The positive circadian regulators CLOCK and BMAL1 control G2/M cell cycle transition through Cyclin B1

References

• Takahashi JS, Hong HK, Ko CH, et al. The genetics of mammalian circadian order and disorder: implications for physiology and disease. Nat Rev Genet. 2008;9:764–775.
   PubMed Web of Science ®Google Scholar
• Mohawk JA, Green CB, Takahashi JS. Central and peripheral circadian clocks in mammals. Annu Rev Neurosci. 2012;35:445–462.
   PubMed Web of Science ®Google Scholar
• Gallego M, Virshup DM. Post-translational modifications regulate the ticking of the circadian clock. Nat Rev Mol Cell Biol. 2007;8:139–148.
   PubMed Web of Science ®Google Scholar
• Stojkovic K, Wing SS, Cermakian N. A central role for ubiquitination within a circadian clock protein modification code. Front Mol Neurosci. 2014;10:3389.
   Google Scholar
• Tyson J, Novak B. Temporal organization of the cell cycle. Curr Biol. 2008;18:R759–R768.
   PubMed Web of Science ®Google Scholar
• Gérard C, Goldbeter A. Temporal self-organization of the cyclin/Cdk network driving the mammalian cell cycle. Proc Natl Acad Sci USA. 2009;106:21643–21648.
   PubMed Web of Science ®Google Scholar
• Henley SA, Dick FA. The retinoblastoma family of proteins and their regulatory functions in the mammalian cell division cycle. Cell Div. 2012;7:10.
   PubMed Web of Science ®Google Scholar
• Koff A, Giordano A, Desai D, et al. Formation and activation of a cyclin E-CDK2 complex during the G1 phase of the human cell cycle. Science. 1992;257:1689–1694.
   PubMed Web of Science ®Google Scholar
• Jackson PK, Chevalier S, Philippe M, et al. Early events in DNA replication require cyclin E and are blocked by p21CIP1. J Cell Biol. 1995;130:755–769.
   PubMed Web of Science ®Google Scholar
• Erlandsson F, Linnman C, Ekholm S, et al. A detailed analysis of Cyclin A accumulation at the G1/S border in normal and transformed cells. Exp Cell Res. 2000;295:86–95.
   Web of Science ®Google Scholar
• Coverley D, Laman H, Laskey RA. Distinct roles for cyclins E and A during DNA replication complex assembly and activation. Nat Cell Biol. 2002;4:523–528.
   PubMed Web of Science ®Google Scholar
• Kalaszczynska I, Geng Y, Iino T, et al. Cyclin A is redundant in fibroblasts but essential in hematopoietic and embryonic stem cells. Cell. 2009;138:352–365.
   PubMed Web of Science ®Google Scholar
• Girard F, Strausfeld U, Fernandez A, et al. Cyclin A is required for the onset of DNA replication in mammalian fibroblasts. Cell. 1991;67:1169–1179.
   PubMed Web of Science ®Google Scholar
• Pagano M, Pepperkok R, Verde F, et al. Cyclin A is required at two points in the human cell cycle. EMBO J. 1992;11:961–971.
   PubMed Web of Science ®Google Scholar
• Gavet O, Pines J. Progressive activation of CyclinB1-Cdk1 coordinates entry to mitosis. Dev Cell. 2010;18:533–543.
   PubMed Web of Science ®Google Scholar
• Lindqvist A, Rodriguez-Bravo R, Medema RH. The decision to enter mitosis: feedback and redundancy in the mitotic entry network. Cell Biol. 2009;185:193–202.
   PubMed Web of Science ®Google Scholar
• Fung TK, Poon RYC. A roller coaster ride with the mitotic cyclins. Sem Cell Dev Biol. 2005;16:335–342.
   PubMed Web of Science ®Google Scholar
• Mueller PR, Coleman TR, Kumagai A, et al. Myt1: a membrane-associated inhibitory kinase that phosphorylates Cdc2 on both threonine-14 and tyrosine-15. Science. 1995;270:86–90.
   PubMed Web of Science ®Google Scholar
• Parker LL, Piwnica-Worms H. Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase. Science. 1992;257:1955–1957.
   PubMed Web of Science ®Google Scholar
• Bjarnason GA, Jordan RCK, Sothern RB. Circadian variation in the expression of cell-cycle proteins in human oral epithelium. Am J Pathol. 1999;154:613–622.
   PubMed Web of Science ®Google Scholar
• Bjarnason GA, Jordan RCK, Wood PA, et al. Circadian expression of clock genes in human oral mucosa and skin. Am J Pathol. 2001;158:1793–1801.
   PubMed Web of Science ®Google Scholar
• Matsuo T, Yamaguchi S, Mitsui S, et al. Control mechanism of the circadian clock for timing of cell division in vivo. Science. 2003;302:255–259.
   PubMed Web of Science ®Google Scholar
• Gréchez-Cassiau A, Rayet B, Guillaumond F, et al. The circadian clock component BMAL1 is a critical regulator of p21WAF1/CIP1 expression and hepatocyte proliferation. J Biol Chem. 2008;283:4535–4542.
   PubMed Web of Science ®Google Scholar
• Kowalska E, Ripperger JA, Hoegger DC, et al. NONO couples the circadian clock to the cell cycle. Proc Natl Acad Sci USA. 2013;110:1592–1599.
