Beryllium Alters Lipopolysaccharide-Mediated Intracellular Phosphorylation and Cytokine Release in Human Peripheral Blood Mononuclear Cells

REFERENCES

• Newman , L. and Maier , L. 2003 . “ Beryllium disease ” . In Interstitial Lung Disease, , 4th ed. , Edited by: Schwarz , M. I. and King , T. E. 440 – 441 . Hamilton, Ontario , , Canada : BC Decker .
   Google Scholar
• Fontenot , A. P. and Maier , L. A. 2005 . Genetic susceptibility and immune-mediated destruction in beryllium-induced disease . Trends Immunol. , 26 : 543 – 549 .
   PubMed Web of Science ®Google Scholar
• Richeldi , L. , Sorrentino , R. and Saltini , C. 1993 . HLA-DPB1 glutamate 69: A genetic marker of beryllium disease . Science , 262 : 242 – 244 .
   PubMed Web of Science ®Google Scholar
• Maier , L. A. , McGrath , D. S. Sato , H. 2003 . Influence of MHC class II in susceptibility to beryllium sensitization and chronic beryllium disease . J. Immunol. , 171 : 6910 – 6918 .
   PubMed Web of Science ®Google Scholar
• Schwartz , D. A. 1996 . Grain dust, endotoxin, and airflow obstruction . Chest , 109 : 57S – 63S .
   PubMed Web of Science ®Google Scholar
• Michel , O. , Kips , J. Duchateau , J. 1996 . Severity of asthma is related to endotoxin in house dust . Am. J. Respir. Crit. Care Med. , 154 : 1641 – 1646 .
   PubMed Web of Science ®Google Scholar
• Kline , J. N. , Cowden , J. D. Hunninghake , G. W. 1999 . Variable airway responsiveness to inhaled lipopolysaccharide . Am. J. Respir. Crit. Care Med. , 160 : 297 – 303 .
   PubMed Web of Science ®Google Scholar
• Jagielo , P. J. , Thorne , P. S. , Watt , J. L. , Frees , K. L. , Quinn , T. J. and Schwartz , D. A. 1996 . Grain dust and endotoxin inhalation challenges produce similar inflammatory responses in normal subjects . Chest , 110 : 263 – 267 .
   PubMed Web of Science ®Google Scholar
• Arbour , N. C. , Lorenz , E. Schutte , B. C. 2000 . TLR4 mutations are associated with endotoxin hyporesponsiveness in humans . Nat. Genet. , 25 : 187 – 191 .
   PubMed Web of Science ®Google Scholar
• Becker , S. , Dailey , L. , Soukup , J. M. , Silbajoris , R. and Devlin , R. B. 2005 . TLR-2 is involved in airway epithelial cell response to air pollution particles . Toxicol. Appl. Pharmacol. , 203 : 45 – 52 .
   PubMed Web of Science ®Google Scholar
• Hollingsworth , J. W. II , Cook , D. N. Brass , D. M. 2004 . The role of Toll-like receptor 4 in environmental airway injury in mice . Am. J. Respir. Crit. Care Med. , 170 : 126 – 132 .
   PubMed Web of Science ®Google Scholar
• Dreher , K. L. , Jaskot , R. H. Lehmann , J. R. 1997 . Soluble transition metals mediate residual oil fly ash induced acute lung injury . J. Toxicol. Environ. Health , 50 : 285 – 305 .
   PubMed Web of Science ®Google Scholar
• Gao Barchowsky , F. A. , Nemec , A. A. and Fabisiak , J. P. 2004 . Microbial stimulation by Mycoplasma fermentans synergistically amplifies IL-6 release by human lung fibroblasts in response to residual oil fly ash (ROFA) and nickel . Toxicol. Sci. , 81 : 467 – 479 .
   PubMed Web of Science ®Google Scholar
• Lee , J. Y. , Atochina , O. King , B. 2000 . Beryllium, an adjuvant that promotes gamma interferon production . Infect. Immun. , 68 : 4032 – 4039 .
   PubMed Web of Science ®Google Scholar
• Chaudhary , A. , Fresquez , T. M. and Naranjo , M. J. 2007 . Tyrosine kinase SYK associates with toll-like receptor 4 and regulates signaling in human monocytic cells . Immunol. Cell. Biol. , 85 : 249 – 256 .
   PubMed Web of Science ®Google Scholar
• Chaudhary , A. , Sauer , N. N. and Gupta , G. 2004 . Beryllium-specific immune response in primary cells from healthy individuals . Toxicology , 201 : 9 – 19 .
