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Monitoring dimeric status of IZUMO1 during the acrosome reaction in living spermatozoon

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Pages 1279-1285 | Received 12 Apr 2018, Accepted 19 May 2018, Published online: 25 Jul 2018

References

  • Bianchi E, Doe B, Goulding D, et al. Juno is the egg Izumo receptor and is essential for mammalian fertilization. Nature. 2014;508:483–487.
  • Inoue N, Ikawa M, Isotani A, et al. The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggs. Nature. 2005;434:234–238.
  • Kaji K, Oda S, Shikano T, et al. The gamete fusion process is defective in eggs of Cd9-deficient mice. Nat Genet. 2000;24:279–282.
  • Le Naour F, Rubinstein E, Jasmin C, et al. Severely reduced female fertility in CD9-deficient mice. Science. 2000;287:319–321.
  • Lorenzetti D, Poirier C, Zhao M, et al. A transgenic insertion on mouse chromosome 17 inactivates a novel immunoglobulin superfamily gene potentially involved in sperm-egg fusion. Mamm Genome: off J Int Mamm Genome Soc. 2014;25:141–148.
  • Miyado K, Yamada G, Yamada S, et al. Requirement of CD9 on the egg plasma membrane for fertilization. Science. 2000;287:321–324.
  • Ohto U, Ishida H, Krayukhina E, et al. Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization. Nature. 2016;534:566–569.
  • Inoue N, Hamada D, Kamikubo H, et al. Molecular dissection of IZUMO1, a sperm protein essential for sperm-egg fusion. Development. 2013;140:3221–3229.
  • Inoue N, Hagihara Y, Wright D, et al. Oocyte-triggered dimerization of sperm IZUMO1 promotes sperm-egg fusion in mice. Nat Commun. 2015;6:8858.
  • Inoue N. Novel insights into the molecular mechanism of sperm-egg fusion via IZUMO1. J Plant Res. 2017;130:475–478.
  • Jin M, Fujiwara E, Kakiuchi Y, et al. Most fertilizing mouse spermatozoa begin their acrosome reaction before contact with the zona pellucida during in vitro fertilization. Proceedings of the National Academy of Sciences of the United States of America 2011; 108:4892–4896.
  • La Spina FA, Puga Molina LC, Romarowski A, et al. Mouse sperm begin to undergo acrosomal exocytosis in the upper isthmus of the oviduct. Dev Biol. 2016;411:172–182.
  • Muro Y, Hasuwa H, Isotani A, et al. Behavior of mouse spermatozoa in the female reproductive tract from soon after mating to the beginning of fertilization. Biol Reprod. 2016;94:80.
  • Hino T, Muro Y, Tamura-Nakano M, et al. The behavior and acrosomal status of mouse spermatozoa in vitro, and within the oviduct during fertilization after natural mating. Biol Reprod. 2016;95:50.
  • Inoue N, Satouh Y, Ikawa M, et al. Acrosome-reacted mouse spermatozoa recovered from the perivitelline space can fertilize other eggs. Proceedings of the National Academy of Sciences of the United States of America 2011; 108:20008–20011.
  • Sato K, Blandau RJ. Time and process of sperm penetration into cumulus‐free mouse eggs fertilized in vitro. Gamete Res. 1979;2:295–304.
  • Yanagimachi R. Mammalian fertilization. New York (NY): Raven Press, LTD; 1994.
  • Satouh Y, Inoue N, Ikawa M, et al. Visualization of the moment of mouse sperm-egg fusion and dynamic localization of IZUMO1. J Cell Sci. 2012;125:4985–4990.
  • Young SA, Miyata H, Satouh Y, et al. CRISPR/Cas9-mediated mutation revealed cytoplasmic tail is dispensable for IZUMO1 function and male fertility. Reproduction. 2016;152:665–672.
  • Kodama Y, Hu CD. Bimolecular fluorescence complementation (BiFC): a 5-year update and future perspectives. Biotechniques. 2012;53:285–298.
  • Inoue N, Ikawa M, Okabe M. Putative sperm fusion protein IZUMO and the role of N-glycosylation. Biochem Biophys Res Commun. 2008;377:910–914.
  • Sosnik J, Miranda PV, Spiridonov NA, et al. Tssk6 is required for Izumo relocalization and gamete fusion in the mouse. J Cell Sci. 2009;122:2741–2749.
  • Zhou C, Huang L, Shi DS, et al. Effects of latrunculin A on the relocation of sperm IZUMO1 during gamete interaction in mouse. Mol Reprod Dev. 2017;84:1183–1190.
  • Frolikova M, Sebkova N, Ded L, et al. Characterization of CD46 and beta1 integrin dynamics during sperm acrosome reaction. Sci Rep. 2016;6:33714.
  • Nakanishi T, Ikawa M, Yamada S, et al. Real-time observation of acrosomal dispersal from mouse sperm using GFP as a marker protein. FEBS Lett. 1999;449:277–283.
  • Toyoda Y, Yokoyama M, Hoshi T. Studies on the fertilization of mouse eggs in vitro I: in vitro fertilization of eggs by fresh epididymal sperm [in Japanese]. Jpn J Anim Reprod. 1971;16:147–151.
  • Schindelin J, Arganda-Carreras I, Frise E, et al. Fiji: an open-source platform for biological-image analysis. Nat Methods. 2012;9:676–682.

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