Mapping metabolic oscillations during cell cycle progression

References

• Hopkins AL, Groom CR. The druggable genome. Nat Rev Drug Discov. 2002;1:727–730.
   PubMed Web of Science ®Google Scholar
• Wilson PM, Danenberg PV, Johnston PG, et al. Standing the test of time: targeting thymidylate biosynthesis in cancer therapy. Nat Rev Clin Oncol. Nature Publishing Group. 2014;11: 282–298.
   PubMed Web of Science ®Google Scholar
• Kim DJ, Roh E, Lee M-H, et al. Herbacetin is a novel allosteric inhibitor of ornithine decarboxylase with antitumor activity. Cancer Res. NIH Public Access. 2016;76:1146.
   PubMed Web of Science ®Google Scholar
• Reichard P. Interactions between deoxyribonucleotide and DNA synthesis. Ann Rev Biochem. 1988;57:349–374.
   PubMed Web of Science ®Google Scholar
• Fredlund JO, Johansson MC, Dahlberg E, et al. Ornithine decarboxylase and S-adenosylmethionine decarboxylase expression during the cell cycle of Chinese hamster ovary cells. Exp Cell Res. 1995;216:86–92.
   PubMed Web of Science ®Google Scholar
• Taylor JH. Nucleic acid synthesis in relation to the cell division cycle. Ann N Y Acad Sci. 1960;90:409–421.
   PubMed Web of Science ®Google Scholar
• Rousset M, Chevalier G, Rousset J-P, et al. Presence and cell growth-related variations of glycogen in human colorectal adenocarcinoma cell lines in culture. Cancer Res. 1979;39:531–534.
   PubMed Web of Science ®Google Scholar
• Vizán P, Alcarraz-Vizán G, Díaz-Moralli S, et al. Modulation of pentose phosphate pathway during cell cycle progression in human colon adenocarcinoma cell line HT29. Int J Cancer. Wiley Subscription Services, Inc., A Wiley Company. 2009;124: 2789–2796.
   PubMed Web of Science ®Google Scholar
• Ahn E, Kumar P, Mukha D, et al. Temporal fluxomics reveals oscillations in TCA cycle flux throughout the mammalian cell cycle. Mol Syst Biol. 2017;13:953.
   Web of Science ®Google Scholar
• Mitchison JM. Growth during the cell cycle. Int Rev Cytol. 2003;226:165–258.
   PubMedGoogle Scholar
• Ginzberg MB, Kafri R, Kirschner M. On being the right (cell) size. Science. 2015;348(80):1245075.
   PubMedGoogle Scholar
• Roci I, Gallart-Ayala H, Schmidt A, et al. Metabolite profiling and stable isotope tracing in sorted subpopulations of mammalian cells. Anal Chem. 2016;88:2707–2713
   PubMed Web of Science ®Google Scholar
• Roci I, Watrous JD, Lagerborg KA, et al. Mapping metabolic events in the cancer cell cycle reveals arginine catabolism in the committed SG2M phase. Cell Rep. 2019;26:1691–1700. e5.
   PubMed Web of Science ®Google Scholar
• Whitfield ML, Sherlock G, Saldanha AJ, et al. Identification of genes periodically expressed in the human cell cycle and their expression in tumors. Mol Biol Cell. 2002;13:1977–2000.
   PubMed Web of Science ®Google Scholar
• Wishart DS, Jewison T, Guo AC, et al. HMDB 3.0–The human metabolome database in 2013. Nucleic Acids Res. 2013;41:D801–7.
   PubMed Web of Science ®Google Scholar
• Toettcher JE, Loewer A, Ostheimer GJ, et al. Distinct mechanisms act in concert to mediate cell cycle arrest. Proc Natl Acad Sci. 2009;106:785–790.
   PubMed Web of Science ®Google Scholar
• Tzur A, Moore JK, Jorgensen P, et al. Optimizing optical flow cytometry for cell volume-based sorting and analysis. PLoS One Public Lib Sci. 2011;6:e16053.
   PubMed Web of Science ®Google Scholar
• Grant GD, Brooks L, Zhang X, et al. Identification of cell cycle-regulated genes periodically expressed in U2OS cells and their regulation by FOXM1 and E2F transcription factors. Mol Biol Cell. 2013;24:3634–3650.
   PubMed Web of Science ®Google Scholar
• Son S, Tzur A, Weng Y, et al. Direct observation of mammalian cell growth and size regulation. Nat Methods. Nat Res. 2012;9:910–912.
   PubMed Web of Science ®Google Scholar
• Bray G, Brent TP. Deoxyribonucleoside 5ʹ-triphosphate pool fluctuations during the mammalian cell cycle. Biochim Biophys Acta. 1972;269:184–191.
   PubMedGoogle Scholar
• Skoog KL, Nordenskjold BA, Bjursell KG. Deoxyribonucleoside-triphosphate pools and DNA synthesis in synchronized hamster cells. Eur J Biochem. Blackwell Publishing Ltd. 1973;33:428–432.