   PubMed Web of Science ®Google Scholar
• Martinon , F. , Agostini , L. , Meylan , E. and Tschopp , J. 2004 . Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome . Curr. Biol. , 14 : 1929 – 1934 .
   PubMed Web of Science ®Google Scholar
• Boulet , I. , Ralph , S. Stanley , E. 1992 . Lipopolysaccharide- and interferon-gamma-induced expression of HCK and LYN tyrosine kinases in murine bone marrow-derived macrophages . Oncogene , 7 : 703 – 710 .
   PubMed Web of Science ®Google Scholar
• Williams , L. , Bradley , L. , Smith , A. and Foxwell , B. 2004 . Signal transducer and activator of transcription 3 is the dominant mediator of the anti-inflammatory effects of IL-10 in human macrophages . J. Immunol. , 172 : 567 – 576 .
   PubMed Web of Science ®Google Scholar
• Staples , K. J. , Smallie , T. Williams , L. M. 2007 . IL-10 induces IL-10 in primary human monocyte-derived macrophages via the transcription factor Stat3 . J. Immunol. , 178 : 4779 – 4785 .
   PubMed Web of Science ®Google Scholar
• Kasmi , K. C. , Holst , J. Coffre , M. 2006 . General nature of the STAT3-activated anti-inflammatory response . J. Immunol. , 177 : 7880 – 7888 .
   PubMed Web of Science ®Google Scholar
• Liddle , F. J. , Alvarez , J. V. , Poli , V. and Frank , D. A. 2006 . Tyrosine phosphorylation is required for functional activation of disulfide-containing constitutively active STAT mutants . Biochemistry , 45 : 5599 – 5605 .
   PubMed Web of Science ®Google Scholar
• Li , L. and Shaw , P. E. 2006 . Elevated activity of STAT3C due to higher DNA binding affinity of phosphotyrosine dimer rather than covalent dimer formation . J. Biol. Chem. , 281 : 33172 – 33181 .
   PubMed Web of Science ®Google Scholar
• Yum , H.-K. , Arcaroli , J. Kupfner , J. 2001 . Involvement of phosphoinositide 3-kinases in neutrophil activation and the development of acute lung injury . J. Immunol. , 167 : 6601 – 6608 .
   PubMed Web of Science ®Google Scholar
• Ardeshna , K. M. , Pizzey , A. R. , Devereux , S. and Khwaja , A. 2000 . The PI3 kinase, p38 SAP kinase, and NF-kappaB signal transduction pathways are involved in the survival and maturation of lipopolysaccharide-stimulated human monocyte-derived dendritic cells . Blood , 96 : 1039 – 1046 .
   PubMed Web of Science ®Google Scholar
• Martin , M. , Schifferle , R. E. , Cuesta , N. , Vogel , S. N. , Katz , J. and Michalek , S. M. 2003 . Role of the phosphatidylinositol 3 kinase-Akt pathway in the regulation of IL-10 and IL-12 by porphyromonas gingivalis lipopolysaccharide . J. Immunol. , 171 : 717 – 725 .
   PubMed Web of Science ®Google Scholar
• Molnarfi , N. , Gruaz , L. , Dayer , J. M. and Burger , D. 2007 . Opposite regulation of IL-1beta and secreted IL-1 receptor antagonist production by phosphatidylinositide-3 kinases in human monocytes activated by lipopolysaccharides or contact with T cells . J. Immunol. , 178 : 446 – 454 .
   PubMed Web of Science ®Google Scholar
• Wipf , P. and Halter , R. J. 2005 . Chemistry and biology of wortmannin . Org. Biomol. Chem. , 3 : 2053 – 2061 .
   PubMed Web of Science ®Google Scholar
• Vlahos , C. J. , Matter , W. F. , Hui , K. Y. and Brown , R. F. 1994 . A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002) . J. Biol. Chem. , 269 : 5241 – 5248 .
   PubMed Web of Science ®Google Scholar
• Tinkle , S. S. , Kittle , L. A. and Newman , L. S. 1999 . Partial IL-10 inhibition of the cell-mediated immune response in chronic beryllium disease . J. Immunol. , 163 : 2747 – 2753 .
   PubMed Web of Science ®Google Scholar
• Howard , M. , Muchamuel , T. , Andrade , S. and Menon , S. 1993 . Interleukin 10 protects mice from lethal endotoxemia . J. Exp. Med. , 177 : 1205 – 1208 .
   PubMed Web of Science ®Google Scholar
• Huang , Y. , Li , T. , Sane , D. C. and Li , L. 2004 . IRAK1 serves as a novel regulator essential for lipopolysaccharide-induced interleukin-10 gene expression . J. Biol. Chem. , 27 : 51697 – 51703 .
