer. Cell Death Dis. 2021;12(5):449. doi:10.1038/s41419-021-03733-5.
  • Chen X, Xie R, Gu P, Huang M, Han J, Dong W, Xie W, Wang B, He W, Zhong G, et al. Long noncoding RNA LBCS inhibits self-renewal and chemoresistance of bladder cancer stem cells through epigenetic silencing of SOX2. Clin Cancer Res. 2019;25(4):1389–403. doi:10.1158/1078-0432.CCR-18-1656.
  • Wu F, Wang L, Zhou C. Lung cancer in China: current and prospect. Curr Opin Oncol. 2021;33(1):40–46. doi:10.1097/CCO.0000000000000703.
  • Hirsch FR, Scagliotti GV, Mulshine JL, Kwon R, Curran WJ Jr., Wu YL, Paz-Ares L. Lung cancer: current therapies and new targeted treatments. Lancet. 2017;389(10066):299–311. doi:10.1016/S0140-6736(16)30958-8.
  • Kulasingam V, Diamandis EP. Strategies for discovering novel cancer biomarkers through utilization of emerging technologies. Nat Clin Pract Oncol. 2008;5(10):588–99. doi:10.1038/ncponc1187.
  • Zhang J, Wang M, Wang J, Wang W. JMJD2C-mediated long non-coding RNA MALAT1/microRNA-503-5p/SEPT2 axis worsens non-small cell lung cancer. Cell Death Dis. 2022;13(1):65. doi:10.1038/s41419-022-04513-5.
  • Najafi M, Mortezaee K, Majidpoor J. Cancer stem cell (CSC) resistance drivers. Life Sci. 2019;234:116781. doi:10.1016/j.lfs.2019.116781.
  • Peiris-Pages M, Martinez-Outschoorn UE, Pestell RG, Sotgia F, Lisanti MP. Cancer stem cell metabolism. Breast Cancer Res. 2016;18(1):55. doi:10.1186/s13058-016-0712-6.
  • Black JC, Van Rechem C, Whetstine JR. Histone lysine methylation dynamics: establishment, regulation, and biological impact. Mol Cell. 2012;48(4):491–507. doi:10.1016/j.molcel.2012.11.006.
  • Tsukada Y, Fang J, Erdjument-Bromage H, Warren ME, Borchers CH, Tempst P, Zhang Y. Histone demethylation by a family of JmjC domain-containing proteins. Nature. 2006;439(7078):811–16. doi:10.1038/nature04433.
  • Novak D, Huser L, Elton JJ, Umansky V, Altevogt P, Utikal J. SOX2 in development and cancer biology. Semin Cancer Biol. 2020;67(Pt 1):74–82. doi:10.1016/j.semcancer.2019.08.007.
  • Funaya S, Aoki F. Regulation of zygotic gene activation by chromatin structure and epigenetic factors. J Reprod Dev. 2017;63(4):359–63. doi:10.1262/jrd.2017-058.
  • Lawrence M, Daujat S, Schneider R. Lateral thinking: How histone modifications regulate gene expression. Trends Genet. 2016;32(1):42–56. doi:10.1016/j.tig.2015.10.007.
  • Zhuang X, Zhang W, Chen Y, Han X, Li J, Zhang Y, Zhang Y, Zhang S, Liu B. Doxorubicin-enriched, ALDHbr mouse breast cancer stem cells are treatable to oncolytic herpes simplex virus type 1. BMC Cancer. 2012;12(1):549. doi:10.1186/1471-2407-12-549.