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Research Paper

IGF1/IGF1R and microRNA let-7e down-regulate each other and modulate proliferation and migration of colorectal cancer cells

, , , , , , & show all
Pages 1212-1219 | Received 26 Nov 2017, Accepted 21 Apr 2018, Published online: 18 Jul 2018

References

  • Parkin DM, Pisani P, Ferlay J. Estimates of the worldwide incidence of 25 major cancers in 1990. Int J Cancer. 1999;80(6):827.
  • Siegel R, DeSantis C, Virgo K, et al. Cancer treatment and survivorship statistics, 2012. CA Cancer J Clin. 2012 Jul-Aug;62(4):220–241. Review.
  • Fürstenberger G, Senn HJ. Insulin-like growth factors and cancer. Lancet Oncol. 2002 May;3(5):298–302. Review.
  • Baserga R, Peruzzi F, Reiss K. The IGF-1 receptor in cancer biology. Int J Cancer. 2003 Dec 20;107(6):873–877.
  • Alberobello AT, D’Esposito V, Marasco D, et al. Selective disruption of insulin-like growth factor-1 (IGF-1) signaling via phosphoinositide-dependent kinase-1 prevents the protective effect of IGF-1 on human cancer cell death. J Biol Chem. 2010 Feb 26;285(9):6563–6572. . Epub 2009 Dec 31.
  • Reinmuth N, Liu W, Fan F, et al. Blockade of insulin-like growth factor I receptor function inhibits growth and angiogenesis of colon cancer. Clin Cancer Res. 2002 Oct;8(10):3259–3269.
  • Sekharam M, Zhao H, Sun M, et al. Insulin-like growth factor 1 receptor enhances invasion and induces resistance to apoptosis of colon cancer cells through the Akt/Bcl-x(L) pathway. Cancer Res. 2003 Nov 15;63(22):7708–7716.
  • Roush S, Slack FJ. The let-7 family of microRNAs. Trends Cell Biol. 2008 Oct;18(10):505–516. . Epub 2008 Sep 4.
  • Pasquinelli AE, Reinhart BJ, Slack F, et al. Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature. 2000 Nov 2;408(6808):86–89.
  • Jérôme T, Laurie P, Louis B, et al. Enjoy the silence: the story of let-7 MicroRNA and cancer. Curr Genomics. 2007 Jun;8(4):229–233.
  • Barh D, Malhotra R, Ravi B, et al. MicroRNA let-7: an emerging next-generation cancer therapeutic. Curr Oncol. 2010 Feb;17(1):70–80.
  • Esquela-Kerscher A, Trang P, Wiggins JF, et al. The let-7 microRNA reduces tumor growth in mouse models of lung cancer. Cell Cycle. 2008 Mar 15;7(6):759–764. Epub 2008 Mar 3.
  • Wu L, Nguyen LH, Zhou K, et al. Precise let-7 expression levels balance organ regeneration against tumor suppression. Elife. 2015 Oct 7;4:e09431.
  • Hikasa H, Sekido Y, Suzuki A. Merlin/NF2-Lin28B-let-7 is a tumor-suppressive pathway that is cell-density dependent and hippo independent. Cell Rep. 2016 Mar 29;14(12):2950–2961.
  • Johnson CD, Esquela-Kerscher A, Stefani G, et al. The let-7 microRNA represses cell proliferation pathways in human cells. Cancer Res. 2007 Aug 15;67(16):7713–7722.
  • Johnson SM, Grosshans H, Shingara J, et al. RAS is regulated by the let-7 microRNA family. Cell. 2005 Mar 11;120(5):635–647.
  • Mayr C, Hemann MT, Bartel DP. Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation. Science. 2007 Mar 16;315(5818):1576–1579. Epub 2007 Feb 22.
  • Newman MA, Thomson JM, Hammond SM. Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing. RNA. 2008 Aug;14(8):1539–1549. . Epub 2008 Jun 19.
  • Wei W, Zhang WY, Bai JB, et al. The NF-κB-modulated microRNAs miR-195 and miR-497 inhibit myoblast proliferation by targeting Igf1r, Insr and cyclin genes. J Cell Sci. 2016 Jan 1;129(1):39–50.
  • Kong KL, Kwong DL, Chan TH, et al. MicroRNA-375 inhibits tumour growth and metastasis in oesophageal squamous cell carcinoma through repressing insulin-like growth factor 1 receptor. Gut. 2012 Jan;61(1):33–42. . Epub 2011 Aug 3.
  • Jiang L, Liu X, Chen Z, et al. MicroRNA-7 targets IGF1R (insulin-like growth factor 1 receptor) in tongue squamous cell carcinoma cells. Biochem J. 2010 Nov 15;432(1):199–205. .
  • La Rocca G, Badin M, Shi B, et al. Mechanism of growth inhibition by MicroRNA 145: the role of the IGF-I receptor signaling pathway. J Cell Physiol. 2009 Aug;220(2):485–491. .
  • Lerman G, Avivi C, Mardoukh C, et al. MiRNA expression in psoriatic skin: reciprocal regulation of hsa-miR-99a and IGF-1R. PLoS One. 2011;6(6):e20916. Epub 2011 Jun 7.
  • Guo ST, Jiang CC, Wang GP, et al. MicroRNA-497 targets insulin-like growth factor 1 receptor and has a tumour suppressive role in human colorectal cancer. Oncogene. 2012 Jun 18. [Epub ahead of print]. DOI:10.1038/onc.2012.214
  • Shen K, Liang Q, Xu K, et al. MiR-139 inhibits invasion and metastasis of colorectal cancer by targeting the type I insulin-like growth factor receptor. Biochem Pharmacol. 2012 Aug 1;84(3):320–330. . Epub 2012 May 3.
  • Kreisberg JI, Malik SN, Prihoda TJ, et al. Phosphorylation of Akt (Ser473) is an excellent predictor of poor clinical outcome in prostate cancer. Cancer Res. 2004;64:5232–5236.
  • Jiang J, Lee EJ, Gusev Y, et al. Real-time expression profiling of microRNA precursors in human cancer cell lines. Nucleic Acids Res. 2005 Sep 28;33(17):5394–5403. Print 2005.
  • Oberthür R, Seemann H, Gehrig J, et al. Simultaneous inhibition of IGF1R and EGFR enhances the efficacy of standard treatment for colorectal cancer by the impairment of DNA repair and the induction of cell death. Cancer Lett. 2017 Oct 28;407:93–105.
  • Sanchez-Lopez E, Flashner-Abramson E, Shalapour S, et al. Targeting colorectal cancer via its microenvironment by inhibiting IGF-1 receptor-insulin receptor substrate and STAT3 signaling. Oncogene. 2016 May 19;35(20):2634–2644.
  • Hakam A, Yeatman TJ, Lu L, et al. Expression of insulin-like growth factor-1 receptor in human colorectal cancer. Hum Pathol. 1999 Oct;30(10):1128–1133.
  • Freier S, Weiss O, Eran M, et al. Expression of the insulin-like growth factors and their receptors in adenocarcinoma of the colon. Gut. 1999 May;44(5):704–708.
  • Michell NP, Langman MJ, Eggo MC. Insulin-like growth factors and their binding proteins in human colonocytes: preferential degradation of insulin-like growth factor binding protein 2 in colonic cancers. Br J Cancer. 1997;76(1):60–66.

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