Foot-and-mouth disease virus structural protein VP3 degrades Janus kinase 1 to inhibit IFN-γ signal transduction pathways

References

• Woolhouse M, Chase-Topping M, Haydon D, Friar J, Matthews L, Hughes G, Shaw D, Wilesmith J, Donaldson A, Cornell S, et al. Epidemiology. Foot-and-mouth disease under control in the UK. Nature 2001; 411:258-9; PMID:11357118; http://dx.doi.org/10.1038/35077149
   PubMed Web of Science ®Google Scholar
• Belsham GJ. Distinctive features of foot-and-mouth disease virus, a member of the picornavirus family; aspects of virus protein synthesis, protein processing and structure. Prog Biophys Mol Biol 1993; 60:241-60; PMID:8396787; http://dx.doi.org/10.1016/0079-6107(93)90016-D
   PubMed Web of Science ®Google Scholar
• Toka FN, Golde WT. Cell mediated innate responses of cattle and swine are diverse during foot-and-mouth disease virus (FMDV) infection: a unique landscape of innate immunity. Immunol Lett 2013; 152:135-43; PMID:23727070; http://dx.doi.org/10.1016/j.imlet.2013.05.007
   PubMed Web of Science ®Google Scholar
• Golde WT, Nfon CK, Toka FN. Immune evasion during foot-and-mouth disease virus infection of swine. Immunol Rev 2008; 225:85-95; PMID:18837777; http://dx.doi.org/10.1111/j.1600-065X.2008.00672.x
   PubMed Web of Science ®Google Scholar
• Grubman MJ, Moraes MP, Segundo FDS, Pena L, de los Santos T. Evading the host immune response: how foot-and-mouth disease virus has become an effective pathogen. Fems Immunol Med Mic 2008; 53:8-17; http://dx.doi.org/10.1111/j.1574-695X.2008.00409.x
   PubMedGoogle Scholar
• Summerfield A, Guzylack-Piriou L, Harwood L, McCullough KC. Innate immune responses against foot-and-mouth disease virus: current understanding and future directions. Vet Immunol Immunop 2009; 128:205-10; http://dx.doi.org/10.1016/j.vetimm.2008.10.296
   PubMed Web of Science ®Google Scholar
• Samuel CE. Antiviral actions of interferons. Clin Microbiol Rev 2001; 14:778-809; PMID:11585785; http://dx.doi.org/10.1128/CMR.14.4.778-809.2001
   PubMed Web of Science ®Google Scholar
• Yao QX, Huang QF, Cao Y, Qian P, Chen HC. Porcine interferon-gamma protects swine from foot-and-mouth disease virus (FMDV). Vet Immunol Immunop 2008; 122:309-11; http://dx.doi.org/10.1016/j.vetimm.2007.09.004
   PubMed Web of Science ®Google Scholar
• Sadler AJ, Williams BRG. Interferon-inducible antiviral effectors. Nat Rev Immunol 2008; 8:559-68; PMID:18575461; http://dx.doi.org/10.1038/nri2314
   PubMed Web of Science ®Google Scholar
• Platanias LC. Mechanisms of type-I- and type-II-interferon-mediated signalling. Nat Rev Immunol 2005; 5:375-86; PMID:15864272; http://dx.doi.org/10.1038/nri1604
   PubMed Web of Science ®Google Scholar
• Schindler C, Levy DE, Decker T. JAK-STAT signaling: From interferons to cytokines. J Biol Chem 2007; 282:20059-63; PMID:17502367; http://dx.doi.org/10.1074/jbc.R700016200
   PubMed Web of Science ®Google Scholar
• Stark GR, Kerr IM, Williams BRG, Silverman RH, Schreiber RD. How cells respond to interferons. Annu Rev Biochem 1998; 67:227-64; PMID:9759489; http://dx.doi.org/10.1146/annurev.biochem.67.1.227
   PubMed Web of Science ®Google Scholar
• Raghavan B, Cook CH, Trgovcich J. The Carboxy Terminal Region of the Human Cytomegalovirus Immediate Early 1 (IE1) Protein Disrupts Type II Inteferon Signaling. Viruses-Basel 2014; 6:1502-24; http://dx.doi.org/10.3390/v6041502
   PubMed Web of Science ®Google Scholar