   PubMedGoogle Scholar
• Fasullo M, Endres L. Nucleotide salvage deficiencies, DNA damage and neurodegeneration. Int J Mol Sci. Multidisciplinary Digital Publishing Institute (MDPI). 2015;16:9431–9449.
   PubMed Web of Science ®Google Scholar
• Berdis AJ. Mechanisms of DNA Polymerases. Chem Rev. 2009;109:2862–2879.
   PubMed Web of Science ®Google Scholar
• Atkinson DE. Energy charge of the adenylate pool as a regulatory parameter. Interaction with feedback modifiers. Biochem. American Chemical Society. 1968;7:4030–4034.
   PubMed Web of Science ®Google Scholar
• Marcussen M, Larsen PJ. Cell cycle-dependent regulation of cellular ATP concentration, and depolymerization of the interphase microtubular network induced by elevated cellular ATP concentration in whole fibroblasts. Cell Motil Cytoskeleton. 1996;35:94–99.
   PubMed Web of Science ®Google Scholar
• Szekeres T, Fritzer M, Pillwein K, et al. Cell cycle dependent regulation of IMP dehydrogenase activity and effect of tiazofurin. Life Sci. 1992;51:1309–1315.
   PubMed Web of Science ®Google Scholar
• Thomas KC, Dawson PS. Variations in the adenylate energy charge during phased growth (cell cycle) of Candida utilis under energy excess and energy-limiting growth conditions. J Bacteriol. 1977;132:36–43.
   PubMed Web of Science ®Google Scholar
• Dickinson JR. Nucleoside diphosphokinase and cell cycle control in the fission yeast Schizosaccharomyces pombe. J Cell Sci. 1983;60:355–365.
   PubMed Web of Science ®Google Scholar
• Atkinson DE. Interactions between Regulatory Parameters. Cell Energy Metab Regul. Elsevier. 1977. p. 175–200.
   Google Scholar
• Sun X, Zhang N, Li K, et al. Branched chain amino acid imbalance selectively inhibits the growth of gastric carcinoma cells in vitro. Nutr Res. Elsevier. 2003;23:1279–1290.
   Web of Science ®Google Scholar
• Jones SM, Kazlauskas A. Growth-factor-dependent mitogenesis requires two distinct phases of signalling. Nat Cell Biol. Nature Publishing Group. 2001;3:165–172.
   PubMed Web of Science ®Google Scholar
• Clarke JH, Letcher AJ, D ’Santos CS, et al. Inositol lipids are regulated during cell cycle progression in the nuclei of murine erythroleukaemia cells. Biochem J. 2001;357:905–910.
   PubMed Web of Science ®Google Scholar
• York JD, Majerus PW. Nuclear phosphatidylinositols decrease during s-phase of the cell cycle in hela cells*. J Biowcical Chem. 1994;269:7847–7850.
   Web of Science ®Google Scholar
• Mahieu NG, Patti GJ. Systems-level annotation of a metabolomics data set reduces 25 000 features to fewer than 1000 unique metabolites. Anal Chem. American Chemical Society. 2017;89:10397–10406.
   PubMed Web of Science ®Google Scholar
• Guijas C, Montenegro-Burke JR, Domingo-Almenara X, Palermo A, Warth B, Hermann G, et al. METLIN: a technology platform for identifying knowns and unknowns. Anal Chem. 2018;90:3156–3164.
   PubMed Web of Science ®Google Scholar
• Grankvist N, Watrous JD, Lagerborg KA, et al. Profiling the metabolism of human cells by deep 13C labeling. Cell Chem Biol. 2018;25:1419–1427. e4.
   PubMed Web of Science ®Google Scholar
• Kang Y, Edwards LG, Thornalley PJ. Effect of methylglyoxal on human leukaemia 60 cell growth: modification of DNA, G1 growth arrest and induction of apoptosis. Leuk Res. 1996;20:397–405.
   PubMed Web of Science ®Google Scholar
• Kani S, Nakayama E, Yoda A, et al. Chk2 kinase is required for methylglyoxal-induced G 2/M cell-cycle checkpoint arrest: implication of cell-cycle checkpoint regulation in diabetic oxidative stress signaling. Genes Cells. 2007;12:919–928.
   PubMed Web of Science ®Google Scholar
• Braun JD, Pastene DO, Breedijk A, et al. Methylglyoxal down-regulates the expression of cell cycle associated genes and activates the p53 pathway in human umbilical vein endothelial cells. Sci Rep. 2019;9:1152.
   PubMedGoogle Scholar
• Lyutvinskiy Y, Watrous JD, Jain M, et al. A web service framework for interactive analysis of metabolomics data. Anal Chem. 2017;89:5713–5718.
   PubMed Web of Science ®Google Scholar
• Wang M, Carver JJ, Phelan VV, et al. Sharing and community curation of mass spectrometry data with global natural products social molecular networking. Nat Biotechnol. 2016;34:828–837.
   PubMed Web of Science ®Google Scholar