Sirt7 inhibits Sirt1-mediated activation of Suv39h1

References

• Haigis MC, Sinclair DA. Mammalian sirtuins: biological insights and disease relevance. Annu Rev Pathol. 2010;5:253–295.
   PubMed Web of Science ®Google Scholar
• Bosch-Presegue L, Vaquero A. Sirtuins in stress response: guardians of the genome. Oncogene. 2014;33(29):3764–3775.
   PubMed Web of Science ®Google Scholar
• Martinez-Redondo P, Vaquero A. The diversity of histone versus nonhistone sirtuin substrates. Genes Cancer. 2013;4(3–4):148–163.
   PubMedGoogle Scholar
• Barber MF, Michishita-Kioi E, Xi Y, et al. SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation. Nature. 2012;487(7405):114–118.
   PubMed Web of Science ®Google Scholar
• Tasselli L, Xi Y, Zheng W, et al. SIRT6 deacetylates H3K18ac at pericentric chromatin to prevent mitotic errors and cellular senescence. Nat Struct Mol Biol. 2016;23(5):434–440.
   PubMed Web of Science ®Google Scholar
• Canto C, Auwerx J. Targeting sirtuin 1 to improve metabolism: all you need is NAD(+)? Pharmacol Rev. 2012;64(1):166–187.
   PubMed Web of Science ®Google Scholar
• Merksamer PI, Liu Y, He W, et al. The sirtuins, oxidative stress and aging: an emerging link. Aging (Albany NY). 2013;5(3):144–150.
   PubMedGoogle Scholar
• Oberdoerffer P, Michan S, McVay M, et al. SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging. Cell. 2008;135(5):907–918.
   PubMed Web of Science ®Google Scholar
• Cheng HL, Mostoslavsky R, Saito S, et al. Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proc Natl Acad Sci U S A. 2003;100(19):10794–10799.
   PubMed Web of Science ®Google Scholar
• Yuan X, Qi H, Li X, et al. Disruption of spatiotemporal hypoxic signaling causes congenital heart disease in mice. J Clin Invest. 2017;127(6):2235–2248.
   PubMed Web of Science ®Google Scholar
• Satoh A, Brace CS, Rensing N, et al. Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH. Cell Metab. 2013;18(3):416–430.
   PubMed Web of Science ®Google Scholar
• Li Y, Xu SQ, Giles A, et al. Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver. Faseb J. 2011;25(5):1664–1679.
   PubMed Web of Science ®Google Scholar
• Herranz D, Munoz-Martin M, Canamero M, et al. Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer. Nat Commun. 2010;1:3. doi:10.1038/ncomms1001
   PubMed Web of Science ®Google Scholar
• Alcendor RR, Gao SM, Zhai PY, et al. Sirt1 regulates aging and resistance to oxidative stress in the heart. Circ Res. 2007;100(10):1512–1521.
   PubMed Web of Science ®Google Scholar
• Kawashima T, Inuzuka Y, Okuda J, et al. Constitutive SIRT1 overexpression impairs mitochondria and reduces cardiac function in mice. J Mol Cell Cardiol. 2011;51(6):1026–1036.
   PubMed Web of Science ®Google Scholar
• Han C, Gu Y, Shan H, et al. O-GlcNAcylation of SIRT1 enhances its deacetylase activity and promotes cytoprotection under stress. Nat Commun. 2017;8(1):1491.
   PubMedGoogle Scholar
• Flick F, Luscher B. Regulation of sirtuin function by posttranslational modifications. Front Pharmacol. 2012;3:29.
   PubMed Web of Science ®Google Scholar
• Buler M, Andersson U, Hakkola J. Who watches the watchmen? Regulation of the expression and activity of sirtuins. Faseb J. 2016;30(12):3942–3960.
   PubMed Web of Science ®Google Scholar
• Fang J, Ianni A, Smolka C, et al. Sirt7 promotes adipogenesis in the mouse by inhibiting autocatalytic activation of Sirt1. Proc Natl Acad Sci U S A. 2017;114(40):E8352–E8361.
   PubMed Web of Science ®Google Scholar
• Vaquero A, Scher M, Erdjument-Bromage H, et al. SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation. Nature. 2007;450(7168):440–444.
