Circular RNA PGPEP1 induces colorectal cancer malignancy and immune escape

References

• Siegel R, Miller KD, Fuchs HE, et al. Cancer statistics, 2021. Ca A Cancer J Clinicians. 2021;71(1):7–33. DOI:10.3322/caac.21654
   PubMed Web of Science ®Google Scholar
• Arnold M, Sierra MS, Laversanne M, et al. Global patterns and trends in colorectal cancer incidence and mortality. Gut. 2017;66(4):683–691. DOI:10.1136/gutjnl-2015-310912
   PubMed Web of Science ®Google Scholar
• Liu Y, Xu H-F, Zhang X, et al. Disease knowledge, medical experience, health-related quality of life and health-care costs among patients with advanced colorectal cancer in China: protocol for a nationwide multicentre survey. BMJ Open. 2022;12(3):e054403. DOI:10.1136/bmjopen-2021-054403
   PubMed Web of Science ®Google Scholar
• Zhu Y, Li J, Liu H, et al. Circular RNA, hsa_circRNA_102049, promotes colorectal cancer cell migration and invasion via binding and suppressing miRNA‑455‑3p. Exp Ther Med. 2022;23(3):244. DOI:10.3892/etm.2022.11169
   PubMed Web of Science ®Google Scholar
• Hanahan D, Weinberg R. Hallmarks of cancer: the next generation. Cell. 2011;144(5):646–674. doi:10.1016/j.cell.2011.02.013.
   PubMed Web of Science ®Google Scholar
• Chen Q, Hong Y, Weng S, et al. Traditional Chinese medicine pien-tze-huang inhibits colorectal cancer growth and immune evasion by reducing β-catenin transcriptional activity and PD-L1 expression. Front Pharmacol. 2022;13:828440. doi:10.3389/fphar.2022.828440
   PubMed Web of Science ®Google Scholar
• Ebbesen K, Hansen T, Kjems J. Insights into circular RNA biology. RNA biology. RNA Biol. 2017;14(8):1035–1045. doi:10.1080/15476286.2016.1271524.
   PubMed Web of Science ®Google Scholar
• Zhang S, Sun J, Gu M, et al. Circular RNA: a promising new star for the diagnosis and treatment of colorectal cancer. Cancer Med. 2021;10(24):8725–8740. DOI:10.1002/cam4.4398
   PubMed Web of Science ®Google Scholar
• Jiang Z, Hou Z, Liu W, et al. Circular RNA protein tyrosine kinase 2 (circPTK2) promotes colorectal cancer proliferation, migration, invasion and chemoresistance. Bioengineered. 2022;13(1):810–823. DOI:10.1080/21655979.2021.2012952
   PubMed Web of Science ®Google Scholar
• Jiang Z, Hou Z, Liu W, et al. Circ-keratin 6c promotes malignant progression and immune evasion of colorectal cancer through microRNA-485-3p/Programmed cell death receptor ligand 1 axis. J Pharmacol Exp Ther. 2021;377(3):358–367. DOI:10.1124/jpet.121.000518
   PubMed Web of Science ®Google Scholar
• Aghanoori M, Mirzaei B, Tavallaei M. MiRNA molecular profiles in human medical conditions: connecting lung cancer and lung development phenomena. Asian Pac J Cancer Prev. 2014;15(22):9557–9565. doi:10.7314/APJCP.2014.15.22.9557.
   PubMedGoogle Scholar
• Ameli-Mojarad M, Ameli-Mojarad M, Hadizadeh M, et al. The effective function of circular RNA in colorectal cancer. Cancer Cell Int. 2021;21(1):496. DOI:10.1186/s12935-021-02196-0
   PubMed Web of Science ®Google Scholar
• Ding X, Fu Q, Chen W, et al. Targeting of MAD2L1 by miR-515-5p involves the regulation of cell cycle arrest and apoptosis of colorectal cancer cells. Cell Biol Int. 2022;46(5):840–848. DOI:10.1002/cbin.11774
   PubMed Web of Science ®Google Scholar
• Mao G, Zhou B, Xu W, et al. Hsa_circ_0040809 regulates colorectal cancer development by upregulating methyltransferase DNMT1 via targeting miR-515-5p. J Gene Med. 2021;23(12):e3388. DOI:10.1002/jgm.3388
   PubMed Web of Science ®Google Scholar
• Müller M, Rao A. NFAT, immunity and cancer: a transcription factor comes of age. Nature RevImmunology. 2010;10(9):645–656. doi:10.1038/nri2818.
   Web of Science ®Google Scholar
• Wang D, Xu Y, Tu Y-L, et al. Comparison analysis in synchronous and metachronous metastatic colorectal cancer based on microarray expression profile. Hepatogastroenterology. 2014;61(136):2215–2218.
