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Research Article

Adhesion of Monocytes to Medical Steel as Used for Vascular Stents is Mediated by the Integrin Receptor Mac-1 (CD11b/CD18; α M β 2 ) and Can be Inhibited by Semiconductor Coating

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Pages 17-26 | Published online: 11 Jul 2009

  • Altieri DC, Edgington TS (1988). A monoclonal antibody reacting with distinct adhesion molecules defines a transition in the functional state of the receptor CD11b/CD18 (Mac-1). J Immunol 141:2656-2660.
  • Bayer G, Hartwig S, Nagel M, Tittelbach M, Rzany A, Schaldach M (2001). Future strategies for antiproliferative stent coatings. Prog Blamed Res 6: 1-4.
  • Benimetskaya L, Loike JD, Khaled Z, Loike G, Silverstein SC, Cao L, El Khoury J, Cai T, Stein CA (1997). Mac-1 (CD11b/CD18) is an oligodeoxynucleotide-binding protein. Nat Med3:414-420.
  • Coller B (1999). Potential non-glycoprotein Ilb/IIIa effects of abciximab. Am Heart J138: 51-55.
  • Duda NT, Tumelero RT, Tognon AP (2002). Silicon carbide-coated stent: Restenosis study (SlCARS). Am JCardiol90:75H.
  • ERASER Investigators (1999). Acute platelet inhibition with abciximab does not reduce instent restenosis (ERASER study). Circulation 100: 799-806.
  • Harder C, Rzany A, Schaldach M. Coating of vascular stents with antithrombogenic amorphous silicon carbide. Prog Biomed Res 4:71-77.
  • Heublein B, Ozbek C, Pethig K (1998). Silicon carbide-coated stents: Clinical experience in coronary lesions with increased thrombotic risk. J Endovasc Surg 5: 32-36.
  • Horvath C, Welt FG, Nedelman M, Rao P, Rogers C (2002). Targeting CCR2 or CD18 inhibits experimental in-stent restenosis in primates: Inhibitory potential depends on type of injury and leukocytes targeted. Circ Res 90: 488-494.
  • Hynes RO (2002). Integrins: Bidirectional allosteric signaling machines. Cell 110: 673-687.
  • Kalnins U, Erglis A, Dinne I, Kumsars I, Jegere S (2002). Clinical outcomes of silicon carbide coated stents in patients with coronary artery disease. Med Sci Monit 8: 16-18.
  • Koch W, BottigerC, Mehilli J, von Beckerath N, Neumann FJ, Schömig A, Kastrati A (2001). Association of a CD18 gene polymorphism with a reduced risk of restenosis after coronary stenting. Am J Cordial 88: 1120-1124.
  • Lu CF, Springer TA (1997). The alpha subunit cytoplasmic domain regulates the assembly and adhesiveness of integrin lymphocyte function-associated antigen-1. J lmmunol 159: 268-278.
  • Mickelson JK, Lakkis NM, Villarreal-Levy G, Hughes BJ, and Smith CW (1996). Leukocyte activation with platelet adhesion after coronary angioplasty: A mechanism for recurrent disease? J Am Coll Cardiol28: 345-353.
  • Monnink SH, van Boven AJ, Peels HO, Tigchelaar I, de Kam PJ, Crijns HJ, van Oeveren W (1999). Silicon-carbide coated coronary stents have low platelet and leukocyte adhesion during platelet activation. J Investig Med47: 304-310.
  • Ott I, Neumann FJ, Kenngott S, Gawaz M, Schömig A (1998). Procoagulant inflammatory responses of monocytes after direct balloon angioplasty in acute myocardial infarction. Am J Cordial 82: 938-942.
  • Peter K, O'Toole TE (1995). Modulation of cell adhesion by changes in aLß2 (LFA-1,CD11a/CD18) cytoplasmic domain/cytoskeleton interaction. J Exp Med 181: 315-326.
  • Peter K, Bode C (1996). A deletion in the a-subunit locks platelet integrin aIIbß3 into a high affinity state. Blood Coag Fibrinolysis 7: 233-236.
  • Peter K, Schwarz M, Conradt C, Nordt T, Moser M, Kübier W, Bode C (1999). Heparin inhibits ligand binding to the leukocyte integrin Mac-1 (CD11b/CD18). Circulation 100: 1533-1539.
  • Plescia J, Altieri DC (1996). Activation of Mac-1 (CD11b/CD18)-bound factor X by released cathepsin G defines an alternative pathway of leucocyte initiation of coagulation. Biochem J 319: 873-879.
  • Plescia J, Conte MS, Van Meter G, Ambrosini G, Altieri DC (1998). Molecular identification of the cross-reacting epitope on alphaM beta2 integrin I domain recognized by anti-alphallb/beta3 monoclonal antibody 7E3 and its involvement in leukocyte adherence. J Biol Chem 273:20372-20377.
  • Rzany A, Schaldach M (1999). Physical properties of antithrombogenic materials--an electronic model of contact activation. Prog Blamed Res 4: 59-66.
  • Rogers C, Welt FG, Karnovsky MJ, Edelman ER (1996). Monocyte recruitment and neointimal hyperplasia in rabbits: Coupled inhibitory effects of heparin. Arterioscler Thromb Vase Biol 16: 1312-1318.
  • Rogers C, Edelman ER, Simon DI (1998). A mAb to the beta2-leukocyte integrin Mac-1 (CD11b/CD18) reduces intimai thickening after angioplasty or stent implantation in rabbits. Proc Natl Acad Sci USA 95: 10134-10139.
  • Schwarz M, Nordt T, Bode C, PeterK (2002). The GPIIb/IIIa inhibitor abciximab (c7E3) inhibits the binding of various ligands to the leukocyte integrin Mac-1 (CD11b/CD18, aMß2). Thromb Res 107: 121-128.
  • Simon DI, Xu H, Ortlepp S, Rogers C, Rao NV (1997). 7E3 monoclonal antibody directed against the platelet glycoprotein IIb/IIIa cross-reacts with the leukocyte integrin Mac-1 and blocks adhesion to fibrinogen and ICAM-I. Arterioscler Thromb Vase Biol 17: 528-535.
  • Simon DI, Dhen Z, Seifert P, Edelman ER, Ballantyne CM, Rogers C (2000). Decreased neointimal formation in Mac-1 (--/--) mice reveals a role for inflammation in vascular repair after angioplasty. J Clin Invest 105: 293-300.
  • Springer TA (1995). Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigration. Annu Rev Physiol 57: 827-872.
  • Topol EJ, Serruys PW (1998). Frontiers in interventional cardiology. Circulation 98: 1802-1820.
  • Topol EJ, Byzova TV, Plow EF (1999). Platelet GPIIb-IIIa blockera. Lancet 353: 227-231.
  • Van Belle E, Tio FO, Couffinhal T, Maillard L, Passen J, Isner JM (1997). Stent endothelialization: Time course, impact of local catheter delivery, feasibility of recombinant protein administration, and response to cytokine expedition. Circulation 95: 438-448.
  • Van Oeveren W (1999). Reduced deposition of blood formed elements and fibrin onto amorphous silicon carbide coated stainless steel. Prog Biomed Res 4: 78-83.

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