• Goodbourn S, Didcock L, Randall RE. Interferons: cell signalling, immune modulation, antiviral response and virus countermeasures. J Gen Virol 2000; 81:2341-64; PMID:10993923; http://dx.doi.org/10.1099/0022-1317-81-10-2341
   PubMed Web of Science ®Google Scholar
• Guzylack-Piriou L, Bergamin F, Gerber M, McCullough KC, Summerfield A. Plasmacytoid dendritic cell activation by foot-and-mouth disease virus requires immune complexes. Eur J Immunol 2006; 36:1674-83; PMID:16783856; http://dx.doi.org/10.1002/eji.200635866
   PubMed Web of Science ®Google Scholar
• de Los Santos T, de Avila Botton S, Weiblen R, Grubman MJ. The leader proteinase of foot-and-mouth disease virus inhibits the induction of β interferon mRNA and blocks the host innate immune response. J Virol 2006; 80:1906-14; PMID:16439546; http://dx.doi.org/10.1128/JVI.80.4.1906-1914.2006
   PubMed Web of Science ®Google Scholar
• Wen X, Kudo T, Payne L, Wang X, Rodgers L, Suzuki Y. Predominant interferon-gamma-mediated expression of CXCL9, CXCL10, and CCL5 proteins in the brain during chronic infection with Toxoplasma gondii in BALB/c mice resistant to development of toxoplasmic encephalitis. J Interf Cytok Res 2010; 30:653-60; http://dx.doi.org/10.1089/jir.2009.0119
   PubMed Web of Science ®Google Scholar
• Ostrowski M, Vermeulen M, Zabal O, Geffner JR, Sadir AM, Lopez OJ. Impairment of thymus-dependent responses by murine dendritic cells infected with foot-and-mouth disease virus. J Immunol 2005; 175:3971-9; PMID:16148145; http://dx.doi.org/10.4049/jimmunol.175.6.3971
   PubMed Web of Science ®Google Scholar
• de Los Santos T, Diaz-San Segundo F, Grubman MJ. Degradation of nuclear factor kappa B during foot-and-mouth disease virus infection. J Virol 2007; 81:12803-15; PMID:17881445; http://dx.doi.org/10.1128/JVI.01467-07
   PubMed Web of Science ®Google Scholar
• Medina M, Domingo E, Brangwyn JK, Belsham GJ. The two species of the foot-and-mouth disease virus leader protein, expressed individually, exhibit the same activities. Virology 1993; 194:355-9; PMID:8386879; http://dx.doi.org/10.1006/viro.1993.1267
   PubMed Web of Science ®Google Scholar
• Du Y, Bi J, Liu J, Liu X, Wu X, Jiang P, Yoo D, Zhang Y, Wu J, Wan R, et al. 3Cpro of foot-and-mouth disease virus antagonizes the interferon signaling pathway by blocking STAT1/STAT2 nuclear translocation. J Virol 2014; 88:4908-20; PMID:24554650; http://dx.doi.org/10.1128/JVI.03668-13
   PubMed Web of Science ®Google Scholar
• Li X, Wang J, Liu J, Li Z, Wang Y, Xue Y, Li X, Cao H, Zheng SJ. Engagement of soluble resistance-related calcium binding protein (sorcin) with foot-and-mouth disease virus (FMDV) VP1 inhibits type I interferon response in cells. Vet Microbiol 2013; 166:35-46; PMID:23764275; http://dx.doi.org/10.1016/j.vetmic.2013.04.028
   PubMed Web of Science ®Google Scholar
• Ostler N, Britzen-Laurent N, Liebl A, Naschberger E, Lochnit G, Ostler M, Forster F, Kunzelmann P, Ince S, Supper V, et al. Gamma Interferon-Induced Guanylate Binding Protein 1 Is a Novel Actin Cytoskeleton Remodeling Factor. Mol Cell Biol 2014; 34:196-209; PMID:24190970; http://dx.doi.org/10.1128/MCB.00664-13
   PubMed Web of Science ®Google Scholar
• Cheng YS, Colonno RJ, Yin FH. Interferon induction of fibroblast proteins with guanylate binding activity. J Biol Chem 1983; 258:7746-50; PMID:6305951
   PubMed Web of Science ®Google Scholar
• Lubeseder-Martellato C, Guenzi E, Jorg A, Topolt K, Naschberger E, Kremmer E, Zietz C, Tschachler E, Hutzler P, Schwemmle M, et al. Guanylate-binding protein-1 expression is selectively induced by inflammatory cytokines and is an activation marker of endothelial cells during inflammatory diseases. Am J Pathol 2002; 161:1749-59; PMID:12414522; http://dx.doi.org/10.1016/S0002-9440(10)64452-5