   PubMedGoogle Scholar
• Shi H, Li H, Zhen T, et al. Hsa_circ_001653 implicates in the development of pancreatic ductal adenocarcinoma by regulating MicroRNA-377-mediated HOXC6 Axis. Mol Ther Nucleic Acids. 2020;20:252–264. doi:10.1016/j.omtn.2019.12.028
   PubMedGoogle Scholar
• Yu J, Xu Q-G, Wang Z-G, et al. Circular RNA cSMARCA5 inhibits growth and metastasis in hepatocellular carcinoma. J Hepatol. 2018;68(6):1214–1227. DOI:10.1016/j.jhep.2018.01.012
   PubMed Web of Science ®Google Scholar
• Jia L, Wang Y, Wang C. circFAT1 promotes cancer stemness and immune evasion by promoting STAT3 activation. Adv Sci (Weinheim, Baden-Wurttemberg, Germany). 2021;8(13):2003376. doi:10.1002/advs.202003376.
   PubMedGoogle Scholar
• Mun JG, Jeon HD, Yoon DH, et al. Supercritical extract of cannabis sativa inhibits lung metastasis in colorectal cancer cells by increasing AMPK and mAPKs-mediated apoptosis and cell cycle arrest. Nutrients. 2022;14(21):14(21. DOI:10.3390/nu14214548
   Web of Science ®Google Scholar
• Ji Y, Zhao Q, Feng W, et al. N6-methyladenosine modification of CIRCKRT17 initiated by METTL3 promotes osimertinib resistance of lung adenocarcinoma by EIF4A3 to enhance YAP1 stability. Cancers (Basel). 2022;14(22):14(22. DOI:10.3390/cancers14225582
   Web of Science ®Google Scholar
• Jiang Y, Zhao J, Li R, et al. CircLRFN5 inhibits the progression of glioblastoma via PRRX2/GCH1 mediated ferroptosis. J Exp Clin Cancer Res. 2022;41(1):307. DOI:10.1186/s13046-022-02518-8
   PubMed Web of Science ®Google Scholar
• Lu H, Shi T, Wang M, et al. B7-H3 inhibits the IFN-γ-dependent cytotoxicity of Vγ9Vδ2 T cells against colon cancer cells. Oncoimmunology. 2020;9(1):1748991. DOI:10.1080/2162402X.2020.1748991
   PubMed Web of Science ®Google Scholar
• Jin D, Fan J, Wang L, et al. CD73 on tumor cells impairs antitumor T-cell responses: a novel mechanism of tumor-induced immune suppression. Cancer Res. 2010;70(6):2245–2255. DOI:10.1158/0008-5472.CAN-09-3109
   PubMed Web of Science ®Google Scholar
• Xu Y, Dong Z-N, Wang S-W, et al. circHMGCS1–016 reshapes immune environment by sponging miR-1236-3p to regulate CD73 and GAL-8 expression in intrahepatic cholangiocarcinoma. J Exp Clin Cancer Res. 2021;40(1):290. DOI:10.1186/s13046-021-02095-2
   PubMed Web of Science ®Google Scholar
• Hsieh CH, Tai SK, Yang MH. Snail-overexpressing cancer cells promote M2-like polarization of tumor-associated macrophages by delivering miR-21-abundant exosomes. Neoplasia. 2018;20(8):775–788. doi:10.1016/j.neo.2018.06.004.
   PubMed Web of Science ®Google Scholar
• He Y, Han P, Chen C, et al. circPTPN22 attenuates immune microenvironment of pancreatic cancer via STAT3 acetylation. Cancer Genet Ther. 2021;30(4):559–566. DOI:10.1038/s41417-021-00382-w
   PubMed Web of Science ®Google Scholar
• Hong W, Xue M, Jiang J, et al. Circular RNA circ-cPA4/let-7 miRNA/PD-L1 axis regulates cell growth, stemness, drug resistance and immune evasion in non-small cell lung cancer (NSCLC). J Exp Clin Cancer Res. 2020;39(1):149. DOI:10.1186/s13046-020-01648-1
   PubMed Web of Science ®Google Scholar
• Yang J, Hao R, Zhang Y, et al. Construction of circRNA-miRNA-mRNA network and identification of novel potential biomarkers for non-small cell lung cancer. Cancer Cell Int. 2021;21(1):611. DOI:10.1186/s12935-021-02278-z
   PubMed Web of Science ®Google Scholar
• Viralippurath Ashraf J, Sasidharan Nair V, Saleh R, et al. Role of circular RNAs in colorectal tumor microenvironment. Biomed Pharmacother. 2021;137:111351. doi:10.1016/j.biopha.2021.111351
   PubMed Web of Science ®Google Scholar
• Feng Z, Li L, Tu Y, et al. Identification of circular RNA-Based immunomodulatory networks in colorectal cancer. frontiers in oncology, 2021. Front Oncol. 2022;11:779706. doi:10.3389/fonc.2021.779706
