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Research Paper

CIZ1-F, an alternatively spliced variant of the DNA replication protein CIZ1 with distinct expression and localisation, is overrepresented in early stage common solid tumours

ORCID Icon, ORCID Icon, & ORCID Icon
Pages 2268-2283 | Received 20 Jun 2018, Accepted 09 Sep 2018, Published online: 06 Oct 2018

References

  • Rahman FA, Aziz N, Coverley D. Differential detection of alternatively spliced variants of Ciz1 in normal and cancer cells using a custom exon-junction microarray. BMC Cancer. 2010;10:482.
  • Rahman F, Ainscough JF, Copeland N, et al. Cancer-associated missplicing of exon 4 influences the subnuclear distribution of the DNA replication factor CIZ1. Hum Mutat. 2007;28:993–1004.
  • Dahmcke CM, Buchmann-Moller S, Jensen NA, et al. Altered splicing in exon 8 of the DNA replication factor CIZ1 affects subnuclear distribution and is associated with Alzheimer’s disease. Mol Cell Neurosci. 2008;38:589–594.
  • Greaves EA, Copeland NA, Coverley D, et al. Cancer-associated variant expression and interaction of CIZ1 with cyclin A1 in differentiating male germ cells. J Cell Sci. 2012;125:2466–2477.
  • Higgins G, Roper KM, Watson IJ, et al. Variant Ciz1 is a circulating biomarker for early-stage lung cancer. Proc Natl Acad Sci USA. 2012;109:E3128–35.
  • Coverley D, Marr J, Ainscough J. Ciz1 promotes mammalian DNA replication. J Cell Sci. 2005;118:101–112.
  • Copeland NA, Sercombe HE, Ainscough JF, et al. Ciz1 cooperates with cyclin-A-CDK2 to activate mammalian DNA replication in vitro. J Cell Sci. 2010;123:1108–1115.
  • Ainscough JF, Rahman FA, Sercombe H, et al. C-terminal domains deliver the DNA replication factor Ciz1 to the nuclear matrix. J Cell Sci. 2007;120:115–124.
  • Ridings-Figueroa R, Stewart ER, Nesterova TB, et al. The nuclear matrix protein CIZ1 facilitates localization of Xist RNA to the inactive X-chromosome territory. Genes Dev. 2017;31:876–888.
  • Sunwoo H, Colognori D, Froberg JE, et al. Repeat E anchors Xist RNA to the inactive X chromosomal compartment through CDKN1A-interacting protein (CIZ1). Proc Natl Acad Sci USA. 2017;114:10654–10659.
  • Coverley D, Higgins G, West D, et al. A quantitative immunoassay for lung cancer biomarker CIZ1b in patient plasma. Clin Biochem. 2017;50:336–343.
  • Den Hollander P, Rayala SK, Coverley D, et al. Ciz1, a Novel DNA-binding coactivator of the estrogen receptor alpha, confers hypersensitivity to estrogen action. Cancer Res. 2006;66:11021–11029.
  • Siegel R, Ma J, Zou Z, et al. Cancer statistics. CA Cancer J Clin. 2014;64:9–29.
  • Xiao J, Uitti RJ, Zhao Y, et al. Mutations in CIZ1 cause adult onset primary cervical dystonia. Ann Neurol. 2012;71:458–469.
  • Den Hollander P, Kumar R. Dynein light chain 1 contributes to cell cycle progression by increasing cyclin-dependent kinase 2 activity in estrogen-stimulated cells. Cancer Res. 2006;66:5941–5949.
  • Mitsui K, Matsumoto A, Ohtsuka S, et al. Cloning and characterization of a novel p21(Cip1/Waf1)-interacting zinc finger protein, ciz1. Biochem Biophys Res Commun. 1999;264:457–464.
  • Lei L, Wu J, Gu D, et al. CIZ1 interacts with YAP and activates its transcriptional activity in hepatocellular carcinoma cells. Tumour Biol. 2016;37:11073–11079.
  • Copeland NA, Sercombe HE, Wilson RH, et al. Cyclin A/CDK2 phosphorylation of CIZ1 blocks replisome formation and initiation of mammalian DNA replication. J Cell Sci. 2015;128:1518–1527.
  • Jiang L, Luo X, Shi J, et al. PDRG1, a novel tumor marker for multiple malignancies that is selectively regulated by genotoxic stress. Cancer Biol Ther. 2011;11:567–573.
