1,230
Views
6
CrossRef citations to date
0
Altmetric
Research Paper

RNAi-mediated knockdown of PFK1 decreases the invasive capability and metastasis of nasopharyngeal carcinoma cell line, CNE-2

, , , , , , , , , , , & ORCID Icon show all
Pages 154-165 | Received 24 Jun 2020, Accepted 11 Dec 2020, Published online: 06 Jan 2021

References

  • Chen YP, Chan ATC, Le QT, et al. Nasopharyngeal carcinoma. Lancet. 2019;394:64–80.
  • Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68:394–424.
  • Chen M, Tang LL, Sun Y, et al. Treatment outcomes and feasibility of partial neck irradiation for patients with nasopharyngeal carcinoma with only retropharyngeal lymph node metastasis after intensity-modulated radiotherapy. Head Neck. 2014;36:468–473.
  • M F J, Sheng W, Cheng W, et al. Incidence and mortality of nasopharyngeal carcinoma: interim analysis of a cluster randomized controlled screening trial (PRO-NPC-001) in southern China. Ann Oncol. 2019;30:1630–1637.
  • Wang JY, Li XF, Li PZ, et al. MicroRNA-23b regulates nasopharyngeal carcinoma cell proliferation and metastasis by targeting E-cadherin. Mol Med Rep. 2016;14:537–543.
  • He HL, Lee YE, Liang PI, et al. Overexpression of JAK2: a predictor of unfavorable prognosis for nasopharyngeal carcinoma. Future Oncol. 2016;12:1887–1896.
  • Sun CM, Xiong DB, Yan Y, et al. Genetic alteration in phospho fructokinase family promotes growth of muscle-invasive bladder cancer. Int J Biol Markers. 2016;31:286–293.
  • Alfarouk KO, Verduzco D, Rauch C, et al. Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer question. Oncoscience. 2014;1:777–802.
  • Amano Y, Mandai M, Yamaguchi K, et al. Metabolic alterations caused by HNF1β expression in ovarian clear cell carcinoma contribute to cell survival. Oncotarget. 2015;6:26002–26017.
  • MorenoSánchez R, RodríguezEnríquez S, MarínHerná- ndez A, et al. Energy metabolism in tumor cells. Febs J. 2010;274:1393–1418.
  • Xiang JD, Zhou LN, Zhuang Y, et al. Lactate dehydrogenase is correlated with clinical stage and grade and is downregulated by si-STAB1 in ovarian cancer. Oncol Rep. 2018;40:2788–2797.
  • Fujiwara H, Tateishi K, Misumi K, et al. Effect of high glucose on expression of glycolytic enzymes in cholangiocarcinoma cells. Sci Rep. 2019;9:18859.
  • Cui SS, Yang X, Zhang LH, et al. LncRNA MAFG-AS1 promotes the progression of colorectal cancer by sponging miR-147b and activation of NDUFA4. Biochem Biophys Res Commun. 2018;506:251–258.
  • Lee JH, Liu R, Li J, et al. EGFR-phosphorylated platelet isoform of phosphofructokinase 1 promotes PI3K activation. Mol Cell. 2018;70:197–210.
  • Yalcin A, Clem BF, Imbert-Fernandez Y, et al. 6-Phosphofructo-2-kinase (PFKFB3) promotes cell cycle progression and suppresses apoptosis via Cdk1-mediated phosphorylation of p27. Cell Death Dis. 2014;5:e1337.
  • Smerc A, Sodja E, Legisa M. Posttranslational modification of 6-phosphofructo-1-kinase as an important feature of cancer metabolism. PloS One. 2011;6:e19645.
  • Donato L, D’Angelo R, Alibrandi S, et al. Effects of A2E-induced oxidative stress on retinal epithelial cells: new insights on differential gene response and retinal dystrophies. Antioxidants. 2020;9:307.
  • Jia W, Ren C, Wang L, et al. CD109 is identified as a potential nasopharyngeal carcinoma biomarker using aptamer selected by cell-SELEX. Oncotarget. 2016;7:55328–55342.
  • Li Y, Tang X, He Q, et al. Overexpression of mitochondria mediator gene TRIAP1 by miR-320b loss is associated with progression in nasopharyngeal carcinoma. PLoS Genet. 2016;12:e1006183.