   PubMed Web of Science ®Google Scholar
• Ianni A, Hoelper S, Krueger M, et al. Sirt7 stabilizes rDNA heterochromatin through recruitment of DNMT1 and Sirt1. Biochem Bioph Res Co. 2017;492(3):434–440.
   PubMed Web of Science ®Google Scholar
• Bosch-Presegue L, Raurell-Vila H, Marazuela-Duque A, et al. Stabilization of Suv39H1 by SirT1 is part of oxidative stress response and ensures genome protection. Mol Cell. 2011;42(2):210–223.
   PubMed Web of Science ®Google Scholar
• Napper AD, Hixon J, McDonagh T, et al. Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1. J Med Chem. 2005;48(25):8045–8054.
   PubMed Web of Science ®Google Scholar
• Ardito F, Giuliani M, Perrone D, et al. The crucial role of protein phosphorylation in cell signaling and its use as targeted therapy (Review). Int J Mol Med. 2017;40(2):271–280.
   PubMed Web of Science ®Google Scholar
• Yang C, Wu J, Sinha SH, et al. Autoacetylation of the MYST lysine acetyltransferase MOF protein. J Biol Chem. 2012;287(42):34917–34926.
   PubMed Web of Science ®Google Scholar
• Yuan H, Rossetto D, Mellert H, et al. MYST protein acetyltransferase activity requires active site lysine autoacetylation. EMBO J. 2012;31(1):58–70.
   PubMed Web of Science ®Google Scholar
• Karanam B, Jiang L, Wang L, et al. Kinetic and mass spectrometric analysis of p300 histone acetyltransferase domain autoacetylation. J Biol Chem. 2006;281(52):40292–40301.
   PubMed Web of Science ®Google Scholar
• Stiehl DP, Fath DM, Liang DM, et al. Histone deacetylase inhibitors synergize p300 autoacetylation that regulates its transactivation activity and complex formation. Cancer Res. 2007;67(5):2256–2264.
   PubMed Web of Science ®Google Scholar
• Lee N, Kim DK, Kim ES, et al. Comparative interactomes of SIRT6 and SIRT7: implication of functional links to aging. Proteomics. 2014;14(13–14):1610–1622.
   PubMed Web of Science ®Google Scholar
• Ting DT, Lipson D, Paul S, et al. Aberrant overexpression of satellite repeats in pancreatic and other epithelial cancers. Science. 2011;331(6017):593–596.
   PubMed Web of Science ®Google Scholar
• Bierhoff H, Postepska-Igielska A, Grummt I. Noisy silence Non-coding RNA and heterochromatin formation at repetitive elements. Epigenetics-Us. 2014;9(1):53–61.
   PubMed Web of Science ®Google Scholar
• Slee RB, Steiner CM, Herbert BS, et al. Cancer-associated alteration of pericentromeric heterochromatin may contribute to chromosome instability. Oncogene. 2012;31(27):3244–3253.
   PubMed Web of Science ®Google Scholar
• Putiri EL, Robertson KD. Epigenetic mechanisms and genome stability. Clin Epigenetics. 2011;2(2):299–314.
   PubMed Web of Science ®Google Scholar
• Blank MF, Grummt I. The seven faces of SIRT7. Transcr-Austin. 2017;8(2):67–74.
   Web of Science ®Google Scholar
• Wang D, Zhou J, Liu X, et al. Methylation of SUV39H1 by SET7/9 results in heterochromatin relaxation and genome instability. Proc Natl Acad Sci U S A. 2013;110(14):5516–5521.
   PubMed Web of Science ®Google Scholar
• Wang RH, Zhao TR, Cui KR, et al. Negative reciprocal regulation between Sirt1 and Per2 modulates the circadian clock and aging. Sci Rep-Uk. 2016;6:28633. doi:10.1038/srep28633.
   Web of Science ®Google Scholar
• Sambrook J, Russell DW. Calcium-phosphate-mediated Transfection of Eukaryotic Cells with Plasmid DNAs. CSH Protoc. 2006;2006(1). doi: 10.1101/pdb.prot3871
   Google Scholar
• Al-Furoukh N, Ianni A, Nolte H, et al. ClpX stimulates the mitochondrial unfolded protein response (UPRmt) in mammalian cells. Biochim Biophys Acta. 2015;1853(10 Pt A):2580–2591.
   PubMed Web of Science ®Google Scholar