   PubMed Web of Science ®Google Scholar
• Zhao X, Hirota T, Han X, et al. Circadian amplitude regulation via FBXW7-targeted REV-ERBα degradation. Cell. 2016;165:1644–1657.
   PubMed Web of Science ®Google Scholar
• Nagoshi E, Saini C, Bauer C, et al. Circadian gene expression in individual fibroblasts: cell-autonomous and self-sustained oscillators pass time to daughter cells. Cell. 2004;119:693–705.
   PubMed Web of Science ®Google Scholar
• Bieler J, Cannavo R, Gustafson K, et al. Robust synchronization of coupled circadian and cell cycle oscillators in single mammalian cells. Mol Syst Biol. 2014;10:739.
   PubMed Web of Science ®Google Scholar
• Feillet C, Krusche P, Tamanini F, et al. Phase locking and multiple oscillating attractors for the coupled mammalian clock and cell cycle. Proc Natl Acad Sci USA. 2014;111:9828–9833.
   PubMed Web of Science ®Google Scholar
• Leloup JC, Goldbeter A. Toward a detailed computational model for the mammalian circadian clock. Proc Natl Acad Sci USA. 2003;110:7051–7056.
   Web of Science ®Google Scholar
• Leloup JC, Goldbeter A. Modeling the mammalian circadian clock: sensitivity analysis and multiplicity of oscillatory mechanisms. J Theor Biol. 2004;230:541–562.
   PubMed Web of Science ®Google Scholar
• Gérard C, Goldbeter A. The balance between cell cycle arrest and cell proliferation: control by the extracellular matrix and by contact inhibition. Interface Focus. 2014;4:20130075.
   PubMed Web of Science ®Google Scholar
• Gérard C, Goldbeter A. Entrainment of the mammalian cell cycle by the circadian clock: modeling two coupled cellular rhythms. PLoS Comput Biol. 2012;8:e1002516.
   PubMed Web of Science ®Google Scholar
• Traynard P, Feillet C, Soliman S, et al. Model-based investigation of the circadian clock and cell cycle coupling in mouse embryonic fibroblasts: prediction of RevErb-α up-regulation during mitosis. Biosystems. 2016;149:59–69.
   PubMed Web of Science ®Google Scholar
• Paijmans J, Bosman M, Ten Wolde PR, et al. Discrete gene replication events drive coupling between the cell cycle and circadian clocks. Proc Natl Acad Sci USA. 2016;113:4063–4068.
   PubMed Web of Science ®Google Scholar
• Cogswell JP, Godlevski MM, Bonham M, et al. Upstream stimulatory factor regulates expression of the cell cycle-dependent cyclin B1 gene promoter. Mol Cell Biol. 1995;15:2782–2790.
   PubMed Web of Science ®Google Scholar
• Wasner M, Tschöp K, Spiesbach K, et al. Cyclin B1 transcription is enhanced by the p300 coactivator and regulated during the cell cycle by a CHR-dependent repression mechanism. FEBS Lett. 2003;536:66–70.
   PubMed Web of Science ®Google Scholar
• Gao XN, Lin J, Ning QY, et al. A histone acetyltransferase p300 inhibitor C646 induces cell cycle arrest and apoptosis selectively in AML1-ETO-positive AML cells. PLoS One. 2013;8:e55481.
   PubMed Web of Science ®Google Scholar
• Yan G, Eller MS, Elm C, et al. Selective inhibition of p300 HAT blocks cell cycle progression, induces cellular senescence, and inhibits the DNA damage response in melanoma cells. J Invest Dermatol. 2013;133:2444–2452.
   PubMed Web of Science ®Google Scholar
• Mullenders J, Fabius AW, Madiredjo M, et al. A large scale shRNA barcode screen identifies the circadian clock component ARNTL as putative regulator of the p53 tumor suppressor pathway. PLoS One. 2009;4:e4798.
   PubMed Web of Science ®Google Scholar
• Jiang W, Zhao S, Jiang X, et al. The circadian clock gene Bmal1 acts as a potential anti-oncogene in pancreatic cancer by activating the p53 tumor suppressor pathway. Cancer Lett. 2016;371:314–325.
   PubMed Web of Science ®Google Scholar
• Innocente SA, Abrahamson JLA, Cogswell JP, et al. p53 regulates a G2 checkpoint through Cyclin B1. Proc Natl Acad Sci USA. 1999;96:2147–2152.
   PubMed Web of Science ®Google Scholar
• Gotoh T, Kim JK, Liu J, et al. Model-driven experimental approach reveals the complex regulatory distribution of p53 by the circadian factor Period 2. Proc Natl Acad Sci USA. 2016;113:13516–13521.
   PubMed Web of Science ®Google Scholar
• Bouchard-Cannon P, Mendoza-Viveros L, Yuen A, et al. The circadian molecular clock regulates adult hippocampal neurogenesis by controlling the timing of cell-cycle entry and exit. Cell Rep. 2013;5:961–973.
   PubMed Web of Science ®Google Scholar
• Androic I, Krämer A, Yan R, et al. Targeting cyclin B1 inhibits proliferation and sensitizes breast cancer cells to taxol. BMC Cancer. 2008;8:391.
   PubMed Web of Science ®Google Scholar