  • Siti-Azrin AH, Norsa’adah B, Naing NN. Five-year survival and median survival time of nasopharyngeal carcinoma in hospital universiti Sains Malaysia. Asian Pac J Cancer Prev. 2014;15:6455–6459.
  • Szturz P, Vermorken JB. Immunotherapy in head and neck cancer: aiming at EXTREME precision. BMC Med. 2017;15:110.
  • Lee N, Harris J, Pfister DG, et al. Long-term update of a phase II Study of concurrent chemoradiotherapy using radiation + bevacizumab (BV) for locally or regionally advanced nasopharyngeal cancer (NPC): RTOG 0615. Int J Radiat Oncol Biol Phys. 2020;106:1119.
  • Yi W, Clark PM, Mason DE, et al. PFK1 glycosylation is a key regulator of cancer cell growth and central metabolic pathways. Science. 2012;337:975–980.
  • Wang S, Peng Z, Wang S, et al. Author Correction: KRAB-type zinc-finger proteins PITA and PISA specifically regulate p53-dependent glycolysis and mitochondrial respiration. Cell Res Cell Res. 2018;28:605.
  • Yang Y, Ishak Gabra MB, Hanse EA, et al. MiR-135 suppresses glycolysis and promotes pancreatic cancer cell adaptation to metabolic stress by targeting phosphofructokinase-1. Nat Commun. 2019;10:809.
  • Altenberg B, Greulich KO. Genes of glycolysis are ubiquitously overexpressed in 24 cancer classes. Genomics. 2004;84:1014–1020.
  • Glunde K, Jiang L, Moestue SA, et al. Magnetic resonance spectroscopy and imaging guidance in molecular medicine: targeting and monitoring of choline and glucose metabolism in cancer. NMR Biomed. 2011;24:673–690.
  • Tatiana EB, Marta SF, Mauro SP. Cellular distribution of phosphofructokinase activity and implications to metabolic regulation in human breast cancer. Mol Genet Metab. 2003;79:294–299.
  • Ambros V. A hierarchy of regulatory genes controls a larva-to-adult developmental switch in C. elegans. Cell. 1989;57:49–57.
  • Gui SJ, Ding RL, Wan YP, et al. Knockdown of annexin VII enhances nasopharyngeal carcinoma cell radiosensitivity in vivo and in vitro. Cancer Biomark. 2020;28:129–139.
  • Donato L, Scimone C, Alibrandi S, et al. Transcriptome analyses of lncRNAs in A2E-stressed retinal epithelial cells unveil advanced links between metabolic impairments related to oxidative stress and retinitis pigmentosa. Antioxidants. 2020;9:318.
  • Donato L, Scimone C, Alibrandi S, et al. Discovery of GLO1 new related genes and pathways by RNA-Seq on A2E-stressed retinal epithelial cells could improve knowledge on retinitis pigmentosa. Antioxidants. 2020;9:416.
  • Rinaldi C, Bramanti P, Scimone C, et al. Relevance of CCM gene polymorphisms for clinical management of sporadic cerebral cavernous malformations. J Neurol Sci. 2017;380:31–37.
  • Donato L, Bramanti P, Scimone C, et al. miRNA expression profile of retinal pigment epithelial cells under oxidative stress conditions. Wiley-Blackwell Online Open. 2018;8:219–233.
  • Zhou J, Luo Y-H, Wang J-R, et al. Gambogenic acid induction of apoptosis in a breast cancer cell line. Asian Pac J Cancer Prev Apjcp. 2013;14(12):7601–7605.
  • Reed JC. Double identity for proteins of the Bcl-2 family. Nature. 1997;387:773–776.
  • Francesca M, Condelli V, Valentina DS, et al. TRAP1 enhances Warburg metabolism through modulation of PFK1 expression/activity and favors resistance to EGFR inhibitors in human colorectal carcinomas. Mol Oncol. 2020 Oct 6. Online ahead of print. DOI:10.1002/1878-0261.12814.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.