   PubMed Web of Science ®Google Scholar
• Rosowski EE, Nguyen QP, Camejo A, Spooner E, Saeij JP. Toxoplasma gondii Inhibits gamma interferon (IFN-gamma)- and IFN-β-induced host cell STAT1 transcriptional activity by increasing the association of STAT1 with DNA. Infect Immun 2014; 82:706-19; PMID:24478085; http://dx.doi.org/10.1128/IAI.01291-13
   PubMed Web of Science ®Google Scholar
• Schindler C, Strehlow I. Cytokines and STAT signaling. Adv Pharmacol 2000; 47:113-74; PMID:10582086; http://dx.doi.org/10.1016/S1054-3589(08)60111-8
   PubMedGoogle Scholar
• Gough DJ, Levy DE, Johnstone RW, Clarke CJ. IFNgamma signaling-does it mean JAK-STAT? Cytokine Growth F R 2008; 19:383-94; http://dx.doi.org/10.1016/j.cytogfr.2008.08.004
   PubMed Web of Science ®Google Scholar
• Dupuis S, Jouanguy E, Al-Hajjar S, Fieschi C, Al-Mohsen IZ, Al-Jumaah S, Yang K, Chapgier A, Eidenschenk C, Eid P, et al. Impaired response to interferon-α/β and lethal viral disease in human STAT1 deficiency. Nat Genet 2003; 33:388-91; PMID:12590259; http://dx.doi.org/10.1038/ng1097
   PubMed Web of Science ®Google Scholar
• Sung YY, Kim HK. Illicium verum extract suppresses IFN-gamma-induced ICAM-1 expression via blockade of JAK/STAT pathway in HaCaT human keratinocytes. J Ethnopharmacol 2013; 149:626-32; PMID:23872327; http://dx.doi.org/10.1016/j.jep.2013.07.013
   PubMed Web of Science ®Google Scholar
• Andl CD, Mizushima T, Oyama K, Bowser M, Nakagawa H, Rustgi AK. EGFR-induced cell migration is mediated predominantly by the JAK-STAT pathway in primary esophageal keratinocytes. Am J Physiol-Gastr L 2004; 287:G1227-G37
   PubMed Web of Science ®Google Scholar
• Baum A, Garcia-Sastre A. Differential recognition of viral RNA by RIG-I. Virulence 2011; 2:166-9; PMID:21422808; http://dx.doi.org/10.4161/viru.2.2.15481
   PubMed Web of Science ®Google Scholar
• Rodriguez JJ, Parisien JP, Horvath CM. Nipah virus V protein evades α and gamma interferons by preventing STAT1 and STAT2 activation and nuclear accumulation. J Virol 2002; 76:11476-83; PMID:12388709; http://dx.doi.org/10.1128/JVI.76.22.11476-11483.2002
   PubMed Web of Science ®Google Scholar
• Randall RE, Goodbourn S. Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures. J GenVirol 2008; 89:1-47
   Web of Science ®Google Scholar
• Wang D, Fang L, Luo R, Ye R, Fang Y, Xie L, Chen H, Xiao S. Foot-and-mouth disease virus leader proteinase inhibits dsRNA-induced type I interferon transcription by decreasing interferon regulatory factor 3/7 in protein levels. Biochem Bioph Res Co 2010; 399:72-8; http://dx.doi.org/10.1016/j.bbrc.2010.07.044
   PubMed Web of Science ®Google Scholar
• Wang D, Fang L, Liu L, Zhong H, Chen Q, Luo R, Liu X, Zhang Z, Chen H, Xiao S. Foot-and-mouth disease virus (FMDV) leader proteinase negatively regulates the porcine interferon-lambda1 pathway. Mol Immunol 2011; 49:407-12; PMID:21975014; http://dx.doi.org/10.1016/j.molimm.2011.09.009
   PubMed Web of Science ®Google Scholar
• Wang D, Fang L, Li K, Zhong H, Fan J, Ouyang C, Zhang H, Duan E, Luo R, Zhang Z, et al. Foot-and-mouth disease virus 3C protease cleaves NEMO to impair innate immune signaling. J Virol 2012; 86:9311-22; PMID:22718831; http://dx.doi.org/10.1128/JVI.00722-12
   PubMed Web of Science ®Google Scholar