   Web of Science ®Google Scholar
• Fung , M. M. , Rohwer , F. and McGuire , K. L. 2003 . IL-2 activation of a PI3K-dependent STAT3 serine phosphorylation pathway in primary human T cells . Cell. Signal. , 15 : 625 – 636 .
   PubMed Web of Science ®Google Scholar
• Li , H. , Willingham , S. B. , Ting , J. P.Y. and Re , F. 2008 . Cutting edge: Inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3 . J. Immunol. , 181 : 17 – 21 .
   PubMed Web of Science ®Google Scholar
• Dostert , C. , Petrilli , V. , Van Bruggen , R. , Steele , C. , Mossman , B. T. and Tschopp , J. 2008 . Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica . Science , 320 : 674 – 677 .
   PubMed Web of Science ®Google Scholar
• Flohe , S. B. , Bruggemann , J. , Herder , C. , Goebel , C. and Kolb , H. 2002 . Enhanced proinflammatory response to endotoxin after priming of macrophages with lead ions . J. Leukoc. Biol. , 71 : 417 – 424 .
   PubMed Web of Science ®Google Scholar
• Lewis , J. B. , Messer , R. L. , McCloud , V. V. , Lockwood , P. E. , Hsu , S. D. and Wataha , J. C. 2006 . Ni(II) activates the Nrf2 signaling pathway in human monocytic cells . Biomaterials , 27 : 5348 – 5356 .
   PubMed Web of Science ®Google Scholar
• Kim , S. H. and Sharma , R. P. 2005 . Mercury alters endotoxin-induced inflammatory cytokine expression in liver: Differential roles of p38 and extracellular signal-regulated mitogen-activated protein kinases . Immunopharmacol. Immunotoxicol. , 27 : 123 – 135 .
   PubMed Web of Science ®Google Scholar
• Kimura , T. , Itoh , N. Takehara , M. 2003 . Protective effect of zinc against lipopolysaccharide/D-galactosamine-induced lethality . J. Health Sci. , 49 : 40 – 44 .
   Web of Science ®Google Scholar
• Sato , N. , Kinbara , M. Kuroishi , T. 2007 . Lipopolysaccharide promotes and augments metal allergies in mice, dependent on innate immunity and histidine decarboxylase . Clin. Exp. Allergy , 37 : 743 – 751 .
   PubMed Web of Science ®Google Scholar
• Kang , S.-Y. , Bremer , P. , Kim , K.-W. and McQuillan , J. 2006 . Monitoring metal binding in single layer Psedomonas aeruginosa biofilms using ATR-IR spectroscopy . Langmuir , 22 : 286 – 291 .
   PubMed Web of Science ®Google Scholar
• Newman , L. S. 1995 . Beryllium disease and sarcoidosis: Clinical and laboratory links . Sarcoidosis , 12 : 7 – 19 .
   PubMedGoogle Scholar
• Schurmann , M. , Lympany , P. A. Reichel , P. 2000 . Familial sarcoidosis is linked to the major histocompatibility complex region . Am. J. Respir. Crit. Care Med. , 162 : 861 – 864 .
   PubMed Web of Science ®Google Scholar
• Cantwell , A. R. Jr. 1982 . Histologic observations of variably acid-fast pleomorphic bacteria in systemic sarcoidosis: A report of 3 cases . Growth , 46 : 113 – 125 .
   PubMedGoogle Scholar
• Almenoff , P. L. , Johnson , A. , Lesser , M. and Mattman , L. H. 1996 . Growth of acid fast L forms from the blood of patients with sarcoidosis . Thorax , 51 : 530 – 533 .
   PubMed Web of Science ®Google Scholar
• Kelly , D. M. , Greene , C. M. Meachery , G. 2005 . Endotoxin up-regulates interleukin-18: potential role for gram-negative colonization in sarcoidosis . Am. J. Respir. Crit. Care Med. , 172 : 1299 – 1307 .
   PubMed Web of Science ®Google Scholar
• Chamaillard , M. , McDonald , C. and Nunez , G. 2005 . Early-onset sarcoidosis gets the nod . Blood , 105 : 912
   Web of Science ®Google Scholar
• Rossman , M. D. and Kreider , M. E. 2003 . Is chronic beryllium disease sarcoidosis of known etiology? . Sarcoidosis, Vasc. Diffuse Lung Dis. , 20 : 104 – 109 .
   PubMed Web of Science ®Google Scholar