  • Thalappilly S, Suliman M, Gayet O, et al. Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach. Proteomics. 2008;8:3071–3081.
  • Zhang D, Wang Y, Dai Y, et al. CIZ1 promoted the growth and migration of gallbladder cancer cells. Tumour Biol. 2015;36:2583–2591.
  • Heery DM, Kalkhoven E, Hoare S, et al. A signature motif in transcriptional co-activators mediates binding to nuclear receptors. Nature. 1997;387:733–736.
  • Chaligne R, Popova T, Mendoza-Parra MA, et al. The inactive X chromosome is epigenetically unstable and transcriptionally labile in breast cancer. Genome Res. 2015;25:488–503.
  • Wilson RH, Coverley D. Relationship between DNA replication and the nuclear matrix. Genes Cells. 2013;18:17–31.
  • Zink D, Fischer AH, Nickerson JA. Nuclear structure in cancer cells. Nat Rev Cancer. 2004;4:677–687.
  • Spencer VA, Samuel SK, Davie JR. Nuclear matrix proteins associated with DNA in situ in hormone-dependent and hormone-independent human breast cancer cell lines. Cancer Res. 2000;60:288–292.
  • Samuel SK, Minish TM, Davie JR. Nuclear matrix proteins in well and poorly differentiated human breast cancer cell lines. J Cell Biochem. 1997;66:9–15.
  • Khanuja PS, Lehr JE, Soule HD, et al. Nuclear matrix proteins in normal and breast cancer cells. Cancer Res. 1993;53:3394–3398.
  • Wang DQ, Wang K, Yan DW, et al. Ciz1 is a novel predictor of survival in human colon cancer. Exp Biol Med. 2014;239:862–870.
  • Yin J, Wang C, Tang X, et al. CIZ1 regulates the proliferation, cycle distribution and colony formation of RKO human colorectal cancer cells. Mol Med Rep. 2013;8:1630–1634.
  • Zhou X, Liu Q, Wada Y, et al. CDKN1A-interacting zinc finger protein 1 is a novel biomarker for lung squamous cell carcinoma. Oncol Lett. 2018;15:183–188.
  • Liu T, Ren X, Li L, et al. Ciz1 promotes tumorigenicity of prostate carcinoma cells. Front Biosci (Landmark Ed). 2015;20:705–715.
  • Warder DE, Keherly MJ. Ciz1, Cip1 interacting zinc finger protein 1 binds the consensus DNA sequence ARYSR(0-2)YYAC. J Biomed Sci. 2003;10:406–417.
  • Nishibe R, Watanabe W, Ueda T, et al. CIZ1, a p21Cip1/Waf1-interacting protein, functions as a tumor suppressor in vivo. FEBS Lett. 2013;587:1529–1535.
  • Verheijen R, van Venrooij W, Ramaekers F. The nuclear matrix: structure and composition. J Cell Sci. 1988;90(Pt 1):11–36.
  • McInerney EM, Rose DW, Flynn SE, et al. Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation. Genes Dev. 1998;12:3357–3368.
  • Tait L, Soule HD, Russo J. Ultrastructural and immunocytochemical characterization of an immortalized human breast epithelial cell line, MCF-10. Cancer Res. 1990;50:6087–6094.
  • Swarts DR, Henfling ME, Van Neste L, et al. CD44 and OTP are strong prognostic markers for pulmonary carcinoids. Clin Cancer Res. 2013;19:2197–2207.
  • Wilson RHH, Hesketh EL, Coverley D. The nuclear matrix: fractionation techniques and analysis. In: Pryor PP, editor. Subcellular fractionation - a laboratory manual. New York: Cold Spring Harbor Laboratory Press; 2015. p. 223–233.
  • Hesketh EL, Knight JR, Wilson RH, et al. Transient association of MCM complex proteins with the nuclear matrix during initiation of mammalian DNA replication. Cell Cycle. 2015;14:333–341.
  • Coverley D, Laman H, Laskey RA. Distinct roles for cyclins E and A during DNA replication complex assembly and activation. Nat Cell Biol. 2002;4:523–528.
  • Lukasik A, Uniewicz KA, Kulis M, et al. Ciz1, a p21 cip1/Waf1-interacting zinc finger protein and DNA replication factor, is a novel molecular partner for human enhancer of rudimentary homolog. FEBS J. 2008;275:332–340.