• Borca MV, Pacheco JM, Holinka LG, Carrillo C, Hartwig E, Garriga D, Kramer E, Rodriguez L, Piccone ME. Role of arginine-56 within the structural protein VP3 of foot-and-mouth disease virus (FMDV) O1 Campos in virus virulence. Virology 2012; 422:37-45; PMID:22036313; http://dx.doi.org/10.1016/j.virol.2011.09.031
   PubMed Web of Science ®Google Scholar
• Parisien JP, Lau JF, Rodriguez JJ, Sullivan BM, Moscona A, Parks GD, Lamb RA, Horvath CM. The V protein of human parainfluenza virus 2 antagonizes type I interferon responses by destabilizing signal transducer and activator of transcription 2. Virology 2001; 283:230-9; PMID:11336548; http://dx.doi.org/10.1006/viro.2001.0856
   PubMed Web of Science ®Google Scholar
• Ulane CM, Horvath CM. Paramyxoviruses SV5 and HPIV2 assemble STAT protein ubiquitin ligase complexes from cellular components. Virology 2002; 304:160-6; PMID:12504558; http://dx.doi.org/10.1006/viro.2002.1773
   PubMed Web of Science ®Google Scholar
• Garcin D, Marq JB, Strahle L, le Mercier P, Kolakofsky D. All four Sendai virus C proteins bind Stat1, but only the larger forms also induce its mono-ubiquitination and degradation. Virology 2002; 295:256-65; PMID:12033784; http://dx.doi.org/10.1006/viro.2001.1342
   PubMed Web of Science ®Google Scholar
• Komatsu T, Takeuchi K, Yokoo J, Gotoh B. Sendai virus C protein impairs both phosphorylation and dephosphorylation processes of Stat1. Febs Lett 2002; 511:139-44; PMID:11821064; http://dx.doi.org/10.1016/S0014-5793(01)03301-4
   PubMed Web of Science ®Google Scholar
• Palosaari H, Parisien JP, Rodriguez JJ, Ulane CM, Horvath CM. STAT protein interference and suppression of cytokine signal transduction by measles virus V protein. J Virol 2003; 77:7635-44; PMID:12805463; http://dx.doi.org/10.1128/JVI.77.13.7635-7644.2003
   PubMed Web of Science ®Google Scholar
• Takeuchi K, Kadota SI, Takeda M, Miyajima N, Nagata K. Measles virus V protein blocks interferon (IFN)-α/β but not IFN-gamma signaling by inhibiting STAT1 and STAT2 phosphorylation. Febs Lett 2003; 545:177-82; PMID:12804771; http://dx.doi.org/10.1016/S0014-5793(03)00528-3
   PubMed Web of Science ®Google Scholar
• Rodriguez JJ, Wang LF, Horvath CM. Hendra virus V protein inhibits interferon signaling by preventing STAT1 and STAT2 nuclear accumulation. J Virol 2003; 77:11842-5; PMID:14557668; http://dx.doi.org/10.1128/JVI.77.21.11842-11845.2003
   PubMed Web of Science ®Google Scholar
• Rodriguez JJ, Cruz CD, Horvath CM. Identification of the nuclear export signal and STAT-binding domains of the Nipah virus V protein reveals mechanisms underlying interferon evasion. J Virol 2004; 78:5358-67; PMID:15113915; http://dx.doi.org/10.1128/JVI.78.10.5358-5367.2004
   PubMed Web of Science ®Google Scholar
• Leffers H, Dejgaard K, Celis JE. Characterisation of two major cellular poly(rC)-binding human proteins, each containing three K-homologous (KH) domains. Eur J Biochem 1995; 230:447-53; PMID:7607214; http://dx.doi.org/10.1111/j.1432-1033.1995.tb20581.x
   PubMedGoogle Scholar
• Paulus C, Krauss S, Nevels M. A human cytomegalovirus antagonist of type I IFN-dependent signal transducer and activator of transcription signaling. PNAS 2006; 103:3840-5; PMID:16497831; http://dx.doi.org/10.1073/pnas.0600007103
   PubMed Web of Science ®Google Scholar
• Moniwa M, Clavijo A, Li MY, Collignon B, Kitching RP. Performance of a foot-and-mouth disease virus reverse transcription-polymerase chain reaction with amplification controls between three real-time instruments. J Vet Diagn Invest 2007; 19:9-20; PMID:17459827; http://dx.doi.org/10.1177/104063870701900103
   PubMed Web of Science ®Google Scholar