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Cell Cycle Volume 16, 2017 - Issue 14
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Editorials: Cell Cycle Features

Timely-regulated intron retention as device to fine-tune protein expression

Chiara NaroDepartment of Biomedicine and Prevention, University of Rome “Tor Vergata,”Rome, Italy;Laboratory of Neuroembryology, Fondazione Santa Lucia IRCCS, Rome, Italy
&
Claudio SetteDepartment of Biomedicine and Prevention, University of Rome “Tor Vergata,”Rome, Italy;Laboratory of Neuroembryology, Fondazione Santa Lucia IRCCS, Rome, ItalyCorrespondence[email protected]
Pages 1321-1322 | Received 11 May 2017, Accepted 22 May 2017, Published online: 23 Jun 2017

References

  • Lee Y, Rio DC. Mechanisms and regulation of alternative Pre-mRNA splicing. Annu Rev Biochem 2015; 84:291-323; PMID:25784052; https://doi.org/10.1146/annurev-biochem-060614-034316
  • Jacob AG, Smith CW. Intron retention as a component of regulated gene expression programs. Hum Genet 2017; Epub ahead of print; PMID:28391524; https://doi.org/10.1007/s00439-017-1791-x
  • Wong JJ, Ritchie W, Ebner OA, Selbach M, Wong JW, Huang Y, Gao D, Pinello N, Gonzalez M, Baidya K, Thoeng A, Khoo TL, Bailey CG, Holst J, Rasko JE. Orchestrated intron retention regulates normal granulocyte differentiation. Cell 2013; 154(3):583-95; PMID:23911323; https://doi.org/10.1016/j.cell.2013.06.052
  • Paronetto MP, Sette C. Role of RNA-binding proteins in mammalian spermatogenesis. Int J Androl 2010; 33:2-12; PMID:19281489; https://doi.org/10.1111/j.1365-2605.2009.00959.x
  • Naro C, Jolly A, Di Persio S, Bielli P, Setterblad N, Alberdi AJ, Vicini E, Geremia R, De la Grange P, Sette C. An orchestrated intron retention program in meiosis controls timely usage of transcripts during germ cell differentiation. Dev Cell 2017; 41:82-93.e4; PMID:28366282; https://doi.org/10.1016/j.devcel.2017.03.003
  • Shalgi R, Hurt JA, Lindquist S, Burge CB. Report widespread inhibition of posttranscriptional splicing shapes the cellular transcriptome following heat shock. Cell Rep 2014; 7:1362-70; PMID:24857664; https://doi.org/10.1016/j.celrep.2014.04.044
  • Mauger O, Lemoine F, Scheiffele P. Targeted intron retention and excision for rapid gene regulation in response to neuronal activity. Neuron 2016; 92:1266-78; PMID:28009274; https://doi.org/10.1016/j.neuron.2016.11.032
  • Hsu TY, Simon LM, Neill NJ, Marcotte R, Sayad A, Bland CS, Echeverria GV, Sun T, Kurley SJ, Tyagi S, Karlin KL, Dominguez-Vidaña R, Hartman JD, Renwick A, Scorsone K, Bernardi RJ, Skinner SO, Jain A, Orellana M, Lagisetti C, Golding I, Jung SY, Neilson JR, Zhang XH, Cooper TA, Webb TR, Neel BG, Shaw CA, Westbrook TF. The spliceosome is a therapeutic vulnerability in MYC-driven cancer. Nature [ Internet] 2015; 525:384-8; PMID:26331541; https://doi.org/10.1038/nature14985

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