   PubMed Web of Science ®Google Scholar
• Feng N, Jiao Z, Zhang Y, et al. Hsa_circ_0050102 regulates the pancreatic cancer development via miR-218-5p/PPME1 axis. J Clin Lab Analysis. 2022;36(3):e24247. DOI:10.1002/jcla.24247
   PubMed Web of Science ®Google Scholar
• Wang Y, Liu X, Wang L, et al. Circ_pgpep1 serves as a sponge of miR-1297 to promote gastric cancer progression via regulating E2F3. digestive diseases and sciences. Dig Dis Sci. 2021;66(12):4302–4313. DOI:10.1007/s10620-020-06783-5
   PubMed Web of Science ®Google Scholar
• Gao C, Xu Y-J, Qi L, et al. CircRNA VIM silence synergizes with sevoflurane to inhibit immune escape and multiple oncogenic activities of esophageal cancer by simultaneously regulating miR-124/PD-L1 axis. Cell Biol Toxicol. 2021;38(5):825–845. DOI:10.1007/s10565-021-09613-0
   PubMed Web of Science ®Google Scholar
• Yang J, Jia Y, Wang B, et al. Circular RNA CHST15 sponges miR-155-5p and miR-194-5p to promote the immune escape of lung cancer cells mediated by PD-L1. Front Oncol. 2021;11:595609. doi:10.3389/fonc.2021.595609
   PubMed Web of Science ®Google Scholar
• Baudoux T, Husson C, De Prez E, et al. CD4 and CD8 T Cells Exert Regulatory properties during experimental acute aristolochic acid nephropathy. Sci Rep. 2018;8(1):5334. DOI:10.1038/s41598-018-23565-2
   PubMedGoogle Scholar
• Yin Y, Long J, He Q, et al. Emerging roles of circRNA in formation and progression of cancer. J Cancer. 2019;10(21):5015–5021. DOI:10.7150/jca.30828
   PubMed Web of Science ®Google Scholar
• Adams B, Kasinski A, Slack F. Aberrant regulation and function of microRnas in cancer. Curr Biol. 2014;24(16):R762–76. doi:10.1016/j.cub.2014.06.043.
   PubMed Web of Science ®Google Scholar
• Wang L, Hou S, Li J, et al. Circular RNA circ-LARP1B contributes to cutaneous squamous cell carcinoma progression by targeting microRNA-515-5p/TPX2 microtubule nucleation factor axis. Bioengineered. 2022;13(1):1209–1223. DOI:10.1080/21655979.2021.2019172
   PubMed Web of Science ®Google Scholar
• Shi P, Li Y, Guo Q. Circular RNA circPIP5K1A contributes to cancer stemness of osteosarcoma by miR-515-5p/YAP axis. J Transl Med. 2021;19(1):464. doi:10.1186/s12967-021-03124-6.
   PubMed Web of Science ®Google Scholar
• Ma T, Li H, Yang W, et al. Over-expression of miR-193a-3p regulates the apoptosis of colorectal cancer cells by targeting PAK3. Am J Transl Res. 2022;14(2):1361–1375.
   PubMed Web of Science ®Google Scholar
• Lee N, Kim D, Kim W. Role of NFAT5 in the immune system and pathogenesis of autoimmune diseases. Front Immunol. 2019;10:270. doi: 10.3389/fimmu.2019.00270
   PubMedGoogle Scholar
• Fu S, Zhang Y, Li S, et al. LncRNA TTN-AS1 promotes the progression of oral squamous cell carcinoma via miR-411-3p/NFAT5 axis. Cancer Cell Int. 2020;20(1):415. DOI:10.1186/s12935-020-01378-6
   PubMed Web of Science ®Google Scholar
• Dou Y, Tian W, Wang H, et al. Circ_0001944 contributes to glycolysis and tumor growth by upregulating NFAT5 through acting as a decoy for miR-142-5p in non-small cell lung cancer. Cancer Manage Res. 2021;13:3775–3787. doi:10.2147/CMAR.S302814
   PubMed Web of Science ®Google Scholar
• Qin X, Li C, Guo T, et al. Upregulation of DARS2 by HBV promotes hepatocarcinogenesis through the miR-30e-5p/MAPK/NFAT5 pathway. J Exp Clin Cancer Res. 2017;36(1):148. DOI:10.1186/s13046-017-0618-x
   PubMedGoogle Scholar
• Zhang S, Liao K, Miao Z, et al. CircFOXO3 promotes glioblastoma progression by acting as a competing endogenous RNA for NFAT5. Neuro Oncol. 2019;21(10):1284–1296. DOI:10.1093/neuonc/noz128
   PubMed Web of Science ®Google Scholar